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Topic Review
Chemistry and Biosynthesis of Melatonin
Melatonin is a ubiquitous indolamine, largely investigated for its key role in the regulation of several physiological processes in both animals and plants. In the last century, it was reported that this molecule may be produced in high concentrations by several species belonging to the plant kingdom and stored in specialized tissues. 
  • 2.5K
  • 29 Mar 2022
Topic Review
Memory Span
In psychology and neuroscience, memory span is the longest list of items that a person can repeat back in correct order immediately after presentation on 50% of all trials. Items may include words, numbers, or letters. The task is known as digit span when numbers are used. Memory span is a common measure of working memory and short-term memory. It is also a component of cognitive ability tests such as the WAIS. Backward memory span is a more challenging variation which involves recalling items in reverse order.
  • 2.5K
  • 20 Oct 2022
Topic Review
Wood-Eating Insects and Wood Eaters
Dead wood is rich in sugars and can serve as an energy source when digested, but it lacks other nutrients, preventing the growth, development, and maturation of saproxylophages. Prokaryotic N fixation partially mitigates the limitations on saproxylophages by the scarcity of N, often the most limiting nutrient, what does not mitigate co-limitation by other physiologically essential nutrients. Fungal transport can shape nutrient dynamics early in wood decay, rearranging extremely scarce nutritional composition of dead wood environment during its initial stage of decomposition and assisting saproxylophage growth and development. This nutritional enrichment of dead wood creates a nutritional niche for xylophages that allows them to grow, develop, and reach maturity. Therefore, xylophagous insects (considered as “wood-eaters”) are unable to gather the necessary amounts of nutritional elements from pure dead wood to grow and mature, but instead must utilize fungal tissues.
  • 2.5K
  • 30 Oct 2020
Topic Review
Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs) are multipotent cells which can proliferate and replace dead cells in the body. MSCs also secrete immunomodulatory molecules, creating a regenerative microenvironment that has an excellent potential for tissue regeneration.
  • 2.5K
  • 20 Jan 2021
Topic Review
MMP-13 in Osteoarthritis Treatment
Osteoarthritis (OA) is a common degenerative disease characterized by the destruction of articular cartilage and chronic inflammation of surrounding tissues. Matrix metalloproteinase-13 (MMP-13) is the primary MMP involved in cartilage degradation through its particular ability to cleave type II collagen. Hence, it is an attractive target for the treatment of OA.
  • 2.5K
  • 07 May 2021
Topic Review
Sperm Cryopreservation in Ruminant Species
Sperm cryopreservation is a powerful tool to preserve threatened animal species or for livestock breeding. However, this process is not free of disadvantages. Thus, during the cryopreservation process a significant amount of sperm suffers considerable cryodamage, which may affect sperm quality and fertility. Recently, the use of different “omics” technologies in sperm cryobiology, especially proteomics studies, has led to a better understanding of the molecular modifications induced by sperm cryopreservation, facilitating the identification of different freezability biomarkers and certain proteins that can be added before cryopreservation to enhance sperm cryosurvival. This entry provides an updated overview of the molecular mechanism involved in sperm cryodamage, as well as the molecular aspects of those novel strategies that have been developed to reduce sperm cryodamage, including  including new cryoprotectants, antioxidants, proteins, nanoparticles and vitrification.
  • 2.5K
  • 29 Oct 2020
Topic Review
Frying
Frying is one of the oldest unit operations to produce food products with a crisp texture, an aromatic flavour and a golden-brown colour. Deep-fried foods such as French fries, potato/veggie crisps are popular among consumers. Detailed insights into the frying process in terms of heat, mass (water and oil) and momentum transfers are outlined in this entry.
  • 2.5K
  • 28 Jul 2020
Topic Review
East African Lion
The East African lion is a Panthera leo melanochaita population in East Africa. During the 20th century, lion populations in this part of Africa became fragmented and declined in several range countries due to loss of habitat and prey base, poaching and killing of lions to protect livestock and human life. In 2005, a Lion Conservation Strategy was developed for East and Southern Africa. Today, lion populations are stable only in large protected area complexes. The scientific name P. l. melanochaita was proposed for the Cape lion in 1842 that was eradicated in the mid-19th century. P. l. melanochaita differs genetically from P. leo leo; the two subspecies probably diverged at least 50,000 years ago.
  • 2.5K
  • 01 Dec 2022
Topic Review
Odor Compounds in Meat
The volatile composition and odor of meat and meat products is based on the precursors present in the raw meat. These are influenced by various pre-slaughter factors (species, breed, sex, age, feed, muscle type). Furthermore, post-mortem conditions (chiller aging, cooking conditions, curing, fermentation, etc.) determine the development of meat volatile organic compounds (VOCs).
  • 2.5K
  • 08 Nov 2022
Topic Review
Amino Acid Catabolism
Amino acids have been extensively studied in nutrition, mainly as key elements for maintaining optimal protein synthesis in the body as well as precursors of various nitrogen-containing compounds. However, it is now known that amino acid catabolism is an important element for the metabolic control of different biological processes, although it is still a developing field to have a deeper understanding of its biological implications. The mechanisms involved in the regulation of amino acid catabolism now include the contribution of the gut microbiota to amino acid oxidation and metabolite generation in the intestine, the molecular mechanisms of transcriptional control, and the participation of specific miRNAs involved in the regulation of amino acid degrading enzymes. In addition, molecules derived from amino acid catabolism play a role in metabolism as they are used in the epigenetic regulation of many genes.
  • 2.5K
  • 02 Aug 2023
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