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Topic Review
Clostridium Difficile Infection
Clostridium difficile infection (CDI or C-dif) is a symptomatic infection due to the spore-forming bacterium, Clostridium difficile. Symptoms include watery diarrhea, fever, nausea, and abdominal pain. It makes up about 20% of cases of antibiotic-associated diarrhea. Complications may include pseudomembranous colitis, toxic megacolon, perforation of the colon, and sepsis. Clostridium difficile infection is spread by bacterial spores found within feces. Surfaces may become contaminated with the spores with further spread occurring via the hands of healthcare workers. Risk factors for infection include antibiotic or proton pump inhibitors use, hospitalization, other health problems, and older age. Diagnosis is by stool culture or testing for the bacteria's DNA or toxins. If a person tests positive but has no symptoms, the condition is known as C. difficile colonization rather than an infection. Prevention is by hand washing, terminal room cleaning in hospital, and limiting antibiotic use. Discontinuation of antibiotics may result in resolution of symptoms within three days in about 20% of those infected. Often the antibiotics metronidazole, vancomycin or fidaxomicin will cure the infection. Retesting after treatment, as long as the symptoms have resolved, is not recommended, as the person may remain colonized. Recurrences have been reported in up to 25% of people. Some tentative evidence indicates fecal microbiota transplantation and probiotics may decrease the risk of recurrence. C. difficile infections occur in all areas of the world. About 453,000 cases occurred in the United States in 2011, resulting in 29,000 deaths. Rates of disease globally have increased between 2001 and 2016. Women are more often affected than men. The bacterium was discovered in 1935 and found to be disease-causing in 1978. In the United States, health–care associated infections increase the cost of care by US$1.5 billion each year.
  • 2.3K
  • 07 Nov 2022
Topic Review
Bottle Conditioning
Bottle conditioning refers to a method of adding fermenting wort or yeast suspension in sugar solution into beer in its final package. Additionally denoted as bottle refermentation, this technique has been originally developed to assure beer carbonation, and has further significance related to formation of distinctive sensory attributes and enhancement of sensory stability, which are the phenomena associated with ongoing yeast metabolic activities in the final package.
  • 2.3K
  • 23 Sep 2020
Topic Review
Biological Nitrogen Fixation
In agroecosystems, nitrogen is one of the major nutrients limiting plant growth. To meet the increased nitrogen demand in agriculture, synthetic fertilizers have been used extensively in the latter part of the twentieth century, which have led to environmental challenges such as nitrate pollution. Biological nitrogen fixation (BNF) in plants is an essential mechanism for sustainable agricultural production and healthy ecosystem functioning. BNF by legumes and associative, endosymbiotic, and endophytic nitrogen fixation in non-legumes play major roles in reducing the use of synthetic nitrogen fertilizer in agriculture, increased plant nutrient content, and soil health reclamation. 
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  • 24 Nov 2021
Topic Review
Sprouts and Microgreens for Healthy Diets
Healthy diets prevent diet-related non-communicable diseases; they provide nutrients and health-promoting substances from nutritious foods in adequate amounts. With society's growing interest in healthy eating, the interest in fresh, ready-to-eat, functional food, such as microscale vegetables (sprouted seeds and microgreens), has been on the rise in recent years globally. This entry briefly describes the crops commonly used for microscale vegetable production, highlights Brassica vegetables because of their health-promoting secondary metabolites and looks at consumer acceptance of sprouts and microgreens. Landraces, wild food plants, and crops' wild relatives often have high phytonutrient density and exciting flavours and tastes, thus providing scope to widen the range of crops and species used for this purpose. Moreover, the nutritional value and content of phytochemicals often vary with plant growth and development stages of the same crop. Sprouted seeds and microgreens are often more nutrient-dense than ungerminated seeds or mature vegetables. This entry also describes the environmental and priming factors that may impact the nutritional value and content of phytochemicals of microscale vegetables. Due to their short growth cycle, nutrient-dense sprouts and microgreens can be produced with minimal input and without pesticides. They can even be home-grown and harvested as needed, hence having low environmental impacts and a broad acceptance among health-conscious consumers.
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  • 21 Mar 2022
Topic Review
Information Technology Rules, 2021
The Information Technology (Intermediary Guidelines and Digital Media Ethics Code) Rules, 2021 is secondary or subordinate legislation that suppresses India 's Intermediary Guidelines Rules 2011. The 2021 rules have stemmed from section 87 of the Information Technology Act, 2000 and are a combination of the draft Intermediaries Rules, 2018 and the OTT Regulation and Code of Ethics for Digital Media. The Central Government of India along with the Ministry of Electronics and Information Technology (MeitY) and the Ministry of Information and Broadcasting (MIB) have coordinated in the development of the rules. Intermediaries had until 25 May 2021 to comply with the rules.
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  • 10 Oct 2022
Topic Review
Nordic Folkboat
The Nordic Folkboat (Swedish: Nordisk Folkbåt) is a Swedish sailboat that was designed by Jac Iversen (sv) and Tord Sundén as a racer-cruiser and first built in 1942. Even though Sundén drafted the plans with design ideas provided by Iversen, Sundén was never credited as the actual designer of the boat. The Nordic Folkboat was developed into the Sundén-designed International Folkboat in 1967. The International Folkboat was expressly designed for fibreglass construction. The International 25 and the Olsen 26 are also based upon this design. The Junior Folkboat designed by Erik Salander (båtkonstruktör) (sv) actually dates from 1929. It was originally called the "Juniors Bad" (Junior boat), but was latter renamed because of its strong resemblance to the later and larger Nordic Folkboat.
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  • 04 Nov 2022
Topic Review
Anisakidae Family
Nematodes of the Anisakidae family have a cosmopolitan distribution, due to their ability to infest a wide variety of aquatic hosts during the development of their larval stages, mainly marine mammals and aquatic birds, such as pelicans; being the hosts where the life cycle is completed. The participation of intermediate hosts such as cephalopods, shrimp, crustaceans and marine fish, are an important part to complete this cycle. However, its importance in human health is due to its zoonotic capacity, which causes the clinical presentation in humans, known as Anisakiasis or Anisakidosis, depending on the species of the infecting parasite.
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  • 16 Dec 2020
Topic Review
List of Numerical Analysis Software
Listed here are end-user computer applications intended for use with numerical or data analysis:
  • 2.3K
  • 17 Oct 2022
Topic Review
Prenuptial Agreement
A prenuptial agreement, antenuptial agreement, or premarital agreement (commonly referred to as a prenup), is a written contract entered into by a couple prior to marriage or a civil union that enables them to select and control many of the legal rights they acquire upon marrying, and what happens when their marriage eventually ends by death or divorce. Couples enter into a written prenuptial agreement to supersede many of the default marital laws that would otherwise apply in the event of divorce, such as the laws that govern the division of property and retirement benefits and savings, and the right to seek alimony (spousal support) with agreed-upon terms that provide certainty and clarify their marital rights. A premarital agreement may also contain waivers of a surviving spouse’s right to claim an elective share of the estate of the deceased spouse. In some countries, including the United States , Belgium and the Netherlands, the prenuptial agreement not only provides for what happens in the event of a divorce, but also to protect some property during the marriage, for instance in case of a bankruptcy. Many countries, including Canada , France , Italy, and Germany , have matrimonial regimes, in addition to, or some cases, in lieu of prenuptial agreements. Postnuptial agreements are similar to prenuptial agreements, except that they are entered into after a couple is married. When divorce is imminent, postnuptial agreements are referred to as separation agreements.
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  • 25 Oct 2022
Topic Review
Server Immersion Cooling
Immersion cooling is an IT cooling practice by which IT components and other electronics, including complete servers, are submerged in a thermally conductive dielectric liquid or coolant. Heat is removed from the system by circulating liquid into direct contact with hot components, then through cool heat exchangers. Fluids suitable for immersion cooling have very good insulating properties to ensure that they can safely come into contact with energized electronic components.
  • 2.3K
  • 08 Nov 2022
Topic Review
DAISY Digital Talking Book
DAISY (Digital Accessible Information SYstem) is a technical standard for digital audiobooks, periodicals and computerized text. DAISY is designed to be a complete audio substitute for print material and is specifically designed for use by people with "print disabilities", including blindness, impaired vision, and dyslexia. Based on the MP3 and XML formats, the DAISY format has advanced features in addition to those of a traditional audio book. Users can search, place bookmarks, precisely navigate line by line, and regulate the speaking speed without distortion. DAISY also provides aurally accessible tables, references and additional information. As a result, DAISY allows visually impaired listeners to navigate something as complex as an encyclopedia or textbook, otherwise impossible using conventional audio recordings. DAISY multimedia can be a book, magazine, newspaper, journal, computerized text or a synchronized presentation of text and audio. It provides up to six embedded "navigation levels" for content, including embedded objects such as images, graphics, and MathML. In the DAISY standard, navigation is enabled within a sequential and hierarchical structure consisting of (marked-up) text synchronized with audio. DAISY 2 was based on XHTML and SMIL. DAISY 3 is a newer technology, also based on XML, and is standardized as ANSI/NISO Z39.86-2005. The DAISY Consortium was founded in 1996 and consists of international organizations committed to developing equitable access to information for people who have a print disability. The consortium was selected by the National Information Standards Organization (NISO) as the official maintenance agency for the DAISY/NISO Standard.
  • 2.3K
  • 09 Nov 2022
Topic Review
Flavonoid Production in Plant Metabolic Engineering
Flavonoids are secondary metabolites that represent a heterogeneous family of plant polyphenolic compounds. The research has determined that the health benefits of fruits and vegetables, as well as the therapeutic potential of medicinal plants, are based on the presence of various bioactive natural products, including a high proportion of flavonoids. In plant metabolite research, flavonoids have become the center of attention due to their significant bioactivity associated with anti-cancer, antioxidant, anti-inflammatory, and anti-microbial activities.
  • 2.3K
  • 31 Jan 2023
Topic Review
Bush Dog
The Bush Dog (Speothos venaticus) emerges as a captivating and elusive canid species, residing in the dense and remote habitats of Central and South America. Recognized for its unique appearance and social behaviors, the Bush Dog stands out as a small yet highly specialized predator within the intricate tapestry of neotropical ecosystems. This elusive canid's cryptic lifestyle and distinctive pack dynamics make it a subject of intrigue for wildlife enthusiasts and researchers alike.
  • 2.3K
  • 04 Feb 2024
Topic Review
Survivor Guilt
Survivor guilt (or survivor's guilt; also called survivor syndrome or survivor's syndrome and survivor disorder or survivor's disorder) is a mental condition that occurs when a person believes they have done something wrong by surviving a traumatic or tragic event when others did not, often feeling self-guilt. The experience and manifestation of survivor's guilt will depend on an individual's psychological profile. When the Diagnostic and Statistical Manual of Mental Disorders IV (DSM-IV) was published, survivor guilt was removed as a recognized specific diagnosis, and redefined as a significant symptom of post-traumatic stress disorder (PTSD). It may be found among survivors of combat, epidemics, murder, natural disasters, rape, terrorism, accidents, among the friends and family of those who have died by suicide, and in non-mortal situations.
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  • 22 Nov 2022
Topic Review
CPC with a Tubular Absorber
The compound parabolic concentrator (CPC) is a highly interesting solar collector technology for different low-concentration applications due to no tracking requirement. The CPC with a tubular absorber is the most common type of CPC. 
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  • 27 Sep 2021
Topic Review
LINE1 Retrotransposons
LINE-1 (L1) is a class of autonomous mobile genetic elements that form somatic mosaicisms in various tissues of the organism. The activity of L1 retrotransposons is strictly controlled by many factors in somatic and germ cells at all stages of ontogenesis. Alteration of L1 activity was noted in a number of diseases: in neuropsychiatric and autoimmune diseases, as well as in various forms of cancer.
  • 2.3K
  • 20 Oct 2021
Topic Review
Family Influence Adolescent Eating Habits
Promoting healthy eating habits can prevent adolescent obesity in which family may play a significant role. Ten themes on how family influences adolescent dietary KAP were found: Knowledge—(1) parental education, (2) parenting style, and (3) family illness experience; Attitudes—(4) family health, (5) cultivation of preference, and (6) family motivation; Practices—(7) home meals and food availability, (8) time and cost, (9) parenting style, and (10) parental practical knowledge and attitudes. 
  • 2.3K
  • 22 Nov 2021
Topic Review
Zero Liquid Discharge System for the Tannery Industry
The tannery industry is characterized by the consumption of a large quantity of water, around 30–40 m3 for processing 1000 kg of hide or skin. This amount becomes wastewater, containing about 300 kg of different chemicals, mainly refractory organic compounds, with high chemical oxygen demand (COD), total dissolved salts (TDS), chromium, and evolution of toxic gases, such as ammonia and sulfides, etc. The remaining tanning chemicals are released as effluent having high resistance against biological degradation, becoming a serious environmental issue. The Zero Liquid Discharge (ZLD) system serves to ensure zero water emission, as well as treatment facilities by recycling, recovery, and reuse of the treated wastewater using advanced cleanup technology. The international scenario shows the implementation of ZLD thanks to pressure from regulatory agencies. The ZLD system consists of a pre-treatment system with conventional physicochemical treatment, tertiary treatment, softening of the treated effluent, reverse osmosis (RO) treatment for desalination, and thermal evaporation of the saline reject from RO to separate the salts. By adopting this system, water consumption is reduced. Moreover, ZLD also becomes effective in disaster mitigation in areas where the tannery industry is a strong economic actor. 
  • 2.3K
  • 27 Jun 2022
Topic Review
Antimicrobial Effects of Antimicrobial Peptides
The growing emergence of antimicrobial resistance represents a global problem that not only influences healthcare systems but also has grave implications for political and economic processes. As the discovery of novel antimicrobial agents is lagging, one of the solutions is innovative therapeutic options that would expand our armamentarium against this hazard. Compounds of interest in many such studies are antimicrobial peptides (AMPs), which actually represent the host’s first line of defense against pathogens and are involved in innate immunity. They have a broad range of antimicrobial activity against Gram-negative and Gram-positive bacteria, fungi, and viruses, with specific mechanisms of action utilized by different AMPs.
  • 2.3K
  • 18 Oct 2022
Topic Review
Comparison of Remote Sensing Satellites
A variety of remote sensing systems exist, for which the specification is distributed among a variety of websites from data providers, satellite operators and manufacturers. In order to choose a data product for a given project, a remote sensing data user must be aware of the different products and their applications. The table below gives users an overview of major remote sensing systems and datasets and summarizes their applications and systems.
  • 2.3K
  • 20 Oct 2022
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