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Topic Review
Nanomaterial-Based Biosensors for N-Terminal Pro-B-Type Natriuretic Peptide Detection
N-terminal pro-B-type natriuretic peptide (NT-proBNP), a prominent cardiac biomarker, has gained significant recognition for its role in the diagnosis and prognosis of heart failure (HF). This biomarker is synthesized as a response to ventricular volume expansion and pressure overload, conditions often indicative of cardiac stress and dysfunction. The detection of NT-ProBNP, a crucial biomarker for cardiovascular diseases, has been significantly enhanced by the integration of nanomaterials into biosensor designs. These advancements leverage the unique properties of nanomaterials to achieve high sensitivity and specificity in NT-ProBNP detection. 
  • 1.9K
  • 29 Jan 2024
Topic Review
Boötes
Boötes, recognized by the International Astronomical Union (IAU), is a constellation in the northern celestial hemisphere. It is known for its prominent shape resembling a kite or an ice cream cone, with its brightest star, Arcturus, marking one corner.
  • 1.9K
  • 29 Feb 2024
Topic Review
Non-Destructive Insect Infestation Monitoring Systems
In the last two decades, food scientists (engineers) have attempted to develop new technologies that can improve the detection of insect infestation in fruits and vegetables under postharvest conditions using a multitude of non-destructive technologies. While consumers’ expectations for higher nutritive and sensorial value of fresh produce has increased over time, they have also become more critical on using insecticides or synthetic chemicals to preserve food quality from insects’ attacks or enhance the quality attributes of minimally processed fresh produce. In addition, the increasingly stringent quarantine measures by regulatory agencies for commercial import–export of fresh produce needs more reliable technologies for quickly detecting insect infestation in fruits and vegetables before their commercialization. For these reasons, the food industry investigates alternative and non-destructive means to improve food quality. Several studies have been conducted on the development of rapid, accurate, and reliable insect infestation monitoring systems to replace invasive and subjective methods that are often inefficient. There are still major limitations to the effective in-field, as well as postharvest on-line, monitoring applications. The future of non-destructive testing will be enhanced by the current trend in IoT, big data science, and machine learning analysis.
  • 1.9K
  • 18 Feb 2021
Topic Review
Film-Forming Systems
Film-forming formulations represent a novel form of sustained release dermatic products. They are applied to the skin as a liquid or semi-solid preparation.
  • 1.9K
  • 30 Jun 2021
Topic Review
Machine Learning for Temperature Estimation
The modern and very effective methods of estimating the temperature of electric motors include machine learning and deep learning. Their unquestionable advantage is that on the basis of the collected measurement data, a function mapping the relationship between the values of the input features and the output is determined. This means that predictive modeling does not require knowledge of the material properties of a given device or having expertise knowledge about its construction.
  • 1.9K
  • 19 Jul 2021
Topic Review
Nanomaterials for Industrial Wastewater Treatment
Industrial wastewater originating from various industries contributes as a major source of water pollution. This pollutant poses a severe threat to the environment. Recent years saw nanomaterials as a potential candidate for pollutants removal. Nowadays, a range of cost-effective nanomaterials is available with unique properties.
  • 1.9K
  • 22 Jul 2021
Topic Review
B Cell Lymphoma 2 and Cancer Therapy
Bcl-2 is an anti-apoptotic protein that is associated with several cancer progression. Bcl-2 was the first protein to be documented among the Bcl-2 family proteins. It was the first gene exhibited to promote prolonged cell survival and growth rather than enhanced proliferation, which revealed that inhibition of cell death is vital in tumorigenesis.
  • 1.9K
  • 12 Nov 2021
Topic Review
MEMS-Based Tunable Metamaterials
Micro-electro-mechanical systems (MEMS) is a well-known technology that mechanically reconfigures the metamaterial unit cells.
  • 1.9K
  • 18 Jan 2022
Topic Review
Thermal Load and Heat Transfer in Dental Implants
Heat is a kinetic process whereby energy flows from between two systems, hot-to-cold objects. In oro-dental implantology, conductive heat transfer/(or thermal stress) is a complex physical phenomenon to analyze and consider in treatment planning. Hence, ample research has attempted to measure heat-production to avoid over-heating during bone-cutting and drilling for titanium (Ti) implant-site preparation and insertion, thereby preventing/minimizing early (as well as delayed) implant-related complications and failure. The goal is two-fold: (A) the standard heat equation is proposed to be solved, modifying the imposed boundary conditions without any additional source term, and on the other hand, (B) a gap is filled in the literature via obtaining an exact analytical solution of a somewhat simplified problem, which nevertheless, encapsulates the physics and reproduces the results already found in previous works via numerical analyses. In addition, for the first time, the intrinsic time is introduced and involved herein, a “proper” time that characterizes the geometry of the dental implant fixture and overall system, and how the interplay between that time and the exposure time influences temperature changes, and subsequent implant survival, are shown. Thus, this work aims to complement the overall clinical diagnostic and treatment plan for enhanced biological one–implant interface and mechanical implant stability and success rates, whether for immediate or delayed implant loading strategies.
  • 1.9K
  • 11 Mar 2022
Topic Review
Implementing Industry 4.0 Principles and Tools in SME
Small and medium enterprises (SME) face various challenges in order to remain competitive in a global market. Industry 4.0 (I4.0) is increasingly presented as the new paradigm for improving productivity, ensuring economic growth, and guaranteeing the sustainability of manufacturing companies. I4.0 refers to the integration of information technologies (internet of things, cyber–physical systems, cloud computing, AI, etc.) and automation (robots, cobots, automated guided vehicles, etc.) in every sphere of a company, vertically and horizontally, to improve performance. However, SMEs are ill equipped and lack resources to undertake this digital shift. 
  • 1.9K
  • 05 Jul 2022
Topic Review
The Banyan
The Banyan is a non-governmental organization based in Chennai, India was founded in 1993 by Vandana Gopikumar and Vaishnavi Jayakumar to cater to the mentally ill and homeless women in the city. This includes emergency care and critical time interventions offered across 2 hospital based settings, and one shelter for homeless persons with psychosocial disabilities, operated in collaboration with the Corporation of Chennai, reaching out to 162 individuals in distress at any given point of time. Over 3400 individuals have accessed these services since 1993. The Banyan's NALAM programme offers well-being oriented outpatient clinics and community based mental health care in both urban and rural areas. These clinics provide free of charge and mental health and social care services, address distress, common mental disorders and severe mental disorders. They are offered across 15 service access points, reaching out to a population of approximately 7 lakhs. NALAM has reached out to over 10,000 individuals and has a current active registry of 2000 individuals. For those who experience high support needs, The Banyan offers a range of inclusive living options, over 200 individuals with moderate to severe mental health issues, today live in communities & homelike environments with supportive services across 6 districts in 3 States (Tamil Nadu, Kerala, Maharashtra). The Banyan's sister organisation was founded in 2007. BALM uses capacity building, education programmes (diploma, masters’, and PhD programmes) in collaboration with the Tata Institute of Social Sciences (TISS), research, collaborative work (with civil society organisations, local governments, disability movements, mental health user-caregiver groups, and Central and State Government) and construction of think tanks, as strategies to influence progressive policies and plans.
  • 1.9K
  • 18 Oct 2022
Topic Review
Lake Rotoma
Lake Rotoma is the fourth largest lake of the 11 lakes in the Rotorua Lakes district, or the Hot Lakes district as it was known in the early decades of the 20th century. The Rotorua lakes are located in New Zealand's North Island in the Bay of Plenty Region. Lake Rotoma is the easternmost in the chain of three lakes to the northeast of Lake Rotorua The other two are Lake Rotoiti and Lake Rotoehu. Rotoma is located halfway between the city of Rotorua and town of Whakatane. Lake Rotoma has a high water quality with visibility up to around 13 metres deep. The lake has a maximum depth of 83 metres in the northern part and 73.5 metres in the southern part.
  • 1.9K
  • 24 Oct 2022
Topic Review
Common Development and Distribution License
The Common Development and Distribution License (CDDL) is a free and open-source software license, produced by Sun Microsystems, based on the Mozilla Public License (MPL). Files licensed under the CDDL can be combined with files licensed under other licenses, whether open source or proprietary. In 2005 the Open Source Initiative approved the license. The Free Software Foundation (FSF) considers it a free software license, but one which is incompatible with the GNU General Public License (GPL).
  • 1.9K
  • 23 Nov 2022
Topic Review
Data Locality in High Performance Computing
Big data has revolutionized science and technology leading to the transformation of our societies. High-performance computing (HPC) provides the necessary computational power for big data analysis using artificial intelligence and methods. Data locality is a broad term that encapsulates different aspects including bringing computations to data, minimizing data movement by efficient exploitation of cache hierarchies, reducing intra- and inter-node communications, locality-aware process and thread mapping, and in situ and transit data analysis. 
  • 1.9K
  • 17 Jan 2023
Topic Review
Tumor Necrosis Factor-Alpha (TNF-α) in COVID-19
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of 2020 and has affected millions. High levels of proinflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukins are produced readily by innate immune cells to fight Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) infections. The presented work describes the potential of TNF-α in the prognosis, therapeutic and management of COVID-19.
  • 1.9K
  • 06 Apr 2023
Topic Review
Gabor Filters
The use of Gabor filters in image processing has been well-established, and these filters are recognized for their exceptional feature extraction capabilities. These filters are usually applied through convolution.
  • 1.9K
  • 19 Dec 2023
Topic Review
Essential Oils and Terpenes
Essential oils have been used in multiple ways, i.e., inhaling, topically applying on the skin, and drinking. Thus, there are three major routes of intake or application involved: the olfactory system, the skin, and the gastro-intestinal system. Understanding these routes is important for clarifying the mechanisms of action of essential oils. Here we summarize the three systems involved, and the effects of essential oils and their constituents at the cellular and systems level. Many factors affect the rate of uptake of each chemical constituent included in essential oils. It is important to determine how much of each constituent is included in an essential oil and to use single chemical compounds to precisely test their effects. Studies have shown synergistic influences of the constituents, which affect the mechanisms of action of the essential oil constituents. For the skin and digestive system, the chemical components of essential oils can directly activate gamma aminobutyric acid (GABA) receptors and transient receptor potential channels (TRP) channels, whereas in the olfactory system, chemical components activate olfactory receptors. Here, GABA receptors and TRP channels could play a role, mostly when the signals are transferred to the olfactory bulb and the brain.
  • 1.9K
  • 26 Oct 2020
Topic Review
VDAC1
The voltage-dependent anion channel 1 (VDAC1) protein, is an important regulator of mitochondrial function, and serves as a mitochondrial gatekeeper, with responsibility for cellular fate.
  • 1.9K
  • 26 Nov 2020
Topic Review
Hippocampal Malrotation
Hippocampal malrotation (HIMAL) is an increasingly recognized neuroimaging feature but the clinical correlation and significance in epilepsies remain under debate.
  • 1.9K
  • 27 Apr 2021
Topic Review
Genetic Loci Underlying Awn Morphology in Barley
Awns are a transformed leaf blade that extends from the lemmas of the florets, and can contribute significantly to the grain filling via active photosynthesis. Barley awns are highly diverse in morphology, ranging from long to short or awnless types, and from straight to hooded or crooked shapes. The morphological diversity, importance to grain yield and ease of study of barley awns have intrigued plant geneticists for several decades. A large set of genetic loci associated with the development of awns have been identified genetically and mapped to chromosomes.
  • 1.9K
  • 03 Nov 2021
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