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Topic Review
Economic Value Added as Universal Financial Metric
Previous research into Economic Value Added (EVA) has extensively described it as a business metric of firms. Still, no studies have confirmed or denied that EVA is a universal metric and that one may use EVA in unstable markets in the same way as in stable and developed economies. Meanwhile, the green energy revolution, ensuring carbon neutrality through green innovations, requires enormous investments, and the projects realised must be appropriately tailored. These projects are realised by different firms, including those from developing countries, and investors need solid financial metrics.
  • 1.5K
  • 21 Mar 2022
Topic Review
Capacity Sizing of Battery–Supercapacitor Hybrid Energy Storage System
A battery–supercapacitor hybrid energy storage system is investigated as a solution to reduce the high-power delivery stress on the battery. An optimally-sized system can further enhance the storage and cost efficiency.
  • 1.5K
  • 17 Jun 2022
Topic Review
Constraints to Cowpea Production
Climate change and variability trends affect crop yields both directly and indirectly. Direct impacts include effects caused by a modification of physical characteristics such as low or high atmospheric temperature, soil fertility level, and water deficiency or erratic rainfall distribution in specific crop production systems. Indirect effects are those that affect production through changes in other species such as pollinators, insect pests, diseases, and weeds. These indirect effects can play a significant role in the production and productivity of cowpea. These limiting factors can broadly be termed abiotic and biotic stresses, resulting in climatic variations and ultimately reducing cowpea yield potential and its productivity.
  • 1.5K
  • 27 Jun 2022
Topic Review
Natural Products against Oxidative Stress in Multiple Sclerosis
Multiple sclerosis (MS) is an autoimmune-mediated degenerative disease of the central nervous system (CNS) characterized by immune cell infiltration, demyelination and axonal injury. Oxidative stress-induced inflammatory response, especially the destructive effect of immune cell-derived free radicals on neurons and oligodendrocytes, is crucial in the onset and progression of MS. Therefore, targeting oxidative stress-related processes may be a promising preventive and therapeutic strategy for MS. Animal models, especially rodent models, can be used to explore the in vivo molecular mechanisms of MS considering their similarity to the pathological processes and clinical signs of MS in humans and the significant oxidative damage observed within their CNS. Consequently, these models have been used widely in pre-clinical studies of oxidative stress in MS. To date, many natural products have been shown to exert antioxidant effects to attenuate the CNS damage in animal models of MS.
  • 1.5K
  • 23 Aug 2022
Topic Review
List of Ariane Launches (2010–2019)
This is a list of launches performed or scheduled to be performed by Ariane carrier rockets between 2010 and 2019. Since 2004, only the Ariane 5 is in service, operating in the ECA and ES configurations.
  • 1.5K
  • 08 Oct 2022
Topic Review
Quality Assurance Agency for Higher Education
The Quality Assurance Agency for Higher Education (QAA) is the independent body that checks on standards and quality in UK higher education. It conducts quality assessment reviews, develops reference points and guidance for providers, and conducts or commissions research on relevant issues. QAA checks how universities, colleges and alternative providers of UK higher education maintain their academic standards and quality. It does this through external peer review. Reviewers check that the 19 expectations of the Quality Code, agreed and recognised by the UK higher education sector, are met. It also provides advice to the Privy Council of the United Kingdom, on institutions' requests for degree awarding powers and the right to be called a university. In addition to its role in sustaining the reputation of UK higher education, QAA also regulates the Access to Higher Education Diploma, a qualification that enables individuals without A Levels or the usual equivalent to enter higher education. QAA works closely with other organisations that have an interest in the reputation of UK higher education, including the Higher Education Academy, Universities UK and GuildHE.
  • 1.5K
  • 19 Oct 2022
Topic Review
Performance and Modelling of AC Transmission
Performance modelling is the abstraction of a real system into a simplified representation to enable the prediction of performance. The creation of a model can provide insight into how a proposed or actual system will or does work. This can, however, point towards different things to people belonging to different fields of work. Performance modelling has many benefits, which includes: A model will often be created specifically so that it can be interpreted by a software tool that simulates the system's behaviour, based on the information contained in the performance model. Such tools provide further insight into the system's behaviour and can be used to identify bottlenecks or hot spots where the design is inadequate. Solutions to the problems identified might involve the provision of more physical resources or change in the structure of the design. Performance modelling is found helpful, in case of: Modelling of a transmission line is done to analyse its performance and characteristics. The gathered information vis simulating the model can be used to reduce losses or to compensate these losses. Moreover, it gives more insight into the working of transmission lines and helps to find a way to improve the overall transmission efficiency with minimum cost.
  • 1.5K
  • 01 Nov 2022
Topic Review
Weil’s Disease
Leptospirosis is one of the most widespread and dangerous zoonoses in the world. The main cause of death in leptospirosis is the development of a severe form of leptospirosis—Weil’s disease, which affects the kidneys, lungs, and liver, which are a “triad” of target organs in leptospirosis.
  • 1.5K
  • 22 Dec 2022
Topic Review
Composition and Industrial Applications of Phytochemical
Phytochemicals are versatile plant secondary metabolites with therapeutic properties. Lemongrass is well-known for its antioxidant, anti-microbial, anti-inflammatory, anti-hypertensive, anti-diabetic, anti-mutagenicity, anxiolytic properties, and for its hypoglycemic and hypolipidemic activities. Therefore, it is widely used in pharmaceuticals, food, feed, and the cosmetics industry. Lemongrass contains phenolic metabolites (including phenolic acids, flavonoids, stilbenes, and lignans), terpenoids, and alkaloids, which are potent bioactive ingredients. Lemongrass is a precious medicinal plant. 
  • 1.5K
  • 06 Feb 2023
Topic Review
Brain Derived Neurotrophic Factor
Brain-derived neurotrophic factor (BDNF) was named after it was first extracted from porcine brain tissue and identified as a survival factor for neuronal populations that are not responsive to NGF. Beyond its role in neurons, BDNF is also released by keratinocytes, melanocytes, fibroblasts, endothelial cells, platelets, and several immune cells such as T cells, B cells, monocytes, macrophages, mast cells, and eosinophils.
  • 1.5K
  • 30 Mar 2023
Topic Review
Membrane Fabrication Using Recycled Waste
Polymeric membranes are generally manufactured using a variety of monomers/polymers, including polystyrene, polysulfone (PSF), polyether sulfone (PES), polyaniline, polyvinylidene fluoride (PVDF), and others. The industrial manufacturing of these chemical compounds causes significant greenhouse gas emissions. In addition, the application of these monomer/polymer compounds in daily necessities has been posing a massive burden for their post-utilization disposal. The emergence of waste and its recycling potential has attracted attention to its application in membrane fabrication. The utilization of recycled waste for fabricating the membranes can help in reducing the environmental impact by 2× amount (i.e., eliminate the use of polymer for membrane fabrication and its associated environmental impact and mitigating the effect of waste on the environment via its utilization), thus helping in maintaining environmental sustainability.
  • 1.5K
  • 19 Feb 2024
Topic Review
Auraptene enhances Blood brain barrier
The blood-brain barrier (BBB) is a selectively permeable barrier that divides the central nervous system (CNS) from the peripheral circulation, preventing infectious substances and immune cells from entering the CNS.
  • 1.5K
  • 24 Mar 2021
Topic Review
Microbial Metabolites in Colorectal Cancer
Colorectal cancer (CRC) is one of the leading cancers that cause cancer-related deaths worldwide. The gut microbiota has been proved to show relevance with colorectal tumorigenesis through microbial metabolites. By decomposing various dietary residues in the intestinal tract, gut microbiota harvest energy and produce a variety of metabolites to affect the host physiology. However, some of these metabolites are oncogenic factors for CRC.
  • 1.5K
  • 27 Apr 2021
Topic Review
NDT Methodology for Copper-Based Artifacts
The great archaeological and artistic value of historic copper-based artifacts from various archaeological sites of Greece results in the restriction or even the prohibition of sampling, settling the need for the employment of non-destructive testing (NDT) techniques. X-ray fluorescence (XRF), fiber optics diffuse reflectance spectroscopy (FORS) and scanning electron microscopy coupled with an energy dispersive X-ray detector (ESEM-EDX).
  • 1.5K
  • 06 Jul 2021
Topic Review
Vietnam SciMath Database Project
The Vietnam SciMath Database Project is a product of the mathematical research history initiative led by Professor Ngô Bảo Châu, a Vietnamese-French mathematician who won the Fields Medal in 2010.
  • 1.5K
  • 19 Jul 2021
Topic Review
Human primary B Lymphocytes Transfection
B lymphocytes (B cells) are a key component of the human immune system. They can be isolated from peripheral blood or tonsils and be expanded in culture after activation by mitogenic agents. Here, it is demonstrated that a well-defined 24-armed poly(2-dimethylamino) ethyl methacrylate (PDMAEMA, 755 kDa) nano-star is able to reproducibly elicit high transgene expression (40%) at sufficient residual viability (69%) in primary human B cells derived from tonsillar tissue.
  • 1.5K
  • 24 Aug 2021
Topic Review
Advantages/Disadvantages/Limitations of Chemotaxis Assays for Campylobacter spp.
Chemotaxis directed motility of intestinal bacteria such as Campylobacter jejuni could enable the cells to move toward favourable conditions and away from hazardous ones. Reproducible qualitative and quantitative assessment of bacterial chemotactic motility, particularly in response to chemorepellent effectors, is experimentally challenging. Several established chemotaxis assays currently used to investigate Campylobacter jejuni chemotaxis are compared, with the aim of improving the correlation between different studies and establishing the best practices.
  • 1.5K
  • 11 Feb 2022
Topic Review
Mutations of Osteogenesis Imperfecta
Osteogenesis Imperfecta is a rare genetic metabolic disease of the bone system with an autosomal dominant or a recessive type of inheritance. There are also X-linked forms and sporadic cases of this disease. The frequency of the disease in general varies from 1:15,000 to 1:20,000.
  • 1.5K
  • 29 Mar 2022
Topic Review
Multilingual Pedagogies in Norwegian Schools
Teachers in Norway have been increasingly faced with the challenge of adapting their instruction methods to address the needs of minority-language students. It seems to indicate that multilingual practices are being introduced in Norwegian classrooms. However, they often rely on majority languages, such as English and Norwegian. Some teachers have been found to employ minority languages to support learners’ English writing in drafts. Minority languages in Norwegian schools tend to be regarded as less valuable than Norwegian and English.
  • 1.5K
  • 29 Jun 2022
Topic Review
Tumor Necrosis Factor Alpha
Tumor necrosis factor (TNF, cachexin, or cachectin; once named as tumor necrosis factor alpha or TNFα) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNF is a member of the TNF superfamily, consisting of various transmembrane proteins with a homologous TNF domain. The primary role of TNF is in the regulation of immune cells. TNF, being an endogenous pyrogen, is able to induce fever, apoptotic cell death, cachexia, inflammation and to inhibit tumorigenesis and viral replication and respond to sepsis via IL1- & IL6-producing cells. Dysregulation of TNF production has been implicated in a variety of human diseases including Alzheimer's disease, cancer, major depression, psoriasis and inflammatory bowel disease (IBD). Though controversial, studies of depression and IBD are currently being linked to increased levels of TNF. Recombinant TNF is used as an immunostimulant under the INN tasonermin. TNF can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
  • 1.5K
  • 10 Oct 2022
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