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Topic Review
Carbon fiber-reinforced Thermoplastic polymers
Carbon fiber-reinforced thermoplastic polymers are considered a promising composite for many industrial applications including in the automation, renewable energy, and aerospace industries. They exhibit exceptional properties such as a high strength-to-weight ratio and high wear resistance and stiffness, which give them an advantage over other conventional materials such as metals.
  • 6.7K
  • 17 Aug 2021
Topic Review
Perinatal Stem Cells
Perinatal tissues refer to tissues that are discarded at birth, such as the placenta, umbilical cord, cord blood, and amniotic fluid, and different stem and progenitor cell types can be isolated from these tissues. Regenerative medicine has found in the perinatal medical wastes one of the most promising sources of various cells and tissues for use in cell therapy and tissue engineering, both in experimental and clinical settings. The primary source of perinatal stem cells is cord blood. Cord blood has been a well-known source of hematopoietic stem/progenitor cells. Other perinatal tissues contain non-hematopoietic cells with potential therapeutic value. Indeed, in advanced perinatal cell therapy trials, mesenchymal stromal cells are the most commonly used.
  • 6.7K
  • 14 Jan 2021
Topic Review
Fresh Fruit and Vegetable Waste in Human Health
Food supply disruption and shortage verified during the current pandemic events are a scenario that many anticipate for the near future. The impact of climate changes on food production, the continuous decrease in arable land, and the exponential growth of the human population are important drivers for this problem. 
  • 6.7K
  • 19 Jan 2023
Topic Review
Superior Orders
Superior orders, also known as the Nuremberg defense or just following orders, is a plea in a court of law that a person, whether a member of the military, law enforcement, a firefighting force, or the civilian population, should not be considered guilty of committing actions that were ordered by a superior officer or official. The superior orders plea is often regarded as the complement to command responsibility. One of the most noted uses of this plea, or defense, was by the accused in the 1945–1946 Nuremberg trials, such that it is also called the "Nuremberg defense". The Nuremberg trials were a series of military tribunals, held by the main victorious Allies after World War II, most notable for the prosecution of prominent members of the political, military, and economic leadership of the defeated Nazi Germany. These trials, under the London Charter of the International Military Tribunal that established them, determined that the defense of superior orders was no longer enough to escape punishment, but merely enough to lessen punishment. Historically, the plea of superior orders has been used both before and after the Nuremberg Trials, with inconsistent rulings. Apart from the specific plea of superior orders, discussions about how the general concept of superior orders ought to be used, or ought not to be used, have taken place in various arguments, rulings and statutes that have not necessarily been part of "after the fact" war crimes trials, strictly speaking. Nevertheless, these discussions and related events help to explain the evolution of the specific plea of superior orders and the history of its usage.
  • 6.7K
  • 08 Nov 2022
Topic Review Peer Reviewed
Domestic Environmental Experience Design
The term 'domestic environmental experience' was defined as users' experiences of cognitive perceptions and physical responses to their domestic built environments. Domestic environments can be enriched through the implementation of environmental experience design (EXD) by combining users' environmental, spatial and contextual factors that may accommodate occupants' needs and demands as well as their health and wellbeing. Here, an EXD theoretical concept has been developed based on the 'User-Centred Design' thematical framework.
  • 6.7K
  • 13 Apr 2022
Topic Review
Palmitoylethanolamide in Autism Spectrum Disorder
Palmitoylethanolamide (PEA) is a naturally occurring saturated N-acylethanolamine that has proven to be effective in controlling inflammation, depression, epilepsy, and pain, possibly through a neuroprotective role against glutamate toxicity. Here, we systematically reviewed all human and animal studies examining PEA and its biobehavioral correlates in ASD. Studies indicate altered serum/brain levels of PEA and other endocannabinoids (ECBs)/acylethanolamines (AEs) in ASD. Altered PEA signaling response to social exposure and altered expression/activity of enzymes responsible for the synthesis and catalysis of ECBs/AEs, as well as downregulation of the peroxisome proliferator activated receptor-α (PPAR-α) and cannabinoid receptor target GPR55 mRNA brain expression, have been reported. Stress and exposure to exogenous cannabinoids may modulate ECBs/AEs levels and expression of candidate genes for neuropsychiatric disorders, with implications for ASD. Limited research suggests that PEA supplementation reduces overall autism severity by improving language and social and nonsocial behaviors. Potential neurobiological underpinnings include modulation of immune response, neuroinflammation, neurotrophy, apoptosis, neurogenesis, neuroplasticity, neurodegeneration, mitochondrial function, and microbiota activity, possibly through peroxisome proliferator-activated receptor-α (PPAR-α) activation.
  • 6.7K
  • 08 Sep 2021
Topic Review
Kairos
Kairos (καιρός) is an Ancient Greek word meaning the right, critical, or opportune moment. The ancient Greeks had two words for time: chronos (χρόνος) and kairos. The former refers to chronological or sequential time, while the latter signifies a proper or opportune time for action. While chronos is quantitative, kairos has a qualitative, permanent nature. Kairos also means weather in Modern Greek. The plural, καιροί (kairoi (Ancient and Modern Greek)) means the times. Kairos is a term, idea, and practice that has been applied in several fields including classical rhetoric, modern rhetoric, digital media, Christian theology, and science.
  • 6.7K
  • 07 Oct 2022
Topic Review
Bṛhaspati
Bṛhaspati (Sanskrit: बृहस्पति; meaning spati of briha, the spirit of vastness of the universe written as Brihaspati) is an Indian name, and refers to different mythical figures depending on the age of the text. In ancient Hindu literature Brihaspati is a Vedic era sage who counsels the gods, while in some medieval texts the word refers to the largest planet of the solar system, Jupiter. He taught Bhishma the duties of a king which he later taught it to Vidura.
  • 6.7K
  • 18 Oct 2022
Topic Review
Glossary of Bird Terms
The following is a glossary of common English language terms used in the description of birds—warm-blooded vertebrates of the class Aves and the only living dinosaurs, characterized by feathers, the ability to fly in all but the approximately 60 extant species of flightless birds, toothless, beaked jaws, the laying of hard-shelled eggs, a high metabolic rate, a four-chambered heart and a strong yet lightweight skeleton. Among other details such as size, proportions and shape, terms defining bird features developed and are used to describe features unique to the class—especially evolutionary adaptations that developed to aid flight. There are, for example, numerous terms describing the complex structural makeup of feathers (e.g., barbules, rachides and vanes); types of feathers (e.g., filoplume, pennaceous and plumulaceous feathers); and their growth and loss (e.g., colour morph, nuptial plumage and pterylosis). There are thousands of terms that are unique to the study of birds. This glossary makes no attempt to cover them all, concentrating on terms that might be found across descriptions of multiple bird species by bird enthusiasts and ornithologists. Though words that are not unique to birds are also covered, such as "back" or "belly", they are defined in relation to other unique features of external bird anatomy, sometimes called "topography". As a rule, this glossary does not contain individual entries on any of the approximately 9,700 recognized living individual bird species of the world.
  • 6.7K
  • 09 Nov 2022
Topic Review
The Subretinal Space of the Eye
The subretinal space is located between the retinal pigment epithelium (RPE) and the photoreceptive cells. The majority of the retina is a delicate matrix of photoreceptive cells and their support network which are responsible for human vision. These cells are separated from the choroid by a layer of pigment epithelium. The RPE has tight junctions, effectively insulating the inside of the retina from systemic circulation; the contents of the retina can then be controlled by transcellular transport.
  • 6.7K
  • 03 May 2025
Topic Review
Toxicity of Titanium Compounds
Titanium and its compounds are broadly used in both industrial and domestic products, including jet engines, missiles, prostheses, implants, pigments, cosmetics, food, and photocatalysts for environmental purification and solar energy conversion. Although titanium/titania-containing materials are usually safe for human, animals and environment, increasing concerns on their negative impacts have been postulated. We have reported the state of knowledge about toxicity of titanium, its alloys and oxides. Due to the alarming increase in titania/titanium applications in various daily care products and medical treatment (e.g. dental implants) the possible toxicity and environmental impact should be considered.  The collected data might allow to identify some harms associated with using of titania and titanium compounds.
  • 6.7K
  • 21 Feb 2021
Topic Review
Pet Husbandry
Pet husbandry is the practices applied in day-to-day care of animal companions, which can greatly impact animal welfare. Pet husbandry include: (1) origin of pets; (2) number and type of pets in the household; (3) diet type and feeding practices; (4) living environment and daily activities; (5) preventive treatment for parasites and vaccination; (6) regular veterinary check-ups and access to health care; and (7) compliance with legal requirements and identification.
  • 6.7K
  • 29 Oct 2020
Topic Review
Overcurrent Relays and Their Usage
Overcurrent relays (OCR) are used as the main protection device due to their lower cost compared to other types of relays. Overcurrent relays can be divided roughly into two types, judging by their time–current characteristic: definite-time OCRs and inverse-time OCRs.
  • 6.7K
  • 18 Feb 2022
Topic Review
Lipid-Based Nanoparticles
COVID-19 vaccines have been developed with unprecedented speed which would not have been possible without decades of fundamental research on delivery nanotechnology. Lipid-based nanoparticles have played a pivotal role in the successes of COVID-19 vaccines and many other nanomedicines, such as Doxil® and Onpattro®, and have therefore been considered as the frontrunner in nanoscale drug delivery systems. In this review, we aim to highlight the progress in the development of these lipid nanoparticles for various applications, ranging from cancer nanomedicines to COVID-19 vaccines. The lipid-based nanoparticles discussed in this review are liposomes, niosomes, transfersomes, solid lipid nanoparticles, and nanostructured lipid carriers. We particularly focus on the innovations that have obtained regulatory approval or that are in clinical trials. We also discuss the physicochemical properties required for specific applications, highlight the differences in requirements for the delivery of different cargos, and introduce current challenges that need further development. This review serves as a useful guideline for designing new lipid nanoparticles for both preventative and therapeutic vaccines including immunotherapies.
  • 6.6K
  • 19 May 2021
Topic Review
Pyrido[2,3-d], [3,2-d], [3,4-d] and [4,3-d]pyrimidine Derivatives
The structures composed of a pyridopyrimidine moiety which have shown a therapeutic interest or have already been approved for use as therapeutics, including pyrido[2,3-d]pyrimidines, pyrido[3,4-d]pyrimidines, pyrido[4,3-d]pyrimidines and pyrido[3,2-d]pyrimidines.
  • 6.6K
  • 06 Apr 2022
Topic Review
Frequency
Frequency is the number of occurrences of a repeating event per unit of time. It is also referred to as temporal frequency, which emphasizes the contrast to spatial frequency and angular frequency. Frequency is measured in units of hertz (Hz) which is equal to one occurrence of a repeating event per second. The period is the duration of time of one cycle in a repeating event, so the period is the reciprocal of the frequency. For example: if a newborn baby's heart beats at a frequency of 120 times a minute (2 hertz), its period, T, — the time interval between beats—is half a second (60 seconds divided by 120 beats). Frequency is an important parameter used in science and engineering to specify the rate of oscillatory and vibratory phenomena, such as mechanical vibrations, audio signals (sound), radio waves, and light.
  • 6.6K
  • 16 Nov 2022
Topic Review
Triangulation Station
A triangulation station, also known as a triangulation pillar, trigonometrical station, trigonometrical point, trig station, trig beacon, or trig point, and sometimes informally as a trig, is a fixed surveying station, used in geodetic surveying and other surveying projects in its vicinity. The nomenclature varies regionally: they are generally known as trigonometrical or triangulation stations in North America, trig points in the United Kingdom, trig pillars in Ireland, trig stations or points in Australia and New Zealand, and trig beacons in South Africa; triangulation pillar is the more formal term for the concrete columns found in the UK.
  • 6.6K
  • 02 Dec 2022
Topic Review
Muesli
Muesli (/ˈmjuːzli/ MEWZ-lee; Template:Lang-gsw Template:IPA-gsw, non-Swiss Standard German: Müsli [ˈmyːsli] (listen)) is a cold oatmeal dish based on rolled oats and ingredients like grains, nuts, seeds and fresh or dried fruits. This mix may be combined with one or more liquids like milk, almond milk, other plant milks, yogurt, or fruit juice and left for a time to soften the oats before being consumed. Developed around 1900 by Swiss physician Maximilian Bircher-Benner for patients in his hospital, it is now eaten as a standard breakfast dish, and also in Switzerland as a supper called Birchermüesli complet: muesli with Café complet (milk coffee, accompanied with bread, butter, and jam. (Butterbrot)).
  • 6.6K
  • 15 Nov 2022
Topic Review
Emgrand EC7
The Geely Emgrand or originally, the Emgrand EC7 is a compact car produced by the Emgrand division of the Chinese automaker Geely. After the discontinuation of the "Emgrand" brand, Emgrand EC7 was renamed to Geely Emgrand in 2014. The second generation Geely Emgrand was shown to public in 2014 Beijing Auto Show.
  • 6.6K
  • 23 Nov 2022
Topic Review
Glass–Ceramics
Owing to their combinations of unique properties of sintered ceramics and the distinctive characteristics of glasses, glass-ceramics have attracted great interest from both academia and industry worldwide since their accidental discovery in 1953.
  • 6.6K
  • 27 Oct 2020
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