Topic Review
Emerging and Re-Emerging Viruses
Emerging and re-emerging viral outbreaks are becoming more frequent due to increased international travel and global warming. These viral outbreaks impose serious public health threats and have transformed national strategies for pandemic preparedness with global economic consequences. At the molecular level, viral mutations and variations are constantly thwarting vaccine efficacy, as well as diagnostic, therapeutic, and prevention strategies.
  • 385
  • 01 Nov 2023
Topic Review
Syndromic Surveillance Systems for Mass Gatherings
As defined by the Centers for Disease Control and Prevention (CDC), public health surveillance is the “ongoing systematic collection, analysis, and interpretation of outcome-specific data for use in the planning, implementation, and evaluation of public health practice,” which has been instrumental in the reduction in mortality from exposure to infectious diseases and environmental toxins. The arm of public health surveillance that deals specifically with the early detection of disease outbreaks or clusters of adverse health emergencies is referred to as syndromic surveillance and can be defined as “an investigational approach where health department staff, assisted by automated data acquisition and generation of statistical alerts, monitor disease indicators in real-time or near-real-time to detect outbreaks of disease earlier than would otherwise be possible with traditional public health methods”.
  • 384
  • 22 Apr 2022
Topic Review
Farm Biosecurity and Antimicrobial Usage in Food Animals
With the limited alternatives for antimicrobials, farm biosecurity (and herd management) is considered a promising tool to mitigate the non-judicious AMU and to maintain animal health, production, and welfare.
  • 379
  • 25 May 2023
Topic Review
Mucociliary Clearance and SARS-CoV-2 Infection
Ciliary beat frequency (CBF) within the ciliated epithelium of the nasal tract can be stimulated to a higher frequency and provide increased protection against transient exposure to airway irritants. Smokers as well as non-smokers exposed to secondhand tobacco smoke were found to have higher CBFs. However, with extended exposure to irritants, persistent upregulated CBF can damage and remodel the epithelial layer with fewer protective cilia. Additionally, mucociliary clearance (MCC), the innate defense mechanism of the respiratory system, traps particles and pathogens within the mucous layer of the epithelium and propels them out of the airways through ciliary activity. However, this mechanism becomes defective as disease progresses, increasing susceptibility to viral respiratory infections. 
  • 379
  • 14 Mar 2024
Topic Review
Genetic Polymorphisms as Biomarkers of Susceptibility
A clean environment is fundamental to human health and well-being. However, environment can be a souce of  various stressors, such as bad quality of air, pollution, noise and hazardous substances affecting our health.The human health is also influenced by climate change, producing flood, heatwaves and presence of vector-borne disease affecting the global health. The climate changes, loss of biodiversity loss and land degradation contribute to impact the human well-being. Human health is influenced by various factors; these include genetic inheritance, behavioral lifestyle, socioeconomic and environmental conditions, and public access to care and therapies in case of illness, with the support of the national health system. All these factors represent the starting point for the prevention and promotion of a healthy lifestyle. However, it is not clear to what extent these factors may actually affect the health of an entire population. The exposures to environmental and occupational factors are several, most of which might be poorly known, contributing to influencing the individual health. Personal habits, including diet, smoking, alcohol, and drug consumption, together with unhealthy behaviors, may inevitably lead people to the development of chronic diseases, contributing to increase aging and decrease daily life expectancy. Despite such risks, humans should modify the bad habits in favour of virtuous habits. 
  • 377
  • 19 Jan 2023
Topic Review
Health Effects of POPs In South Korea
Persistent organic pollutants (POPs) usually originate from human activities and have been released into the environment for several decades. They are highly resistant to natural decomposition and can accumulate in an organism’s tissues and in all environmental components. Due to their unique characteristics, they have an ability to bio-magnify and bio-accumulate in animals, through the food chain and via inhalation, severely endangering the health of people. As reported, the exposure of humans to POPs causes various health problems such as cancers, diabetes, birth defects, endocrine disruption, cardiovascular diseases and dysfunctional immune and reproductive systems. 
  • 374
  • 24 Jul 2023
Topic Review
Factors Associated with HIV and Syphilis Co-Infection
Human immunodeficiency virus (HIV)–syphilis co-infection poses a threat to certain populations, and patients may have considerably poorer health outcomes due to these infections. Males—particularly men who have sex with men—compose the overwhelming majority of co-infected cases. Additional risk factors include a low CD4 cell count, current or past sexually transmitted infections, and a high number of sexual partners. 
  • 373
  • 27 May 2022
Topic Review
Public Health Concerns Related to Pesticide Exposure
One of the major issues related to food safety is the lack of globally harmonized pesticide legislation and safety standards. Pesticide maximum residue levels (MRLs) in foods and feeds significantly differ, especially among developed and developing countries. The differences in regulations also cause trade issues since many developing countries use unauthorized pesticides or different MRLs.
  • 373
  • 04 Aug 2023
Topic Review
The Emergence of SARS-CoV-2 Variants
The emergence of new variants of Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) associated with varying infectivity, pathogenicity, diagnosis, and effectiveness against treatments challenged the overall management of the coronavirus disease 2019 (COVID-19) pandemic. 
  • 368
  • 21 Mar 2023
Topic Review
The Complex Causes of Breast Cancer Disparities
Racial disparities in breast cancer present a vexing and complex challenge for public health. A diverse array of factors contributes to disparities in breast cancer incidence and outcomes, and, thus far, efforts to improve racial equity have yielded mixed results. Systems theory offers a model that is well-suited to addressing complex issues. In particular, the concept of a systemic leverage point offers a clue that may assist researchers, policymakers, and interventionists in formulating innovative and comprehensive approaches to eliminating racial disparities in breast cancer. 
  • 367
  • 04 Jan 2024
Topic Review
Multiple Sclerosis and Sodium Toxicity
Salt intake is associated with multiple sclerosis; however, controversial findings that challenge this association rely primarily on methods that do not measure total sodium storage within the body, such as food surveys and urinary sodium excretion. In contrast, tissue sodium concentrations measured with sodium MRI confirm high sodium levels in multiple sclerosis, suggesting a role for sodium toxicity as a risk factor for the disease.
  • 365
  • 14 Mar 2024
Topic Review
Impact of COVID-19 on Mental Health in Adolescents
Globally, adolescents of varying backgrounds experience higher rates of anxiety, depression, and stress due to the pandemic. Secondly, adolescents also have a higher frequency of using alcohol and cannabis during the COVID-19 pandemic. However, social support, positive coping skills, home quarantining, and parent–child discussions seem to positively impact adolescent mental health during this period of crisis. Whether in the United States or abroad, the COVID-19 pandemic has impacted adolescent mental health. Therefore, it is important to seek and to use all of the available resources and therapies to help adolescents mediate the adjustments caused by the pandemic.
  • 362
  • 13 Feb 2023
Topic Review
Health Department Planning Actions for Climate Change
Public health departments are on the frontlines of protecting vulnerable groups and working to eliminate health disparities through prevention interventions, disease surveillance and community education. Exploration of the roles national, state and local health departments (LHDs) play in advancing climate change planning and actions to protect public health is a developing arena of research.
  • 360
  • 21 Jul 2022
Topic Review
Children with Attention Deficit Hyperactivity Disorder
Children with attention deficit hyperactivity disorder are characterized by inattention, hyperactivity, impulsivity, difficulty in controlling behavior, or such comprehensive symptoms, while children with ASD have apparent deficits in social communication skills and repetitive stereotyped behavior patterns. Despite significant differences in the core symptoms between children with ADHD and ASD, clinical studies have supported the similarity of the behavioral disorders, and the findings suggest that the two types of children not only have highly shared heritability, but also represent the performance of the same endophenotype and can be classified into the same diagnostic entity.
  • 360
  • 03 Apr 2023
Topic Review
Lifestyle and Insulin Resistance
Insulin resistance is a metabolic disorder and it is defined as the inability of a known quantity of insulin (exogenous or endogenous) to increase glucose uptake and utilization in an individual as much as it does in the healthy population.
  • 359
  • 16 Jan 2023
Topic Review
Human Behavior in Plasmodium knowlesi Malaria Infection
P. knowlesi is a zoonotic disease transmitted by the Anopheles mosquito, which harbors the Plasmodium parasite. Previously, the disease was believed to occur only among the Macaca fascicularis and M. nemestrina monkeys, found largely in southeast Asia.
  • 358
  • 02 Apr 2022
Topic Review
Effects of High-Altitude Mountaineering on Mountaineers
Nowadays, with the convenience of international traveling and driven by many individuals’ fond dreams of challenging high-altitude exercises, high-altitude mountaineering is becoming increasingly popular worldwide. Therefore, researchers performed a meta-analysis to determine the effects of high-altitude mountaineering on cognitive functions in mountaineers before and after climbing.
  • 357
  • 04 May 2023
Topic Review
Influence of Probiotics on Depressive Disorders
Depressive disorders have a major impact on occupational health and are costly to the economy and the healthcare system. Probiotics are live, non-pathogenic micro-organisms that, when ingested in adequate amounts, can colonize the intestinal tract and confer health benefits on the patient. Numerous studies have described the potential usefulness of certain probiotic strains in the treatment and prevention of depressive disorders, with differing results.
  • 354
  • 31 Aug 2023
Topic Review
Hypertension, Anxiety and Obstructive Sleep Apnea
Increased anxiety in these conditions may be linked to a high-salt diet through stimulation of the sympathetic nervous system, which increases blood pressure while releasing catecholamines, causing a “fight or flight” response. A rostral shift of fluid overload from the lower to the upper body occurs in obstructive sleep apnea associated with COVID-19 and cardiovascular disease, and may be related to sodium and fluid retention triggered by hypertonic dehydration. Chronic activation of the renin-angiotensin-aldosterone system responds to salt-induced dehydration by increasing reabsorption of sodium and fluid, potentially exacerbating fluid overload. Anxiety may also be related to angiotensin II that stimulates the sympathetic nervous system to release catecholamines. 
  • 353
  • 14 Mar 2024
Topic Review
The African Wastewater Resistome
In Africa, the prevalence of Antimicrobial Resistance (AMR)  in wastewater is of particular concern due to the inadequate sanitation and wastewater treatment facilities, coupled with the overuse and misuse of antibiotics in healthcare and agriculture. 
  • 351
  • 10 May 2023
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