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Tang, P. Schizophrenia. Encyclopedia. Available online: https://encyclopedia.pub/entry/5987 (accessed on 20 September 2026).
Tang P. Schizophrenia. Encyclopedia. Available at: https://encyclopedia.pub/entry/5987. Accessed September 20, 2026.
Tang, Peter. "Schizophrenia" Encyclopedia, https://encyclopedia.pub/entry/5987 (accessed September 20, 2026).
Tang, P. (2021, January 04). Schizophrenia. In Encyclopedia. https://encyclopedia.pub/entry/5987
Tang, Peter. "Schizophrenia." Encyclopedia. Web. 04 January, 2021.
Schizophrenia
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/schizophrenia

Schizophrenia is a brain disorder classified as a psychosis, which means that it affects a person's thinking, sense of self, and perceptions. The disorder typically becomes evident during late adolescence or early adulthood.

genetic conditions

References

  1. Barker V, Bois C, Johnstone EC, Owens DG, Whalley HC, McIntosh AM, Lawrie SM. Childhood adversity and cortical thickness and surface area in a population atfamilial high risk of schizophrenia. Psychol Med. 2016 Mar;46(4):891-6. doi:10.1017/S0033291715002585. Epub 2015 Dec 14. Citation on PubMed
  2. Debost JP, Larsen JT, Munk-Olsen T, Mortensen PB, Meyer U, Petersen L. JointEffects of Exposure to Prenatal Infection and Peripubertal Psychological Traumain Schizophrenia. Schizophr Bull. 2017 Jan;43(1):171-179. doi:10.1093/schbul/sbw083. Epub 2016 Jun 24. Citation on PubMed
  3. Escudero I, Johnstone M. Genetics of schizophrenia. Curr Psychiatry Rep. 2014 Nov;16(11):502. doi: 10.1007/s11920-014-0502-8. Review. Citation on PubMed
  4. Farrell MS, Werge T, Sklar P, Owen MJ, Ophoff RA, O'Donovan MC, Corvin A,Cichon S, Sullivan PF. Evaluating historical candidate genes for schizophrenia.Mol Psychiatry. 2015 May;20(5):555-62. doi: 10.1038/mp.2015.16. Epub 2015 Mar 10.Review. Citation on PubMed or Free article on PubMed Central
  5. Giusti-Rodríguez P, Sullivan PF. The genomics of schizophrenia: update andimplications. J Clin Invest. 2013 Nov;123(11):4557-63. doi: 10.1172/JCI66031.Epub 2013 Nov 1. Review. Citation on PubMed or Free article on PubMed Central
  6. Gulsuner S, Walsh T, Watts AC, Lee MK, Thornton AM, Casadei S, Rippey C,Shahin H; Consortium on the Genetics of Schizophrenia (COGS); PAARTNERS StudyGroup, Nimgaonkar VL, Go RC, Savage RM, Swerdlow NR, Gur RE, Braff DL, King MC,McClellan JM. Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network. Cell. 2013 Aug 1;154(3):518-29. doi:10.1016/j.cell.2013.06.049. Citation on PubMed or Free article on PubMed Central
  7. Kavanagh DH, Tansey KE, O'Donovan MC, Owen MJ. Schizophrenia genetics:emerging themes for a complex disorder. Mol Psychiatry. 2015 Feb;20(1):72-6. doi:10.1038/mp.2014.148. Epub 2014 Nov 11. Citation on PubMed
  8. Purcell SM, Moran JL, Fromer M, Ruderfer D, Solovieff N, Roussos P,O'Dushlaine C, Chambert K, Bergen SE, Kähler A, Duncan L, Stahl E, Genovese G,Fernández E, Collins MO, Komiyama NH, Choudhary JS, Magnusson PK, Banks E, ShakirK, Garimella K, Fennell T, DePristo M, Grant SG, Haggarty SJ, Gabriel S, ScolnickEM, Lander ES, Hultman CM, Sullivan PF, McCarroll SA, Sklar P. A polygenic burdenof rare disruptive mutations in schizophrenia. Nature. 2014 Feb13;506(7487):185-90. doi: 10.1038/nature12975. Epub 2014 Jan 22. Citation on PubMed or Free article on PubMed Central
  9. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Biologicalinsights from 108 schizophrenia-associated genetic loci. Nature. 2014 Jul24;511(7510):421-7. doi: 10.1038/nature13595. Epub 2014 Jul 22. Citation on PubMed or Free article on PubMed Central
  10. Sekar A, Bialas AR, de Rivera H, Davis A, Hammond TR, Kamitaki N, Tooley K,Presumey J, Baum M, Van Doren V, Genovese G, Rose SA, Handsaker RE; SchizophreniaWorking Group of the Psychiatric Genomics Consortium, Daly MJ, Carroll MC,Stevens B, McCarroll SA. Schizophrenia risk from complex variation of complement component 4. Nature. 2016 Feb 11;530(7589):177-83. doi: 10.1038/nature16549. Epub2016 Jan 27. Citation on PubMed or Free article on PubMed Central
  11. Sullivan PF, Daly MJ, O'Donovan M. Genetic architectures of psychiatricdisorders: the emerging picture and its implications. Nat Rev Genet. 2012 Jul10;13(8):537-51. doi: 10.1038/nrg3240. Review. Citation on PubMed or Free article on PubMed Central
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Subjects: Genetics & Heredity
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Update Date: 04 Jan 2021
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