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Topic Review
Virus Monitoring Strategies for Wastewater Reuse
Wastewater reclamation and reuse have the potential to supplement water supplies, offering resiliency in times of drought and helping to meet increased water demands associated with population growth. Non-potable water reuse represents the largest potential reuse market. Yet, economic constraints for new water reuse infrastructure and safety concerns due to microbial water quality, especially viral pathogen exposure, limit the widespread implementation of water reuse. Cost-effective, real-time methods to measure or indicate the viral quality of recycled water would do much to instill greater confidence in the practice.  One of the greatest challenges of water-quality monitoring is that pathogens (including viruses as well as bacteria and protozoa) are often present at concentrations high enough to present disease risks but too low for direct detection. As a result, a variety of surrogate microorganisms are used as indicators of microbial water quality. 
  • 1.3K
  • 22 Apr 2022
Topic Review
Anti-Amyloidogenic Properties of Transthyretin and Apolipoprotein E
Transthyretin (TTR) is a 55 kDa homotetrameric protein circulating in the plasma and CSF. Its main physiological function is to transport thyroid hormone thyroxine (T4) and retinol-binding protein. Apolipoprotein E (ApoE) is a 34 kDa lipid-binding and transport protein found in both serum and CSF. Amyloid formation is a pathological process associated with a wide range of degenerative disorders, including Alzheimer’s disease, Parkinson’s disease, and diabetes mellitus type 2. During disease progression, abnormal accumulation and deposition of proteinaceous material are accompanied by tissue degradation, inflammation, and dysfunction. Agents that can interfere with the process of amyloid formation or target already formed amyloid assemblies are consequently of therapeutic interest. TTR and ApoE are among the few endogenous proteins with anti-amyloidogenic activity, therefore understanding their role and mechanism of action on amyloid formation can help in developing new therapeutic strategies. 
  • 1.3K
  • 07 May 2022
Topic Review
Critical Properties of Diosmin
Because of their medicinal characteristics, effectiveness, and importance, plant-derived flavonoids have been a possible subject of research for many years, particularly in the last decade. Plants contain a huge number of flavonoids, and Diosmin, a flavone glycoside, is one of them. Numerous in-vitro and in-vivo studies have validated Diosmin’s extensive range of biological capabilities which present antioxidative, antihyperglycemic, anti-inflammatory, antimutagenic, and antiulcer properties. 
  • 1.3K
  • 16 May 2022
Topic Review
Infectious Diseases Associated with Hydrometeorological Hazards in Europe
Hydrometeorological hazards comprise a wide range of events, mainly floods, storms, droughts, and temperature extremes. Floods account for the majority of the related disasters in both developed and developing countries. Flooding alters the natural balance of the environment and frequently establishes a favorable habitat for pathogens and vectors to thrive. Diseases caused by pathogens that require vehicle transmission from host to host (waterborne) or a host/vector as part of their life cycle (vector-borne) are those most likely to be affected by flooding. 
  • 1.3K
  • 29 Aug 2022
Topic Review
Insulin and the HPA-Axis in the Metabolic Syndrome
Emerging data suggest that chromic hyperinsulinemia is also a driving force for increased activation of the hypothalamic-adrenal-pituitary (HPA) axis in subjects with the metabolic syndrome, leading to a state of “functional hypercortisolism”. This “functional hypercortisolism” by antagonizing insulin actions may prevent hypoglycemia. It also disturbs energy balance by shifting energy fluxes away from muscles toward abdominal fat stores. Synergistic effects of hyperinsulinemia and “functional hypercortisolism” promote abdominal visceral obesity and insulin resistance which are core pathophysiological components of the metabolic syndrome. It is hypothesized that hyperinsulinemia-induced increased activation of the HPA axis plays an important etiological role in the development of the metabolic syndrome and its consequences. Numerous studies have demonstrated reversibility of hyperinsulinemia with lifestyle, surgical, and pharmaceutical-based therapies. Longitudinal studies should be performed to investigate whether strategies that reduce hyperinsulinemia at an early stage are successfully in preventing increased activation of the HPA axis and the metabolic syndrome.
  • 1.3K
  • 30 Aug 2022
Topic Review
New Austrian Tunnelling Method
The New Austrian tunneling method (NATM), also known as the sequential excavation method (SEM) or sprayed concrete lining method (SCL), is a method of modern tunnel design and construction employing sophisticated monitoring to optimize various wall reinforcement techniques based on the type of rock encountered as tunneling progresses. This technique first gained attention in the 1960s based on the work of Ladislaus von Rabcewicz, Leopold Müller, and Franz Pacher between 1957 and 1965 in Austria. The name NATM was intended to distinguish it from earlier methods, with its economic advantage of employing inherent geological strength available in the surrounding rock mass to stabilize the tunnel wherever possible rather than reinforcing the entire tunnel. NATM/SEM is generally thought to have helped revolutionise the modern tunneling industry. Many modern tunnels have used this excavation technique. The works built by the Sequential Excavation Method are very attractive from the economic point of view and reasonable in karst conditions.
  • 1.3K
  • 30 Sep 2022
Topic Review
The Viscum Species for Diet and Medicinal Purposes
True mistletoe (of the Viscum species) is a semi-parasitic, perennial browse species that is found attached to its host—a shrub or a tree. It has important pharmaceutical and chemical properties that allow it to be used for a variety of purposes, including livestock production. 
  • 1.3K
  • 11 Oct 2022
Topic Review
Adjustment Disorder
Adjustment disorder (AjD) is a mental and behavioral disorder, which is a maladaptive response to a psychosocial stressor that occurs when an individual has significant difficulty adjusting to or coping with a stressful psychosocial event. The maladaptive response usually involves otherwise normal emotional and behavioral reactions that manifest more intensely than usual (taking into account contextual and cultural factors), causing marked distress, preoccupation with the stressor and its consequences, and functional impairment. Diagnosis of AjD is quite common; there is an estimated incidence of 5–21% among psychiatric consultation services for adults. Adult women are diagnosed twice as often as are adult men. Among children and adolescents, girls and boys are equally likely to receive this diagnosis.:681 AjD was introduced into the Diagnostic and Statistical Manual of Mental Disorders in 1980. Prior to that, it was called "transient situational disturbance."
  • 1.3K
  • 17 Oct 2022
Topic Review
Role of Agricultural Biomass in European Union Countries
The theoretical potential presenting the energy value of all existing agricultural biomass resources in EU countries and the technical potential taking into account agricultural biomass resources that are not used in agriculture. The research was based on Eurostat data for 2019. The conducted research shows that European Union countries are characterized by a significant potential of agricultural biomass.
  • 1.3K
  • 24 Oct 2022
Topic Review
International Workshop on Operator Theory and Its Applications
The other major branch of operator theory, Operator algebras (C* and von Neumann Algebras), is not heavily represented at IWOTA and has its own conferences. IWOTA gathers leading experts from all over the world for an intense exchange of new results, information and opinion, and for tracing the future developments in the field. The IWOTA meetings provide opportunities for participants (including young researchers) to present their own work in invited and contributed talks, to interact with other researchers from around the globe, and to broaden their knowledge of the field. In addition, IWOTA emphasizes cross-disciplinary interaction among mathematicians, electrical engineers and mathematical physicists. In the even years, the IWOTA workshop is a satellite meeting to the biennial International Symposium on the Mathematical Theory of Networks and Systems (MTNS). From the humble beginnings in the early 80's, the IWOTA workshops grew to become one of the largest continuing conferences attended by the community of researchers in operator theory.
  • 1.3K
  • 27 Oct 2022
Topic Review
Experimental Seismic Assessment of Nonstructural Elements
Nonstructural elements (NEs) are generally defined as elements typically housed within buildings/facilities that are not part of the structural system. Nonstructural elements are often classified as architectural elements, mechanical/electrical/hydraulic systems, and building contents. Nonstructural elements are often associated with critical seismic risk, due to their high vulnerability and exposure to seismic actions, especially for critical facilities such as hospitals and nuclear plant facilities. 
  • 1.3K
  • 08 Nov 2022
Topic Review
Microplastic Pollution in Coastal Area of Black Sea
Plastic materials, degraded by physical and chemical processes, become micro- and nanoparticles. Microplastic pollution is a complex problem, as it is widespread and the exact harmful effects of long and short exposure are not known, although it certainly has considerable consequences for biota, the environment, and public health. The Black Sea is becoming a strategic area as a battle front and shipping route. This certainly influences the quality of the marine environment, and its microplastic pollution could degenerate into a much more unpleasant situation. Therefore, it is important to have a picture of this pollution in the Black Sea area to facilitate future efforts to understand the impact of this crisis.
  • 1.3K
  • 17 Nov 2022
Topic Review
GIS and Environmental Governance
Geographic information system (GIS) is a commonly used tool for environmental management, modelling and planning. As simply defined by Michael Goodchild, GIS is as ‘a computer system for handling geographic information in a digital form’. In recent years it has played an integral role in participatory, collaborative and open data philosophies. Social and technological evolutions have elevated ‘digital’ and ‘environmental’ agendas to the forefront of public policy, the global media and the private sector. Government departments routinely use digital spatial platforms to plan and model proposed changes to road networks, building design, greenbelt land, utility provision, crime prevention, energy production, waste management and security. Non-profit organizations also incorporate geospatial and web-mapping approaches into political campaigns to lobby governments, to protest against socially or environmentally harmful companies, and to generate public support. Private business, whether in land management, resource extraction, retail, manufacturing or social media for example, also incorporate GIS into overall profit-making strategies.
  • 1.3K
  • 15 Nov 2022
Topic Review
Thermodynamics and an Introduction to Thermostatistics
Thermodynamics and an Introduction to Thermostatistics is a textbook written by Herbert Callen that explains the basics of classical thermodynamics and discusses advanced topics in both classical and quantum frameworks. The textbook contains three parts, each building upon the previous. The first edition was published in 1960 and a second followed in 1985.
  • 1.3K
  • 22 Nov 2022
Topic Review
Health Effects of Pesticides
Health effects of pesticides may be acute or delayed in those who are exposed. Acute effects can include pesticide poisoning, which may be a medical emergency. Strong evidence exists for other, long-term negative health outcomes from pesticide exposure including birth defects, fetal death, neurodevelopmental disorder, cancer, and neurologic illness including Parkinson's disease. Toxicity of pesticides depend on the type of chemical, route of exposure, dosage, and timing of exposure. According to The Stockholm Convention on Persistent Organic Pollutants (2001), 9 of the 12 most dangerous and persistent chemicals were pesticides, so many have now been withdrawn from use.
  • 1.3K
  • 25 Nov 2022
Topic Review
Diagnosis of Bovine Tuberculosis
Bovine tuberculosis is a serious infectious disease affecting a wide range of domesticated and wild animals, representing a worldwide economic and public health burden. The disease is caused by Mycobacterium bovis and infrequently by other pathogenic mycobacteria. The problem of bovine tuberculosis is complicated when the infection is associated with multidrug and extensively drug resistant M. bovis. Many techniques are used for early diagnosis of bovine tuberculosis, either being antemortem or postmortem, each with its diagnostic merits as well as limitations. Antemortem techniques depend either on cellular or on humoral immune responses, while postmortem diagnosis depends on adequate visual inspection, palpation, and subsequent diagnostic procedures such as bacterial isolation, characteristic histopathology, and PCR to reach the final diagnosis.
  • 1.3K
  • 16 Dec 2022
Topic Review
Plastic Mulch Materials
Mulches can be defined as materials that are applied or grow on the soil surface (the latter are the living mulches), in contrast to soil-incorporated materials. The use of plastic mulch films is widespread in agriculture for specialty cropping systems because of several benefits. 
  • 1.3K
  • 28 Jan 2023
Topic Review
COVID-19 Vaccination in Patients with Malignant Disease
Vaccination plays an important role in the prevention of infection and subsequent severe COVID-19 among the general population. Compared to the general population, patients with malignancy are more likely to develop a less proficient immune response upon vaccination. This is mainly caused by disease-associated or therapy-led immune deficiency. Therefore, patients with cancer are usually prioritized for vaccinations but excluded from registration in clinical trials. 
  • 1.3K
  • 02 Mar 2023
Topic Review
Spider–Plant Associations
Spiders are ubiquitous generalist predators playing an important role in regulating insect populations in many ecosystems. Traditionally they have not been thought to have strong influences on, or interactions with plants. However, this is slowly changing as several species of cursorial spiders have been reported engaging in either herbivory or inhabiting only one, or a handful of related plant species. 
  • 1.3K
  • 15 Mar 2023
Topic Review
Solar Photovoltaic Tracking Systems
Maximum solar power can be generated only when the Sun is perpendicular to the solar panel, which can be achieved only for a few hours when using a fixed solar panel system, hence the development of an automatic solar tracking system. Over the years, different solar tracking systems have been proposed and developed.
  • 1.3K
  • 26 Apr 2023
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