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Topic Review
Biomimetic 3D Scaffolds to Reproduce Periodontal Ligament Microenvironment
The periodontium is a complex system composed of gingiva, periodontal ligament (PDL), cementum, and alveolar bone, featuring a hierarchically compartmentalized architecture. The homeostasis of this system is maintained by the PDL, a specialized connective tissue, which is located between the cementum and alveolar bone and articulates (gomphosis) the teeth to the jaws. Embryologically, PDL derives from the dental follicle cells under the guidance of Hertwig’s epithelial root sheath (HERS), which secrete numerous epithelium-derived factors before obliterating almost completely.
  • 615
  • 05 Dec 2022
Topic Review
Additively Manufactured Polylactic Acid in Dentistry
Additive manufacturing (AM), which is also called rapid prototyping/3D printing/layered manufacturing, can be considered as a rapid conversion between digital and physical models. One of the most used materials in AM is polylactic acid (PLA), which has advantageous material properties such as biocompatibility, biodegradability, and nontoxicity. For many medical applications, it is considered as a leading biomaterial. In dentistry, in addition to its uses in dental models (education, teaching, simulation needs), it can be used for therapeutic objectives and tissue engineering.
  • 603
  • 28 Jun 2023
Topic Review
Outcomes of Titanium and Zirconia Implant Abutments
The characteristics of the implant prosthetic abutment are an influential factor which may impact early bone remodeling and soft tissue integration. The abutment material influences the response of both the soft and hard tissues surrounding an implant, making the choice of the prosthetic abutment a crucial phase for the success of implant-supported rehabilitations.
  • 602
  • 30 Aug 2022
Topic Review
Endotoxin-Secreting Bacteria in Periodontal Disease
The LPS is recognized by the complex TLR4/MD2, mediated by CD14 and accessory protein LBP, which induces the activation of several transcriptional regulators like factor nuclear kB (NF-kB), activator protein 1 (AP-1) and interferon (IFN) regulatory factors, leading to the expression of genes involved in the host immune response.
  • 599
  • 13 Sep 2021
Topic Review
Amelioration Strategies for Silver Diamine Fluoride
Topical cariostatic agents have become a reasonable alternative for managing dental caries in young children. Silver diamine fluoride (SDF) is a practical topical approach to arrest caries and avoid extensive and risky dental treatment. The rapid oxidation of ionic silver darkens demineralised tooth structure permanently. In this regard, nano-metallic antimicrobials could augment or substitute for silver, and thereby enhance SDF aesthetic performance.
  • 598
  • 07 Apr 2023
Topic Review
Effects of Prosthetic Restorative Biomaterials on the Periodontium
The success of a prosthetic treatment is closely related to the periodontal health of the individual. The periodontium constitutes the tissues that support the teeth. It is made up of two soft tissues (which are the gingiva and periodontal ligament) and two hard tissues (which are the root cementum and alveolar bone).
  • 599
  • 31 Jan 2023
Topic Review
Periodontal Diseases
Periodontal diseases, in the light of the new classification, have been divided into three general categories: gum disease, periodontitis, and other conditions affecting the periodontium.
  • 592
  • 14 Apr 2021
Topic Review
Biomimetic Implant Surfaces
The increased use of dental implants in oral rehabilitation has been followed by the development of new biomaterials as well as improvements in the performance of biomaterials already in use inspired by the properties of the tissues to be replaced. An implant is considered osseointegrated when there is no relative movement between the implant and the bone and no symptoms under a loading force. It is now known that surface topography is one of the key biomimetic factors that can directly affect the proliferation, structure, and alignment of human cells and their function and is also considered to be a critical determinant of cell adhesion.
  • 590
  • 24 Jun 2022
Topic Review
Barrier Membrane in Regenerative Therapy
Guided bone and tissue regeneration remains an integral treatment modality to regenerate bone surrounding teeth and dental implants. Barrier membranes have been developed and produced commercially to allow space for bone regeneration and prevent the migration of unwanted cells. Ideal membrane properties, including biocompatibility, sufficient structural integrity and suitable shelf life with easy clinical application, are important to ensure good clinical regenerative outcomes. Membranes have various types, and their clinical application depends on the origin, material, structure and properties. 
  • 590
  • 11 May 2022
Topic Review
3D-Printed Splints Therapy for Temporomandibular Disorders
In the field of dentistry, digital technology is developing very quickly. There is an increasing demand for the most efficient use of expensive digital equipment. More and more dental practices are using digital scanners and digital facebows. It is an excellent option to improve 3D splint therapy in temporomandibular disorders. Dental offices and dental laboratories will rapidly adopt 3D-printed orthodontic appliances. The benefits are its accuracy and a light workload. It is precise, long-lasting, less expensive and quicker than the conventional method.
  • 590
  • 25 May 2023
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