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Topic Review
Oenological Fermentation
Wine fermentation is a specific and complex research subject and its control is essential to ensure full process completion while improving wine quality. It displays several specificities, in particular, (i) musts with a very high sugar content, low pH, and some limiting nutrients, as well as a great variability in must composition according to the year, grape variety, and so on; (ii) atypical fermentation conditions with non-isothermal temperature profiles, a quasi-anaerobiosis and legal constraints with a limited and predefined list of authorized operations. New challenges have emerged, related to the increasing diversity of commercially available yeast strains; the fluctuating composition of musts, particularly owing to climate change; and sustainability, which has become a key issue. 
  • 1.2K
  • 08 Sep 2021
Topic Review
Mechanism of Metal Homeostasis in Plants
Heavy metal stress (HMS) is one of the most destructive abiotic stresses which seriously affects the growth and development of plants. In general, three core signals are involved in plants’ responses to HMS; these are mitogen-activated protein kinase (MAPK), calcium, and hormonal (abscisic acid) signals. In addition to these signal components, other regulatory factors, such as microRNAs and membrane proteins, also play an important role in regulating HMS responses in plants. 
  • 1.2K
  • 24 Dec 2021
Topic Review
Antibiotics and Their Impact on Bacterial Cellular Perturbation
Antibiotics belong to different classes of chemicals—including those of biological, synthetic, or semi-synthetic origin—and have selective modes of action. Based on their mechanisms of action, antimicrobial compounds are classified into two groups: bacteriostatic and bactericidal. Resistance is a natural adaptive tool that offers selection pressure to bacteria, and hence cannot be stopped entirely but rather be slowed down. Antibiotic resistance mutations mostly diminish bacterial reproductive fitness in an environment without antibiotics; however, a fraction of resistant populations ‘accidentally’ emerge as the fittest and thrive in a specific environmental condition, thus favouring the origin of a successful resistant clone.
  • 1.2K
  • 11 Jan 2022
Topic Review
Pontifical Academy of Sciences
The Pontifical Academy of Sciences (Italian: Pontificia accademia delle scienze, Latin: Pontificia Academia Scientiarum) is a scientific academy of the Vatican City, established in 1936 by Pope Pius XI, and thriving with the blessing of the Papacy ever since. Its aim is to promote the progress of the mathematical, physical, and natural sciences and the study of related epistemological problems. The Academy has its origins in the Accademia Pontificia dei Nuovi Lincei ("Pontifical Academy of the New Lynxes"), founded in 1847 as a more closely supervised successor to the Accademia dei Lincei ("Academy of Lynxes") established in Rome in 1603 by the learned Roman Prince, Federico Cesi (1585–1630), who was a young botanist and naturalist, and which claimed Galileo Galilei as its president. The Accademia dei Lincei survives as a wholly separate institution. The Academy of Sciences, one of the Pontifical academies at the Vatican in Rome, is headquartered in the Casina Pio IV in the heart of the Vatican Gardens. The academy holds a membership roster of the most respected names in 20th century science, including such Nobel laureates as Ernest Rutherford, Max Planck, Otto Hahn, Niels Bohr, Erwin Schrödinger, and Charles Hard Townes.
  • 1.2K
  • 09 Oct 2022
Topic Review
Established Opto-Chemical Tools
As light inherently possesses exceptional spatiotemporal precision, photo-responsive molecules are great candidates for the modulation of biological activities with high spatiotemporal resolution. The two most common opto-chemical strategies are photo-induced conformational changes and light-induced uncaging which typically implies chemical caging of small molecules, oligonucleotides, and peptides and proteins.
  • 1.2K
  • 11 Oct 2022
Topic Review
X-ray Absorption Near Edge Structure
X-ray absorption near edge structure (XANES), also known as near edge X-ray absorption fine structure (NEXAFS), is a type of absorption spectroscopy that indicates the features in the X-ray absorption spectra (XAS) of condensed matter due to the photoabsorption cross section for electronic transitions from an atomic core level to final states in the energy region of 50–100 eV above the selected atomic core level ionization energy, where the wavelength of the photoelectron is larger than the interatomic distance between the absorbing atom and its first neighbour atoms.
  • 1.2K
  • 18 Oct 2022
Topic Review
Dynamic SSL
Dynamic SSL is an endpoint security technology developed by Daniel McCann and Nima Sharifimehr of NetSecure Technologies Ltd. Dynamic SSL was created to solve the endpoint security problem in public networks by transparently correcting the implementation flaws in SSL systems that expose sensitive data to interception and tampering. Dynamic SSL is sometimes referred to as Dynamic TLS.
  • 1.2K
  • 16 Nov 2022
Topic Review
Circulating Tumor Cells in Colorectal Cancer
Circulating tumor cells (CTCs)  are intact cells separated from the primary tumor or metastases and released into the peripheral circulation. They were observed and discovered for the first time in 1869 in the blood of a patient with breast cancer. CTCs mainly originate from solid tumors of epithelial origin (breast, prostate, colon, and lung). CTCs are nucleated and express epithelial cell adhesion molecules (EpCAM) and/or cytokeratins (CK) in the cytoplasm without coexpressing the common leukocyte antigen CD45. It is known today that there is significant heterogeneity in cell species and surface markers, which represents a challenge in isolating all clinically relevant subpopulations of CTCs.
  • 1.2K
  • 22 Nov 2022
Topic Review
Phenoxypyridine as an Active Scaffold for Pesticides
Phenoxypyridine, the bioisostere of diaryl ethers, has been widely introduced into bioactive molecules as an active scaffold, which has different properties from diaryl ethers. In this paper, the bioactivities, structure-activity relationships, and mechanism of compounds containing phenoxypyridine were summarized, which may help to explore the lead compounds and discover novel pesticides with potential bioactivities.
  • 1.2K
  • 12 Dec 2022
Topic Review
Bismuth Halide Perovskites for CO2 Photoreduction
Inspired by natural photosynthesis, the photocatalytic CO2 reduction reaction (CO2RR) stands as a viable strategy to produce solar fuels and mitigate the high dependence on highly polluting fossil fuels, as well as to decrease the CO2 concentration in the atmosphere. The design of efficient photocatalytic materials is crucial to ensure the long-term application of the CO2RR process. So far, perovskite materials have shown high efficiencies in CO2RR to generate different solar fuels, specially lead halide perovskites (LHP), which exhibit valuable features for the obtention of high production yields (e.g., narrow band gaps, adequate potentials for CO2RR, good charge transport properties, etc.). Nonetheless, the presence of lead involves an important environmental impact that cannot be negligible in the design of industrial-scale photocatalytic processes. Hence, the search for efficient Lead-free Halide Perovskites (LFHP) remains a high-priority task in the research of functional materials for CO2RR, since LFHPs could maintain the properties of LHPs, while keeping low environmental impacts and accessible costs of production. As an alternative, bismuth-based LFHPs have gained much attention due to their higher absorption coefficients, their more efficient charge transfer (compared to oxide perovskites), and their required thermodynamic potential for CO2RR. However, despite all the remarkable advantages of bismuth halide perovskites, their use has been limited, owing to instability concerns. The performance of bismuth-based LFHPs are discussed, as well as stability strategies from intrinsic and extrinsic standpoints.
  • 1.2K
  • 13 Dec 2022
Topic Review
Iron Metabolism and Ferroptosis in Male Reproductive System
Ferroptosis, an iron-dependent type of regulated cell death, is triggered by the accumulation of lethal lipid peroxides. The cellular iron metabolism is essential for maintaining life activities in normal biological processes, including the generation of cellular energy, oxygen transport, heme synthesis, DNA synthesis and repair, etc. Notably, studies show that the iron metabolism is also quite important for the reproductive system and is intimately related to spermatogenesis. The relationship between the abnormal iron metabolism and ferroptosis in male reproductive disorders is gaining increasing attention.
  • 1.2K
  • 09 Jan 2023
Topic Review
Euphorbia officinarum L.
Euphorbia officinarum L. is a Moroccan endemic plant known as “Tikiout” and “Daghmus” that can also be found in Mauritania, Western Sahara, and Algeria. This species has been used in folk medicine as anti-diabetic; in the treatment of skin diseases when associated with Opuntia ficus-barbarica, Zea mays and Ziziphus lotus, and honey for eliminating helminths, in the treatment of pyelonephritis and cystitis. Triterpenes, phytosterols and ingol diterpenes have been isolated and identified in the latex of Moroccan E. officinarum, nevertheless the biggest interest has been to obtain derivatives by hemisynthesis from natural triterpenes with insecticidal and antimicrobial activity. In Morocco, the E. officinarum honey is considered the most precious; nevertheless, many times it is mixed with other Euphorbiaceae honeys. To increase the commercial value of a monofloral E. officinarum honey, it would be important to find one or more specific markers for this type of honey to be sure of its authenticity.
  • 1.2K
  • 31 Jan 2023
Topic Review
Infrared and Visible Image Fusion Technologies
Infrared and visible image fusion is to combine the information of thermal radiation and detailed texture from the two images into one informative fused image. Deep learning methods have been widely applied in this task; however, those methods usually fuse multiple extracted features with the same fusion strategy, which ignores the differences in the representation of these features, resulting in the loss of information in the fusion process. Infrared and visible image fusion techniques can be divided into two categories: traditional methods and deep learning-based methods. Traditional methods have been proposed for the fusion of pixel-level or fixed features. 
  • 1.2K
  • 03 Feb 2023
Topic Review
TLS Survey for Heritage Building Information Modeling
Heritage Building Information Modeling (HBIM) is an essential technology for heritage documentation, conservation, and management. It enables people to understand, archive, advertise, and virtually reconstruct their built heritage. Creating highly accurate HBIM models requires the use of several reality capture tools, such as terrestrial laser scanning (TLS), photogrammetry, unmanned aerial vehicles (UAV), etc. 
  • 1.2K
  • 25 Apr 2023
Topic Review
MOS Gas Sensor for Lung Cancer Diagnosis
Lung cancer is the most prevalent severe illness in both sexes and all ages and the leading cause of cancer-related deaths globally. Late-stage diagnosis is the primary cause of its high mortality rate. Therefore, the management of lung cancer needs early-stage screening. Breath analysis is a non-invasive, low-cost, and user-friendly approach to diagnosing lung cancer. Among the various types of breath sensors, metal oxide semiconductor (MOS) gas sensors are preferred due to their high gas responses, fast response times, robustness, and lower price.
  • 1.2K
  • 06 May 2023
Topic Review
Cross-Platform User-Generated Content
User-generated content (UGC) from e-commerce platforms and third-party platforms can impact customer-perceived risk and influence product sales in online stores. However, the understanding of UGC from which platform type yields a stronger effect on product sales and how the effects interact across the platforms remains limited, especially from a cross-platform UGC perspective. 
  • 1.2K
  • 14 Aug 2023
Topic Review
Green Balanced Scorecard
A green balanced scorecard allows businesses to monitor their environmental progress and energy use, as well as quantify their achievements toward decreasing their ecological footprint. Businesses have made it a priority to build an energy-efficient management system based on the Sustainable Balanced Scorecard, which will help them achieve their organization’s environmental strategic goals. 
  • 1.2K
  • 25 Sep 2023
Topic Review
Diet, Nutrition, and Oral Health in Older Adults
Diet, nutrition, and oral health are closely linked. Malnutrition is a challenging health concern in older adults that is associated with physical decline affecting their daily activities and quality of life.
  • 1.2K
  • 07 Oct 2023
Topic Review
Additively Manufactured Polymeric Metamaterials
Metamaterials are architected cellular materials, also known as lattice materials, that are inspired by nature or human engineering intuition and provide multifunctional attributes that cannot be achieved by conventional polymeric materials and composites. There has been an increasing interest in the design, fabrication, and testing of polymeric metamaterials due to the recent advances in digital design methods, additive manufacturing techniques, and machine learning algorithms. 
  • 1.2K
  • 24 Nov 2023
Topic Review
The Language of Deception
Digital forensic investigations are becoming increasingly crucial in criminal investigations and civil litigations, especially in cases of corporate espionage and intellectual property theft as more communication occurs online via e-mail and social media. Deceptive opinion spam analysis is an emerging field of research that aims to detect and identify fraudulent reviews, comments, and other forms of deceptive online content. 
  • 1.2K
  • 09 Jan 2024
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