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Topic Review
Baddeley's Model of Working Memory
Baddeley's model of working memory is a model of human memory proposed by Alan Baddeley and Graham Hitch in 1974, in an attempt to present a more accurate model of primary memory (often referred to as short-term memory). Working memory splits primary memory into multiple components, rather than considering it to be a single, unified construct. Baddeley & Hitch proposed their three-part working memory model as an alternative to the short-term store in Atkinson & Shiffrin's 'multi-store' memory model (1968). This model is later expanded upon by Baddeley and other co-workers to add a fourth component, and has become the dominant view in the field of working memory. However, alternative models are developing, providing a different perspective on the working memory system. The original model of Baddeley & Hitch was composed of three main components: the central executive which acts as a supervisory system and controls the flow of information from and to its slave systems: the phonological loop and the visuo-spatial sketchpad. The phonological loop stores verbal content, whereas the visuo-spatial sketchpad caters to visuo-spatial data. Both the slave systems only function as short-term storage centers. In 2000, Baddeley added a third slave system to his model, the episodic buffer. Baddeley & Hitch's argument for the distinction of two domain-specific slave systems in the older model was derived from experimental findings with dual-task paradigms. Performance of two simultaneous tasks requiring the use of two separate perceptual domains (i.e. a visual and a verbal task) is nearly as efficient as performance of the tasks individually. In contrast, when a person tries to carry out two tasks simultaneously that use the same perceptual domain, performance is less efficient than when performing the tasks individually. A fourth component of Baddeley's model was added 25 years later to complement the central executive system. The third slave system was designated as episodic buffer. It is considered a limited-capacity system that provides temporary storage of information by conjoining information from the subsidiary systems, and long-term memory, into a single episodic representation.
  • 4.0K
  • 04 Nov 2022
Topic Review
N-Butanol
n-Butanol or n-butyl alcohol or normal butanol is a primary alcohol with a 4-carbon structure and the chemical formula C4H9OH. Its isomers include isobutanol, 2-butanol, and tert-butanol. Butanol is one of the group of "fusel alcohols" (from the German for "bad liquor"), which have more than two carbon atoms and have significant solubility in water. n-Butanol occurs naturally as a minor product of the fermentation of sugars and other carbohydrates, and is present in many foods and beverages. It is also a permitted artificial flavorant in the United States, used in butter, cream, fruit, rum, whiskey, ice cream and ices, candy, baked goods and cordials. It is also used in a wide range of consumer products. The largest use of n-butanol is as an industrial intermediate, particularly for the manufacture of butyl acetate (itself an artificial flavorant and industrial solvent). It is a petrochemical, manufactured from propylene and usually used close to the point of manufacture. Estimated production figures for 1997 are: United States 784,000 tonnes; Western Europe 575,000 tonnes; Japan 225,000 tonnes.
  • 4.0K
  • 26 Oct 2022
Topic Review
Stoat
The Stoat (Mustela erminea), also known as the short-tailed weasel, is a small carnivorous mammal belonging to the Mustelidae family. Characterized by its slender body, short legs, and distinctive white winter coat with a black-tipped tail, the stoat is found in various habitats across North America, Europe, and Asia. As an agile predator, the stoat preys on a wide range of small mammals, birds, and insects, utilizing its keen senses and swift movements to hunt and capture its prey.
  • 4.0K
  • 15 Mar 2024
Topic Review
Capture Myopathy in Spotted Deer
Capture myopathy is a noninfectious disease of the muscle associated with capturing or handling of any animals.
  • 4.0K
  • 17 Jun 2021
Topic Review
Artificial Intelligence for Digital Heritage Innovation
Artificial intelligence (AI) is a game changer in many fields, including cultural heritage. It supports the planning and preservation of heritage sites and cities, enables the creation of virtual experiences to enrich cultural tourism and engagement, supports research, and increases access and understanding of heritage objects. Despite some impressive examples, the full potential of AI for economic, social, and cultural change is not yet fully visible.
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  • 27 Feb 2024
Topic Review
Intra-Articular Administration of Therapeutics for Joint Disorders
Several acute and chronic inflammatory diseases of the joints affect individuals. Intra-articular (IA) drug delivery is often preferred when the joint disease is severe and painful since it places high concentrations of the drug directly at the desired site. Researchers have reported different strategies for increasing the local retention of the intra-articularly administered medication. 
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  • 23 Nov 2022
Topic Review
The Impact of Regulatory Pressures on Governance
abstract: Purpose: With this paper, we aim to provide an insight on the regulatory reforms on corporate governance, brought about, by its ineffectiveness in the global financial crisis. Design/Approach/Methodology: To this effect we compared accounting ratios over a period of 10 years - 5 years prior and during financial crisis (i.e. 2006-2010) and 5-years post regulatory reforms on governance (i.e. 2014-2018) -using panel data of ratios for profitability, liquidity and efficiency. Findings: The general trend in the banks was that profitability and efficiency decreased drastically in the post regulatory period, contrary to liquidity, which increased, as higher capital buffers were imposed on banks. Practical Implications: This study is important because the burden of regulations is detrimental to the performance of public banks in the EU Mediterranean region. There are several arguments that the burden of compliance is becoming very costly and this is negatively affecting their profitability and efficiency. Originality/Value: These findings are of interest to economists and policymakers within the European Mediterranean region. Keywords: Governance, regulations on governance, changes in regulations, performance, financial crisis, governance and performance. JEL code: G21, G28.
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  • 28 May 2020
Topic Review
Smart City Applications
Smart city applications are designed to take advantage of the smart city ICT and collected data to provide value-added smart features. These applications use data analytics, intelligent techniques and other advanced technologies to make smart decisions that improve the smart city's operations and quality of life.
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  • 17 Dec 2021
Topic Review
Ballast Contamination Mechanisms
Ballasted railway tracks constitute the major transportation grids in many countries across the globe; they convey commuters, as well as freight and bulk cargoes, between cities, mines, farmlands, and ports . The railtrack structure can be categorised into two groups: the substructure and the superstructure. The substructure comprises the subgrade, the sub-ballast, and the ballast, while the superstructure encompasses the sleepers (timber or concrete), the fastening mechanism, and the steel rails.
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  • 14 Jan 2021
Topic Review
Plants as anti-inflammatory drugs
Plants represent the main source of molecules for the development of new drugs, which intensifies the interest of transnational industries in searching for substances obtained from plant sources, especially since the vast majority of species have not yet been studied chemically or biologically, particularly concerning anti-inflammatory action. Anti-inflammatory drugs can interfere in the pathophysiological process of inflammation, to minimize tissue damage and provide greater comfort to the patient. Therefore, it is important to note that due to the existence of a large number of species available for research, the successful development of new naturally occurring anti-inflammatory drugs depends mainly on a multidisciplinary effort to find new molecules. Although many review articles have been published in this regard, the majority presented the subject from a limited regional perspective.
  • 4.0K
  • 25 Aug 2020
Topic Review
Family Tree of the Malaysian Monarchs
The following is a family tree of the monarchs of Malaysia.   - - - -   The dashed line denotes a marriage     ♀   - denotes a female.
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  • 11 Nov 2022
Topic Review
Introduction to the Metric System
The metric system was developed during the French Revolution to replace the various measures previously used in France. The metre (spelled "meter" in American English) is the unit of length in the metric system and was originally based on the dimensions of the earth, as far as it could be measured at the time. The litre (or in American English "liter"), is the unit of volume and was defined as one thousandth of a cubic metre. The metric unit of mass is the kilogram and it was defined as the mass of one litre of water. The metric system was, in the words of French philosopher Marquis de Condorcet, "for all people for all time". The metric system has names to cover different ranges of the same measure. Instead of using names based on the context of the measure, the metric system mainly uses names made by adding prefixes, such as kilo- or milli-, as decimal multipliers to the base unit names. Thus, one kilogram is 1000 grams and one kilometre is 1000 metres. During the nineteenth century the metric system was adopted by both the worldwide scientific community and many countries as the system of measurement. It therefore became truly international. Until 1875 the French government owned the prototype metre and kilogram, but in that year the Convention of the metre was signed and control of the standards relating to mass and length passed on to a trio of inter-government organisations. In 1960 the metric system was extensively revised to form the International System of Units, abbreviated to "SI".
  • 4.0K
  • 23 Nov 2022
Topic Review
Ionizing Radiation
The development of protective agents against harmful radiations has been a subject of investigation for decades. However, effective (ideal) radioprotectors and radiomitigators remain an unsolved problem. Because ionizing radiation-induced cellular damage is primarily attributed to free radicals, radical scavengers are promising as potential radioprotectors. Early development of such agents focused on thiol synthetic compounds, e.g., amifostine (2-(3-aminopropylamino) ethylsulfanylphosphonic acid), approved as a radioprotector by the Food and Drug Administration (FDA, USA) but for limited clinical indications and not for nonclinical uses. To date, no new chemical entity has been approved by the FDA as a radiation countermeasure for acute radiation syndrome (ARS). All FDA-approved radiation countermeasures (filgrastim, a recombinant DNA form of the naturally occurring granulocyte colony-stimulating factor, G-CSF; pegfilgrastim, a PEGylated form of the recombinant human G-CSF; sargramostim, a recombinant granulocyte macrophage colony-stimulating factor, GM-CSF) are classified as radiomitigators. No radioprotector that can be administered prior to exposure has been approved for ARS. This differentiates radioprotectors (reduce direct damage caused by radiation) and radiomitigators (minimize toxicity even after radiation has been delivered). Molecules under development with the aim of reaching clinical practice and other nonclinical applications are discussed. Assays to evaluate the biological effects of ionizing radiations are also analyzed. Ionizing radiation is the energy released by atoms in the form of electromagnetic waves (e.g., X or gamma rays) or particle radiation (alpha, beta, electrons, protons, neutrons, mesons, prions, and heavy ions) with sufficient energy to ionize atoms or molecules.
  • 4.0K
  • 23 Feb 2022
Topic Review
Tissue
In biology, tissue is a biological organizational level between cells and a complete organ. A tissue is an ensemble of similar cells and their extracellular matrix from the same origin that together carry out a specific function. Organs are then formed by the functional grouping together of multiple tissues. The English word "tissue" derives from the French word "tissu", the past participle of the verb tisser, "to weave". The study of tissues is known as histology or, in connection with disease, as histopathology. Xavier Bichat is considered as the "Father of Histology". Plant histology is studied in both plant anatomy and physiology. The classical tools for studying tissues are the paraffin block in which tissue is embedded and then sectioned, the histological stain, and the optical microscope. Developments in electron microscopy, immunofluorescence, and the use of frozen tissue-sections have enhanced the detail that can be observed in tissues. With these tools, the classical appearances of tissues can be examined in health and disease, enabling considerable refinement of medical diagnosis and prognosis.
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  • 26 Oct 2022
Topic Review
List of Russian Saints
This list of Russian saints includes the saints canonized by the Russian Orthodox Church and the Russian saints canonized by other Orthodox Churches. Saints are sorted by their first names. A more complete list of saints: List of Russian saints (until 15th century) List of Russian saints (since 15th century)
  • 4.0K
  • 28 Nov 2022
Topic Review Peer Reviewed
The Capital Asset Pricing Model
The capital asset pricing model (CAPM) is an influential paradigm in financial risk management. It formalizes mean-variance optimization of a risky portfolio given the presence of a risk-free investment such as short-term government bonds. The CAPM defines the price of financial assets according to the premium demanded by investors for bearing excess risk.
  • 4.0K
  • 13 Apr 2022
Topic Review
GeForce 8 Series
The GeForce 8 series is the eighth generation of Nvidia's GeForce line of graphics processing units. The third major GPU architecture developed by Nvidia, Tesla represents the company's first unified shader architecture.
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  • 26 Oct 2022
Topic Review
Inflammatory Pain Study in Animal-Models
Pain is an easily recognized sensation that is experienced by humans and animals alike. However, the process behind the production of the pain experience is a complex pathway that requires parallel integration of both the emotional and sensory experiences together with noxious perceptual information registered by multiple layers of our brain structure with the purpose of defending our body from harm’s way. Here, the complete protocol that is being adapted for inflammatory pain study in animals induced by different phlogogenic agents and different assessment methods were elaborated along with the underlying mechanism of actions. This provides a concise idea and improves our scientists’ understanding of inflammatory pain management in future research.
  • 4.0K
  • 05 Nov 2020
Topic Review
Bioactive Glass
Bioactive glass (BAG) consist of known biocompatible and bioactive minerals, including fluorapatite (FAP), wollastonite, diopside, and tricalcium phosphate. A bioactive material can interact with the biological environment to elicit a specific biological response and they can be osteoconductive or osteoinductive. Bioactive Glasses are amorphous solids with the irregular organization of atoms, optically transparent, and brittle consisting of silica networks. They possesses bioactivity and antimicrobial properties as presented n following sections. The bioactivity of BAGs involves several steps; BAGs immediately undergo ionic dissolution and glass degradation via the exchange of H+ ions in the solution and Na+ and Ca2+ from the glass network. BAG exhibits antimicrobial properties against various pathogens, e.g pathogens associated with sinusitis and osteomyelitis.
  • 4.0K
  • 22 Oct 2020
Topic Review
Graphene Oxide-Based Anticorrosive Coatings
Graphene oxide was extensively used in the last few years due to its remarkable assets and proved to have a significant contribution to composite materials. Concerning the graphene-based coatings, the synthesis methods, protective function, anticorrosion mechanism, feasible problems, and some methods to improve the overall properties were highlighted. Regarding the contribution of the nanostructure used to improve the capability of the material, several modification strategies for graphene oxide along with the synergistic effect exhibited when functionalized with other compounds were mainly discussed.
  • 4.0K
  • 10 Dec 2020
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