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Topic Review
Egyptian Six-Rowed Barley (Hordeum vulgare L.)
Barley (Hordeum vulgare L.) is one of the main and oldest cereal crops on Earth. Worldwide, its grain production is ranked fourth after maize, rice, and wheat. Barley is generally considered a poor man’s crop because it is easy to cultivate, with few requirements, and has a high capacity for adaptation to harsh environments. Some literature estimates the age of barley at 11,000 years. However, six-rowed barley did not arise until after 6000 BC. Archaeological evidence has dated barley cultivation to 5000–6000 BC in Egypt. Barley products, especially bread and beer, comprised a complete diet in ancient Egypt.
  • 3.2K
  • 11 Dec 2021
Topic Review
MAPK/ERK Dysfunction in Neurodegenerative Diseases
The signaling pathway of the microtubule-associated protein kinase or extracellular regulated kinase (MAPK/ERK) is a common mechanism of extracellular information transduction from extracellular stimuli to the intracellular space. The transduction of information leads to changes in the ongoing metabolic pathways and the modification of gene expression patterns. In the central nervous system, ERK is expressed ubiquitously, both temporally and spatially. The MAP-ERK pathway is a key element of the neuroinflammatory pathway triggered by glial cells during the development of neurodegenerative diseases, such as Parkinson’s and Alzheimer’s disease, Huntington’s disease, and amyotrophic lateral sclerosis, as well as prionic diseases. The process triggered by MAPK/ERK activation depends on the stage of development (mature or senescence), the type of cellular element in which the pathway is activated, and the anatomic neural structure. However, extensive gaps exist with regards to the targets of the phosphorylated ERK in many of these processes.
  • 3.2K
  • 31 Jan 2021
Biography
Murray Bookchin
Murray Bookchin (January 14, 1921 – July 30, 2006)[1] was an United States social theorist, author, orator, historian, and political philosopher. A pioneer in the ecology movement,[2] Bookchin formulated and developed the theory of social ecology and urban planning, within anarchist, libertarian socialist, and ecological thought. He was the author of two dozen books covering topics in politics
  • 3.2K
  • 30 Dec 2022
Topic Review
Diabetic Ketoacidosis Management in Special Population
Diabetic ketoacidosis (DKA) is characterized by uncontrolled hyperglycemia (>250 mg/dL), metabolic acidosis, and increased ketone concentration. DKA incidence increased at annual rate of 6.3% most notably in persons aged <45 years with significant increase in hospitalization rate between 2008 and 2018. Nevertheless, overall in-hospital mortality rates declined during the study period from 1.1% to 0.4%. DKA is a life-threatening, but preventable complication of type-1 diabetes with a thirty percent of the cases that could be attributed to type-2 diabetes. The major clinical difference between these two types of diabetes is a lesser degree of acidosis and absence of hyperkalemia in type 2 diabetes.
  • 3.2K
  • 20 Dec 2022
Topic Review
Bayesian Mindsponge Framework
Bayesian Mindsponge Framework (BMF, also known as Bayesian Mindsponge analytical approach) is an analytical approach that employs the mindsponge information-processing mechanism and Bayesian analysis (e.g., bayesvl package) as each other’s complement to conduct cognitive and psychological research. 
  • 3.2K
  • 19 Mar 2022
Topic Review
Book of Dzyan
The Book of Dzyan (comprising the Stanzas of Dzyan) is a reputedly ancient text of Tibetan origin. The Stanzas formed the basis for The Secret Doctrine (1888), one of the foundational works of the theosophical movement, by Helena Petrovna Blavatsky.
  • 3.2K
  • 21 Nov 2022
Topic Review
Mechanisms of Antibiotic Resistance
Bacteria can exhibit two types of antibiotic resistance: intrinsic and acquired. While intrinsic resistance is determined by naturally occurring mechanisms conferred by inherent structural and/or functional features of the bacteria, the acquired resistance results from the changes in the bacterial genome. These consist of mutations in antibiotic-targeted genes or the acquisition of exogenous DNA conferring resistance, horizontally transferred by plasmids, bacteriophages, transposons, or other mobile genetic elements. Many independent mechanisms of bacterial resistance to antibiotics have been identified, including primarily modification of the antibiotic target, changes in the cell envelope’s permeability, active pumping of the antibiotic out of the cell (so-called efflux system), and enzymatic inactivation.
  • 3.2K
  • 25 Apr 2023
Topic Review
Bit Manipulation Instruction Sets
Bit Manipulation Instructions Sets (BMI sets) are extensions to the x86 instruction set architecture for microprocessors from Intel and AMD. The purpose of these instruction sets is to improve the speed of bit manipulation. All the instructions in these sets are non-SIMD and operate only on general-purpose registers. There are two sets published by Intel: BMI (here referred to as BMI1) and BMI2; they were both introduced with the Haswell microarchitecture. Another two sets were published by AMD: ABM (Advanced Bit Manipulation, which is also a subset of SSE4a implemented by Intel as part of SSE4.2 and BMI1), and TBM (Trailing Bit Manipulation, an extension introduced with Piledriver-based processors as an extension to BMI1, but dropped again in Zen-based processors).
  • 3.2K
  • 17 Oct 2022
Topic Review
Strategy (Game Theory)
In game theory, a player's strategy is any of the options which they choose in a setting where the outcome depends not only on their own actions but on the actions of others. The discipline mainly concerns the action of a player in a game affecting the behavior or actions of other players. Some examples of "games" include chess, bridge, poker, monopoly, diplomacy or battleship. A player's strategy will determine the action which the player will take at any stage of the game. In studying game theory, economists enlist a more rational lens in analyzing decisions rather than the psychological or sociological perspectives taken when analyzing relationships between decisions of two or more parties in different disciplines. The strategy concept is sometimes (wrongly) confused with that of a move. A move is an action taken by a player at some point during the play of a game (e.g., in chess, moving white's Bishop a2 to b3). A strategy on the other hand is a complete algorithm for playing the game, telling a player what to do for every possible situation throughout the game. It is helpful to think about a "strategy" as a list of directions, and a "move" as a single turn on the list of directions itself. This strategy is based on the payoff or outcome of each action. The goal of each agent is to consider their payoff based on a competitors action. For example, competitor A can assume competitor B enters the market. From there, Competitor A compares the payoffs they receive by entering and not entering. The next step is to assume Competitor B doesn't enter and then consider which payoff is better based on if Competitor A chooses to enter or not enter. This technique can identify dominant strategies where a player can identify an action that they can take no matter what the competitor does to try and maximize the payoff. This also helps players to identify Nash equilibrium which are discussed in more detail below. A strategy profile (sometimes called a strategy combination) is a set of strategies for all players which fully specifies all actions in a game. A strategy profile must include one and only one strategy for every player.
  • 3.2K
  • 28 Nov 2022
Topic Review
Chelating Agents in Soil Remediation
The Fenton process is an efficient treatment for removing many organics pollutants in aqueous systems at acidic pH (2.8-3.5). However, the in-situ application of this technology for soil remediation (where pHs around neutrality are required) presents important limitations, such as catalyst (iron) availability and oxidant (H2O2) stability. The addition of chelating agents (CAs) makes iron soluble at circumneutral pH by forming complexes with Fe, and thus, enabling Fenton reactions under these conditions. This strategy, called chelate-modified Fenton process (MF), can be employed to overcome the challenges identified in conventional Fenton.
  • 3.2K
  • 09 Aug 2021
Topic Review
Liquid Crystal Elastomers and LCE-Based Composite Material
Liquid crystal elastomers (LCEs) are programmable deformable materials that can respond to physical fields such as light, heat, and electricity. Photothermal-driven LCE has the advantages of accuracy and remote control and avoids the requirement of high photon energy for photochemistry. An indispensable part of photothermally driven LCEs materials are photothermal materials.
  • 3.2K
  • 14 Jul 2022
Topic Review
Police Vehicles in Belgium
Before 2001, there were several police forces in Belgium: After the reform of 2001, there are only two police forces:
  • 3.2K
  • 18 Oct 2022
Topic Review
Armoured Vehicle Royal Engineers
Armoured Vehicle Royal Engineers (AVRE), also known as Assault Vehicle Royal Engineers is the title given to a series of armoured military engineering vehicles operated by the Royal Engineers (RE) for the purpose of protecting engineers during frontline battlefield operations. In protecting engineers, the vehicles also became a mobile platform for a variety of engineering purposes, mounting large calibre weapons for demolition, carrying engineering stores, mine clearance explosives, a variety of deployable roadways, and modified engineering bridges for gaps that the related Armoured Ramp Carrier ("ARK") vehicles could not overcome.
  • 3.2K
  • 28 Oct 2022
Topic Review
Sleep Paralysis and Lucid Dreaming
Sleep paralysis and lucid dreams are two states of consciousness that are connected to rapid eye movement (REM) sleep but are defined by higher awareness in contrast to regular REM sleep. Despite these similarities, the two states differ widely in their emotional tone and their perceived controllability.
  • 3.2K
  • 23 May 2023
Topic Review
Tumor Spheroids and Organoids
Understanding and investigating tumors is carried out by researchers using a number of different methods. One exciting and promising area is 3D tumor models including spheriod and organoid models. They act in similar ways to tumors which means we can use them to gather important information. This ranges from the way tumors react through to how different treatments may work on tumors. Ultimately they may help guide us towards the types of drugs and therapies that could be used to treat tumors. This work gives an overview of these technologies, the types of 3D models available and how they can be used to improve treatments and their applications in personalized medicine. 
  • 3.2K
  • 26 Oct 2020
Topic Review
Lazarus (IDE)
Lazarus is a free cross-platform visual integrated development environment (IDE) for rapid application development (RAD) using the Free Pascal compiler. Its goal is to provide an easy-to-use development environment for programmers developing with the Pascal Object language, which is as close as possible to Delphi. Software developers use Lazarus to create native-code console and graphical user interface (GUI) applications for the desktop, and also for mobile devices, web applications, web services, visual components and function libraries for a number of different platforms, including Mac, Linux and Windows. An application created using Lazarus on one platform can generally compile and execute on any platform for which a Free Pascal compiler exists. For desktop applications a single source can target Mac, Linux, and Windows, with little or no modification. An example is the Lazarus IDE itself, created from a single code base and available on all major platforms including the Raspberry Pi.
  • 3.2K
  • 30 Sep 2022
Topic Review
Windows 9X
Windows 9x is a generic term referring to a series of Microsoft Windows computer operating systems produced from 1995 to 2000, which were based on the Windows 95 kernel and its underlying foundation of MS-DOS, both of which were updated in subsequent versions. The first version in the 9x series was Windows 95, which was succeeded by Windows 98 and then Windows Me, which was the third and last version of Windows on the 9x line, until the series was superseded by Windows XP. Windows 9x is predominantly known for its use in home desktops. In 1998, Windows made up 82% of operating system market share. Internal release versions for versions of Windows 9x are 4.x. The internal versions for Windows 95, 98, and Me are 4.0, 4.1, and 4.9, respectively. Previous MS-DOS-based versions of Windows used version numbers of 3.2 or lower. Windows NT, which was aimed at professional users such as networks and businesses, used a similar but separate version number between 3.1 and 4.0. All versions of Windows from Windows XP onwards are based on the Windows NT codebase.
  • 3.2K
  • 30 Nov 2022
Topic Review
Project-Based Learning in the English Language
Project-Based Learning (PBL), or Problem-Based Learning, is a pedagogical strategy that has cultivated an interest in reading and enhancing English language comprehension. This approach is founded on the premise that students acquire knowledge and skills most effectively when engaged in meaningful and practical projects, as opposed to mere rote memorization.
  • 3.2K
  • 19 Jun 2023
Topic Review
Diospyros kaki L. (Persimmon)
Persimmon (Diospyros kaki L.) is a member of the Ebenaceae family and is a very popular and important fruit in East Asian countries, being widely produced in China, South Korea, and Japan. The name “persimmon” (Diospyros) originates from the Greek dióspuron, which means “food of Zeus”, while “kaki” comes from the Japanese kaki (柿).
  • 3.2K
  • 08 Oct 2021
Topic Review
The Role of Phytoplankton in Carbon Dioxide Fixation
Marine phytoplankton account for more than half of the carbon dioxide fixation of Earth. The export of carbon is highest at the photic zone of the ocean, which is dominated by phytoplankton. The term phytoplankton comes from the Greek words phyto (plants) and plankton (wanderers or drifters). Plankton can also be zooplanktons that feed on phytoplankton and release fecal pellets that are made of dissolved carbon particles.
  • 3.2K
  • 13 Apr 2022
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