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Topic Review
Plant Growth-Promoting Rhizobacteria
Plant growth-promoting bacteria (PGPR) are soil bacteria living in the rhizosphere which, through the secretion of various regulatory molecules, are involved in promoting plant growth and development. They can be found associated with the roots (rhizosphere), with the leaves (phyllosphere), or within the plant (endosphere). The endophytes (PGPE) are generally the most effective in supporting growth; being inside the plant tissues, they can communicate with the host plant and exert their beneficial effect much more efficiently.
  • 6.2K
  • 28 Feb 2022
Topic Review
Direct Democracy
Direct democracy or pure democracy is a form of democracy in which people decide on policy initiatives directly. This differs from the majority of most currently established democracies, which are representative democracies.
  • 6.2K
  • 26 Oct 2022
Topic Review
Chinese Alchemy
Chinese alchemy is an ancient Chinese scientific and technological approach to alchemy, a part of the larger tradition of Taoist body-spirit cultivation developed from the traditional Chinese understanding of medicine and the body. According to original texts such as the Cantong qi, the body is understood as the focus of cosmological processes summarized in the five agents, or wu xing, the observation and cultivation of which leads the practitioner into greater alignment with the operation of the Tao, the great cosmological principle of everything. Therefore, the traditional view in China is that alchemy focuses mainly on the purification of one's spirit and body in the hopes of gaining immortality through the practice of Qigong and/or consumption and use of various concoctions known as alchemical medicines or elixirs, each of which having different purposes. Pao zhi (Pao chi) cites the pharmacological processing (of Chinese materia medica) as used in the practice of Traditional Chinese Medicine, such as honey or wine frying and roasting with toxic metals such as mercury, lead, and arsenic. According to J.C. Cooper's Chinese Alchemy: The Taoist Quest for Immortality, Taoism had two distinct parts, the classical Tao Chia, which was mystical and stemmed primarily from Laozi and Zhuangzi, and the more popular Tao Chiao, which was the popular, magical and alchemical side of Taoism. Cooper states that a common viewpoint is that "classical Taoism [Daoism] was the original but was too austere and rarefied for the general populace ... [but] Tao Chiao fulfilled the day-to-day needs of the people."
  • 6.2K
  • 16 Nov 2022
Topic Review
Mechanism of CRISPR/Cas Based Detection
In the pace of time, numerous platforms for rapid nucleic acid (NA) detection have been developed; however, they may not be able to satisfy the ASSURED (Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment-free and Deliverable to end-users) parameters set by the World Health of Organization at the same time. Recent studies have established that the CRISPR/Cas system possesses the potential to fulfil ASSURED criteria and demonstrated that it may be repurposed for the detection of contaminants, enzymes, proteins, analytes, and plant diseases, rather than being limited to clinical settings and nucleic acids. Several platforms have yet to be translated into clinical applications and must be brought into clinical settings from the laboratory. 
  • 6.2K
  • 08 Jun 2022
Topic Review
BMW 6 Series (E24)
The BMW E24 is the first generation of BMW 6 Series grand tourer coupes and was produced from January 1976 to April 1989. It replaced the E9 coupes and was, after a 16-year hiatus, succeeded by the E63 6 Series in 2004. The E24 was produced solely in a 2-door coupe body style. Aside from the M635CSi/M6 models, the E24 was powered by a range of M30 straight-6 engines. The M635CSi is the first of the BMW M6 model line and is the second true "M car" produced after the BMW M1. The M635CSi is powered by the M88/3 straight-6 engine. In North America, the vehicle is badged simply as "M6" and is powered by the detuned S38 straight-6 engine, which has a lower compression ratio and uses a catalytic converter. Although the 8 Series was released as production of the E24 was ending, the 8 Series is considered a separate model line and therefore not a true successor to the E24.
  • 6.2K
  • 18 Oct 2022
Topic Review
The Green Supply Chain Management
Green supply chain management (GSCM) involves environmental concerns in supply chain activities to minimize ecological impacts. The aim of GSCM is to find a balance between economic and environmental activities. GSCM deals with the concept of sustainability of the entire supply chain network along with providing green products or services to customers.
  • 6.2K
  • 25 Oct 2022
Topic Review
Starch-Based Biodegradable Films for Food Packaging
The use of biodegradable packaging material as an alternative to conventional petrochemical-based polymers is based on the environmental issues associated with conventional materials. Starch-based biodegradable films can be applied in food packaging. It was evident that starch stands out among biopolymers due to its abundance and cost effectiveness.
  • 6.2K
  • 07 Apr 2022
Topic Review
Disinformation
Disinformation is false or misleading information that is spread deliberately to deceive. This is a subset of misinformation, which may also be unintentional. The English word disinformation is a loan translation of the Russian dezinformatsiya, derived from the title of a KGB black propaganda department. Joseph Stalin coined the term, giving it a French-sounding name to claim it had a Western origin. Russian use began with a "special disinformation office" in 1923. Disinformation was defined in Great Soviet Encyclopedia (1952) as "false information with the intention to deceive public opinion". Operation INFEKTION was a Soviet disinformation campaign to influence opinion that the U.S. invented AIDS. The U.S. did not actively counter disinformation until 1980, when a fake document reported that the U.S. supported apartheid. The word disinformation did not appear in English dictionaries until the late-1980s. English use increased in 1986, after revelations that the Reagan Administration engaged in disinformation against Libyan leader Muammar Gaddafi. By 1990, it was pervasive in U.S. politics; and by 2001 referred generally to lying and propaganda.
  • 6.2K
  • 14 Oct 2022
Topic Review
Premature Termination Codons
Premature termination codons (PTCs) are stop codons arising from nonsense variants converting a sense codon into a termination signal, i.e. UAA, UAG or UGA. PTCs arising from mutations may, at low frequency, be misrecognized and result in PTC suppression, named ribosome readthrough, with production of full-length proteins through the insertion of a subset of amino acids. Since some drugs have been identified as readthrough inducers, this fidelity drawback has been explored as a therapeutic approach in several models of human diseases caused by nonsense mutations.
  • 6.2K
  • 23 Dec 2020
Topic Review
Climate Change on Tea
Even though climate change is having an increasing impact on tea plants, systematic reviews on the impact of climate change on the tea system are scarce. This study was undertaken to assess and synthesize the knowledge around the impacts of current and future climate on yield, quality, and climate suitability for tea; the historical roots and the most influential papers on the aforementioned topics; and the key adaptation and mitigation strategies that are practiced in tea fields.
  • 6.2K
  • 14 Apr 2021
Topic Review
D-10 Tank Gun
The D-10 is a Soviet 100 mm tank gun developed in late World War II. It originally equipped the SU-100 tank destroyers and was later selected for the T-55 tank, equipping these as late as 1979. On the T-55 the D-10 continues to be in active service in many countries.
  • 6.2K
  • 19 Oct 2022
Topic Review
Crash Boats of World War 2
Crash boats, at the time known as "aircraft rescue boat" or "air-sea rescue boat" were wooden speedboats built to rescue the crew of downed United States and other Allies aircraft during World War II. US boats came from observation of British experience with High-speed launches during the Battle of Britain. By the end of World War II America had produced 300,000 planes, creating a need to have crash rescue boats stationed around the globe. These boats were fast boats used to rescue pilots, crew and passengers from downed aircraft in search and rescue, air-sea rescue missions. The boats would race out to a crash site and rescue wounded aircrew. Some speed boats built before the war were acquired and converted to be crash boats and many new boats were built. Standard crash boats were built in four lengths for World War II. The smallest standard size boat was 42 feet long. The larger boats were 63 or 85 or 104 feet long. They were built for the Army Air Forces, US Navy and some were transferred to Allies. The design was similar to patrol boats built for the war, but with less or no armament and first aid equipped. The boats were designed to be light and fast to be able to get to the downed aircrew as fast as possible. Most were used in the Pacific war across the vast South Pacific, in the Island hopping campaign. Some were station on the West Coast of the United States to support the vast training centers. Many were designated Air Rescue Boats or ARB or AVR or P or C or R Hull classification symbol. After the war most were abandoned or destroyed, a few served in the Korean war (with United States Air Force ), some sold to private and some donated to Sea Scouts.
  • 6.2K
  • 23 Nov 2022
Topic Review
2020 Twitter Bitcoin Scam
User:RMCD bot/subject notice On July 15, 2020, between 20:00 and 22:00 UTC, around 130 high-profile Twitter accounts were compromised by outside parties to promote a bitcoin scam. Twitter and other media sources confirmed that the perpetrators had gained access to Twitter's administrative tools so that they could alter the accounts themselves and post the tweets directly. They appeared to have used social engineering to gain access to the tools via Twitter employees. The scam tweets asked individuals to send bitcoin currency to a specific cryptocurrency wallet, with the promise of the Twitter user that money sent would be doubled and returned as a charitable gesture. Within minutes from the initial tweets, more than 320 transactions had already taken place on one of the wallet addresses, and more than US$110,000 of equivalent bitcoin had been deposited in one account before the scam messages were removed by Twitter. In addition, full message history data from eight non-verified accounts was also acquired. Dmitri Alperovitch, the co-founder of cybersecurity company CrowdStrike, described the incident as "the worst hack of a major social media platform yet." The FBI and other law enforcement agencies are investigating the scam and the security used by Twitter. Security researchers expressed concerns that the social engineering used to execute the hack can affect the use of social media in important online discussions, including the lead-up into the 2020 United States presidential election.
  • 6.2K
  • 17 Nov 2022
Topic Review
Entrepreneurial Self-Efficacy
Sustaining youths interest in entrepreneurial education is important to cultivating future entrepreneurs. In entrepreneurial education, both perceived educator competency and perceived social support are important drivers for the creation of self-efficacy in youth.
  • 6.2K
  • 07 May 2022
Topic Review
Clinical Psychology
Clinical psychology is an integration of science, theory, and clinical knowledge for the purpose of understanding, preventing, and relieving psychologically-based distress or dysfunction and to promote subjective well-being and personal development. Central to its practice are psychological assessment, clinical formulation, and psychotherapy, although clinical psychologists also engage in research, teaching, consultation, forensic testimony, and program development and administration. In many countries, clinical psychology is a regulated mental health profession. The field is generally considered to have begun in 1896 with the opening of the first psychological clinic at the University of Pennsylvania by Lightner Witmer. In the first half of the 20th century, clinical psychology was focused on psychological assessment, with little attention given to treatment. This changed after the 1940s when World War II resulted in the need for a large increase in the number of trained clinicians. Since that time, three main educational models have developed in the USA—the Ph.D. Clinical Science model (heavily focused on research), the Ph.D. science-practitioner model (integrating scientific research and practice), and the Psy.D. practitioner-scholar model (focusing on clinical theory and practice). In the UK and the Republic of Ireland, the Clinical Psychology Doctorate falls between the latter two of these models, whilst in much of mainland Europe, the training is at the masters level and predominantly psychotherapeutic. Clinical psychologists are expert in providing psychotherapy, and generally train within four primary theoretical orientations—psychodynamic, humanistic, cognitive behavioral therapy (CBT), and systems or family therapy. Clinical psychology is distinguished from psychiatry. Although practitioners in both fields are mental health professionals, clinical psychologists treat mental disorders through talk therapy and have a doctorate in Psychology or a Doctor of Psychology degree but cannot prescribe medicine. Psychiatrists are medical doctors who treat mental disorders through medication and have a medical degree. Five states, Louisiana, New Mexico, Illinois, Iowa, and Idaho, allow clinical psychologists to prescribe certain medications with completion of medical training, whereas most states only allow psychiatrists to prescribe medicine.
  • 6.2K
  • 01 Nov 2022
Topic Review
Deforestation and Global Warming
Deforestation is a primary contributor to climate change. Land use changes, especially in the form of deforestation, are the second largest anthropogenic source of atmospheric carbon dioxide emissions, after fossil fuel combustion. Greenhouse gases are emitted during combustion of forest biomass and decomposition of remaining plant material and soil carbon. Global models and national greenhouse gas inventories give similar results for deforestation emissions. Although deforestation and peatland degradation are only about 10% of global carbon dioxide emissions (As of 2019), growing forests are also a carbon sink with additional potential to mitigate the effects of climate change. Some of the effects of climate change, such as more wildfires, may increase deforestation. Deforestation comes in many forms: wildfire, agricultural clearcutting, livestock ranching, and logging for timber, among others. The vast majority of agricultural activity resulting in deforestation is subsidized by government tax revenue. Forests cover 31% of the land area on Earth and annually 75,700 square kilometers (18.7 million acres) of the forest is lost. Mass deforestation continues to threaten tropical forests, their biodiversity and the ecosystem services they provide. The main area of concern of deforestation is in tropical rain forests since they are home to the majority of the planet's biodiversity.
  • 6.2K
  • 29 Nov 2022
Topic Review
Polycaprolactone-Based Biocomposites
The developments within the topic of biomaterials has taken hold of researchers due to the mounting concern of current environmental pollution as well as scarcity resources. Amongst all compatible biomaterials, polycaprolactone (PCL) is deemed to be a great potential biomaterial, especially to the tissue engineering sector, due to its advantages, including its biocompatibility and low bioactivity exhibition. The commercialization of PCL is deemed as infant technology despite of all its advantages. This contributed to the disadvantages of PCL, including expensive, toxic, and complex.
  • 6.1K
  • 10 Feb 2022
Topic Review Peer Reviewed
Serum Albumin
Being one of the most abundant proteins in human and other mammals, albumin plays a crucial role in transporting various endogenous and exogenous molecules and maintaining of colloid osmotic pressure of the blood. It is not only the passive but also the active participant of the pharmacokinetic and toxicokinetic processes possessing a number of enzymatic activities. A free thiol group of the albumin molecule determines the participation of the protein in redox reactions. Its activity is not limited to interaction with other molecules entering the blood: of great physiological importance is its interaction with the cells of blood, blood vessels and also outside the vascular bed. This topic review contains data on the enzymatic, inflammatory and antioxidant properties of serum albumin. 
  • 6.1K
  • 13 Apr 2022
Topic Review
Homosexuality
Homosexuality is romantic attraction, sexual attraction, or sexual behavior between members of the same sex or gender. As a sexual orientation, homosexuality is "an enduring pattern of emotional, romantic, and/or sexual attractions" to people of the same sex. It "also refers to a person's sense of identity based on those attractions, related behaviors, and membership in a community of others who share those attractions." Along with bisexuality and heterosexuality, homosexuality is one of the three main categories of sexual orientation within the heterosexual–homosexual continuum. Scientists do not yet know the exact cause of sexual orientation, but they theorize that it is caused by a complex interplay of genetic, hormonal, and environmental influences and do not view it as a choice. Although no single theory on the cause of sexual orientation has yet gained widespread support, scientists favor biologically-based theories. There is considerably more evidence supporting nonsocial, biological causes of sexual orientation than social ones, especially for males. There is no substantive evidence which suggests parenting or early childhood experiences play a role with regard to sexual orientation. While some people believe that homosexual activity is unnatural, scientific research shows that homosexuality is a normal and natural variation in human sexuality and is not in and of itself a source of negative psychological effects. There is insufficient evidence to support the use of psychological interventions to change sexual orientation. The most common adjectives for homosexual people are lesbian for females and gay for males, but the term gay also commonly refers to both homosexual females and males. The percentage of people who are gay or lesbian and the proportion of people who are in same-sex romantic relationships or have had same-sex sexual experiences are difficult for researchers to estimate reliably for a variety of reasons, including many gay and lesbian people not openly identifying as such due to prejudice or discrimination such as homophobia and heterosexism. Homosexual behavior has also been documented in many non-human animal species, though homosexual orientation is not significantly observed in other animals. Many gay and lesbian people are in committed same-sex relationships. These relationships are equivalent to heterosexual relationships in essential psychological respects. Homosexual relationships and acts have been admired, as well as condemned, throughout recorded history, depending on the form they took and the culture in which they occurred. Since the end of the 20th century, there has been a global movement towards freedom and equality for gay people, including the introduction of anti-bullying legislation to protect gay children at school, legislation ensuring non-discrimination, equal ability to serve in the military, equal access to health care, equal ability to adopt and parent, and the establishment of marriage equality.
  • 6.1K
  • 04 Nov 2022
Topic Review
Structure-Based Approach in Drug Design
Structure-based drug design (SBDD) is the computational approach that relies on knowledge of 3D structures of the biological targets to identify or design the potential chemical structure suitable for clinical tests. With the explosion of genomic, functional, and structural information in recent decades, the majority of biological targets with 3D structure have been identified and stimulated the applications of structure-based approaches in the current design pipeline. SBDD is popular for virtual screening to filter the drug-like compounds from a large library of small molecules, including widely applied approaches, such as docking and structure-based pharmacophore design. 
  • 6.1K
  • 24 Jan 2022
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