Topic Review
Microalgae Impact on Oral Health
Microalgae and cyanobacteria could represent a potential natural alternative to antibiotic, antiviral, or antimycotic therapies, as well as a good supplement for the prevention and co-adjuvant treatment of different oral diseases.
  • 1.5K
  • 24 Nov 2020
Topic Review
Micro-Implants in Orthodontics and Dentofacial Orthopaedics
Anchorage is one of the most important elements for successful orthodontic treatment. Traditionally, orthodontics employed teeth and extraoral or intraoral appliances for anchorage, often relying on the patient compliance for its effectiveness. Micro-implants (OMIs), also known in orthodontics as temporary anchorage devices (TAD) or mini-implants or mini-screws have been used to realize difficult orthodontic movements. Orthodontic mini-implants can be a powerful aid in resolving challenging malocclusions that require increased anchorage potential. Their use is versatile, minimally invasive, and proves a good ratio between costs and benefits of orthodontic treatments.
  • 1.1K
  • 29 Nov 2021
Topic Review
Melatonin and Periodontitis-Related Systemic Diseases
Periodontitis has become the main reason for tooth loss/edentulism in adults worldwide. It is also linked closely with other systemic diseases such as cardiovascular disease, Alzheimer’s disease, diabetes, and cancer, thus profoundly impairing people’s quality of life. As the most common chronic inflammatory disease of humans, periodontitis has brought about huge socioeconomic impacts and healthcare costs. Periodontitis as a highly prevalent chronic infection/inflammatory disease can eventually lead to tooth loss and masticatory dysfunction. It also has a negative impact on general health and largely impairs quality of life. The tissue destruction during periodontitis is mainly caused by the excessive immune–inflammatory response; hence, how to modulate the host’s reaction is of profound importance for effective periodontal treatment and tissue protection. Melatonin, as an endogenous hormone exhibiting multiple biological functions such as circadian rhythm regulation, antioxidant, and anti-inflammation, has been widely used in general healthcare. The application of melatonin as an adjunctive approach in the treatment of periodontitis and periodontitis-related systemic comorbidities is witnessed. 
  • 364
  • 02 Dec 2022
Topic Review
Medication-Related Osteonecrosis of the Jaw
Medication-related osteonecrosis of the jaw (MRONJ) has become a well-known side effect of antiresorptive, and antiangiogenic drugs commonly used in cancer management.
  • 488
  • 11 May 2021
Topic Review
Medication-Related Osteonecrosis of Jaw (MRONJ)
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents, and it is also a potentially painful and debilitating condition.
  • 512
  • 11 Oct 2021
Topic Review
Medication-Induced Dry Mouth
Dry mouth is common among older people, affecting between 20% and 30% of those over 65. There are two aspects to the condition. Salivary gland hypofunction (SGH) is the state of having low salivary flow, while xerostomia refers to the subjective sensation of dry mouth.
  • 426
  • 21 Oct 2021
Topic Review
Medical and Dental Applications of Titania Nanoparticles
Titanium oxide (TiO2) nanoparticles are successfully employed in human food, drugs, cosmetics, advanced medicine, and dentistry because of their non-cytotoxic, non-allergic, and bio-compatible nature when used in direct close contact with the human body. These NPs are the most versatile oxides as a result of their acceptable chemical stability, lower cost, strong oxidation properties, high refractive index, and enhanced aesthetics. These NPs are fabricated by conventional (physical and chemical) methods and the latest biological methods (biological, green, and biological derivatives), with their advantages and disadvantages in this epoch. The significance of TiO2 NPs as a medical material includes drug delivery release, cancer therapy, orthopedic implants, biosensors, instruments, and devices, whereas their significance as a dental biomaterial involves dentifrices, oral antibacterial disinfectants, whitening agents, and adhesives. In addition, TiO2 NPs play an important role in orthodontics (wires and brackets), endodontics (sealers and obturating materials), maxillofacial surgeries (implants and bone plates), prosthodontics (veneers, crowns, bridges, and acrylic resin dentures), and restorative dentistry (GIC and composites).
  • 784
  • 02 Nov 2022
Topic Review
Maxillary Anterior Teeth Dimensions and Relative Width Proportions
Predictable results in the aesthetic treatment of anterior teeth can be obtained by resorting to the concept of dental aesthetics and, in particular, defining the ideal tooth dimensions and proportions to obtain a harmonious smile.
  • 269
  • 18 Jan 2024
Topic Review
Matrix Metalloproteinases in Dental and Periodontal Tissues
Matrix metalloproteinases (MMPs) are significant proteases, of evident contribution in dental and periapical tissue development, health and disease processes, with promising potential for use as diagnostic and prognostic disease biomarkers. Continuing understanding of their role in pathogenesis and progress of different dental, periapical and periodontal lesions, as well as in dentine-pulp wound healing could be a keystone to future diagnostic and therapeutic regimens.
  • 598
  • 25 Aug 2022
Topic Review
Matrix Metalloproteinases and Temporomandibular Joint Disorder
Temporomandibular disorders (TMD) are progressive degenerative disorders that affect the components of the temporomandibular joint (TMJ), characterized by pain and limitations in function. Matrix metalloproteinases (MMP) are enzymes involved in physiological breakdown of tissue that can have a pathological effect from an increase in activity during inflammation.
  • 396
  • 06 May 2023
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