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Topic Review
Application of Cyclodextrins in the Textile Area
Cyclodextrins (CDs) are biocompatible and accepted in biological applications; therefore, there is a growing interest in them both scientifically and industrially. CDs are obtained through the enzymatic degradation of potatoes, corn and rice starch, which gives a mixture of linear, branched, or cyclic dextrins. CDs have a very important role in textile processing and innovation; their use provides immediate opportunities for the development of environmentally friendly products and eco-textiles, in addition to having great potential in various applications. Cyclodextrins can be applied in the areas of spinning, pretreatment, dyeing, finishing, and dye removal, with dyeing, finishing, and water treatment being the most applicable in the textile area registered so far.
  • 2.2K
  • 14 Sep 2022
Topic Review
MultiOTP
multiOTP is an open source PHP class, a command line tool, and a web interface that can be used to provide an operating-system-independent, strong authentication system. multiOTP is OATH-certified since version 4.1.0 and is developed under the LGPL license. Starting with version 4.3.2.5, multiOTP open source is also available as a virtual appliance - as a standard OVA file, a customized OVA file with open-vm-tools, and also as a Hyper-V downloadable file.Template:Jargon-statement A QR code is generated automatically when printing the user-configuration page.
  • 2.2K
  • 21 Nov 2022
Topic Review
Thymoquinone and COVID-19
Thymoquinone (TQ) is the most pharmacologically active ingredient in Nigella sativa seeds (black seeds); it is reported to have anticancer, anti-inflammatory and antioxidant effects in various settings.
  • 2.2K
  • 02 Jun 2021
Topic Review
Conifer Seed Production Enhance
Flowering, the beginning of the reproductive growth, is a significant stage in the growth and development of plants. Conifers are economically and ecologically important, characterized by straight trunks and a good wood quality and, thus, conifer plantations are widely distributed around the world. In addition, conifer species have a good tolerance to biotic and abiotic stress, and a stronger survival ability. Seeds of some conifer species, such as Pinus koraiensis, are rich in vitamins, amino acids, mineral elements and other nutrients, which are used for food and medicine. Although conifers are the largest (giant sequoia) and oldest living plants (bristlecone pine), their growth cycle is relatively long, and the seed yield is unstable. Flowering and seed yields in conifers are affected by a variety of factors, such as pollen, temperature, light, water availability, nutrients, etc., and a number of management techniques, including topping off, pruning, fertilization, hormone treatment, supplementary pollination, etc. has been developed for improving cone yields.
  • 2.2K
  • 13 Sep 2021
Topic Review
Comparison Between Esperanto and Ido
Ido, like Esperanto, is a constructed international auxiliary language. L. L. Zamenhof published his constructed language under the pseudonym Dr Esperanto in 1887. It immediately became popular, but soon people were making suggestions as to how they thought it might be improved. Zamenhof responded by making a list of possible changes to Esperanto and in 1894 put them before the Esperanto community. If accepted they would create what Dr Zamenhof called "a Reformed Esperanto". This proposed reformed Esperanto is sometimes referred to as Esperanto 1894. However, when the Esperanto community was invited to vote on whether to adopt the proposals, they rejected the proposals by a large majority. Ido was created around a quarter of a century after Esperanto. The name Ido means "offspring" in Esperanto and was so named by its creators because it was a development of Esperanto. The creation of Ido led to a schism between those who believed that Esperanto should be left as it was and those who believed that it had what they perceived as inherent flaws which made it not quite good enough to be the world's international auxiliary language. Those who opposed change maintained that it was endless tinkering that had led, in their opinion, to the decline of Volapük a once popular constructed language that had predated Esperanto's publication by a few years. They would also surely have pointed out that Dr Zamenhof's reform proposals of 1894 had been rejected by popular vote. The languages of Esperanto and Ido remain close, and largely mutually intelligible, like two dialects of the same language. Just as dialects of a language are quite often sources of new words for that language through literature, so Ido has contributed many neologisms to Esperanto (especially in poetic substitutes for long words using the mal- prefix). One study conducted with 20 college students at Columbia University circa 1933 suggests that Esperanto's system of correlative words is easier to learn than Ido's. Two other studies by the same researchers suggest no significant overall difference in difficulty of learning between Esperanto and Ido for educated American adults, but the sample sizes were again small: in the two tests combined, only 32 test subjects studied Ido. The researchers concluded that additional comparative studies of Esperanto and Ido are needed.
  • 2.2K
  • 09 Oct 2022
Topic Review
Flux Classification
Flux is a granular material that primarily consists of oxides and CaF2. The manufacturing method plays an important role in shaping the flux features.
  • 2.2K
  • 09 Dec 2022
Topic Review
Dual-Layer Spectral Computed Tomography
The advance in technology allows for the development of different CT scanners in the field of dual-energy computed tomography (DECT). In particular, a recently developed detector-based technology can collect data from different energy levels, thanks to its layers. The use of this system is suited for material decomposition with perfect spatial and temporal registration. Thanks to post-processing techniques, these scanners can generate conventional, material decomposition (including virtual non-contrast (VNC), iodine maps, Z-effective imaging, and uric acid pair images) and virtual monoenergetic images (VMIs). 
  • 2.2K
  • 06 Jun 2023
Topic Review
Polyamines
Polyamines (PAs), such as putrescine (PUT), spermine (SPE), and spermidine (SPD), are organic polycationic alkylamines, which are synthesized from L-ornithine or by the decarboxylation of amino acids. They are found in all living cells and mammalian cells contain a millimolar concentration of PAs. In 1678, the SPE was first identified by Van Leeuwenhoek as crystals in dried semen but not in fresh ones.
  • 2.2K
  • 28 Jun 2021
Topic Review
Organic Germanium Compounds
Germanium is an essential microelement, and its deficiency can result in numerous diseases, particularly oncogenic conditions. Consequently, water-soluble germanium compounds, including inorganic and coordination compounds, have attracted significant attention due to their biological activity. 
  • 2.2K
  • 01 Jun 2023
Topic Review
Nanoporous Anodic Alumina
Nanoporous Anodic Alumina (NAA) is formed by the electrochemical anodization of pure aluminum wafers and consists of a parallel array of pores surrounded by hexagonal cells of aluminum oxide (alumina).
  • 2.2K
  • 25 Mar 2021
Topic Review
Drug Resistance Mechanisms in Tuberculosis
The increased incidence of multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) strains, defined as resistant to at least isoniazid and rifampin, the two highly bactericidal first-line drugs, is a major concern for tuberculosis (TB) control. The worldwide estimate of almost half a million incident cases of MDR/rifampin-resistant TB, is causing increasing concern. In this view, it is important to continuously update the knowledge on the mechanisms involved in the development of drug-resistant TB. Clinical, biological and microbiological reasons account for the generation of resistance, including: (i) nonadherence of patients to their therapy, and/or errors of physicians in therapy management, (ii) complexity and poor vascularization of granulomatous lesions, which obstruct drug distribution to some sites, resulting in resistance development, (iii) intrinsic drug resistance of tubercle bacilli, (iv) formation of non-replicating, drug-tolerant bacilli inside the granulomas, (v) development of mutations in Mtb genes, which are the most important molecular mechanisms of resistance. Here, a piece of information on the interplay of these factors is provided, to facilitate the clinical and microbiological management of drug-resistant TB at the global level, with attention also to the most recent diagnostic methods.
  • 2.2K
  • 21 Apr 2020
Topic Review
Milk Proteins
Milk and colostrum have high biological potential, and due to their natural origin and non-toxicity, they have many uses in cosmetics and dermatology. Research is ongoing on their potential application in other fields of medicine, but there are still few results; most of the published ones are included in this entry. These natural products are especially rich in proteins, such as casein, β-lactoglobulin, α-lactalbumin, lactoferrin, immunoglobulins, lactoperoxidase, lysozyme, and growth factors, and possess various antibacterial, antifungal, antiviral, anticancer, antioxidant, immunomodulatory properties, etc. 
  • 2.2K
  • 22 Jun 2021
Topic Review
Bacterial Flagellar Filament
The bacterial flagellum is a complex and dynamic nanomachine that propels bacteria through liquids. It consists of a basal body, a hook, and a long filament. The flagellar filament is composed of thousands of copies of the protein flagellin (FliC) arranged helically and ending with a filament cap composed of an oligomer of the protein FliD. The overall structure of the filament core is preserved across bacterial species, while the outer domains exhibit high variability, and in some cases are even completely absent. Flagellar assembly is a complex and energetically costly process triggered by environmental stimuli and, accordingly, highly regulated on transcriptional, translational and post-translational levels. Apart from its role in locomotion, the filament is critically important in several other aspects of bacterial survival, reproduction and pathogenicity, such as adhesion to surfaces, secretion of virulence factors and formation of biofilms. Additionally, due to its ability to provoke potent immune responses, flagellins have a role as adjuvants in vaccine development.
  • 2.2K
  • 02 Aug 2021
Topic Review
Haptic Assistive Driving Systems with Human Operators
With the availability of modern assistive techniques, ambient intelligence, and the Internet of Things (IoT), various innovative assistive environments have been developed, such as driving assistance systems (DAS), where the human driver can be provided with physical and emotional assistance. In this human–machine collaboration system, haptic interaction interfaces are commonly employed because they provide drivers with a more manageable way to interact with other components. From the view of control system theory, this is a typical closed-loop feedback control system with a human in the loop. To make such a system work effectively, both the driving behaviour factors, and the electrical–mechanical components should be considered. However, the main challenge is how to deal with the high degree of uncertainties in human behaviour. 
  • 2.2K
  • 19 Jul 2022
Topic Review
XC (Programming Language)
In computers, XC is a programming language for real-time embedded parallel processors, targeted at the XMOS XCore processor architecture. XC is an imperative language, based on the features for parallelism and communication in occam, and the syntax and sequential features of C. It provides primitive features that correspond to the various architectural resources provided, namely: channel ends, locks, ports and timers. In combination with XCore processors, XC is used to build embedded systems with levels of I/O, real-time performance and computational ability usually attributed to field-programmable gate arrays (FPGAs) or application-specific integrated circuit (ASIC) devices.
  • 2.2K
  • 28 Oct 2022
Topic Review
Research Trends of Protected Areas and Nature-Based Tourism
Nature-based tourism (NBT) represents a significant sector within global tourism, which may represent approximately 20% of the global tourism market. In parallel, many natural areas and ecosystems are threatened by challenges related to climate change, biodiversity loss, and anthropogenic activities, calling into question their sustainability.
  • 2.2K
  • 13 Nov 2023
Topic Review
Ubiquitin-Specific Peptidase (USP) Inhibitors
Ubiquitylation and deubiquitylation are reversible protein post-translational modification (PTM) processes involving the regulation of protein degradation under physiological conditions. Loss of balance in this regulatory system can lead to a wide range of diseases, such as cancer and inflammation. As the main members of the deubiquitinases (DUBs) family, ubiquitin-specific peptidases (USPs) are closely related to biological processes through a variety of molecular signaling pathways, including DNA damage repair, p53 and transforming growth factor-β (TGF-β) pathways.
  • 2.2K
  • 11 Jun 2021
Topic Review
FDA-Approved Multiple Sclerosis Drugs
The molecular effects of traditional and more recently FDA-approved Multiple Sclerosis (MS) drugs on four CNS cell types.
  • 2.2K
  • 26 Oct 2020
Topic Review
Syndrome of Undifferentiated Recurrent Fever
Syndrome of undifferentiated recurrent fever (SURF) is a heterogeneous group of autoinflammatory diseases (AID) characterized by self-limiting episodes of systemic inflammation without a confirmed molecular diagnosis, not fulfilling the criteria for periodic fever, aphthous stomatitis, pharyngitis and adenopathy (PFAPA) syndrome.
  • 2.2K
  • 13 May 2021
Topic Review
Reverse Osmosis
Reverse osmosis is the leading technology for desalination of brackish water and seawater, important for solving the growing problems of fresh water supply.
  • 2.2K
  • 23 Jul 2021
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