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Topic Review
Boyce Thompson Arboretum State Park
Boyce Thompson Arboretum is the largest and oldest botanical garden in the state of Arizona. It is one of the oldest botanical institutions west of the Mississippi. Founded in 1924 as a desert plant research facility and “living museum”, the Arboretum is located in the Sonoran Desert on 392 acres (158.6 ha) along Queen Creek and beneath the towering volcanic remnant, Picketpost Mountain. Boyce Thompson Arboretum is on U.S. Highway 60, an hour's drive east from Phoenix and 3 miles (4.8 km) west of Superior, Arizona. The Arboretum has a visitor center, gift shop, research offices, greenhouses, a demonstration garden, picnic area, and a looping 1.5-mile (2.4 km) primary trail that leads visitors through various exhibits and natural areas. The exhibits include a cactus garden, palm and eucalyptus groves, an Australian exhibit, South American exhibit, aloe garden and an herb garden. There are also side trails such as the Chihuahuan Trail, Curandero Trail, and High Trail. Over 2600 species of arid land plants from around the world grow at the Arboretum. Agaves, aloes, boojum trees, cork oaks, jujube trees, legume trees, and, in the Eucalyptus grove, one of the largest red gum Eucalyptus trees ("Mr. Big") in the United States. Cacti and succulents grow extensively throughout the Arboretum. Because the BTA is a riparian zone, the park attracts Sonoran Desert wildlife and migrating birds. Visitors have seen bobcats, javelinas, coatimundis, rattlesnakes, gila monsters, hawks, hummingbirds, and vultures. 270 bird species have been spotted in the park and the Audubon Society has designated the Arboretum as an Important Bird Area. Currently the Arboretum has 5,000 members and attracts over 75,000 people annually.
  • 826
  • 18 Oct 2022
Topic Review
Calcium-Sensing Receptor in hSMts
Skeletal muscle has an outstanding capacity for regeneration in response to injuries, but there are disorders in which this process is seriously impaired, such as sarcopenia. Pharmacological treatments to restore muscle trophism are not available, therefore, the identification of suitable therapeutic targets that could be useful for the treatment of skeletal reduced myogenesis is highly desirable.
  • 825
  • 12 Jul 2021
Topic Review
Pomegranate Mesocarp against Colitis-Induced Visceral Pain in Rats.
La gestione del dolore viscerale cronico correlato alle malattie infiammatorie intestinali o alla sindrome dell'intestino irritabile è ancora un problema clinico e continuano a essere studiate nuove strategie terapeutiche. Nel presente studio, è stata valutata l'efficacia di un decotto di melograno e dei suoi componenti polisaccaridici ed ellagitanninici nella prevenzione dello sviluppo del dolore addominale indotto da colite nei ratti. Dopo induzione della colite con acido 2,4-dinitrobenzensolfonico (DNBS), decotto di melograno (300 mg kg −1 ), polisaccaridi (300 mg kg −1 ) ed ellagitannini (45 mg kg −1) sono stati somministrati per via orale per 14 giorni. Il trattamento ripetuto con decotto ha ridotto l'ipersensibilità viscerale negli animali colitici sia a 7 che a 14 giorni. Un'efficacia simile è stata dimostrata dai polisaccaridi, ma con minore potenza. Le ellagitannine somministrate a dose equivalente al contenuto di decotto hanno mostrato una maggiore efficacia nel ridurre lo sviluppo del dolore viscerale. Valutazioni macroscopiche e microscopiche eseguite sul colon 14 giorni dopo il danno hanno mostrato che tutte e tre le preparazioni hanno ridotto la quantità complessiva di mastociti, il numero di mastociti degranulati e la densità delle fibre di collagene nello stroma della mucosa. Sebbene gli ellagitannini sembrano essere responsabili della maggior parte degli effetti benefici del melograno sulla colite indotta da DNBS, i polisaccaridi supportano e ne migliorano l'effetto. Perciò,
  • 824
  • 26 Jun 2020
Biography
Robert F. Overmyer
Robert Franklyn "Bob" Overmyer (July 14, 1936 – March 22, 1996), (Col, USMC), was an American test pilot, naval aviator, aeronautical engineer, physicist, United States Marine Corps officer, and United States Air Force /NASA astronaut. He was born in Lorain, Ohio, but considered Westlake, Ohio his hometown. Overmyer was selected by the United States Air Force as an astronaut for its Manned Orb
  • 822
  • 24 Nov 2022
Biography
Michael Dine
Michael Dine (born 12 August 1953, Cincinnati, Ohio) is an American theoretical physicist, specializing in elementary particle physics, supersymmetry, string theory, and physics beyond the Standard Model. Dine received in 1974 a bachelor's degree from Johns Hopkins University and in 1978 a Ph.D. under Thomas Appelquist from Yale University with thesis Interactions of Heavy Quarks in Quantum C
  • 822
  • 13 Dec 2022
Topic Review
Hyperbaric Oxygen Treatment - Cognitive Effects
Hyperbaric oxygen treatment (HBOT)—the medical use of oxygen at environmental pressure greater than one atmosphere absolute—is a very effective therapy for several approved clinical situations, such as carbon monoxide intoxication, incurable diabetes or radiation-injury wounds, and smoke inhalation. In recent years, it has also been used to improve cognition, neuro-wellness, and quality of life following brain trauma and stroke. This opens new avenues for the elderly, including the treatment of neurological and neurodegenerative diseases and improvement of cognition and brain metabolism in cases of mild cognitive impairment.
  • 821
  • 05 Nov 2021
Topic Review
Pittsburgh Refrigerator Cat
The Pittsburgh Refrigerator Cat, Refrigerator Cat, Cold Storage Cat or Eskimo Cat is repeated as fact in many cat books. However, this never existed as a breed. Although Refrigerator Cats are frequently described as a lost longhaired breed, the reports describe them as thick-furred.
  • 821
  • 01 Nov 2022
Biography
James H. Trainor
James H. Trainor (August 22, 1935 – October 4, 2003) was an American physicist. He was born in Lancaster, New Hampshire, the son of Peter D. and Bernice E. Trainor. He graduated in 1953 from Lancaster Academy, where he was the class valedictorian. He attended the University of New Hampshire in Durham, where he received a bachelor of science degree in physics in 1958 and a master's degree i
  • 820
  • 12 Dec 2022
Topic Review
Gel-Based Membranes
Gel-based membranes, a fusion of polymer networks and liquid components, have emerged as versatile tools in a variety of technological domains thanks to their unique structural and functional attributes. Historically rooted in basic filtration tasks, advancements in synthetic strategies have increased the mechanical strength, selectivity, and longevity of these membranes.
  • 819
  • 19 Jan 2024
Topic Review
Photodynamic Therapy in Hepatocellular Carcinoma
Photodynamic Therapy (PDT) relies on local or systemic administration of a light-sensitive dye, called photosensitizer, to accumulate into the target site followed by excitation with light of appropriate wavelength and fluence. This photo-activated molecule reacts with the intracellular oxygen to induce selective cytotoxicity of targeted cells by the generation of reactive oxygen species. 
  • 818
  • 29 Mar 2022
Biography
Cécile DeWitt-Morette
Cécile Andrée Paule DeWitt-Morette (21 December 1922 – 8 May 2017) was a French mathematician and physicist. She founded a summer school at Les Houches in the French Alps. For this and her publications, she was awarded the American Society of the French Legion of Honour 2007 Medal for Distinguished Achievement.[1] Attendees at the summer school included over twenty students who would go on
  • 818
  • 23 Nov 2022
Topic Review
In Re Roslin Institute (Edinburgh)
In re Roslin Institute (Edinburgh), 750 F.3d 1333 (Fed. Cir. 2014), is a 2014 decision of the United States Court of Appeals for the Federal Circuit rejecting a patent for a cloned sheep known as "Dolly the Sheep"— the first mammal ever cloned from an adult somatic cell.
  • 818
  • 01 Dec 2022
Topic Review
Eos (Genus)
Eos is a genus of parrots belonging to the lories and lorikeets tribe of the family Psittaculidae. There are six species which are all endemic to islands of eastern Indonesia, most within very restricted ranges. They have predominantly red plumage with blue, purple or black markings. Males and females are similar in appearance. Their habitats include forest, coconut plantations and mangroves. They gather in flowering trees to feed on nectar and pollen with their brush-tipped tongues. Fruit and insects are also eaten. They make nests in tree hollows generally high in old large trees. Threats to these parrots include habitat loss and trapping for the cagebird trade, and one species, the red-and-blue lory, is classified as endangered.
  • 816
  • 18 Oct 2022
Topic Review
Computational and Statistical Genetics
The interdisciplinary research field of Computational and Statistical Genetics uses the latest approaches in genomics, quantitative genetics, computational sciences, bioinformatics and statistics to develop and apply computationally efficient and statistically robust methods to sort through increasingly rich and massive genome wide data sets to identify complex genetic patterns, gene functionalities and interactions, disease and phenotype associations involving the genomes of various organisms. This field is also often referred to as computational genomics. This is an important discipline within the umbrella field computational biology.
  • 815
  • 07 Nov 2022
Topic Review
Asthma Phenotypes Derived by Data-Driven
Classification of asthma phenotypes has a potentially relevant impact on the clinical management of the disease. Methods for statistical classification without a priori assumptions (data-driven approaches) may contribute to developing a better comprehension of trait heterogeneity in disease phenotyping. 
  • 812
  • 28 Apr 2021
Biography
Juris Upatnieks
Juris Upatnieks (born 7 May 1936 in Riga) is a Latvian-American physicist and inventor, and pioneer in the field of holography. Upatnieks fled the Soviet occupation of Latvia with his parents at the close of World War II, seeking asylum in Germany. In 1951 the family emigrated to the United States. He attended high school in Akron, Ohio, and studied Electrical Engineering at the University of A
  • 812
  • 26 Dec 2022
Topic Review
Ir(III) Complexes with AIE Characteristics for Biological Applications
Both biological process detection and disease diagnosis on the basis of luminescence technology can provide comprehensive insights into the mechanisms of life and disease pathogenesis and also accurately guide therapeutics. As a family of prominent luminescent materials, Ir(III) complexes with aggregation-induced emission (AIE) tendency have been recently explored at a tremendous pace for biological applications, by virtue of their various distinct advantages, such as great stability in biological media, excellent fluorescence properties and distinctive photosensitizing features. Significant breakthroughs of AIE-active Ir(III) complexes have been achieved and great progress has been witnessed in the construction of novel AIE-active Ir(III) complexes and their applications in organelle-specific targeting imaging, multiphoton imaging, biomarker-responsive bioimaging, as well as theranostics.
  • 812
  • 20 Jan 2023
Biography
Aleksei Bach
Alexei Nikolaevich Bach (Russian: Алексей Николаевич Бах; 17 March 1857 Zolotonosha, Poltava Governorate, Russian Empire, now Ukraine - 13 May 1946 Moscow) was a Soviet biochemist and revolutionary.[1] He was a member of the Academy of Sciences of the USSR and senior member of the Supreme Soviet.[2] Bach grew up in Boryspil to a wine distillery technician's family. In 1875
  • 810
  • 07 Dec 2022
Topic Review
Methodologies of Primary HPV Testing
The human papillomavirus is one of the most common sexually transmitted viruses, and an infection from this virus may become persistent, leading to diseases such as cervical cancer. In the past, cytology-based methods such as the Papanicolaou (Pap) test were imperative to identify the disease at a stage where it can be treated. However, since the 1980s where the etiological association of HPV and cervical cancer was identified, new tests began emerging directed towards identifying the virus. Furthermore, as the biology of HPV along with the relationships with its host are elucidated, these tests and treatments further advance. Recently in Europe, there is a movement towards the implementation of HPV testing methodologies in national screening programs to precede cytological testing. These screening strategies are recommended by the European guidelines and the World Health Organization. This review presents the current HPV testing methodologies, their application in organized population-based cervical cancer screening programs based on the most recent European guidelines, and their implementation status in countries in Europe.
  • 807
  • 19 Jul 2021
Topic Review
Microbiota and Pregnancy
Human bacterial colonization starts during fetal life, in opposition to the previous paradigm of the “sterile womb”. Placenta, amniotic fluid, cord blood and fetal tissues each have their own specific microbiota, influenced by maternal health and habits and having a decisive influence on pregnancy outcome and offspring outcome. The maternal microbiota, especially that colonizing the genital system, starts to influence the outcome of pregnancy already before conception, modulating fertility and the success rate of fertilization, even in the case of assisted reproduction techniques. During the perinatal period, neonatal microbiota seems influenced by delivery mode, drug administration and many other conditions. Special attention must be reserved for early neonatal nutrition, because breastfeeding allows the transmission of a specific and unique lactobiome able to modulate and positively affect the neonatal gut microbiota.
  • 806
  • 17 Mar 2021
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