Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Economic Impact Analysis
An economic impact analysis (EIA) examines the effect of an event on the economy in a specified area, ranging from a single neighborhood to the entire globe. It usually measures changes in business revenue, business profits, personal wages, and/or jobs. The economic event analyzed can include implementation of a new policy or project, or may simply be the presence of a business or organization. An economic impact analysis is commonly conducted when there is public concern about the potential impacts of a proposed project or policy. An economic impact analysis typically measures or estimates the change in economic activity between two scenarios, one assuming the economic event occurs, and one assuming it does not occur (which is referred to as the counterfactual case). This can be accomplished either before or after the event (ex ante or ex post). An economic impact analysis attempts to measure or estimate the change in economic activity in a specified region, caused by a specific business, organization, policy, program, project, activity, or other economic event. The study region can be a neighborhood, town, city, county, statistical area, state, country, continent, or the entire globe.
  • 1.9K
  • 18 Oct 2022
Topic Review
Building Energy Modeling Approaches
Buildings use up to 40% of the global primary energy and 30% of global greenhouse gas emissions, which may significantly impact climate change. Heating, ventilation, and air-conditioning (HVAC) systems are among the most significant contributors to global primary energy consumption and carbon gas emissions. Extensive research and advanced HVAC modeling/control techniques have emerged to provide better solutions in response to the issues.
  • 1.9K
  • 26 Oct 2022
Topic Review
Phenolic Compounds in Food Packaging
The use of phenolic-compound-based active-packaging and edible films/coatings with antimicrobial and antioxidant activities is an innovative approach that has gained widespread attention worldwide. As phenolic compounds are natural bioactive molecules that are present in a wide range of foods, such as fruits, vegetables, herbs, oils, spices, tea, chocolate, and wine, as well as agricultural waste and industrial byproducts, their utilization in the development of packaging materials can lead to improvements in the oxidative status and antimicrobial properties of food products.
  • 1.9K
  • 18 Nov 2022
Topic Review
The Neuroprotective Potentiality of Flavonoids on Alzheimer’s Disease
Flavonoids are ubiquitous compounds of plants, produced by plants for growth and defense against all kinds of stress, including cold tolerance. More than 6000 different flavonoids have been identified, the primary sources of which are apples, red fruits, onions, citrus fruits, nuts, and beverages such as tea, coffee, beer, and red wine. These compounds, derived from phenol, are particularly interesting for their ability to cross the blood–brain barrier and for their multi-target activity. Several studies have described flavonoids to exhibit relevant biologic activities involving the neuronal antioxidants, as well as anti-amyloidogenic properties, acting as metal chelators, showing anti-inflammatory properties, and ameliorating cognition and neuroprotection.
  • 1.9K
  • 12 Dec 2022
Topic Review Video Peer Reviewed
Flash Radiotherapy: Innovative Cancer Treatment
Flash radiotherapy (Flash-RT) is an innovative technique used in radiotherapy for cancer treatment because it delivers an extremely high dose of radiation (>40 Gy/s) to the tumour in a very short period of time, typically within a fraction of a second. This ultra-fast delivery of radiation distinguishes Flash-RT from conventional radiotherapy, which typically involves the delivery of radiation over a longer time period, often several minutes. Studies conducted in cell and preclinical models suggested that Flash-RT may spare normal tissues from radiation-related side effects, such as skin toxicity, gastrointestinal complications, and damage to organs-at-risk. This is believed to be due to the unique normal tissue response to the ultra-high dose rate. Nevertheless, while Flash-RT shows promising results in preclinical and early clinical studies, one should note that the technique is still in the early stages of development. This entry provides a comprehensive exploration of the immense potentials of Flash-RT, covering its background, mechanisms, radiation sources, recent experimental findings based on cell and preclinical models, and future prospects. It aims to provide valuable insights into this innovative radiotherapy technology for anyone interested in the subject.
  • 1.9K
  • 27 Jun 2023
Topic Review
Spironolactone and XPB
Spironolactone (SP) is commonly used for the treatment of heart failure, hypertension, and complications of cirrhosis by antagonizing the mineralocorticoid receptor. However, SP also antagonizes the androgen receptor, and thus SP has also been shown to be effective in the treatment of acne, hair loss, and hirsutism in women. Interestingly, recent drug repurposing screens have identified new and diverse functions for SP as a simulator of tumor immunosurveillance and as an inhibitor of DNA repair and viral infection. These novel pharmacological effects of SP have all been linked to the ability of SP to induce the rapid proteolytic degradation of the xeroderma pigmentosum group B (XPB) protein. XPB is a critical enzymatic component of the multi-subunit complex known as transcription factor II-H (TFIIH), which plays essential roles in both DNA repair and the initiation of transcription. Given the critical functions for XPB and TFIIH in these processes, the loss of XPB by SP could lead to mutagenesis. However, the ability of SP to promote cancer stem cell death and facilitate immune recognition may counteract the negative consequences of SP to mitigate carcinogenic risk. Thus, SP appears to have new and interesting pharmacological effects that may extend its potential uses.
  • 1.9K
  • 21 Jun 2021
Topic Review
Fluoroquinolones-Associated Disability
Fluoroquinolones (FQs) are one of the most commonly prescribed antibiotics within the United States. FQs are typically included in the treatment protocols of several illnesses such as urinary tract infections, bacterial bronchitis, bacterial gastroenteritis and other infectious diseases. However, it is clear now that FQs lead to severe, long-lasting side effects that require further investigation to ensure better disease management.
  • 1.9K
  • 21 Jul 2021
Topic Review
Malaysian Palm Oil Industry
Oil palm is a highly productive oil crop as it produces up a yield up to ten times higher than other oilseed crops, such as soybean, sunflower and rapeseed, and has a productive life span of over 20 years. As such, oil palm plantations record the highest land productivity. With the growth in population and the surge in renewable energy, palm oil can address those demands by increasing the yield from the existing plantation areas.
  • 1.9K
  • 20 Oct 2021
Topic Review
Carbon Dioxide Fixation by Phytoplankton
Marine phytoplankton account for more than half of the carbon dioxide fixation of Earth. The export of carbon is highest at the photic zone of the ocean, which is dominated by phytoplankton. Plankton can also be zooplanktons that feed on phytoplankton and release fecal pellets that are made of dissolved carbon particles. The growth of the phytoplankton mainly depends upon three factors, i.e., nutrients, sunlight, and carbon dioxide. Phytoplankton-like plants have chlorophyll that fixes carbon dioxide to glucose using the Rubisco enzyme.
  • 1.9K
  • 06 Apr 2022
Topic Review
Role of Marine Drugs in Cardiovascular Diseases Management
Cardiovascular diseases (CVDs) are among the most impactful illnesses globally. The available therapeutic option has several side effects, including hypotension, bradycardia, arrhythmia, and alteration in different ion concentrations. Recently, bioactive compounds from natural sources, including plants, microorganisms, and marine creatures, have gained a lot of interest. Marine sources serve as reservoirs for new bioactive metabolites with various pharmacological activities. The marine-derived compound such as omega-3 acid ethyl esters, xyloketal B, asperlin, and saringosterol showed promising results in several CVDs. 
  • 1.9K
  • 28 Mar 2023
Topic Review
The Role of Magnesium in Muscle Health
Magnesium is an essential mineral that plays a central role in approximately 800 biochemical reactions within the human body. Its distinctive physical and chemical attributes render it an indispensable stabilizing factor in the orchestration of diverse cellular reactions and organelle functions, thereby rendering it irreplaceable in processes directly impacting muscle health.
  • 1.9K
  • 11 Jan 2024
Topic Review
Ionic Liquids in DSSCs
The dye-sensitized solar cells (DSSCs) which are considered as the third-generation solar cells have a huge potential to be commercialized due to their low cost, simplicity in fabrication, and promising photon-to-electrical energy conversion efficiency. Nevertheless, a high cell efficiency can only be achieved when an organic solvent is incorporated into the formulation of the electrolyte, which is prone to evaporation and leakage. As a result, DSSCs become unsuitable for long-run usage due to thermal instability in the electrolyte. The early intention of incorporating ionic liquids (ILs) into the electrolyte was to curb the abovementioned problem and to enable the DSSCs to function as a sustainable energy device. ILs have been incorporated into the electrolyte formulation and the extent of how the ILs can affect the cell efficiency in various electrolyte states is highlighted. This sheds light on the true purpose of introducing ILs into DSSC electrolyte, which is to enhance the ionicity of the electrolyte.
  • 1.9K
  • 26 Sep 2020
Topic Review
Cenozoic Basins-evolution Eastern-External Betic Zone
Four main unconformities (1-4) were recognized in the sedimentary record of the Cenozoic basins of the eastern External Betic Zone. More in detail, they are located at different stratigraphic levels as follows: (1) Cretaceous-Paleogene boundary even if this unconformity was also recorded at the early Paleocene (Murcia sector) and early Eocene (Alicante sector); (2) Eocene-Oligocene boundary and quite synchronous in the whole considered area; (3) early Burdigalian, and quite synchronous (recognized in the Murcia sector); (4) middle Tortonian (recognized in Murcia and Alicante sectors). These unconformities correspond to stratigraphic gaps of different temporal extensions with different meanings, which allowed recognizing minor sedimentary cycles in the Paleocene-Miocene time span. The Cenozoic marine sedimentation started over the oldest unconformity (i.e. the principal one), above the Mesozoic marine deposits. Paleocene-Eocene sedimentation shows numerous tectofacies (such as: turbidites, slumps, olistostromes, mega-olistostromes and pillow-beds) interpreted as related to an early, blind and deep-seated tectonic activity, acting in the more internal subdomains of the External Betic Zone as a result of the geodynamic processes related to the evolution of the westernmost branch of the Tethys. The second unconformity resulted from a Oligocene to Aquitanian sedimentary evolution in the Murcia Sector from marine realms to continental environments. This last time interval is characterized as the previous one by a gentle tectonic activity. On the other hand, the Miocene sedimentation was totally controlled by the development of superficial thrusts and/or bend zones of strike-slip faults both related to the regional geodynamic evolutionary framework linked to the Mediterranean opening. These bends of strike-slip faults created subsidence areas (pull-apart basin-type) and affected the sedimentation lying above the third unconformity. By contrast, the subsidence areas were bounded by structural highs affected by thrusts and folds. After the third unconformity, the Burdigalian-Serravallian sedimentation occurred mainly in shallow- to deep-water marine environments (Tap Fm). During the late Miocene, after the fourth unconformity, the activation of the bend zones of strike-slip faults caused a shallow marine environment sedimentation in the Murcia sector and a continental (lacustrine and fluvial) deposition in the Alicante sector represented, the latter resulting in alluvial fan deposits. Furthermore, the location of these fans changed over time according to the activation of faults responsible for the tectonic rising of Triassic salt deposits, which fed the fan themselves.
  • 1.9K
  • 10 Oct 2020
Topic Review
Bryo-Activities
Usually regarded as less evolved than their more recently diverged vascular sisters, which currently dominate vegetation landscape, bryophytes seem having nothing to envy to the defensive arsenal of other plants, since they had acquired a suite of chemical traits that allowed them to adapt and persist on land.
  • 1.9K
  • 03 Feb 2021
Topic Review
Nitroaromatic Antibiotics
Nitroaromatic antibiotics show activity against anaerobic bacteria and parasites, finding use in the treatment of Heliobacter pylori infections, tuberculosis, trichomoniasis, human African trypanosomiasis, Chagas disease and leishmaniasis.
  • 1.9K
  • 01 Apr 2021
Topic Review
Scanning Electrochemical Microscopy
Scanning electrochemical microscopy (SECM) is a powerful scanning probe technique for measuring the in situ electrochemical reactions occurring at various sample interfaces, such as the liquid-liquid, solid-liquid, and liquid-gas. The tip/probe of SECM is usually an ultramicroelectrode (UME) or a nanoelectrode that can move towards or over the sample of interest controlled by a precise motor positioning system. Remarkably, electrocatalysts play a crucial role in addressing the surge in global energy consumption by providing sustainable alternative energy sources. Therefore, the precise measurement of catalytic reactions offers profound insights for designing novel catalysts as well as for enhancing their performance. SECM proves to be an excellent tool for characterization and screening catalysts as the probe can rapidly scan along one direction over the sample array containing a large number of different compositions. These features make SECM more appealing than other conventional methodologies for assessing bulk solutions. SECM can be employed for investigating numerous catalytic reactions including the oxygen reduction reaction (ORR), oxygen evolution reaction (OER), hydrogen evolution reaction (HER), water oxidation, glucose oxidation reaction (GOR), and CO2 reduction reaction (CO2RR) with high spatial resolution. Moreover, for improving the catalyst design, several SECM modes can be applied based on the catalytic reactions under evaluation.
  • 1.9K
  • 11 May 2021
Biography
Charles Lee Isbell, Jr.
Charles Lee Isbell Jr. is an American computationalist, researcher, and educator. He has been a professor in the Georgia Institute of Technology College of Computing since 2002, and since July 2019 serves as the College's dean. His research interests focus on machine learning and artificial intelligence, particularly interactive and human-centered AI. He has published over 100 scientific papers.
  • 1.9K
  • 16 Nov 2022
Topic Review
Wide Field Infrared Survey Telescope
The Wide Field Infrared Survey Telescope (WFIRST) is a NASA infrared space observatory currently under development. WFIRST was recommended in 2010 by United States National Research Council Decadal Survey committee as the top priority for the next decade of astronomy. On February 17, 2016, WFIRST was approved for development and launch. WFIRST is based on an existing 2.4 m wide field-of-view telescope and will carry two scientific instruments. The Wide-Field Instrument is a 288-megapixel multi-band near-infrared camera, providing a sharpness of images comparable to that achieved by the Hubble Space Telescope (HST) over a 0.28 square degree field of view, 100 times larger than that of the HST. The Coronagraphic Instrument is a high-contrast, small field-of-view camera and spectrometer covering visible and near-infrared wavelengths using novel starlight-suppression technology. The design of WFIRST is based on one of the proposed designs for the Joint Dark Energy Mission between NASA and DOE. WFIRST adds some extra capabilities to the original JDEM proposal, including a search for extra-solar planets using gravitational microlensing. In its present incarnation (2015), a large fraction of its primary mission will be focused on probing the expansion history of the Universe and the growth of cosmic structure with multiple methods in overlapping redshift ranges, with the goal of precisely measuring the effects of dark energy, the consistency of general relativity, and the curvature of spacetime. On February 12, 2018, development on the WFIRST mission was proposed to be terminated in the President's FY19 budget request, due to a reduction in the overall NASA astrophysics budget and higher priorities elsewhere in the agency. However, in March 2018 Congress approved funding to continue making progress on WFIRST until at least September 30, 2018, in a bill stating that Congress "rejects the cancellation of scientific priorities recommended by the National Academy of Sciences decadal survey process".[needs update] In testimony before Congress in July 2018, NASA administrator Jim Bridenstine proposed slowing down the development of WFIRST in order to accommodate a cost increase in the James Webb Space Telescope (JWST), which would result in decreased[clarification needed] funding for WFIRST in 2020/2021. In the President's FY2020 budget request, termination of WFIRST was proposed again, due to cost overruns and higher priority for JWST.. The telescope received $511 million for FY2020.
  • 1.9K
  • 29 Nov 2022
Biography
Charlotte Bühler
Charlotte Bühler (née Malachowski, December 20, 1893 – February 3, 1974) was a German-American developmental psychologist. Bühler was born Charlotte Berta Malachowski in Berlin, the elder of two children of Jewish government architect Hermann Malachowski, and his wife Rose (née Kristeller). After graduating from high school in 1913, Charlotte Malachowski studied natural sciences and hu
  • 1.9K
  • 02 Dec 2022
Topic Review
Main Technological Challenges in Implementing Holographic-Type Communication
Holographic-type communication (HTC) permits new levels of engagement between remote users. It is anticipated that it will give a very immersive experience while enhancing the sense of spatial co-presence. In addition to the newly revealed advantages, however, stringent system requirements are imposed, such as multi-sensory and multi-dimensional data capture and reproduction, ultra-lightweight processing, ultra-low-latency transmission, realistic avatar embodiment conveying gestures and facial expressions, support for an arbitrary number of participants, etc.
  • 1.9K
  • 15 Dec 2022
  • Page
  • of
  • 2799
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback