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Biography
James Hinton
James Hinton (baptized 26 November 1822 – died 16 December 1875) was an English surgeon and author. He was the father of mathematician Charles Howard Hinton. He was born at Reading, Berkshire, the son of John Howard Hinton, Baptist minister and author of the History and Topography of the United States and other works. James was educated at his grandfather's school near Oxford, and at the No
  • 1.7K
  • 12 Dec 2022
Topic Review
Forefoot Function after Hallux Valgus Surgery
The load integrals (impulse) over the central metatarsal region significantly increased, indicating that surgeries increased the risk of transfer metatarsalgia. There is no solid evidence that hallux valgus (HV) surgeries could improve forefoot functions from a biomechanical point perspective. Surgeries might reduce the plantar load over the hallux and adversely affect push-off function. 
  • 1.7K
  • 16 Feb 2023
Topic Review
Architecture of Time-Sensitive Network Configuration Management System
Many network applications are seeking to implement Time-Sensitive Network (TSN) technology, which not only furnishes communication transmission services that are deterministic, low-latency, highly dependable, and have ample bandwidth, but also enables unified configuration management, permitting different network types to function under a single management system. These characteristics enable it to be widely used in many fields such as industrial sensor and actuator networks, in-vehicle networks, data center networks, and edge computing. Nonetheless, TSN’s configuration management faces numerous difficulties and challenges related to network deployment, automated operation, and maintenance, as well as real-time and safety assurance, rendering it exceedingly intricate.
  • 1.7K
  • 13 Jul 2023
Topic Review
Stromal Proliferation in Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a chronic proliferative disease showing stromal-dominant proliferation.  Inflammation in BPH tissues by various factors finally leads to tissue remodeling and stromal proliferation through the wound healing process of the prostate. The stromal proliferation of BPH develops by two pathways, including androgen-dependent and androgen-independent pathways.
  • 1.7K
  • 04 Aug 2023
Topic Review
Preparation of Cyrene
The bio-based solvent dihydrolevoglucosenone (Cyrene) is a green and sustainable alternative to petroleum-based dipolar aprotic solvents. Cyrene can be prepared from cellulose in a simple two-step process and can be produced in a variety of yields. Cyrene is compatible with a large number of reactions in the chemical industry and can be applied in organic chemistry, biocatalysis, materials chemistry, graphene and lignin processing, etc. 
  • 1.7K
  • 25 Oct 2023
Topic Review
Green Roofs in Urban Areas
The presence of green roofs in urban areas provides various ecosystem services that help mitigate climate change. They play an essential role in sustainable drainage systems, contribute to air quality and carbon sequestration, mitigate urban heat island, support biodiversity, and create green spaces supporting public well-being. Bus stops provide good opportunities for installing green roofs. 
  • 1.7K
  • 06 Nov 2023
Topic Review Peer Reviewed
Metaverse Territorial Scale: A New Paradigm for Spatial Analysis
The Metaverse Territorial Scale is a novel category of spatial analysis, extending beyond conventional physical scales. It conceptualizes the metaverse as a distinct territory, shaped not only by geographical contiguity but also by power relations that emerge through digital interactions, code infrastructures, and platform-based governance in an immersive space undergoing continuous co-production. This concept is rooted in the theory of territory, which defines it as a space produced by the action of social actors. However, the theory is expanded to a domain where territorialization transcends physical materiality and generates new forms of territorialities. Consequently, the scale proposed is considered a valuable addition to the existing array of scales, including traditional categories such as local, regional, national, and global scales. This phenomenon differs fundamentally from geographical scales due to the absence of physical barriers, which endows it with unparalleled adaptability and scalability. This allows the overlapping of multiple spatial logics within the same virtual environment, characterized by a high degree of immersion. The “Metaverse Territorial Scale” is therefore a conceptualization of a virtual-immersive spatial dimension that is not static; it is continuously shaped and redefined by user interactions and underlying technological innovations. Consequently, analysis from the perspective of this scale is essential for understanding the spatial and power dynamics that manifest themselves in cyberspace.
  • 1.7K
  • 09 Sep 2025
Topic Review
Molecularly Imprinted Polymers in Sample Preparation
Molecularly Imprinted Polymers (MIPs) are synthetic polymeric materials with imprinted sites complementary to a specific molecule and high affinity over analytes with analogous molecular structure. Extraction can benefit from the production of MIPs that can be applied as sorbents for the extraction of specific antibiotics. 
  • 1.7K
  • 17 Jul 2023
Topic Review
Cold-Sprayed In718-Ni Composite Coating
The cold-spray technique was used to deposit Inconel 718–nickel (1:1) composite coatings on stainless steel substrate. A general full factorial design was adopted to identify the statistically significant operating variables, i.e., impingement angle, erodent size, and feed rate on the coating erosion response. Erodent feed rate, impingement angle, and the interaction between impingement angle and erodent size were identified as the highly significant variables on the erosion rate. Then, a model correlating the identified variables with the erosion rate was derived. The best combination of control variables for minimum erosion loss with respect to erodent feed rate, erodent size, and impingement angle was 2 mg/min, 60 µm, and 90°, respectively.
  • 1.7K
  • 02 Nov 2020
Topic Review
Mycobacterium Chimaera
Mycobacterium Chimaera (MC) in recent years has shown a high infectious capacity via the aerosol by operating room equipment and represent a new frontier of medico legal aspect of nosocomila infections
  • 1.7K
  • 29 Oct 2020
Topic Review
Pharmaceutical Service
Pharmaceutical services are activities of pharmacists in the healthcare system to obtain a measurable benefit, including providing access to high-quality medicinal products, subsequent rational management, as well as preventive medicine.
  • 1.7K
  • 12 Nov 2020
Topic Review
Streptococcal Infections in Marine Mammals
Marine mammals are sentinels for the marine ecosystem and threatened by numerous factors including infectious diseases. One of the most frequently isolated bacteria are beta-hemolytic streptococci. However, knowledge on ecology and epidemiology of streptococcal species in marine mammals is very limited.
  • 1.7K
  • 18 Mar 2021
Topic Review
Solid Polymer and Composite Electrolytes
All-solid-state lithium batteries (ASSLB) are very promising for the future development of next generation lithium battery systems due to their increased energy density and improved safety. ASSLB employing Solid Polymer Electrolytes (SPE) and Solid Composite Electrolytes (SCE) in particular have attracted significant attention.
  • 1.7K
  • 04 Aug 2021
Topic Review
Image-Based Crack Detection Methods
After preprocessing of images, a multiple directional non-minimum suppression (MDNMS) method is applied for crack detection. A linear SVM classifier is used to differentiate between various pavements across Spain to determine optimal parameters for crack detection. The performance of the crack detection method is improved by adapting parameters specific to the pavement.
  • 1.7K
  • 19 Aug 2021
Topic Review
Deep Learning Based Object Detection
Object detection is a complex problem due to underlying high intra-class and low inter-class variance. High intra-class variance is the consequence of different objects belonging to a single class, for instance, different poses of humans or humans wearing different clothes in an image. Low inter-class variance is the outcome of similar-looking objects belonging to different classes such as samples of class chair can easily be misclassified into the class bench and vice versa.
  • 1.7K
  • 31 Aug 2021
Topic Review
Insulin-like Growth Factor 1 Signaling in Mammalian Hearing
Insulin-like growth factor 1 (IGF-1) is a peptide hormone belonging to the insulin family of proteins. Almost all of the biological effects of IGF-1 are mediated through binding to its high-affinity tyrosine kinase receptor (IGF1R), a transmembrane receptor belonging to the insulin receptor family. Factors, receptors and IGF-binding proteins form the IGF system, which has multiple roles in mammalian development, adult tissue homeostasis, and aging. Consequently, mutations in genes of the IGF system, including downstream intracellular targets, underlie multiple common pathologies and are associated with multiple rare human diseases. Here we review the contribution of the IGF system to our understanding of the molecular and genetic basis of human hearing loss by describing, (i) the expression patterns of the IGF system in the mammalian inner ear; (ii) downstream signaling of IGF-1 in the hearing organ; (iii) mouse mutations in the IGF system, including upstream regulators and downstream targets of IGF-1 that inform cochlear pathophysiology; and (iv) human mutations in these genes causing hearing loss.
  • 1.7K
  • 22 Oct 2021
Topic Review
Furan Formation
Furan and its derivates are present in a wide range of thermally processed foods and are of significant concern in jarred baby and toddler foods. Furan formation is attributed to chemical reactions between a variety of precursors and a high processing temperature. Also, some kinetic models to represent its formation in different food materials have been studied and could predict the furan formation under simulated operating conditions.
  • 1.7K
  • 29 Oct 2021
Topic Review
Conventional Roller Compaction Method
As an empirical control method, the conventional compaction has the characteristics of manual driving, construction site supervision, manual recording, and sampling point detection. Currently, conventional compaction methods can be divided into four types: sampling point detection, prediction and simulation analysis, construction site supervision, and influencing factor analysis. In actual engineering, conventional compaction methods mainly rely on the manual control of compaction parameters (such as the number of compaction times, compaction trajectory, vibration frequency, lift thickness, and driving speed) during construction, as well as the sampling point detection (such as compactness or dry density) of specified locations after construction to ensure compaction quality of earthwork.
  • 1.7K
  • 22 Apr 2022
Topic Review
High-Altitude Wind Power
High-altitude wind power (HAWP) is the harnessing of the power of winds high in the sky by use of tether and cable technology. An atlas of the high-altitude wind power resource has been prepared for all points on Earth. A similar atlas of global assessment was developed at Joby Energy. The results were presented at the first annual Airborne Wind Energy Conference held at Stanford University by Airborne Wind Energy Consortium. Various mechanisms are proposed for capturing the kinetic energy of winds such as kites, kytoons, aerostats, gliders, gliders with turbines for regenerative soaring, sailplanes with turbines, or other airfoils, including multiple-point building- or terrain-enabled holdings. Once the mechanical energy is derived from the wind's kinetic energy, then many options are available for using that mechanical energy: direct traction, conversion to electricity aloft or at ground station, conversion to laser or microwave for power beaming to other aircraft or ground receivers. Energy generated by a high-altitude system may be used aloft or sent to the ground surface by conducting cables, mechanical force through a tether, rotation of endless line loop, movement of changed chemicals, flow of high-pressure gases, flow of low-pressure gases, or laser or microwave power beams.
  • 1.7K
  • 24 Oct 2022
Topic Review
Principle of Liquid Crystal Biosensors
Liquid crystals (LCs) are phase transition materials that exist between the liquid and the crystal states, and they can flow as liquids and also have properties such as birefringence of crystals. LCs have been widely used as sensitive elements to construct LC biosensors based on the principle that specific bonding events between biomolecules can affect the orientation of LC molecules.
  • 1.7K
  • 25 Aug 2022
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