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Topic Review
Aetiology and Pathogenesis of Vitiligo
Vitiligo is an acquired, chronic condition characterised by depigmentation of the epidermis or by destruction/loss of melanin. Skin cells (melanocytes) are responsible for producing melanin, the substance that gives pigmentation to the skin. Although there is no specific ethnic group, gender, or skin type that is more prone to vitiligo than others, it can affect anyone. Even though vitiligo is typically thought of as a cosmetic disorder, its effects on the physical and psychosocial health of sufferers cannot be ignored.
  • 243
  • 09 Jun 2023
Topic Review
Control Strategies for Mosquito-Borne Diseases
Mosquito-borne diseases are spread by the bite of infected female mosquitoes. The main mosquito-borne diseases include malaria, Chikungunya, Zika, Dengue, West Nile, yellow fever, Rift Valley fever, Lymphatic filariasis, and tick-borne encephalitis. Various chemical, biological, and mechanical methods are used to control mosquito-borne diseases hence reducing their burden.
  • 205
  • 13 Mar 2023
Topic Review
Severe Falciparum Malaria
Plasmodium falciparum can cause a severe disease with high mortality. A major factor contributing to the increased virulence of P. falciparum, as compared to other human malarial parasites, is the sequestration of infected erythrocytes in the capillary beds of organs and tissues. This sequestration is due to the cytoadherence of infected erythrocytes to endothelial cells.
  • 177
  • 02 Aug 2023
Topic Review
Neuroprotective Potential of Cordyceps Extracts
Cordyceps, also known as “zombie fungus”, is a non-poisonous mushroom that parasitizes insects for growth and development by manipulating the host system in a way that makes the victim behave like a “zombie”. These species produce promising bioactive metabolites, like adenosine, β-glucans, cordycepin, and ergosterol. Cordyceps has been used in traditional medicine due to its immense health benefits, as it boosts stamina, appetite, immunity, longevity, libido, memory, and sleep. Neuronal loss is the typical feature of neurodegenerative diseases (NDs) (Alzheimer’s disease (AD), Parkinson’s disease (PD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS)) and neurotrauma. Both these conditions share common pathophysiological features, like oxidative stress, neuroinflammation, and glutamatergic excitotoxicity. 
  • 72
  • 01 Mar 2024
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