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Topic Review
Spring Wheat Genetic Resources in Siberia
Spring wheat is an important crop in Russia, with an annual cropping area of 11–12 Mha. The main spring wheat-production belt stretches from the mid-Volga region across the southern Ural mountains to Western Siberia. This is a short-season crop grown from May to August in an extensive, rainfed cropping system dominated by cereals, and occasionally rotated with oilseed and legume crops. 
  • 1.3K
  • 25 Feb 2022
Topic Review
Dietary Supplements in Chemotherapy-Induced Peripheral Neuropathy
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the main and most prevalent side effects of chemotherapy, significantly affecting the quality of life of patients and the course of chemotherapeutic treatment. Acetyl-L-carnitine, vitamins (group B and E), extracts of medical plants, including goshajinkigan, curcumin and others, unsaturated fatty acids, as well as the diet composed of so-called “sirtuin-activating foods”, could change the typical way of treatment of CIPN, improve the quality of life of patients and maintain the continuity of chemotherapy. 
  • 1.3K
  • 24 Mar 2022
Topic Review
Electronic Data Interchange
Electronic data interchange (EDI) is the concept of businesses electronically communicating information that was traditionally communicated on paper, such as purchase orders and invoices. Technical standards for EDI exist to facilitate parties transacting such instruments without having to make special arrangements. EDI has existed at least since the early 70s, and there are many EDI standards (including X12, EDIFACT, ODETTE, etc.), some of which address the needs of specific industries or regions. It also refers specifically to a family of standards. In 1996, the National Institute of Standards and Technology defined electronic data interchange as "the computer-to-computer interchange of strictly formatted messages that represent documents other than monetary instruments. EDI implies a sequence of messages between two parties, either of whom may serve as originator or recipient. The formatted data representing the documents may be transmitted from originator to recipient via telecommunications or physically transported on electronic storage media." It distinguished mere electronic communication or data exchange, specifying that "in EDI, the usual processing of received messages is by computer only. Human intervention in the processing of a received message is typically intended only for error conditions, for quality review, and for special situations. For example, the transmission of binary or textual data is not EDI as defined here unless the data are treated as one or more data elements of an EDI message and are not normally intended for human interpretation as part of on-line data processing." In short, EDI can be defined as the transfer of structured data, by agreed message standards, from one computer system to another without human intervention.
  • 1.3K
  • 28 Sep 2022
Topic Review
Deep Sleep Therapy
Deep sleep therapy (DST), also called prolonged sleep treatment or continuous narcosis, is a discredited form of ostensibly psychiatric treatment in which drugs are used to keep patients unconscious for a period of days or weeks. The controversial practice led to the death of 25 patients in Chelmsford Private Hospital in New South Wales from the early 1960s to late 1970s.
  • 1.3K
  • 09 Nov 2022
Topic Review
Udall Family
The Udall family is a U.S. political family rooted in the American West. Its role in politics spans over 100 years and four generations. Udall politicians have been elected from four different states: Arizona, Colorado, New Mexico, and Oregon. If viewed as a combined entity, the Udall-Hunt-Lee family has been elected from six states: Arizona, California, Colorado, New Mexico, Oregon, and Utah. Three Udall family cousins were nominated by the two major American political parties for the United States Senate elections of 2008, of which the two Democrats were elected and seated in 2009.
  • 1.3K
  • 25 Nov 2022
Topic Review
Carotenoids Antioxidant and Anti-Inflammatory Effects in Mood Disorders
Depression has a multifactorial etiology comprising family history and unemployment. Antioxidant supplementation has been found to combat various stress-induced psychiatric disorders, including depression and anxiety. A growing body of evidence indicates that carotenoids have both antioxidant and anti-inflammatory. Studies also suggest that poor dietary intake, particularly low intakes of fruit and vegetables and high intakes of fast food and other convenience foods, may increase the risk of developing depression. Thus, dietary interventions have the potential to help mitigate the risk of mental health decline in both the general population and those with mood disorders. 
  • 1.3K
  • 17 Mar 2023
Topic Review
Radio Signals-Based Positioning
The rapid expansion of the Internet of Things (IoT) and Machine Learning (ML) has significantly increased the demand for Location-Based Services (LBS). Among these services, indoor positioning and navigation have emerged as crucial components, driving the growth of indoor localization systems. However, using GPS in indoor environments is impractical, leading to a surge in interest in Received Signal Strength Indicator (RSSI) and machine learning-based algorithms for in-building localization and navigation.
  • 1.3K
  • 07 Jun 2023
Topic Review
EDAR Gene
Ectodysplasin A receptor: The EDAR gene provides instructions for making a protein called the ectodysplasin A receptor. 
  • 1.3K
  • 24 Dec 2020
Topic Review
Roasted Sesame Flavor Baijiu
The sesame flavor Baijiu was accidentally discovered after the founding of the People's Republic of China. Sesame flavor Baijiu is known for its special aroma of roasted sesame, which attracts people’s attention.
  • 1.3K
  • 19 Apr 2022
Topic Review
Institutional Theory and International Construction Market
International construction market is heavily affected by institutional factors. A variety of clues show that institutional factors have a complex impact on contractors’ IMS. This entry extensively collects institutional factors predicted to impact contractors’ IMS by literature review, selects 10 specific institutional factors from different perspectives, theoretically deduces their effects on contractor’s IMS, and takes international Chinese contractors’ IMS practice as the empirical research material and collects data for logistic regression analysis to test the assumptions.
  • 1.3K
  • 17 May 2022
Topic Review
Pediatric Conjunctivitis
Conjunctivitis is a common pediatric problem and is broadly divided into infectious and non-infectious etiologies. Bacterial conjunctivitis makes up the majority of cases in children and often presents with purulent discharge and mattering of the eyelids. Treatment is supportive with an individual approach to antibiotic use in uncomplicated cases since it may shorten symptom duration, but is not without risks. Viral conjunctivitis is the other infectious cause and is primarily caused by adenovirus, with a burning, gritty feeling and watery discharge. Treatment is supportive. Allergic conjunctivitis is largely seasonal and presents with bilateral itching and watery discharge. Treatment can include topical lubricants, topical antihistamine agents, or systemic antihistamines. Other causes of conjunctivitis include foreign bodies and non-allergic environmental causes. 
  • 1.3K
  • 15 May 2023
Topic Review
Natural Pozzolan in Concrete
For several decades, class F fly ash has been an attractive supplementary cementitious material, at least in part, due to its ability to reduce Portland cement consumption and mitigate alkali-silica reactions in concrete. However, fly ash availability is becoming uncertain as the energy industry decommissions coal burning power plants as it transitions to renewable energy production. This situation creates a need to identify viable and sustainable alternative supplementary cementitious materials. There are several types of supplementary cementitious materials, such as natural pozzolans, metakaolin, or ground granulated blast-furnace slag, which appear to be potential alternatives to fly ash in concrete. In this research, a locally available natural pozzolan (pumicite) was selected to replace fly ash in concrete. After conducting alkali-silica reaction tests on mortar mixtures, rheological and strength properties, shrinkage, resistance to freezing and thawing, and chloride ion permeability of concrete mixtures containing different amounts of fly ash and natural pozzolan were evaluated. The results showed that pumicite was more effective than fly ash at mitigating the alkali-silica reaction, and a pumicite content of 20% was necessary to mitigate the alkali-silica reaction. Ternary mixtures containing both pumicite and fly ash were the most effective cementitious materials combinations for mitigating the alkali-silica reaction expansion. Additionally, pumicite provided acceptable compressive strength and modulus of rupture values (greater than 4.0 MPa) that exceeded the flexural strengths provided by established mixtures containing only fly ash. Shrinkage and durability factor values for all mixtures were less than 710 μstrain and greater than 75, which are generally considered acceptable. Additionally, all mixtures with acceptable alkali-silica reaction expansions had very low chloride permeability. These results indicate that pumicite can be a reliable alternative for fly ash.
  • 1.3K
  • 16 Nov 2023
Topic Review
Histidine-Based Carriers
During the past two decades, there have been significant advances in nucleic acid carriers modified by histidines or histidine-rich domains.  There are several properties of histidines, primarily emanating from their buffering of acidic endosomes, which augment transfection.  These roles from protonated histidines include osmotic swelling with lysis of endosomes, unpacking of the carrier complex, and release of the nucleic acids to enable the carrier to interact with the endosomal membrane.  Histidines or histidine-rich peptides have been incorporated into polymers, conjugated to lipids, phages, and mesoporous silica particles, as well as formed shields around nanoparticles.  These carriers have demonstrated significant potential to import into the cytosol different forms of nucleic acids including plasmids, siRNA, and mRNA. 
  • 1.3K
  • 08 Nov 2020
Topic Review
Visualize sustainability
       The debate on definitions of sustainability and sustainable development continues is alive and well after fifty years.  What the debate reveals is that there are multiple perspectives, ideologies and projections involved, and that these concepts of hybrid ones.  This hybridity is also reflected in the long tradition of representing these concepts, as triangles, circles, systems diagrams and living organisms, among others.  In the same way that the definitions of sustainability and sustainable development have been organized by typology, these representations can also be grouped according to similar features, characteristics and etiologies.  A typology of visual representations of these concepts is important for two reasons.  The first is that it supports reflexive processes in education and communication.  The second is that it reveals the complexity and hybridity of these contested concepts.
  • 1.3K
  • 26 Oct 2020
Topic Review
BIO-Argo Float
BIO-Argo float (chlorophyll a (Chl-a), temperature, and salinity profiles) and remote sensing data (Chl-a, photosynthetic available radiation (PAR), and wind) located south of the Kuroshio current near Shikoku from September 2018 to May 2019 were used to study phytoplankton bloom and their mechanisms of development in open oceans.
  • 1.3K
  • 29 Dec 2020
Topic Review
Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a progressive disease that affects motor neurons, which are specialized nerve cells that control muscle movement. These nerve cells are found in the spinal cord and the brain. In ALS, motor neurons die (atrophy) over time, leading to muscle weakness, a loss of muscle mass, and an inability to control movement.
  • 1.3K
  • 31 Dec 2020
Topic Review
Aqueous Organic Pollutants
Advanced oxidation processes (AOPs) are regarded as effective techniques for organic contaminants removal from water and wastewater.
  • 1.3K
  • 21 Jan 2021
Topic Review
The Cytokine Storm Syndrome
The SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a high-risk viral agent involved in the recent pandemic stated worldwide by the World Health Organization. The infection is correlated to a severe systemic and respiratory disease in many cases, which is clinically treated with a multi-drug pharmacological approach. 
  • 1.3K
  • 16 Mar 2021
Topic Review
Cofilin and Neurodegeneration
Cofilin is an actin-binding protein that plays a major role in the regulation of actin dynamics, an essential cellular process. This protein has emerged as a crucial molecule for functions of the nervous system including motility and guidance of the neuronal growth cone, dendritic spine organization, axonal branching, and synaptic signalling. Recently, other important functions in cell biology such as apoptosis or the control of mitochondrial function have been attributed to cofilin. Moreover, novel mechanisms of cofilin function regulation have also been described. The activity of cofilin is controlled by complex regulatory mechanisms, with phosphorylation being the most important, since the addition of a phosphate group to cofilin renders it inactive. Due to its participation in a wide variety of key processes in the cell, cofilin has been related to a great variety of pathologies, among which neurodegenerative diseases have attracted great interest.
  • 1.3K
  • 29 Jul 2021
Topic Review
Technology for Science Education
The COVID-19 confinement has represented both opportunities and losses for education. Rarely before has any other period moved the human spirit into such discipline or submission—depending on one’s personal and emotional points of view. Both extremes have been widely influenced by external factors on each individual’s life path. Education in the sciences and engineering has encountered more issues than other disciplines due to specialized mathematical handwriting, experimental demonstrations, abstract complexity, and lab practices. 
  • 1.3K
  • 22 Sep 2021
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