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Topic Review
 m6A RNA Methylation Mechanism
Epitranscriptomic modifications can affect every aspect of RNA biology, including stability, transport, splicing, and translation, participate in global intracellular mRNA metabolism, and regulate gene expression and a variety of biological processes. N6-methyladenosine (m6A) as the most prevalent modification contributes to normal embryonic brain development and memory formation. 
  • 2.1K
  • 08 Jun 2022
Topic Review
Nauka (ISS Module)
Nauka (Russian: Нау́ка; lit. Science), also known as the Multipurpose Laboratory Module (MLM), (Russian: Многофункциональный лабораторный модуль, or МЛМ), is a component of the International Space Station (ISS) which has not yet been launched into space. The MLM is funded by the Roscosmos. In the original ISS plans, Nauka was to use the location of the Docking and Stowage Module. Later, the DSM was replaced by the Rassvet module and it was moved to Zarya's nadir port. Planners anticipate Nauka will dock at Zvezda's nadir port, replacing Pirs. The launch of Nauka, initially planned for 2007, has been repeatedly delayed for various reasons. In May 2020, Nauka was reported to be planned for launch in the second quarter of 2021, after which the warranties of some of Nauka's systems will expire. As of 4 February 2021, Nauka is planned for launch on 15 July 2021.
  • 2.1K
  • 26 Oct 2022
Topic Review
Sloth Bear
The Sloth Bear (Melursus ursinus) is a medium-sized bear species native to the Indian subcontinent. Recognized for its shaggy, coarse fur and distinctively long, curved claws, this primarily insectivorous mammal inhabits a variety of habitats, ranging from dry grasslands to dense forests. The Sloth Bear is characterized by its unique feeding behavior, often observed foraging for termites and ants with its specialized lips and powerful claws, and it plays a crucial role in maintaining ecosystem balance through its impact on insect populations.
  • 2.1K
  • 08 Feb 2024
Topic Review
Preservation (Library and Archival Science)
In library and archival science, preservation is a set of activities aimed at prolonging the life of a record, book, or object while making as few changes as possible. Preservation activities vary widely and may include monitoring the condition of items, maintaining the temperature and humidity in collection storage areas, writing a plan in case of emergencies, digitizing items, writing relevant metadata, and increasing accessibility. Preservation, in this definition, is practiced in a library or an archive by a librarian, archivist, or other professional when they perceive a record is in need of care. Preservation should be distinguished from conservation-restoration of cultural heritage, which refers to the treatment and repair of individual items to slow the process of decay, or restore them to a usable state. Because preservation covers a wide range of efforts aimed at prolonging the life of a record, conservation can be thought of as one of those efforts under the umbrella of preservation. Conservation is occasionally used interchangeably with preservation, particularly outside the professional literature.
  • 2.1K
  • 14 Nov 2022
Topic Review Peer Reviewed
Person-Centered Care: Learning from the Evolution of Mental Health Care
A health care approach that involves service users in decisions concerning their own health. It considers service users’ beliefs, values, support system, and experiences in co-creating an action plan to address their distinct health care goal [this is de novo based on diverse publications about person-centered care].
  • 2.1K
  • 10 Mar 2025
Topic Review
Environmental Impact and Sustainability of Calcium Aluminate Cements
This investigation presents a critical analysis of calcium aluminate cements (CAC), specifically associated with sustainability and environmental impact, and the potential of these cements to help solve certain worldwide problems. Areas of research include cements as recycling holding materials, sustainability, circular economy, production costs, and energy. Here summarizes the current trends, perspectives, and the main concerns regarding CAC. Detailed information about the materials and processes involved in CAC is also presented. First, a general search was made using the Carrot2 Workbench metasearch engine to identify possible thematic groups correlated with CAC, then a more in-depth and specialized search was done using the Scopus database.
  • 2.1K
  • 22 Mar 2022
Topic Review
Optical Coherence Angiography Imaging in Ocular Vascular Diseases
Optical coherence tomography angiography (OCTA) provides us with a non-invasive and efficient means of imaging anterior and posterior segment vasculature in the eye. OCTA has been shown to be effective in imaging diseases such as diabetic retinopathy, retinal vein occlusions, retinal artery occlusions, ocular ischemic syndrome and neovascularization of the iris. It is especially useful with depth-resolved imaging of the superficial, intermediate, and deep capillary plexi in the retina, which enables us to study and closely monitor disease progression and response to treatment. With further advances in technology, OCTA has the potential to become a more widely used tool in the clinical setting and may even supersede ocular angiography in some areas.
  • 2.1K
  • 29 Oct 2020
Topic Review
Liver Fluke, Blood Fluke Vaccines
Liver flukes (Fasciola spp., Opisthorchis spp, Clonorchis sinensis) and blood flukes (Schistosoma spp.) are parasitic helminths causing neglected tropical diseases that result in substantial morbidity afflicting millions globally. Affecting the world’s poorest people, fasciolosis, opisthorchiasis, clonorchiasis and schistosomiasis cause severe disability; hinder growth, productivity and cognitive development; and can end in death. Children are often disproportionately affected. F. hepatica and F. gigantica are also the most important trematode flukes parasitising ruminants and cause substantial economic losses annually. Mass drug administration (MDA) programs for the control of these liver and blood fluke infections are in place in a number of countries but treatment coverage is often low, re-infection rates are high and drug compliance and effectiveness can vary. Furthermore, the spectre of drug resistance is ever-present, so MDA is not effective or sustainable long term. Vaccination would provide an invaluable tool to achieve lasting control leading to elimination.
  • 2.1K
  • 12 Oct 2020
Topic Review
TGF-β Signaling in Tumor Microenvironment
Transforming growth factor-β (TGF-β) signaling triggers diverse biological actions in inflammatory diseases. In tissue fibrosis, it acts as a key pathogenic regulator for promoting immunoregulation via controlling the activation, proliferation, and apoptosis of immunocytes. In cancer, it plays a critical role in tumor microenvironment (TME) for accelerating invasion, metastasis, angiogenesis, and immunosuppression. Increasing evidence suggest a pleiotropic nature of TGF-β signaling as a critical pathway for generating fibrotic TME, which contains numerous cancer-associated fibroblasts, extracellular matrix proteins, and remodeling enzymes. Better understanding the underlying mechanisms may uncover novel therapeutic targets for cancer.
  • 2.1K
  • 28 Jul 2021
Topic Review
New Desalination Plants
This entry analyzes the requirements for the construction of new desalination plants within a framework of sustainability: technology used, energy sources, correction of the environmental impacts generated and appropriate contractual model for their development. These attributes justify that reverse osmosis is the safest and most efficient technology among those available. It is proposed to incorporate renewable energy production sources. The need to adopt corrective measures to mitigate the impact produced on the environment and implement monitoring plans to confirm the validity of these measures will also be demonstrated. Finally, turnkey contracts are proposed because osmosis technology is complex, although the election must be justified by a decision support system.
  • 2.1K
  • 07 Jul 2020
Topic Review
Multi-Microgrid Scheduling
Multi-microgrids address the need for a resilient, sustainable, and cost-effective electricity supply by providing a coordinated operation of individual networks. Due to local generation, dynamic network topologies, and islanding capabilities of hosted microgrids or groups thereof, various new fault mitigation and optimization options emerge. However, with the great flexibility, new challenges such as complex failure modes that need to be considered for a resilient operation, appear. Multi-Microgrid scheduling refers to the procedure of jointly controlling the assets in a multi-microgrid such that the potential of multi-microgrids can be leveraged.
  • 2.1K
  • 26 Oct 2020
Topic Review
MoS2 Energy Applications
MoS2 is one of the transition metal dichalcogenides (TMDs) that has gained a high reputation in recent years due to its distinct chemical, electronic, mechanical, magnetic, and optical properties. Its unique properties enabled its use in different applications such as sensing applications, high-efficiency field effect transistors, and energy and medical (curing) applications. MoS2 exists in different crystalline structures, such as hexagonal (H), tetrahedral (T), or rhombohedral (R). It naturally exists as 2H MoS2, and its most popular structures are the semiconducting 2H and 3R phases and the 1T metallic phase, where 2H is more stable but less conductive than 1T. Metallic MoS2 has a higher conductivity (105 times) than semiconducting 2H MoS2 and high catalytic activity.
  • 2.1K
  • 16 Sep 2021
Topic Review
Fabrication of Metal/Carbon Nanotube Composites by Electrochemical Deposition
Metal/carbon nanotube (CNT) composites are promising functional materials due to the various superior properties of CNTs in addition to the characteristics of metals. Electrochemical deposition can be classified into three types: (1) composite plating by electrodeposition or electroless deposition, (2) metal coating on CNT by electroless deposition, and (3) electrodeposition using CNT templates, such as CNT sheets and CNT yarns. 
  • 2.1K
  • 22 Nov 2021
Topic Review
Croaker Fishery Exploited from the Bay of Bengal
Croakers, locally called Jewfish or Poa mash, are among the largest groups of commercially important fishes exploited from Bangladesh’s Bay of Bengal (BoB) water. Croakers are under the Perciformes order and belong to the family Sciaenidae.
  • 2.1K
  • 10 Jan 2022
Topic Review
Stress in the Aviation Industry
Stress in the aviation industry is a common phenomenon composed of three sources: physiological stressors, psychological stressors, and environmental stressors. Professional pilots can experience stress in flight, on the ground during work-related activities, and during personal time because of the influence of their occupation. An airline pilot can be an extremely stressful job due to the workload, responsibilities and safety of the thousands of passengers they transport around the world. Chronic levels of stress can negatively impact one's health, job performance and cognitive functioning. Being exposed to stress does not always negatively influence humans because it can motivate people to improve and help them adapt to a new environment. Unfortunate accidents start to occur when a pilot is under excessive stress, as it dramatically affects his or her physical, emotional, and mental conditions. Stress "jeopardizes decision-making relevance and cognitive functioning" and it is a prominent cause of pilot error. Being a pilot is considered a unique job that requires managing high workloads and good psychological and physical health. Unlike the other professional jobs, pilots are considered to be highly affected by stress levels. One study states that 70% of surgeons agreed that stress and fatigue don't impact their performance level, while only 26% of pilots denied that stress influences their performance. Pilots themselves realize how powerful stress can be, and yet many accidents and incidents continues to occur and have occurred, such as Asiana Airlines Flight 214, American Airlines Flight 1420, and Polish Air Force Tu-154.
  • 2.1K
  • 28 Sep 2022
Topic Review
Pomphorhynchus Laevis
Pomphorhynchus laevis is an endo-parasitic acanthocephalan worm, with a complex life cycle, that can modify the behaviour of its intermediate host, the freshwater amphipod Gammarus pulex. P. laevis does not contain a digestive tract and relies on the nutrients provided by its host species. In the fish host this can lead to the accumulation of lead in P. laevis by feeding on the bile of the host species.
  • 2.1K
  • 21 Oct 2022
Topic Review
3D Data Acquisition and Object Reconstruction
3D data acquisition and reconstruction is the generation of three-dimensional or spatiotemporal models from sensor data. The techniques and theories, generally speaking, work with most or all sensor types including optical, acoustic, laser scanning, radar, thermal, seismic.
  • 2.1K
  • 10 Nov 2022
Topic Review
Endogenous Enzyme during Meat Processing
Meat aging is a combination of transformations that originate in the animal’s muscle after slaughter, resulting in changes in colour, tenderness and aroma. The biochemical processes that occur during meat aging are mainly caused by endogenous enzymes, leading to glycolysis, proteolysis and lipolysis.
  • 2.1K
  • 12 Jun 2023
Topic Review
Link of Narcissism and Art and Beauty Appreciation
The relationship between narcissistic personality and art and beauty appreciation has become the focus of research investigations. Adaptive narcissists raise their sense of worth in order to shield themselves from harm caused by others. Because they aspire to be more attractive, healthier, and successful versions of themselves, they frequently have greater success in life than the majority of people. Grandiose and overtly narcissistic behavior are the main recognized characteristics of an overt narcissist, which is currently regarded as a personality disorder that puts mental health and wellbeing at peril. 
  • 2.1K
  • 16 Jun 2023
Topic Review
Bacillus amyloliquefaciens
Bacillus amyloliquefaciens, a Gram-positive bacterium, has emerged as a versatile microorganism with significant applications in various fields, including industry, medicine, and agriculture.
  • 2.1K
  • 16 Nov 2023
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