Your browser does not fully support modern features. Please upgrade for a smoother experience.
Submitted Successfully!
Thank you for your contribution! You can also upload a video entry or images related to this topic. For video creation, please contact our Academic Video Service.
Version Summary Created by Modification Content Size Created at Operation
1 Rita Xu + 721 word(s) 721 2020-12-15 07:35:55

Video Upload Options

We provide professional Academic Video Service to translate complex research into visually appealing presentations. Would you like to try it?
No, upload directly Yes
Cite
If you have any further questions, please contact Encyclopedia Editorial Office.
Xu, R. Progressive Familial Heart Block. Encyclopedia. Available online: https://encyclopedia.pub/entry/5463 (accessed on 26 September 2026).
Xu R. Progressive Familial Heart Block. Encyclopedia. Available at: https://encyclopedia.pub/entry/5463. Accessed September 26, 2026.
Xu, Rita. "Progressive Familial Heart Block" Encyclopedia, https://encyclopedia.pub/entry/5463 (accessed September 26, 2026).
Xu, R. (2020, December 24). Progressive Familial Heart Block. In Encyclopedia. https://encyclopedia.pub/entry/5463
Xu, Rita. "Progressive Familial Heart Block." Encyclopedia. Web. 24 December, 2020.
Progressive Familial Heart Block
Edit
This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/condition/progressive-familial-heart-block

Progressive familial heart block is a genetic condition that alters the normal beating of the heart.

genetic conditions

References

  1. Barra SN, Providência R, Paiva L, Nascimento J, Marques AL. A review onadvanced atrioventricular block in young or middle-aged adults. Pacing ClinElectrophysiol. 2012 Nov;35(11):1395-405. doi: 10.1111/j.1540-8159.2012.03489.x.
  2. Fernandez P, Corfield VA, Brink PA. Progressive familial heart block type II(PFHBII): a clinical profile from 1977 to 2003. Cardiovasc J S Afr. 2004May-Jun;15(3):129-32.
  3. Fernandez P, Moolman-Smook J, Brink P, Corfield V. A gene locus forprogressive familial heart block type II (PFHBII) maps to chromosome1q32.2-q32.3. Hum Genet. 2005 Oct;118(1):133-7.
  4. Kruse M, Schulze-Bahr E, Corfield V, Beckmann A, Stallmeyer B, Kurtbay G,Ohmert I, Schulze-Bahr E, Brink P, Pongs O. Impaired endocytosis of the ionchannel TRPM4 is associated with human progressive familial heart block type I. JClin Invest. 2009 Sep;119(9):2737-44. doi: 10.1172/JCI38292.
  5. Lee CK, Shin DH, Jang JK, Jang KH, Kim EK, Cheong SS, Yoo SY. Progressivefamilial heart block type I in a korean patient. Korean Circ J. 2011May;41(5):276-9. doi: 10.4070/kcj.2011.41.5.276.
  6. Makita N, Seki A, Sumitomo N, Chkourko H, Fukuhara S, Watanabe H, Shimizu W,Bezzina CR, Hasdemir C, Mugishima H, Makiyama T, Baruteau A, Baron E, Horie M,Hagiwara N, Wilde AA, Probst V, Le Marec H, Roden DM, Mochizuki N, Schott JJ,Delmar M. A connexin40 mutation associated with a malignant variant ofprogressive familial heart block type I. Circ Arrhythm Electrophysiol. 2012Feb;5(1):163-72. doi: 10.1161/CIRCEP.111.967604.
  7. Probst V, Allouis M, Sacher F, Pattier S, Babuty D, Mabo P, Mansourati J,Victor J, Nguyen JM, Schott JJ, Boisseau P, Escande D, Le Marec H. Progressivecardiac conduction defect is the prevailing phenotype in carriers of a Brugadasyndrome SCN5A mutation. J Cardiovasc Electrophysiol. 2006 Mar;17(3):270-5.
  8. Schott JJ, Alshinawi C, Kyndt F, Probst V, Hoorntje TM, Hulsbeek M, Wilde AA, Escande D, Mannens MM, Le Marec H. Cardiac conduction defects associate withmutations in SCN5A. Nat Genet. 1999 Sep;23(1):20-1.
  9. Van der Merwe PL, Weymar HW, Torrington M, Brink AJ. Progressive familialheart block (type I). A follow-up study after 10 years. S Afr Med J. 1988 Mar5;73(5):275-6.
  10. Watanabe H, Koopmann TT, Le Scouarnec S, Yang T, Ingram CR, Schott JJ,Demolombe S, Probst V, Anselme F, Escande D, Wiesfeld AC, Pfeufer A, Kääb S,Wichmann HE, Hasdemir C, Aizawa Y, Wilde AA, Roden DM, Bezzina CR. Sodium channelβ1 subunit mutations associated with Brugada syndrome and cardiac conductiondisease in humans. J Clin Invest. 2008 Jun;118(6):2260-8. doi: 10.1172/JCI33891.
More
©Text is available under the terms and conditions of the Creative Commons-Attribution ShareAlike (CC BY-SA) license; additional terms may apply. By using this site, you agree to the Terms and Conditions and Privacy Policy.
Upload a video for this entry
Information
Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Rita Xu
View Times: 1.1K
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 24 Dec 2020
Table of Contents
    Notice
    You are not a member of the advisory board for this topic. If you want to update advisory board member profile, please contact office@encyclopedia.pub.
    OK
    Confirm
    Only members of the Encyclopedia advisory board for this topic are allowed to note entries. Would you like to become an advisory board member of the Encyclopedia?
    Yes
    No
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    There is no comment~
    ${ textCharacter }/${ maxCharacter }
    Submit
    Cancel
    ${ selectedItem.replyTextCharacter }/${ selectedItem.replyMaxCharacter }
    Submit
    Cancel
    Confirm
    Are you sure to Delete?
    Yes No
    Academic Video Service
    Feedback