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Topic Review
Teleparallel Equivalent of General Relativity
The teleparallel equivalent of general relativity (TEGR) is an alternative geometrical formulation of the relativistic theory of gravitation. A brief description of the  TEGR is presented. The building blocks of the theory and few main achievements are discussed.
  • 5.1K
  • 30 Oct 2020
Topic Review
The State of Drinking Water in Kazakhstan
Kazakhstan has rich drinking water resources, but its uneven distribution and quality is an acute problem that needs to be solved. This article presents the current state of drinking water in the country, especially in its northern region - Akmola region, as based on statistical data, it has the worst indicators of drinking water and the reasons for such values are clarified. The only solution to this situation is a complete modernization of the water supply system through strict control of design and estimate documentation and proper planning of construction.
  • 5.1K
  • 02 Sep 2025
Topic Review
Christianity and Theosophy
Christianity and Theosophy, for more than a hundred years, have had a "complex and sometimes troubled" relationship. The Christian faith was the native religion of the great majority of Western Theosophists, but many came to Theosophy through a process of opposition to Christianity. According to professor Robert S. Ellwood, "the whole matter has been a divisive issue within Theosophy."
  • 5.1K
  • 17 Nov 2022
Topic Review
Primitive Clay Oven
The primitive clay oven, or earthen oven / cob oven, has been used since time immemorial by diverse cultures and societies, primarily for, but not exclusive to, baking before the invention of cast-iron stoves, and gas and electric ovens. The general build and shape were, mostly, common to all peoples, with only slight variations in size and in materials used to construct the oven. In primitive courtyards and farmhouses, earthen ovens were built on the ground. In Arabian, Palestinian, Middle-Eastern and North-African societies, bread was often baked within a clay oven called in some Arabic dialects a tabun (also transliterated taboon, from the Arabic: طابون), or else in a clay oven called a tannour, and in other dialects mas'ad. The clay oven, synonymous with the Hebrew word tannour (= oven), was shaped like a truncated cone, with an opening either at the top or bottom from which to stoke the fire. Others were made cylindrical with an opening at the top. Built and used in biblical times as the family, neighbourhood, or village oven, clay ovens continue to be made in parts of the Middle East today.
  • 5.1K
  • 22 Nov 2022
Topic Review
Dipole Moment
Synthesis, biological activity and structure-activity relationships of diverse compounds are described. The relationships between dipole moment and biological activities are discussed. Despite the progress of interdisciplinary science, the use of dipole moment values of organic compounds to understand their potent medicinal activities in various diseases remains unexplored.
  • 5.1K
  • 25 Nov 2020
Topic Review
Binders Used for the Manufacturing of Composite Materials
Binders, or tackifiers, have become widespread in the production of new composite materials by liquid composite molding (LCM) techniques due to their ability to stabilize preforms during laying-up and impregnation, as well as to improve fracture toughness of the obtained composites, which is very important in aviation, automotive, ship manufacturing, etc. Furthermore, they can be used in modern methods of automatic laying of dry fibers into preforms, which significantly reduces the labor cost of the manufacturing process.
  • 5.1K
  • 19 Jan 2022
Topic Review
E-Fuels
Power-to-X (PtX) are fuel production pathways in which electricity is converted into various gaseous or liquid fuels, such as e-hydrogen, e-methanol, e-methane, dimethyl ether (E-DME), e-ammonia, or e-diesel. These fuels are also named electrofuels (e-fuel) or power-to-liquid (PtL) and are mentioned in the Annexes of the RED II amendments as alternative options for the decarbonisation of the transport sector. Some of these molecules still contain carbon atoms, thus producing CO2 when used for energy production. The carbon source for the synthesis of e-fuels has to be carefully analysed to define them really carbon neutral.
  • 5.1K
  • 27 Feb 2023
Topic Review
Deformation
In physics, deformation is the continuum mechanics transformation of a body from a reference configuration to a current configuration. A configuration is a set containing the positions of all particles of the body. A deformation can occur because of external loads, intrinsic activity (e.g. muscle contraction), body forces (such as gravity or electromagnetic forces), or changes in temperature, moisture content, or chemical reactions, etc. Strain is related to deformation in terms of relative displacement of particles in the body that excludes rigid-body motions. Different equivalent choices may be made for the expression of a strain field depending on whether it is defined with respect to the initial or the final configuration of the body and on whether the metric tensor or its dual is considered. In a continuous body, a deformation field results from a stress field due to applied forces or because of some changes in the temperature field of the body. The relation between stress and strain is expressed by constitutive equations, e.g., Hooke's law for linear elastic materials. Deformations which cease to exist after the stress field is removed are termed as elastic deformation. In this case, the continuum completely recovers its original configuration. On the other hand, irreversible deformations remain. They exist even after stresses have been removed. One type of irreversible deformation is plastic deformation, which occurs in material bodies after stresses have attained a certain threshold value known as the elastic limit or yield stress, and are the result of slip, or dislocation mechanisms at the atomic level. Another type of irreversible deformation is viscous deformation, which is the irreversible part of viscoelastic deformation. In the case of elastic deformations, the response function linking strain to the deforming stress is the compliance tensor of the material.
  • 5.1K
  • 09 Oct 2022
Topic Review
Apple Bioactive Compounds
Population studies have associated a diet high in fruits to lower incidence of cancer. Specifically, research shows that secondary plant metabolites known as phytochemicals, which are commonly found in fruits, have onco-preventive and chemo-protective effects. Apple is a commonly consumed fruit worldwide that is available all year round and is a rich source of phytochemicals. The health benefits of apples are thought to be mainly due to their phytochemical composition. Additionally, apple consumption is associated with lower incidence of some cancers based on animal and cell culture studies.
  • 5.1K
  • 30 Nov 2021
Topic Review
Power Architecture
Power Architecture is a registered trademark for similar reduced instruction set computing (RISC) instruction sets for microprocessors developed and manufactured by such companies as IBM, Freescale/NXP, AppliedMicro, LSI, Teledyne e2v and Synopsys. The governing body is Power.org, comprising over 40 companies and organizations. "Power Architecture" is a broad term including all products based on newer POWER, PowerPC and Cell processors. The term "Power Architecture" should not be confused with IBM's different generations of "POWER Instruction Set Architecture", an earlier instruction set for IBM RISC processors of the 1990s from which the PowerPC instruction set was derived. Power Architecture is a family name describing processor architecture, software, toolchain, community and end-user appliances and not a strict term describing specific products or technologies. More details and documentation on the Power Architecture can be found on the IBM Portal for OpenPOWER.
  • 5.1K
  • 18 Nov 2022
Topic Review
Traditional Healing Practices in Fiji
Traditional Healing Practices in Fiji means the therapies using ceremonies; plant-, animal-, or mineral-based medicines; energy therapies (also called biofield therapies). They are based on the belief that there are energy fields that flow through and around your body. When energy is flowing freely through your body, you have good emotional, physical and spiritual health. When you are ill, the energy flow is blocked 
  • 5.1K
  • 28 Sep 2021
Topic Review
Oxadiazole
Nowadays, an increasing number of heterocyclic-based drugs found application in medicinal chemistry and, in particular, as anticancer agents. In this context, oxadiazoles—five-membered aromatic rings—emerged for their interesting biological properties
  • 5.1K
  • 29 Apr 2021
Topic Review
Identity
Identity refers to the distinct and unique set of characteristics, qualities, beliefs, and affiliations that define an individual or a group. It encompasses various aspects, including personal attributes, cultural heritage, social roles, and a sense of belonging. Identity is dynamic, shaped by personal experiences, societal influences, and the interactions between individuals and their broader cultural, social, and historical contexts. It plays a crucial role in shaping how individuals perceive themselves and how they are perceived by others. Additionally, identity can be expressed through factors such as ethnicity, nationality, gender, religion, and personal values, contributing to the richness and diversity of human experiences.
  • 5.1K
  • 25 Jan 2024
Topic Review
Heteroaromatic Diazirines in Material and Medicinal Chemistry
In materials (polymer) science and medicinal chemistry, heteroaromatic derivatives play the role of the central skeleton in development of novel devices and discovery of new drugs. On the other hand, (3-trifluoromethyl)phenyldiazirine (TPD) is a crucial chemical method for understanding biological processes such as ligand–receptor, nucleic acid–protein, lipid–protein, and protein–protein interactions. In particular, use of TPD has increased in materials science to create novel electric and polymer devices with comparative ease and reduced costs. Therefore, a combination of heteroaromatics and (3-trifluoromethyl)diazirine is a promising option for creating better materials and elucidating the unknown mechanisms of action of bioactive heteroaromatic compounds.
  • 5.1K
  • 15 Feb 2023
Topic Review
Targeted Therapy for NSCLC Patients with EGFR Mutations
Oncogenic mutations within the epidermal growth factor receptor (EGFR) kinase domain are well-established driver mutations in non–small cell lung cancer (NSCLC). Small-molecule tyrosine kinase inhibitors (TKIs) specifically targeting these mutations have improved treatment outcomes for patients with this subtype of NSCLC. Multiple targeted agents, including first-, second- and third-generation EGFR TKIs, have been approved or are under active investigation for patients with EGFR-mutant NSCLC. The first-generation TKIs, including erlotinib and gefitinib, are reversible inhibitors, binding both to mutant as well as wild-type (WT) EGFR. The second-generation TKIs, including afatinib and dacomitinib, are irreversible inhibitors that covalently bind to EGFR. The third-generation EGFR TKIs, including osimertinib (AZD9291), aumolertinib (HS-10296) and alflutinib (AST2818), are irreversible inhibitors that selectively bind to mutant EGFR and show greater efficacy than the first- and second-generation TKIs. Osimertinib has been approved by the FDA for both frontline and second-line treatment of NSCLC with EGFR-sensitizing mutations. Aumolertinib (HS-10296) and alflutinib (AST2818) have been approved for the treatment of EGFR-mutant NSCLC in China. Acquired resistance inevitably occurs, and a promising new generation of EGFR-targeting agents is under investigation.
  • 5.1K
  • 09 Feb 2023
Topic Review
Adaptive Clustering
The paper is devoted to an overview of multi-agent principles, methods, and technologies intended to adaptive real-time data clustering. The proposed methods provide new principles of self-organization of records and clusters, represented by software agents, making it possible to increase the adaptability of different clustering processes significantly. The paper also presents a comparative review of the methods and results recently developed in this area and their industrial applications. An ability of self-organization of items and clusters suggests a new perspective to form groups in a bottom-up online fashion together with continuous adaption previously obtained decisions. Multi-agent technology allows implementing this methodology in a parallel and asynchronous multi-thread manner, providing highly flexible, scalable, and reliable solutions. Industrial applications of the intended for solving too complex engineering problems are discussed together with several practical examples of data clustering in manufacturing applications, such as the pre-analysis of customer datasets in the sales process, pattern discovery, and ongoing forecasting and consolidation of orders and resources in logistics, clustering semantic networks in insurance document processing. Future research is outlined in the areas such as capturing the semantics of problem domains and guided self-organization on the virtual market.
  • 5.1K
  • 08 Feb 2021
Topic Review
Skid Resistance in Road Transport
Skid resistance is a significant feature that provides consistent traffic safety management for road pavements. An appropriate level of Skid resistance describes the contribution that the pavement surface makes to tire/road friction, and the surface of the road pavement can reduce vehicle operation cost, traffic accidents, and fatalities, particularly in wet conditions. Wet conditions decrease the level of the skid resistance (pavement friction), and this may lead to serious struggles related to driving on the road pavement (e.g., skidding or hydroplaning), which contributes to higher crash rates. The knowledge of skid resistance is essential to ensure reliable traffic management in transportation systems. Thus, a suitable methodology of skid resistance measurement and the understanding of the characterization of the road pavement are key to allow safe driving conditions.
  • 5.1K
  • 23 Sep 2021
Topic Review
Physical Unclonable Function
A Physical Unclonable Function (PUF) is hardware that acts as a one-way function, whose each different instance provides unique outputs for the same distinct input. Although recent research has demonstrated the merits of PUFs as security primitives for resource-constrained computer systems, better implementations of them need to be identified by future research, in order for them to be commercially adopted. Nevertheless, PUFs have already found application in the implementation of a large number of cryptographic protocols and other security solutions. A number of well-known metrics have been proposed in the literature in order to assess the quality of individual PUF implementations as security mechanisms, in terms of the stability, uniqueness and randomness of their responses.
  • 5.1K
  • 24 Mar 2023
Topic Review
Fluid Catalytic Cracking
The fluid catalytic cracking (FCC) process is an alternative olefin production technology, with lower CO2 emission and higher energy-saving.
  • 5.1K
  • 23 Feb 2021
Topic Review
TCV and TGV Technology
Through ceramic via (TCV) technology expands the volume of high-precision and high-power thin-film circuits with 3D planar distribution, significantly improves the structural density and reduces the device size through via interconnection and circuit redistribution. Through glass via (TGV) technology has the advantages of high-density interconnection and low-loss transmission, which forms a highly reliable interconnection between the chip and the substrate, has higher I/O density and smaller spacing, and realizes passive on-chip devices, high-density copper interconnection and the heterogeneous integration of chips. Therefore, 3D integration and system-level packaging technology have developed rapidly.
  • 5.1K
  • 26 Jul 2023
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