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Topic Review
Pathophysiology of Cerebral Malaria and Treatment
Plasmodium falciparum causes over 90 percent of all malaria infections. Children under the age of 5 years and pregnant women were the most susceptible groups affected by malaria. The World Health Organization (WHO) has characterized malaria as severe and uncomplicated. Delays in the detection and treatment of an uncomplicated infection of P. falciparum malaria lead to complications of severe cerebral malaria (CM). CM is usually caused by P. falciparum, but Plasmodium vivax is rarely responsible for CM complications. CM is a severe neurological complication caused by Plasmodium falciparum infection, resulting in high mortality rates. CM is characterized by brain tissue hemorrhage, the accumulation of infected red blood cells and mononuclear cells in brain microvessels, and blood-brain barrier (BBB) disruption. 
  • 1.3K
  • 11 Jul 2022
Topic Review
Nanobiotechnology for Agriculture
Nanobiotechnology in agriculture is a driver for modern-day smart, efficient agricultural practices. Nanoparticles have been shown to stimulate plant growth and disease resistance. The goal of sustainable farming can be accomplished by developing and sustainably exploiting the fruits of nanobiotechnology to balance the advantages nanotechnology provides in tackling environmental challenges.
  • 1.3K
  • 14 Mar 2021
Topic Review
Tea and Its Active Constituents in Cosmetics
Tea plant itself and its extracts together with their centuries-old tradition of use play an important role on the cosmetics market. In general, cosmetics products containing tea extracts rich in polyphenols have a positive effect on the skin appearance and ameliorate skin damage, erythema and lipid peroxidation following UV exposure.
  • 1.3K
  • 29 Mar 2022
Topic Review
Lingua Geographica
Geographic tongue, also known by several other terms,[note 1] is a condition of the mucous membrane of the tongue, usually on the dorsal surface. It is a common condition, affecting approximately 2–3% of the general population. It is characterized by areas of smooth, red depapillation (loss of lingual papillae) which migrate over time. The name comes from the map-like appearance of the tongue, with the patches resembling the islands of an archipelago. The cause is unknown, but the condition is entirely benign (importantly, it does not represent oral cancer), and there is no curative treatment. Uncommonly, geographic tongue may cause a burning sensation on the tongue, for which various treatments have been described with little formal evidence of efficacy.
  • 1.3K
  • 26 Oct 2022
Topic Review
Alopecia
Hair loss (HL), also known as alopecia or baldness, is a common clinical disorder that affects millions of people worldwide and often causes a significant source of patient distress.
  • 1.3K
  • 07 May 2021
Topic Review
Biological Quality of Soils
As is it known, soil is the basis of all activity in which man is involved. At the same time, it is the key factor for the development of the life and biodiversity of the planet's flora and fauna. Hence, as result of global warming and climate change, ecological research has recently increased its importance on the bases that extensive forest areas, act as carbon sinks mitigating greenhouse gas emissions. But no less important for investigation should be to inquire under this plant cover. Because there is a totally unimaginable and diverse world that remains in constant interactions to keep alive and from the green covering habitat to the diverse forms from small mammals to man. Man in its early days learned to manage the soil with the aim of producing food. Afterwards the exponential growth of the population was produced, and a high demand for food, caused the expansion of livestock borders, caused the devastation of large areas of forests, and generated a great impact to the soil and ecosystem. As a result, the change in land use and the application of chemicals impoverished and impairs the soil and the life that inhabits it. This is why this work highlights the importance of the biological component of soil to the context of the Amazon of Ecuador. For this reason, is important to consider different organisms as Essential Indicators of Soil Quality, mainly for the tropical soil field. In order to reach this objective, we compiled information presenting it in tables. They facilitate the interpretation of the importance of species of organisms and parameters from a biological point of view. At the same time, they can be used as a theoretical basis for the development of projects and research aimed to the management of biological soil composites.
  • 1.3K
  • 30 Oct 2020
Topic Review
MEGDEL Syndrome
MEGDEL syndrome is an inherited disorder that affects multiple body systems. It is named for several of its features: 3-methylglutaconic aciduria (MEG), deafness (D), encephalopathy (E), and Leigh-like disease (L).
  • 1.3K
  • 23 Dec 2020
Topic Review
Retinoic Acid
The retinoids are a group of compounds including vitamin A and its active metabolite all-trans-retinoic acid (ATRA). Retinoids regulate a variety of physiological functions in multiple organ systems, are essential for normal immune competence, and are involved in the regulation of cell growth and differentiation. Vitamin A derivatives have held promise in cancer treatment and ATRA is used in differentiation therapy of acute promyelocytic leukemia (APL). ATRA and other retinoids have also been successfully applied in a variety of dermatological conditions such as skin cancer, psoriasis, acne, and ichthyosis. Moreover, modulation of retinoic acid receptors and retinoid X (or rexinoid) receptors function may affect dermal cells. The studies using complex genetic models with various combinations of retinoic acid receptors (RARs) and retinoid X (or rexinoid) receptors (RXRs) indicate that retinoic acid and its derivatives have therapeutic potential for a variety of serious dermatological disorders including some malignant conditions.
  • 1.3K
  • 28 Dec 2020
Topic Review
Silk Fibroin as Contact Lenses
Fibroin is a fibrous protein that can be conveniently isolated from the silk cocoons produced by the larvae of Bombyx mori silk moth. In its form as a hydrogel, Bombyx mori silk fibroin (BMSF) has been employed in a variety of biomedical applications. When used as substrates for biomaterial-cells constructs in tissue engineering, the oxygen transport characteristics of the BMSF membranes have proved so far to be adequate. However, over the past three decades the BMSF hydrogels have been proposed episodically as materials for the manufacture of contact lenses, an application that depends on substantially elevated oxygen permeability.
  • 1.3K
  • 26 May 2021
Topic Review
Infrared Thermography in Large Ruminants
Infrared thermography (IRT) is a tool that is being used increasingly with farm animals due to society’s growing interest in animal welfare.
  • 1.3K
  • 09 Aug 2021
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