Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort:
Hottest Latest Alphabetical (A-Z) Alphabetical (Z-A)
Type:
All Topic Review Biography
Topic Review
Anti-Cancer Properties of Flaxseed Proteome
Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These properties are attributed to their ability to inhibit cancer cell proliferation, induce apoptosis, and interfere with cancer cell signaling pathways, ultimately leading to the inhibition of metastasis.
  • 243
  • 28 Nov 2023
Topic Review
Cell Cultures in the Autoimmune Connective Tissue Diseases
Cell cultures are an important part of the research and treatment of autoimmune connective tissue diseases. By culturing the various cell types involved in autoimmune connective tissue diseases (ACTDs), researchers are able to broaden the knowledge about these diseases that, in the near future, may lead to finding cures. Fibroblast cultures and chondrocyte cultures allow scientists to study the behavior, physiology and intracellular interactions of these cells.
  • 110
  • 24 Nov 2023
Topic Review
Ageing and Inflammation in Periodontium
Periodontitis is a ubiquitous chronic inflammatory disease characterized by the gradual destruction of the periodontal ligament and alveolar bone, leading to periodontal pocket formation and gingival recession. Ageing is a primary risk factor for the development of periodontitis, exacerbating alveolar bone loss and leading to tooth loss in the geriatric population.
  • 139
  • 24 Nov 2023
Topic Review
Nanoscale Materials for Scaffold Structure and Function
Bone regeneration and repair are complex processes with the potential of added complications, like delayed repair, fracture non-union, and post-surgical infections. These conditions remain a challenge globally, pressurizing the economy and patients suffering from these conditions. Applications of nanotechnology (NBT) in the field of medicine have provided a medium for several approaches to support these global challenges. Tissue engineering is one such field that has been on the rise in the past through the utilization of NBT for addressing the challenges related to bone regeneration.
  • 192
  • 22 Nov 2023
Topic Review
Role of Extracellular Vesicles in Hepatocellular Carcinoma
Extracellular vesicles (EVs) play critical roles in intercellular communication by transporting bioactive cargo to recipient cells. EVs have been implicated in a range of physiological and pathological processes, including tumor progression, metastasis, immune modulation, and drug resistance.
  • 129
  • 20 Nov 2023
Topic Review
Clinical Applications of Amnion-Derived Membranes
Biological tissues from various anatomical sources have been utilized for tissue transplantation and have developed into an important source of extracellular scaffolding material for regenerative medicine applications. Tissue scaffolds ideally integrate with host tissue and provide a homeostatic environment for cellular infiltration, growth, differentiation, and tissue resolution. The human amniotic membrane is considered an important source of scaffolding material due to its 3D structural architecture and function and as a source of growth factors and cytokines. This tissue source has been widely studied and used in various areas of tissue repair including intraoral reconstruction, corneal repair, tendon repair, microvascular reconstruction, nerve procedures, burns, and chronic wound treatment. 
  • 160
  • 15 Nov 2023
Topic Review
Alveolar Type 2 Epithelial Cell Organoid Culture Methods
Lung diseases rank third in terms of mortality and represent a significant economic burden globally. Scientists have been conducting research to better understand respiratory diseases and find treatments for them. An ideal in vitro model must mimic the in vivo organ structure, physiology, and pathology. Organoids are self-organizing, three-dimensional (3D) structures originating from adult stem cells, embryonic lung bud progenitors, embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs). These 3D organoid cultures may provide a platform for exploring tissue development, the regulatory mechanisms related to the repair of lung epithelia, pathophysiological and immunomodulatory responses to different respiratory conditions, and screening compounds for new drugs. To create 3D lung organoids in vitro, both co-culture and feeder-free methods have been used. However, there exists substantial heterogeneity in the organoid culture methods, including the sources of type 2 alveolar cells (AT2) cells, media composition, and feeder cell origins. 
  • 97
  • 14 Nov 2023
Topic Review
Patient-Derived Xenografts for Cancer Research
The patient-derived xenograft (PDX) model is the in vivo standard for cancer research as a preclinical platform.
  • 169
  • 03 Nov 2023
Topic Review
Extracellular Vesicles in Myocardial Injury and Healing Response
Increased prevalence of cardiovascular disease and potentially life-threatening complications of myocardial infarction (MI) has led to emerging therapeutic approaches focusing on myocardial regeneration and restoration of physiologic function following infarction. Extracellular vesicle (EV) technology has gained attention owing to the biological potential to modulate cellular immune responses and promote the repair of damaged tissue. Also, EVs are involved in local and distant cellular communication following damage and play an important role in initiating the repair process. Vesicles derived from stem cells and cardiomyocytes (CM) are of particular interest due to their ability to promote cell growth, proliferation, and angiogenesis following MI. 
  • 145
  • 02 Nov 2023
Topic Review
Extracellular Matrix (ECM)
In tissues and organs, the extracellular matrix (ECM) is an essential extracellular element that surrounds cells, characterised by its sophisticated nanoarchitecture. It is a highly hydrated structure composed of cell-secreted proteins (e.g., collagen, fibronectin, elastin, etc.), macromolecules (e.g., polysaccharides, hyaluronan, glycosaminoglycans—GAGs—and proteoglycans—PGs), and specialised soluble factors (e.g., ions, growth factor, cytokines, and hormones).
  • 172
  • 09 Oct 2023
  • Page
  • of
  • 28
Featured Entry Collections
>>

Featured Books

>>
Encyclopedia of Social Sciences
Encyclopedia of COVID-19
Encyclopedia of Fungi
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Feedback