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Topic Review
Olive Tree and Derivatives
Olive (Olea europaea) is one of the most extensive crops in the Mediterranean countries, and an important source of extra distinctive compounds that has been widely tested due to its known health benefits. Olive derivatives, such as extra virgin olive oil (EVOO) and olive leaves are rich in antioxidant compounds such as hydroxytyrosol (HXT) and oleuropein and oleic acid, as main monounsaturated fatty acid. Because of HXT molecular structure, its regular consumption reports important beneficial properties such as anti-inflammatory, antimicrobial, antioxidant, and anticancer, which also make this compound a good preservative agent against meat deterioration and spoilage.
  • 2.4K
  • 30 Nov 2021
Topic Review
Diabetic Retinopathy
Diabetic retinopathy (DR) is the most frequent microvascular complication of long-term diabetes and the most common cause of blindness, increasing morbidity in the working-age population. The most effective therapies for these complications include laser photocoagulation and anti-vascular endothelial growth factor (VEGF) intravitreal injections. However, laser and anti-VEGF drugs are untenable as a final solution as they fail to address the underlying neurovascular degeneration and ischemia. Regenerative medicine may be a more promising approach, aimed at the repair of blood vessels and reversal of retinal ischemia. Stem cell and tissue engineering therapy have introduced a novel way to reverse the underlying ischemia present in microvascular complications in diseases such as diabetes. 
  • 2.4K
  • 30 Oct 2020
Topic Review
HiPSC-Derived Cardiac Tissue
Relevant, predictive normal, or disease model systems are of vital importance for drug development. The difference between nonhuman models and humans could contribute to clinical trial failures despite ideal nonhuman results. As a potential substitute for animal models, human induced pluripotent stem cell (hiPSC)-derived cardiomyocytes (CMs) provide a powerful tool for drug toxicity screening, modeling cardiovascular diseases, and drug discovery.
  • 2.4K
  • 14 Dec 2020
Topic Review
Coordinative Carbon and Nitrogen Metabolism
C and N are the most important essential elements constituting organic compounds in plants. The shoots and roots depend on each other by exchanging C and N through the xylem and phloem transport systems. Complex mechanisms regulate C and N metabolism to optimize plant growth, agricultural crop production, and maintenance of the agroecosystem. 
  • 2.4K
  • 22 Jan 2021
Topic Review
Network Function Virtualization and Service Function Chaining Frameworks
Network slicing has become a fundamental property for next-generation networks, especially because an inherent part of 5G standardisation is the ability for service providers to migrate some or all of their network services to a virtual network infrastructure, thereby reducing both capital and operational costs. With network function virtualisation (NFV), network functions (NFs) such as firewalls, traffic load balancers, content filters, and intrusion detection systems (IDS) are either instantiated on virtual machines (VMs) or lightweight containers, often chained together to create a service function chain (SFC). 
  • 2.4K
  • 01 Mar 2022
Topic Review
Liquid Hydrogen in the Transportation Sector
The European Green Deal aims to transform the EU into a modern, resource-efficient, and competitive economy. The REPowerEU plan launched in May 2022 as part of the Green Deal reveals the willingness of several countries to become energy independent and tackle the climate crisis. Therefore, the decarbonization of different sectors such as maritime shipping is crucial and may be achieved through sustainable energy. Hydrogen is potentially clean and renewable and might be chosen as fuel to power ships and boats. Hydrogen technologies (e.g., fuel cells for propulsion) have already been implemented on board different types of vehicles mainly during demonstration projects.
  • 2.4K
  • 08 Oct 2022
Topic Review
Karst Plateau (Italy-Slovenia)
The Karst Plateau or the Karst region (Slovene: Kras, Italian: Carso), also locally called Karst, is a karst plateau region extending across the border of southwestern Slovenia and northeastern Italy. It lies between the Vipava Valley, the low hills surrounding the valley, the westernmost part of the Brkini Hills, northern Istria, and the Gulf of Trieste. The western edge of the plateau also marks the traditional ethnic border between Italians and Slovenes. The region gave its name to karst topography. For this reason, it is also referred to as the Classical Karst.
  • 2.4K
  • 04 Nov 2022
Topic Review
Role of Lactobacillus in the Female Reproductive Tract
The eubiotic vaginal microbiota of reproductive-aged women is composed mostly of various Lactobacillus species (spp.), which exert protective effects via the production of lactic acid, bacteriocins, polysaccharides, peptidoglycans, and hydrogen peroxide (H2O2), lowering pH, raising the viscosity of cervicovaginal mucus, and hampering both the adhesion of cells to epithelial tissue and the entry of HPV. The depletion of beneficial microorganisms could increase the risk of sexually transmitted infections. Emerging therapies involve mucosal, intranasal vaccines, which trigger systemic and mucosal immune responses, thus protecting against HPV-induced tumours.
  • 2.4K
  • 18 Oct 2022
Topic Review
Indian Escorts in Dubai: An Overview
However, it’s important to note that escort services in Dubai, particularly those involving Indian women. The presence of Indian escorts in Dubai is a topic that draws attention, particularly due to the unique cultural and legal landscape of the United Arab Emirates (UAE). While escort services exist in many parts of the world, Dubai, as a city that blends tradition with modernity, presents a complex scenario when it comes to the discussion of such services.
  • 2.4K
  • 07 May 2026
Topic Review
Polymer-Based Materials for Space Radiation Shielding
Space exploration requires the use of suitable materials to protect astronauts and spacecraft components (e.g. onboard electronics) from the hazardous effects of radiation, in particular, ionizing radiation, which is ubiquitous in the hostile space environment. In this scenario, polymer-based materials and composites play a crucial role in achieving effective radiation shielding while providing low-weight and tailored mechanical properties to different types of spacecraft elements.
  • 2.4K
  • 21 Mar 2024
Topic Review
Foams in Wastewater Treatment Plants
The formation of persistent foams can be a critical problem in wastewater treatment plants (WWTPs) as it could lead to a series of operational problems, especially the reduction of the overall system performance. To date, the effects of foaming in the WWTPs are a problem that is currently very common and shared, but which to date is treated mainly only at the management level and still too little studied through a globally shared scientific method: the complexity of the phenomenon and the systems have led to numerous partially contradictory descriptions and hypotheses over the years. The goal must be to suggest future research directions and indicate promising strategies to prevent or control the formation of foams in WWTPs. This study examines and investigates the problem of foams by a methodological approach of research through a review on the state of the art: the factors influencing the formation of foams are described first (such as surfactants and/or extracellular polymeric substances (EPSs)), then the known methods for the evaluation of foaming, both direct and indirect, are presented, with the aim of identifying the correct and best (from the management point of view) control and/or prevention strategies to be applied in the future in WWTPs.
  • 2.4K
  • 28 Oct 2020
Topic Review
Therapeutic Monoclonal Antibodies
Therapeutic monoclonal antibodies (mAbs) target specifically antigens and have proven their efficacy in many human diseases, especially autoimmune diseases (rheumatoid arthritis, lupus, psoriasis, inflammatory bowel diseases), cancers (breast, lung, colorectal, and hematological cancers). Their humanization has greatly enhanced their biocompatibility and decreased their side effects such as immunogenicity. The clinical success of mAbs has expanded their application domain to other pathologies such as infectious, migraine, asthma, and hereditary diseases.
  • 2.4K
  • 18 Jan 2021
Topic Review
Impact of Backpacks on Ergonomics
Among load carriage systems, the backpack (BP) is certainly one of the most widespread in the world, with tens of million people using them every day for shorter or longer periods since early childhood. The effects of load carriage packs on human gait biomechanics, physiology and metabolism depend on the weight carried, the design of the pack and its interaction with the user. 
  • 2.4K
  • 20 Jun 2022
Topic Review
Digital Transformation for Higher Education in South Africa
COVID-19 has left an unmistakable impression on the world stage. It has altered the global socio-economic landscape, forcing individuals to adapt and embrace new ways of doing business, as well as new ways of life. One of the most significant effects of the pandemic was to hasten the adoption of digital technologies by many areas of the global economy. Campus closures were observed in the higher education sector, putting an end to long-standing face-to-face teaching and learning. This necessitated the most rapid paradigm shift ever seen in this industry to continue educating and learning. An abrupt change to online learning, which is primarily reliant on digital technologies, occurred.
  • 2.4K
  • 18 Jul 2022
Topic Review
Creationist Cosmologies
Creationist cosmologies are explanations of the origins and form of the universe in terms of the Genesis creation narrative (Genesis 1), according to which God created the cosmos in eight creative acts over the Hexameron, six days of the "creation week": Young Earth creationists interpret the six days as six 24-hour periods; old Earth creationists allow for millions or even billions of years within the "creation week". Both regard the Genesis story as history, although some old earth creationists do not conflate the creation of the Earth and the universe, (i.e. they do not hold that the two are equally old and were created together). Creationist cosmologies differ significantly from scientific cosmology. According to scientific consensus, creationism lacks empirical support, cannot be meaningfully tested, and is not science.
  • 2.4K
  • 17 Oct 2022
Topic Review
Degrowth
Degrowth (French: décroissance) is a political, economic, and social movement based on ecological economics, anti-consumerist and anti-capitalist ideas. It is also considered an essential economic strategy responding to the limits-to-growth dilemma (see The Path to Degrowth in Overdeveloped Countries and post-growth). Degrowth thinkers and activists advocate for the downscaling of production and consumption—the contraction of economies—arguing that overconsumption lies at the root of long term environmental issues and social inequalities. Key to the concept of degrowth is that reducing consumption does not require individual martyring or a decrease in well-being. Rather, "degrowthers" aim to maximize happiness and well-being through non-consumptive means—sharing work, consuming less, while devoting more time to art, music, family, nature, culture and community.
  • 2.4K
  • 24 Nov 2022
Topic Review
Public Policy Implementation for Rural Development
Rural development is a problem of social and economic nature, which is required to be addressed in a manner taking into account its complexity. This development is related to planning and policy actions which central problem is (Ackoff 1977) how to make the proposed planning solutions accepted and implemented effectively. In rural context, this means to deal with a set of stakeholders with different education levels, purposes and influences, and with a set of standards which is lower than that of urban or national development.
  • 2.4K
  • 24 Jan 2024
Topic Review
Pyrrolizidine Alkaloids
Pyrrolizidine alkaloids (PAs) are a group of natural compounds that are present in several plant families, among which the most predominant are Boraginaceae, Asteraceae, and Fabaceae, and are produced as a defense response against herbivores. PAs are known for their toxicity and for posing an elevated risk to human and animal health when consumed in large quantities over long periods of time.
  • 2.4K
  • 08 Feb 2024
Topic Review
Giant Panda
The Giant Panda (Ailuropoda melanoleuca) is an iconic and beloved bear species native to the mountainous bamboo forests of central China. Renowned for its distinctive black-and-white fur markings and endearing appearance, the Giant Panda is a symbol of conservation efforts worldwide. Despite being classified as a carnivore, the Giant Panda's diet is predominantly herbivorous, consisting almost entirely of bamboo shoots and leaves.
  • 2.4K
  • 28 Feb 2024
Topic Review
Structural Health Monitoring Systems
Structural health monitoring (SHM) is a rapidly evolving field, and there is a vast literature covering several topics that are related to this field. This entry is focused on the analysis of the state of the art of sensors for guided ultrasonic waves for the detection and localization of impacts for structural health monitoring (SHM).
  • 2.4K
  • 06 May 2021
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