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Topic Review
Hyperchloremia
Hyperchloremia is an electrolyte disturbance in which there is an elevated level of chloride ions in the blood. The normal serum range for chloride is 96 to 106 mEq/L, therefore chloride levels at or above 110 mEq/L usually indicate kidney dysfunction as it is a regulator of chloride concentration. As of now there are no specific symptoms of hyperchloremia; however, it can be influenced by multiple abnormalities that cause a loss of electrolyte-free fluid, loss of hypotonic fluid, or increased administration of sodium chloride. These abnormalities are caused by diarrhea, vomiting, increased sodium chloride intake, renal dysfunction, diuretic use, and diabetes. Hyperchloremia should not be mistaken for hyperchloremic metabolic acidosis as hyperchloremic metabolic acidosis is characterized by two major changes: a decrease in blood pH and bicarbonate levels, as well as an increase in blood chloride levels. Instead those with hyperchloremic metabolic acidosis are usually predisposed to hyperchloremia. Hyperchloremia prevalence in hospital settings has been researched in the medical field since one of the major sources of treatment at hospitals is administering saline solution. Previously, animal models with elevated chloride have displayed more inflammation markers, changes in blood pressure, increased renal vasoconstriction, and less renal blood flow as well at glomerulus filtration, all of which are prompting researchers to investigate if these changes or others may exist in patients. Some studies have reported a possible relationship between increased chloride levels and death or acute kidney injury in severely ill patients that may frequent the hospital or have prolonged visits. There are other studies that have found no relationship. As studies continue, it is important to include a large patient sample size, a diverse patient population, and a diverse range of hospitals involved in these studies.
  • 1.6K
  • 11 Oct 2022
Topic Review
Alloplastic Bone Substitutes
Various bone graft products are commercially available worldwide. However, there is no clear consensus regarding the appropriate bone graft products in different clinical situations. This study is intended to summarize bone graft products, especially alloplastic bone substitutes that are available in multiple countries. It also provides dental clinicians with detailed and accurate information concerning these products. Furthermore, it discusses the prospects of alloplastic bone substitutes based on an analysis of the current market status, as well as a comparison of trends among countries. 
  • 1.6K
  • 17 Mar 2021
Topic Review
Dissociation
Dissociation in chemistry and biochemistry is a general process in which molecules (or ionic compounds such as salts, or complexes) separate or split into other things such as atoms, ions, or radicals, usually in a reversible manner. For instance, when an acid dissolves in water, a covalent bond between an electronegative atom and a hydrogen atom is broken by heterolytic fission, which gives a proton (H+) and a negative ion. Dissociation is the opposite of association or recombination.
  • 1.6K
  • 24 Oct 2022
Topic Review
Vinyl Ether
Vinyl ether is the organic compound with the formula O(CH=CH2)2. Other names include divinyl ether, divinyl oxide, ethenoxyethene. It is a colorless, volatile liquid. Under the tradename vinethene, vinyl ether was once used as an inhalation anesthetic. The analytical techniques used to study its pharmacology laid the groundwork for the testing of new anesthetic agents. Many divinyl ether derivatives of fatty acids exist in nature.
  • 1.6K
  • 28 Oct 2022
Topic Review
Coconut-Based Beverages and Value-Added Products
The definition of value addition is based on the process or processes which are used to transform, physically, the initial raw material into the final food or non-food article. Diversification can enhance the possibility of increased gains. Processing degree is a consequence of consumers’ requests. Three different drivers for value addition have been considered: packaging, durability, and size options; sensorial features; and sustainability. There are different value-added coconut-based beverages with interesting perspectives.
  • 1.6K
  • 02 Feb 2024
Topic Review
Fucoidan in Pharmaceutical Formulations
Fucoidan is a heterogeneous group of polysaccharides isolated from marine organisms, including brown algae and marine invertebrates. The physicochemical characteristics and potential bioactivities of fucoidan have attracted substantial interest in pharmaceutical industries. These polysaccharides are characterized by possessing sulfate ester groups that impart negatively charged surfaces, low/high molecular weight, and water solubility. In addition, various promising bioactivities have been reported, such as antitumor, immunomodulatory, and antiviral effects. Hence, the formulation of fucoidan has been investigated in diverse pharmaceutical dosage forms to be able to reach their site of action effectively. Moreover, they can act as carriers for various drugs in value-added drug delivery systems.
  • 1.6K
  • 20 Apr 2023
Topic Review
Wood Antimicrobial Behavior Test Method
Some wood species have antimicrobial properties and a variety of methods are used to investigate them. For testing the effect of antimicrobial compounds, direct and indirect methods are used. Meanwhile, the survival of microbes is also tested on surfaces (or material in contact with microbes) to validate the safety of surfaces.
  • 1.5K
  • 29 Oct 2020
Topic Review
ALK Inhibitor
ALK inhibitors are anti-cancer drugs that act on tumours with variations of anaplastic lymphoma kinase (ALK) such as an EML4-ALK translocation. They fall under the category of tyrosine kinase inhibitors, which work by inhibiting proteins involved in the abnormal growth of tumour cells. All the current approved ALK inhibitors function by binding to the ATP pocket of the abnormal ALK protein, blocking its access to energy and deactivating it. A majority of ALK-rearranged NSCLC harbour the EML4-ALK fusion, although as of 2020, over 92 fusion partners have been discovered in ALK+ NSCLC. For each fusion partner, there can be several fusion variants depending on the position the two genes were fused at, and this may have implications on the response of the tumour and prognosis of the patient.
  • 1.5K
  • 31 Oct 2022
Topic Review
1D MPC and Thin-Film Analysis
The development of magnetic photonic crystals (MPC) has been a rapidly evolving research area since the late 1990s. Magneto-optic (MO) materials and the techniques for their characterization have also continually undergone functional and property-related improvements. MPC Optimization is a feature-rich Windows software application designed to enable researchers to analyse the optical and magneto-optical spectral properties of multilayers containing gyrotropic constituents. A set of computational approaches, and a custom software package have been described, designed to enable the design and optimization of 1D magnetic photonic crystals in terms of the achievable combinations of Faraday rotation, transmission, and reflection spectra. 
  • 1.5K
  • 25 Aug 2021
Topic Review
BODIPY-Based Molecules for Organic PhotoVoltaics
The 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY)-based molecules have emerged as interesting material for optoelectronic applications. This type of structure is commonly described as an example of a “rigidified” monomethine cyanine dye or as a boradiazaindacene by analogy with the all-carbon tricyclic ring and the numbering of any substituents follows rule setup for the carbon polycycles (see COVER). This dye has also been  called “porphyrin’s little sister” and this happy definition has been so successful that in analogy with porphyrinic systems, the 8-position is often referred to as the meso site. The facile structural modification of BODIPY core provides an opportunity to fine-tune its photophysical and optoelectronic properties thanks to the presence of eight reactive sites which allows for the developing of a large number of functionalized derivatives for various applications. In particular, BODIPY dyes find increasing application in laser dyes, organic electronic (OLED and OPV), bioimmagining,  thanks to their properties  like high fluorescent quantum yield, sharp absorption and emission peak,  photostability and stability under physiological conditions. Because of this they can be used also  as probes for pH changes, detection of cations, anions and so on.
  • 1.5K
  • 01 Feb 2021
Topic Review
Tire-Derived Rubber Recycle
Rubber, as elastomer, is difficult to recycle. Today, the main end of life routes of tyres and other rubber products are landfilling, incineration in e.g. cement plants, and grinding to a fine powder, with huge quantities lacking sustainable recycling of this valuable material. Devulcanization, i.e. the breaking up of sulfur bonds by chemical, thermo-physical or biological means, is a promising route that has been investigated for more than 50 years. This review article presents and update on the state-of-the art in rubber devulcanization. This review article addresses established devulcanization technologies and novel processes described in the scientific and patent literatures. It is expected that the public discussion of environmental impacts of thermoplastics will soon spill over to thermosets and elastomers. Therefore, the industry needs to develop and market solutions proactively. Tyre recycling through devulcanization has a huge lever, since approx. 40 million tons of tyres are discarded annually.
  • 1.5K
  • 27 Oct 2020
Topic Review
Biological Carbon Fixation
Biological carbon fixation or сarbon assimilation is the process by which inorganic carbon (particularly in the form of carbon dioxide) is converted to organic compounds by living organisms. The compounds are then used to store energy and as structure for other biomolecules. Carbon is primarily fixed through photosynthesis, but some organisms use a process called chemosynthesis in the absence of sunlight. Organisms that grow by fixing carbon are called autotrophs, which include photoautotrophs (which use sunlight), and lithoautotrophs (which use inorganic oxidation). Heterotrophs are not themselves capable of carbon fixation but are able to grow by consuming the carbon fixed by autotrophs or other heterotrophs. "Fixed carbon", "reduced carbon", and "organic carbon" may all be used interchangeably to refer to various organic compounds. Chemosynthesis is carbon fixation driven by chemical energy, rather than from sunlight. Sulfur- and hydrogen-oxidizing bacteria often use the Calvin cycle or the reductive citric acid cycle.
  • 1.5K
  • 02 Dec 2022
Topic Review
Expanding Monomers
Expanding Monomers are monomers which are increasing in volume (expanding) during polymerization. They can be added to monomer formulations to counteract the usual volume shrinking (during polymerization) to manufacture products with higher quality and durability. Volume Shrinkage is in first line for the unmeltable thermosets a problem, since those are of fixed shape after polymerization completed.:2
  • 1.5K
  • 25 Oct 2022
Topic Review
3D Graphene-Based Toxic Gas Sensors
Air pollution is becoming an increasingly important global issue. Toxic gases such as ammonia, nitrogen dioxide, and volatile organic compounds (VOCs) like phenol are very common air pollutants. To date, various sensing methods have been proposed to detect these toxic gases. Researchers are trying their best to build sensors with the lowest detection limit, the highest sensitivity, and the best selectivity. As a 2D material, graphene is very sensitive to many gases and so can be used for gas sensors. Recent studies have shown that graphene with a 3D structure can increase the gas sensitivity of the sensors. The limit of detection (LOD) of the sensors can be upgraded from ppm level to several ppb level.
  • 1.5K
  • 25 Aug 2021
Topic Review
Biochar-Based Adsorption Processes: Considerations for Antibiotics Removal
Antibiotics are pharmaceuticals that are used to treat bacterial infections in humans and animals, and they are also used as growth promoters in livestock production. These activities lead to an alarming accumulation of antibiotics in aquatic environments, resulting in selection pressure for antibiotic resistance. Carbon-based materials (mainly in the form of activated carbons, carbon nanotubes, graphene, and biochars) are commonly used for the adsorption of antibiotics because of their four characteristics that contribute to adsorption, including specific surface area, micro- and mesopore structures, surface functional groups;mineral content and composition.
  • 1.5K
  • 17 Nov 2023
Topic Review
Electroplated Functional Materials
Electroplating has been favored to date as a surface treatment technology in various industries in the development of semiconductors, automobiles, ships, and steel due to its advantages of being a simple, solution-based process, with low cost and high throughput. Recently, classical electroplating has been reborn as an advanced manufacturing process for functional materials by combining it with unconventional optical three-dimensional (3D) nanofabrication techniques capable of generating polymer templates with high-resolution 3D periodic nanostructures.
  • 1.5K
  • 29 Dec 2020
Topic Review
Recovery Copper Using CSP
On the one hand, copper slag is nowadays a waste in copper pyrometallurgy despite the significant quantities of iron (>40 wt. %) and copper (1 to 2 wt. %). On the other hand, solar energy, when properly concentrated, offers great potential in high-temperature processes. Therefore, concentrated solar power (CSP) could be used in the treatment of copper slag to transform fayalite into magnetite and copper sulfides and oxides into copper nodules. This is the objective of this paper. The results show that fayalite was partially decomposed into magnetite and silica. Moreover, copper nodules (65–85 wt. % Cu) were identified in the treated samples, while the initial slag, analyzed by X-ray diffraction, X-ray fluorescence, and SEM-EDX, did not show the presence of metallic copper. Finally, the treated copper slag was crushed and grinded down to 40 μm, and two fractions were obtained by magnetic separation. The magnetic fraction (85%) was mainly comprised of magnetite, while the non-magnetic fraction (15%) had 5–10 wt. % Cu. Considering the experimental results, 7.5–18 kg Cu/t slag might be recovered from the slag. A preliminary economic analysis, considering the current copper price, indicates that only the recovery of copper could represent a significant economic benefit (>30 €/t slag). Therefore, CSP might be a potential candidate for the treatment of copper slag to recover copper and iron.
  • 1.5K
  • 23 Jul 2021
Topic Review
Advanced Mass Spectrometry in Service of Forensic Analysis
Mass spectrometry has been used to assist forensic investigation. Due to its unique capabilities, mainly high-resolution mass data and structural information, high sensitivity, and cooperation with separation techniques, this method provides access to many tools streamlining and accelerating sample analysis. Low analyte consumption, advanced derivatization procedures and availability of isotopically labeled standards offer opportunities to study materials previously not considered viable evidence, opening new avenues in forensic investigations.
  • 1.5K
  • 25 Aug 2022
Topic Review
Shape Changing Materials
This short review is the applications section of our original paper that reviews materials and structures displaying non-conventional deformations as a response to different actuations (e.g., electricity, heat and mechanical loading).
  • 1.5K
  • 27 Oct 2020
Topic Review
Silver Nanoparticles
The silver nanoparticles (AgNPs) have been shown to have bactericidal action. In this study, we demonstrated that ultraviolet A (UVA) irradiation of AgNPs is effective at enhancing their activity. This bactericidal effect is attributable to the UV irradiation-mediated enhanced production of highly reactive hydroxyl radicals generated from AgNPs. The method of UV irradiation is very simple. The UV radiation used in this study was UVA, which is safer for humans than UVC as known to have a strong bactericidal activity. Although challenges persist regarding the effects of AgNPs on human health and the elucidation of the molecular mechanisms underlying the generation of radicals, our findings would contribute to the development of medical materials for further protection against infection.
  • 1.5K
  • 28 Jul 2020
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