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Topic Review
Genetics Matters
The understanding of how genetic information may be inherited through generations was established by Gregor Mendel in the 1860s when he developed the fundamental principles of inheritance. The science of genetics, however, began to flourish only during the mid-1940s when DNA was identified as the carrier of genetic information. The world has since then witnessed rapid development of genetic technologies, with the latest being genome-editing tools, which have revolutionized fields from medicine to agriculture. This entry walks through the historical timeline of genetics research and deliberates how this discipline might furnish a sustainable future for humanity.
  • 1.5K
  • 19 Apr 2022
Topic Review
Effects of Palmitoylethanolamide on Neurodegenerative Diseases
Palmitoylethanolamide (PEA) stands out among endogenous lipid mediators for its neuroprotective, anti-inflammatory, and analgesic functions. PEA belonging to the N-acetylanolamine class of phospholipids was first isolated from soy lecithin, egg yolk, and peanut flour. It is currently used for the treatment of different types of neuropathic pain, such as fibromyalgia, osteoarthritis, carpal tunnel syndrome, and many other conditions. 
  • 1.5K
  • 19 May 2022
Topic Review
Worldwide Flor Yeasts Screening Conception for Sherry Wines
The manufacturing of sherry wines is a unique, carefully regulated process, from harvesting to quality control of the finished product, involving dynamic biological aging in a “criadera-solera” system or some other techniques. Specialized “flor” strains of the yeast Saccharomyces cerevisiae play the central role in the sherry manufacturing process. As a result, sherry wines have a characteristic and unique chemical composition that determines their organoleptic properties (such as color, odor, and taste) and distinguishes them from all other types of wine.
  • 1.5K
  • 06 Sep 2022
Topic Review
Music Generation of Traditional Chinese Pentatonic Scale
Recent studies demonstrate that algorithmic music attracted global attention not only because of its amusement but also its considerable potential in the industry. Thus, the yield increased academic numbers spinning around on topics of algorithm music generation. The balance between mathematical logic and aesthetic value is important in music generation.
  • 1.5K
  • 19 Oct 2022
Topic Review
Perfectionism
In ethics and value theory, perfectionism is the persistence of will in obtaining the optimal quality of spiritual, mental, physical, and material being. The neo-Aristotelean Thomas Hurka describes perfectionism as follows: The perfectionist does not necessarily believe that one can attain a perfect life or state of living. Rather, a perfectionist practices steadfast perseverance in obtaining the best possible life or state of living.
  • 1.5K
  • 13 Oct 2022
Topic Review
Bond Strength Deterioration Due to Corrosion
Corrosion of the reinforcement affects more than the cross-sectional area of the rebar. The volume of steel also increases due to expansive corrosion products, leading to the cracking, delamination, and spalling of concrete. As a result, the bond capacity between concrete and rebar is affected. Researchers have extensively examined the impact of corrosion on the bond strength between concrete and rebar to propose empirical, theoretical, or numerical predictive models.
  • 1.5K
  • 08 Nov 2022
Topic Review
Teapot
A teapot is a vessel used for steeping tea leaves or a herbal mix in boiling or near-boiling water, and for serving the resulting infusion which is called tea. Dry tea is available either in tea bags or as loose tea, in which case a tea infuser or tea strainer may be of some assistance, either to hold the leaves as they steep or to catch the leaves inside the teapot when the tea is poured. Teapots usually have an opening with a lid at their top, where the dry tea and hot water are added, a handle for holding by hand and a spout through which the tea is served. Some teapots have a strainer built-in on the inner edge of the spout. A small air hole in the lid is often created to stop the spout from dripping and splashing when tea is poured. In modern times, a thermal cover called a tea cosy may be used to enhance the steeping process or to prevent the contents of the teapot from cooling too rapidly.
  • 1.5K
  • 10 Nov 2022
Topic Review
The Structure of Carbon Dots
Carbon allotropes are multifunctional materials, due to their unique physical and chemical properties. Carbon allotropes can be chemically modified by other elements via functionalization or doping, and they can also be used in combination with other materials to form carbon–carbon or metal–carbon composite materials.
  • 1.5K
  • 21 Aug 2023
Topic Review
Transformer-Based Model for Predicting Customers’ NPD in e-Commerce
Transformers offer advantages in capturing long-term dependencies within time series data through self-attention mechanisms. This adaptability to various time series patterns, including trends, seasonality, and irregularities, makes them a promising choice for next purchase day (NPD) prediction. The transformer model demonstrates improvements in prediction accuracy compared to the baselines. 
  • 1.5K
  • 02 Nov 2023
Topic Review
Recyclable Design of Wooden Furniture
With the rapid development of the economy and the change in people’s aesthetic concepts, the renewal of furniture has become more and more frequent. Among the huge amount of used furniture, solid wood and wood-based panel furniture account for the vast majority, but the imperfective recycling system and insufficient recycling efforts result in serious waste, which is contrary to the low-carbon transition and sustainable development means. 
  • 1.5K
  • 21 Dec 2023
Topic Review
Gel Foam Extinguishing Agent in Coal Mines
Coal is a fossil fuel with great economic potential, but meanwhile, it is threatened by coal spontaneous combustion during coal production. Gel foam extinguishing agent (gel foam) has promising applications in the prevention and management of mine coal spontaneous combustion.
  • 1.5K
  • 02 Jan 2024
Topic Review
May 24: Samuel Morse Sends the First Telegraph Message
On May 24, 1844, Samuel Finley Breese Morse (1791–1872), an American inventor and artist, transmitted the first long-distance electrical telegraph message between Washington, D.C., and Baltimore, Maryland, inaugurating a new era in electrical communication. The message, “What hath God wrought?”, was received by Alfred Vail, Morse’s collaborator, and marked the first public demonstration of the potential of the electromagnetic telegraph system.
  • 1.5K
  • 22 May 2025
Topic Review
High-resolution melt method
HRM (High-resolution melt) analysis is a powerful molecular biology detection method used for the identification of genetic mutations, DNA methylation analysis or species identification. 
  • 1.5K
  • 27 Oct 2020
Topic Review
Corporate Sustainability in Bangladeshi Banks
       The purpose of this study is to analyze the connection between the sustainability performance and financial performance of Bangladeshi banks to explore the impact of the Bangladesh Environmental Risk Management Guideline. We analyzed all 56 scheduled commercial banks that are currently operating in Bangladesh under the guidelines of the Central Bank of Bangladesh. Data for the sample has been collected from publicly available reports such as annual, sustainability, and corporate social responsibility (CSR) reports, disclosed sustainability and financial information on the banks’ websites, including all bank branches, and data published from the Central Bank. Data has been analyzed using panel regression. Our results indicate that higher sustainability performance creates a higher financial performance, and that bigger banks perform better with regard to sustainability than smaller banks. The analysis did not find, however, that higher financial performance influences the sustainability performance of the banks positively. Consequently, this research contributes to the research on legitimacy-driven behavior of Bangladeshi banks. This behavior rather leads to a reactive adoption of sustainability activities instead of proactive behavior.
  • 1.5K
  • 13 Oct 2020
Topic Review
Schizophrenia
Schizophrenia is a brain disorder classified as a psychosis, which means that it affects a person's thinking, sense of self, and perceptions. The disorder typically becomes evident during late adolescence or early adulthood.
  • 1.5K
  • 04 Jan 2021
Topic Review
Optoacoustic Imaging
Optoacoustic or photoacoustic imaging (OAI/PAI) has the unique ability and scalability to visualize, monitor, and understand the molecular mechanisms of inflammation.
  • 1.5K
  • 20 May 2021
Topic Review
Selenium Nanoparticles in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a common chronic inflammation-mediated disorder having systematic complications. RA triggers a self-directed inflammatory and immunological cascade that culminates in joint destruction. Though a range of treatment options are available, none of them are without adverse effects, leading researchers to search for alternative solutions. Nanomedicine has emerged as a powerful therapeutic alternative, and selenium (Se) is an essential micronutrient trace element that has a crucial role in human health and disease.  The potential of SeNPs can be attributed to the effect of functional groups bound to them, concentration, and most importantly to their nano range size. The antirheumatic effect of SeNPs is considerable due to its potential in amelioration of oxidative stress-mediated inflammation via downregulation of radical and nonradical species, markers of inflammation, and upregulation of inherent antioxidant defenses.
  • 1.5K
  • 16 Aug 2021
Topic Review
5-Hydroxytryptamine and Gut
Serotonin, also known as 5-hydroxytryptamine (5-HT), is a metabolite of tryptophan and is reported to modulate the development and neurogenesis of the enteric nervous system, gut motility, secretion, inflammation, sensation, and epithelial development. Approximately 95% of 5-HT in the body is synthesized and secreted by enterochromaffin (EC) cells, the most common type of neuroendocrine cells in the gastrointestinal (GI) tract, through sensing signals from the intestinal lumen and the circulatory system. Gut microbiota, nutrients, and hormones are the main factors that play a vital role in regulating 5-HT secretion by EC cells. Apart from being an important neurotransmitter and a paracrine signaling molecule in the gut, gut-derived 5-HT was also shown to exert other biological functions (in autism and depression) far beyond the gut. Moreover, studies conducted on the regulation of 5-HT in the immune system demonstrated that 5-HT exerts anti-inflammatory and proinflammatory effects on the gut by binding to different receptors under intestinal inflammatory conditions. Understanding the regulatory mechanisms through which 5-HT participates in cell metabolism and physiology can provide potential therapeutic strategies for treating intestinal diseases. Herein, we review recent evidence to recapitulate the mechanisms of synthesis, secretion, regulation, and biofunction of 5-HT to improve the nutrition and health of humans.
  • 1.5K
  • 17 Aug 2021
Topic Review
Antibacterial Properties of Diverse Cellulose-Based Hydrogels
Pathogens, especially drug-resistant pathogens caused by the abuse of antibiotics, have become a major threat to human health and public health safety. The exploitation and application of new antibacterial agents is extremely urgent. As a natural biopolymer, cellulose has recently attracted much attention due to its excellent hydrophilicity, economy, biocompatibility, and biodegradability. In particular, the preparation of cellulose-based hydrogels with excellent structure and properties from cellulose and its derivatives has received increasing attention thanks to the existence of abundant hydrophilic functional groups (such as hydroxyl, carboxy, and aldehyde groups) within cellulose and its derivatives. The cellulose-based hydrogels have broad application prospects in antibacterial-related biomedical fields. 
  • 1.5K
  • 21 Mar 2022
Topic Review
Intramedullary Spinal Cord Abscess among Children
Intramedullary spinal cord abscesses (ISCA) are rare. Typical symptoms include signs of infection and neurological deficits. Symptoms among (younger) children can be highly uncharacteristic. Therefore, prompt and proper diagnoses may be difficult. Typical therapeutic options include antibiotics and neurosurgical exploration and drainage.
  • 1.5K
  • 09 Aug 2022
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