Your browser does not fully support modern features. Please upgrade for a smoother experience.
Subject:
All Disciplines Arts & Humanities Biology & Life Sciences Business & Economics Chemistry & Materials Science Computer Science & Mathematics Engineering Environmental & Earth Sciences Medicine & Pharmacology Physical Sciences Public Health & Healthcare Social Sciences
Sort by:
Most Viewed Latest Alphabetical (A-Z) Alphabetical (Z-A)
Filter:
All Topic Review Biography Peer Reviewed Entry Video Entry
Topic Review
Effects of Magnetic Nanomaterials on Biological Neural signals
By sending electrical, optical, chemical, auditory, or magnetic stimuli to specific neural tissue, a process known as neuromodulation may be used to alter neuronal activity. Through active research efforts, the development of nanotechnology has recently revolutionized neuromodulation techniques. On the one hand, the adaptable nano-science toolbox promoted neuromodulation techniques that were previously associated with huge devices toward shrunk devices with soft mechanics, closely packed components, and long-lasting performance. The neurological issue may be seamlessly integrated with these nanoscale instruments due to their enhanced spatial resolution and precise targeting capabilities. In addition, magnetic nanoparticles represent a significant aspect of magnetic neuromodulation development. Deep brain stimulation is possible with the use of superparamagnetic nanoparticles, which can be delivered to the brain and controlled remotely. Additionally, by regulating certain ion channels, force-generating or heat-dissipating super-paramagnetic nanoparticles can be employed for wireless neuromodulation. Specific cells’ ion channels are targeted by taking advantage of their inherent functionality or via genetic modification. Magnetic nanoparticles’ magnetic forces activate mechanosensitive channels, such as TREK1 and Piezo1, and magnetic nanoparticles that produce heat in response to an external alternating magnetic field can activate heat-sensitive ion channels, such as TRPV1.
  • 1.1K
  • 30 Jan 2023
Topic Review
Implementation of Smart Retrofitting
Recovering old machinery, once it reaches its end of life, allows companies to be sustainable. Several strategies are available for this purpose, both from the point of view of hardware and software modifications. Especially in the industrial sector, these strategies are classified as revamping, remanufacturing and retrofitting. Machinery revamping, retrofitting and remanufacturing are all used to improve industrial equipment performance, efficiency and sustainability. Each approach has unique benefits and trade-offs, depending on the specific needs and requirements of the equipment and business. Moreover, according to Industry 4.0 principles, it is also possible to talk about smart retrofitting, involving the integration of various technologies such as sensors, automation systems, Digital Twins, artificial intelligence and data analytics software to control and optimise the operation of the machinery. Digital Twins, in particular, have been widely used among smart retrofit solutions and can integrate several innovative aspects of dated systems. 
  • 1.1K
  • 22 May 2023
Topic Review Peer Reviewed
A Systematic Review of Effects on ACL Injury of Soccer Shoe Outsoles, Soccer Playing Field Surfaces, and Outsole–Surface Interface
Soccer is a sport with a high incidence of injuries. The most common injury occurs when the anterior cruciate ligament of the knee has undergone a sprain, strain, or partial or total rupture. Besides fitness factors (e.g., proprioception, balance and strength capabilities), a principal cause of ACL injuries is sport shoes and playing surfaces. Especially with the emergence of artificial surfaces (rubbers, turfs, concrete, asphalt, red turf), the ACL injuries dramatically increase. The cost of ACL injuries is high both in terms of career termination and in social and economic costs. Thus, it is necessary to understand the impact of sport shoes and playing surfaces on the ACL and how it can be mitigated. The present literature review followed the PRISMA methodology to identify the major biomechanical factors influencing the behavior of surfaces and shoes in relation to the ACL damage. Fifty-eight papers were identified. After reviewing the mechanism of injuries, we identified several distinct factors: type of outsole and mechanical arrangement of the outsoles; shear forces; characteristics of artificial turf surfaces; effect of weather on artificial surface aging and change in mechanical characteristics; outsole/ground interface; and the frictional, tractional and rotational forces in the pathogenesis of ACL injuries in soccer.
  • 1.1K
  • 28 May 2024
Topic Review
Radeon 9000 Series
The R300 GPU, introduced in August 2002 and developed by ATI Technologies, is its third generation of GPU used in Radeon graphics cards. This GPU features 3D acceleration based upon Direct3D 9.0 and OpenGL 2.0, a major improvement in features and performance compared to the preceding R200 design. R300 was the first fully Direct3D 9-capable consumer graphics chip. The processors also include 2D GUI acceleration, video acceleration, and multiple display outputs. The first graphics cards using the R300 to be released were the Radeon 9700. It was the first time that ATI marketed its GPU as a Visual Processing Unit (VPU). R300 and its derivatives would form the basis for ATI's consumer and professional product lines for over 3 years.
  • 1.1K
  • 03 Nov 2022
Topic Review
Cardiotoxicity of Fluoropyrimidines
The definition of cardiotoxicity includes not only clinical symptoms but also changes in left ventricular ejection fraction or histopathological changes in cardiomyocytes. Cardiotoxicity is a rare but serious complication of cytostatic agents, defined as a negative impact on heart function or cardiac cells. Fluoropyrimidine cardiotoxicity was first described in 1969, and since then, many studies have confirmed these findings, but many details such as incidence, mechanisms, and treatment are unclear and remain disputed.
  • 1.1K
  • 20 Oct 2021
Topic Review
Stream Ecological Integrity
Streams and rivers provide important services to humans, and therefore, their ecological integrity should be a societal goal. Although ecological integrity encompasses structural and functional integrity, stream bioassessment rarely considers ecosystem functioning. Organic matter decomposition and ecosystem metabolism are prime candidate indicators of stream functional integrity.
  • 1.1K
  • 11 Jan 2021
Topic Review
Responsible Investment in Agriculture Principles and Food Systems
The Principles for Responsible Investment in Agriculture and Food Systems (CFS-RAI) are shown as suitable instruments to contribute to the Sustainable Development Goals (SDG) in rural areas. Local Action Groups (LAGs) have proven to be effective governance structures for the implementation and management of rural development projects based on participation and collective action. 
  • 1.1K
  • 13 Sep 2022
Topic Review
Treatment of Metastatic Uveal Melanoma
This work shows a global vision of the situation, placing the reader in a concise and orderly manner in perspective of the current state of treatment of metastatic uveal melanoma. Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. The most frequent location is the choroid, representing 80% of the total, followed by the ciliary body, 12%, and the iris, 8%. The incidence of UM ranges from 5.3 to 10.9 cases per million inhabitants per year. Risk factors for developing UM include fair skin, congenital ocular melanocytosis, melanocytoma, and BAP1-tumor predisposition syndrome.
  • 1.1K
  • 21 Oct 2020
Topic Review
MPL Gene
MPL proto-oncogene, thrombopoietin receptor
  • 1.1K
  • 23 Dec 2020
Topic Review
LDLR Gene
Low density lipoprotein receptor
  • 1.1K
  • 23 Dec 2020
Topic Review
Progressive Familial Heart Block
Progressive familial heart block is a genetic condition that alters the normal beating of the heart.
  • 1.1K
  • 24 Dec 2020
Topic Review
Retinitis Pigmentosa
Retinitis pigmentosa is a group of related eye disorders that cause progressive vision loss. These disorders affect the retina, which is the layer of light-sensitive tissue at the back of the eye. In people with retinitis pigmentosa, vision loss occurs as the light-sensing cells of the retina gradually deteriorate.
  • 1.1K
  • 04 Jan 2021
Topic Review
Chronic Kidney Disease (CKD)
Chronic kidney disease, also referred to as end-stage renal disease (ESRD), is a prevalent and chronic condition for which treatment is necessary as a means of survival once affected individuals reach the fifth and final stage of the disease. Dialysis is a form of maintenance treatment that aids with kidney functioning once a normal kidney is damaged. There are two main types of dialysis: hemodialysis (HD) and peritoneal dialysis (PD). Each form of treatment is discussed between the patient and nephrologist and is largely dependent upon the following factors: medical condition, ability to administer treatment, supports, geographical location, access to necessary equipment/supplies, personal wishes, etc. For Indigenous Peoples who reside on remote Canadian First Nation communities, relocation is often recommended due to geographical location and limited access to both health care professionals and necessary equipment/supplies (i.e., quality of water, access to electricity/plumbing, etc.). Consequently, the objective of this paper is to determine the psychosocial and somatic effects for Indigenous Peoples with ESRD if they have to relocate from remote First Nation communities to an urban centre. A review of the literature suggests that relocation to urban centres has negative implications that are worth noting: cultural isolation, alienation from family and friends, somatic issues, psychosocial issues, loss of independence and role adjustment. As a result of relocation, it is evident that the impact is profound in terms of an individuals’ mental, emotional, physical and spiritual well-being. Ensuring that adequate social support and education are available to patients and families would aid in alleviating stressors associated with managing chronic kidney disease.
  • 1.1K
  • 17 Apr 2021
Topic Review
Marine Macroalgae as Inhibitors of Fungal Phytopathogens
Fungal phytopathogens are a growing problem all over the world; their propagation causes significant crop losses, affecting the quality of fruits and vegetables, diminishing the availability of food, leading to the loss of billions of euros every year. To control fungal diseases, the use of synthetic chemical fungicides is widely applied; these substances are, however, environmentally damaging. Marine algae, one of the richest marine sources of compounds possessing a wide range of bioactivities, present an eco-friendly alternative in the search for diverse compounds with industrial applications.
  • 1.1K
  • 17 Dec 2021
Topic Review
Dental Implants and Thickness of Cortical Bone
Dental implantation exhibits a high and predictable prevalence of success, but correct assessment of the relation between bone quality, primary stability and osseointegration of implants is still a major challenge. For example, the relationship between a denser thickness of cortical bone and implant stability has been the subject of low-quality clinical reports only, and this has not helped clinicians wishing to use this type of bone to design, prepare or place dental implants. Nevertheless, knowledge of this topic is important to refine the practice of dental implantation, as well as to minimize the risks of its failure.
  • 1.1K
  • 20 Dec 2021
Topic Review
Specialized Pro-Resolving Mediators Biomarkers
The application of precision medicine paradigm in the daily treatment of patients has been greatly hampered by the lack of robust biomarkers. Lipid mediators are central in the regulation of host immune responses during both the initiation and resolution of inflammation. Amongst lipid mediators, the specialized pro-resolving mediators (SPM) govern immune cells to promote the resolution of inflammation. These autacoids are produced via the stereoselective conversion of essential fatty acids to yield molecules that are dynamically regulated during inflammation and exert potent immunoregulatory activities. Furthermore, there is an increasing appreciation for the role that these mediators play in conveying the biological actions of several anti-inflammatory therapeutics. Identification and quantitation of these mediators has traditionally been achieved using hyphenated mass spectrometric techniques, primarily liquid-chromatography tandem mass spectrometry. 
  • 1.1K
  • 03 Mar 2022
Topic Review
Cigarette Smoking and Human Gut Microbiota
The intestinal microbiota is a crucial regulator of human health and disease because of its interactions with the immune system. Tobacco smoke also influences the human ecosystem with implications for disease development. This entry aims to analyze the available evidence, until June 2021, on the relationship between traditional and/or electronic cigarette smoking and intestinal microbiota in healthy human adults.
  • 1.1K
  • 07 Mar 2022
Topic Review
HFpEF
Heart failure (HF) with preserved left ventricular ejection fraction (HFpEF) is becoming the predominant form of HF. However, medical therapy that improves cardiovascular outcome in HF patients with almost normal and normal systolic left ventricular function, but diastolic dysfunction is missing. The cause of this unmet need is incomplete understanding of HFpEF pathophysiology, the heterogeneity of the patient population, and poor matching of therapeutic mechanisms and primary pathophysiological processes.
  • 1.1K
  • 11 Mar 2022
Topic Review
Multi-Criteria Decision-Making Evaluation
China is a major maritime country with numerous islands, which are rich in natural resources. Island resources exhibit excellent development potential; in this regard, the market demand for uninhabited island development has been strong. The scientific and reasonable utilization of the resources of uninhabited islands can create huge economic value for the region and the country, inject vitality into the national economy, and enhance the stability of the overall sustainable development of the national economy. However, previous research on islands focused on a limited area of economy or ecology, and few studies provide a comprehensive evaluation of uninhabited island development. Such development requires enormous investment and has a profound impact. Therefore, a comprehensive and scientific evaluation system is necessary for uninhabited island development planning. This entry accordingly develops an island planning and evaluation indicator system based on multi-criteria decision-making (MCDM), and entropy analysis method, and the approach of Technique for Order Preference by Similarity to an Ideal Solution (TOPSIS).
  • 1.1K
  • 31 Mar 2022
Topic Review
A healthy socioemotional foundation in education
In the early school years, the emphasis is more and more on cognitive output factors. Non-cognitive development is receiving less attention than before, though such factors are important determinants of academic success. This study focuses on socioemotional characteristics, more specifically, on attitudes, behavior, and relationships of 6500 grade 2 pupils who participated in the representative Dutch large-scale cohort study COOL5-18. The results showed that the teachers rated their pupil’s work attitude as lower than their behavior and popularity. They were more positive regarding their relationship with the pupils. More important was that there were differences according to the pupils’ social and ethnic/immigrant backgrounds: ethnic minority/immigrant pupils scored less positive on all non-cognitive characteristics than native Dutch pupils, and the higher the parental educational level, the more favorable their children performed on the non-cognitive characteristics. These findings are discussed and possible solutions are presented.
  • 1.1K
  • 20 Apr 2022
  • Page
  • of
  • 2729
Featured Entry Collections
>>

Featured Reprints

>>
Encyclopedia of Digital Society, Industry 5.0 and Smart City
Encyclopedia of Engineering
Encyclopedia of Social Sciences
Encyclopedia of Medieval Royal Iconography
Academic Video Service
Feedback