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Topic Review
Gall Formation Induced by Mites and Insects
Publications on gall formation induced on the leaves of dicotyledonous flowering plants by eriophyoid mites (Eriophyoidea) and representatives of four insect orders (Diptera, Hemiptera, Hymenoptera, Lepidoptera) are analyzed. Cellular and molecular level data on the stimuli that induce and sustain the development of both mite and insect galls, the expression of host plant genes during gallogenesis, and the effects of these galling arthropods on photosynthesis are considered. A hypothesis is proposed for the relationship between the size of galls and the volume of secretions injected by a parasite. Multistep, varying patterns of plant gene expression and accompanying histo-morphological changes in the transformed gall tissues are apparent. The main obstacle to better elucidating the nature of the induction of gallogenesis is the impossibility of collecting a sufficient amount of saliva for analysis, which is especially important in the case of microscopic eriophyoids. The use of modern omics technologies at the organismal level has revealed a spectrum of genetic mechanisms of gall formation at the molecular level but has not yet answered the questions regarding the nature of gall-inducing agents and the features of events occurring in plant cells at the very beginning of gall growth.
  • 982
  • 15 Jun 2023
Topic Review
Antimicrobial Activities of Lactoferrins
Lactoferrins are an iron-binding glycoprotein that have important protective roles in the mammalian body through their numerous functions, which include antimicrobial, antitumor, anti-inflammatory, immunomodulatory, and antioxidant activities. Among these, their antimicrobial activity has been the most studied, although the mechanism behind antimicrobial activities remains to be elucidated.
  • 981
  • 28 Oct 2021
Topic Review
Plants Salinity/Water Deficit Responses
Global development has generated a plethora of unfavorable and adverse environmental factors for the living organisms in the ecosystem. Plants are sessile organisms, and they are crucial to sustain life on earth. Since plants are sessile, they face a great number of environmental challenges related to abiotic stresses, such as temperature fluctuation, drought, salinity, flood and metal contamination. Salinity and drought are considered major abiotic stresses that negatively affect the plants’ growth and production of useful content. However, plants have evolved various molecular mechanisms to increase their tolerance to these environmental stresses. There is a whole complex system of communication (cross-talk) through massive signaling cascades that are activated and modulated in response to salinity and drought. Secondary metabolites are believed to play significant roles in the plant’s response and resistance to salinity and drought stress. Until recently, attempts to unravel the biosynthetic pathways were limited mainly due to the inadequate plant genomics resources. However, recent advancements in generating high-throughput “omics” datasets, computational tools and functional genomics approach integration have aided in the elucidation of biosynthetic pathways of many plant bioactive metabolites. 
  • 980
  • 28 Jul 2021
Topic Review
Protective Effects of Thymol on Inflammatory Bowel Disease
Inflammatory bowel disease (IBD) is a gastrointestinal disease that involves chronic mucosal or submucosal lesions that affect tissue integrity. Although IBD is not life-threatening, it sometimes causes severe complications, such as colon cancer. The exact etiology of IBD remains unclear, but several risk factors, such as pathogen infection, stress, diet, age, and genetics, have been involved in the occurrence and aggravation of IBD. Immune system malfunction with the over-production of inflammatory cytokines and associated oxidative stress are the hallmarks of IBD. Dietary intervention and medical treatment suppressing abnormal inflammation and oxidative stress are recommended as potential therapies. Thymol, a natural monoterpene phenol that is mostly found in thyme, exhibits multiple biological functions as a potential adjuvant for IBD.
  • 979
  • 26 Oct 2022
Topic Review
Five Important Seeds in Traditional Medicine
Five important seeds that have tremendous medicinal and pharmacological benefits are anise, basil, borage, cilantro, and chamomile. Anise seed is used as a spice, either whole or ground, and its essential oil and extract are also obtained from the seeds. Basil seeds have a long history of usage in Chinese and Ayurvedic medicine, and they are a good source of minerals, are high in fiber (including pectin), and are rich is flavonoids and other polyphenols. Borage seed oil is used for skin disorders, such as seborrheic dermatitis, atopic dermatitis, and neurodermatitis. Coriander is an annual herb that is part of the Apiaceae family, and the seeds are rich in iron, zinc, copper, and essential minerals, which can decrease bad cholesterol and improve good cholesterol in the body. Chamomile can be considered for the treatment of insomnia, hemorrhoids, anxiety, and diarrhea, and it may help with wound healing and skin irritation. 
  • 979
  • 21 Jul 2023
Topic Review
Effects of Honeybee on Mammals
Honeybee products have positive effects on the reproductive performance of mammals. Many honeybee product constituents are biologically active, with antioxidant, antimicrobial, antiviral, anti-inflammatory, immunomodulatory, antifungal, wound-healing, and cardio-protective properties.
  • 978
  • 13 Jul 2021
Topic Review
Diagnosing Staph Infections with VOC Biomarkers
Staphylococci are broadly adaptable and their ability to grow in unique environments has been widely established, but the most common and clinically relevant staphylococcal niche is the skin and mucous membranes of mammals and birds. S. aureus causes severe infections in mammalian tissues and organs, with high morbidities, mortalities, and treatment costs. S. epidermidis is an important human commensal but is also capable of deadly infections. The development of volatile organic compound (VOC) profiles for the detection and identification of pathogens is an area of intensive research, with significant efforts toward establishing breath tests for infections.
  • 978
  • 13 Mar 2023
Topic Review
Raccoon (Procyon lotor)
The raccoon (Procyon lotor) is a medium-sized, omnivorous mammal native to North America. Recognizable by its characteristic black facial mask and ringed tail, it belongs to the family Procyonidae. Raccoons exhibit notable adaptability and intelligence, allowing them to thrive in a wide range of environments, from forests to urban areas. They are primarily nocturnal and possess dexterous forepaws, which aid in manipulating objects and food.
  • 978
  • 06 Aug 2025
Topic Review
Bearded Seal
The Bearded Seal (Erignathus barbatus) stands as a distinctive and well-adapted marine mammal inhabiting the Arctic and subarctic regions. Recognized for its prominent and lengthy whiskers, or "beards," this species belongs to the family Phocidae and plays a crucial role in Arctic marine ecosystems. With its robust physique and specialized behaviors, the Bearded Seal remains a fascinating subject for researchers studying the unique adaptations of polar marine life.
  • 977
  • 08 Feb 2024
Topic Review
SCF Ligases in Oogenesis and Embryogenesis
SCF (Skp1-Cullin 1-F-box) ligases, which are E3 ubiquitin multi-protein enzymes, catalyse protein ubiquitination and thus allow protein degradation mediated by the 26S proteasome. They play a crucial role in the degradation of cell cycle regulators, regulation of the DNA repair and centrosome cycle and play an important role in several diseases. SCF ligases seem to be needed during all phases of development, from oocyte formation through fertilization, activation of the embryonic genome to embryo implantation.
  • 976
  • 07 Feb 2022
Topic Review
Gastrointestinal Microbiota for Growth and Performance in Chickens
The gut barrier is comprised of intestinal microbiota and their metabolites, mucins secreted by goblet cells, host-derived antimicrobial peptides such as defensins, and cathelicidins, IgA, intestinal epithelium, microfold cells (M cells), Paneth cells, tuft cells and lymphoid tissues in the sub-epithelium and lamina propria. The gut barrier serves to contain the gut microbiota within the lumen while permitting the absorption of nutrients. Intestinal health, tolerance to food and microbial antigens, and homeostasis are achieved through complex interactions between the multiple components in the gut.
  • 976
  • 19 May 2022
Topic Review
Animal Models of Colorectal Cancer
Colorectal cancer is one of the most common gastrointestinal malignancies in humans, affecting approximately 1.8 million people worldwide. This disease has a major social impact and high treatment costs. Animal models allow us to understand and follow the colon cancer progression; thus, in vivo studies are essential to improve and discover new ways of prevention and treatment. Dietary natural products have been under investigation for better and natural prevention, envisioning to show their potential. This manuscript intends to provide the readers a review of rodent colorectal cancer models available in the literature, highlighting their advantages and disadvantages, as well as their potential in the evaluation of several drugs and natural compounds’ effects on colorectal cancer. 
  • 974
  • 09 Jun 2021
Topic Review
Nonsteroidal Anti-Inflammatory Drug (NSAID) Administration
The treatment of dairy cows with nonsteroidal drugs is applied experimentally to investigate the relevance of inflammation during the periparturient period. Despite appearing healthy, dairy cows throughout the transition period and mainly after parturition can develop a pro-inflammatory status that may negatively influence milk production and cows’ health. The administration of nonsteroidal anti-inflammatory drugs (NSAIDs) has been demonstrated to have both positive or negative effects on health and milk production, depending on the type of inhibition mechanism, the dose administered and the cows’ lactation numbers. At present, the safety and efficacy of NSAIDs have not been irrefutably demonstrated; therefore, their use to improve metabolic and inflammatory status, as well as milk production and cow health after parturition, should be carefully evaluated.
  • 974
  • 21 Jul 2021
Topic Review
Development and Growth of Intramuscular Fat in Cattle
Besides protein, beef contains a significant amount of fat. Intramuscular fat (IMF), also referred to as marbling fat, is the white fat deposited within skeletal muscle tissue. The content of intramuscular fat in the skeletal muscle, particularly the longissimus dorsi muscle, of cattle is a critical determinant of beef quality and value. Physiologically, IMF is believed to have similar functions to other fat depots in cattle, serving as an energy reserve and providing fuel during times of increased metabolic demand or inadequate nutrient supply. As food, IMF substantially enhances the texture and flavor of the meat and the overall satisfaction of consumers.
  • 974
  • 27 Feb 2024
Topic Review
Nano-Restoration for Sustaining Soil Fertility
Soil is a real treasure that humans cannot live without. Therefore, it is very important to sustain and conserve soils to guarantee food, fiber, fuel, and other human necessities. Healthy or high-quality soils that include adequate fertility, diverse ecosystems, and good physical properties are important to allow soil to produce healthy food in support of human health. When a soil suffers from degradation, the soil’s productivity decreases. Soil restoration refers to the reversal of degradational processes.
  • 971
  • 27 Sep 2022
Topic Review
COVID-19 in Farm Animals
COVID-19 is caused by the virus SARS-CoV-2 that belongings to the family of Coronaviridae, which has affected multiple species and demonstrated zoonotic potential. The outbreak of COVID-19 has caused pandemic diseases among humans globally so far. The COVID-19 infections were also reported on farm and pet animals, which were discussed and summarized in this study. Although the damage of COVID-19 has not been reported as serious as highly pathogenic avian influenza and African Swine Fever on farm animals so far, the transmission mechanism of COVID-19 among group animals/farms and its long-term impacts are still not clear. Prior to the development of the effective vaccine, the biosecurity measures (e.g., conventional disinfection strategies and innovated technologies) may play roles in preventing potential spread of diseases/viruses.
  • 970
  • 19 Mar 2021
Topic Review
Flavonoid Apigenin and Male Reproductive Health
Apigenin, a common dietary flavonoid abundantly present in a variety of fruits and vegetables, has promising anticancer properties. As an effector of apigenin in myoblasts, protein arginine methyltransferase 7 (Prmt7) is required for male germ cell development. 
  • 969
  • 30 Nov 2021
Topic Review
Coffee Consumption and Insulin Resistance and Sensitivity
Long-term coffee consumption has a nonsignificant effect on insulin resistance and sensitivity. 
  • 969
  • 01 Dec 2021
Topic Review
Chemical Compositions and Biosynthesis of Black Goji Anthocyanins
Lycium ruthenicum is a therapeutic plant and its fruits (black goji) are commonly used as a traditional Chinese medicine. Among the 39 identified black goji anthocyanins (BGAs), most are 3,5-diglycoside derivatives of petunidin (>95%) with an individual anthocyanin [petunidin 3-O-rutinoside (trans-p-coumaroyl)-5-O-glucoside], accounting for 80% of the total BGAs. Due to their unique anthocyanin profile, BGAs possess various health benefits.
  • 969
  • 23 Nov 2022
Topic Review
Agri-Food Contexts in Mediterranean Regions
The agri-food frameworks have specific characteristics (production units with small dimensions and in great number with implications in the respective markets) that call for adjusted approaches, even more so when they are considered in Mediterranean contexts (where global warming will have relevant impacts). In fact, the Mediterranean regions and countries have particular specificities (due to their climate conditions) that distinguish them from their neighbours. This is particularly true in Europe, for example, where the southern countries present socioeconomic dynamics (associated with the respective public debt) that are different from those identified in the northern regions.
  • 968
  • 18 Jun 2021
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