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Topic Review
Eosinophil Peroxidase Deficiency
Eosinophil peroxidase deficiency is a condition that affects certain white blood cells called eosinophils but causes no health problems in affected individuals. Eosinophils aid in the body's immune response.
  • 761
  • 25 Dec 2020
Topic Review
ELOVL2-Based Epigenetic Clock for Forensic Age Prediction
The prediction of chronological age from methylation-based biomarkers represents one of the most promising applications in the field of forensic sciences. Age-prediction models developed are not easily applicable for forensic caseworkers. Among the several attempts to pursue this objective, the formulation of single-locus models might represent a good strategy.
  • 761
  • 09 Feb 2023
Topic Review
Non-Specific Lipid Transfer Proteins (nsLTPs)
Non-specific lipid transfer proteins (nsLTPs) stand out among plant-specific peptide superfamilies due to their multifaceted roles in plant molecular physiology and development, including their protective functions against pathogens. These antimicrobial agents have demonstrated remarkable efficacy against bacterial and fungal pathogens. The discovery of plant-originated, cysteine-rich antimicrobial peptides such as nsLTPs has paved the way for exploring the mentioned organisms as potential biofactories for synthesizing antimicrobial compounds.
  • 761
  • 25 May 2023
Topic Review
HOXA13 Gene
Homeobox A13
  • 760
  • 23 Dec 2020
Topic Review
Holt-Oram Syndrome
Holt-Oram syndrome is characterized by skeletal abnormalities of the hands and arms (upper limbs) and heart problems.
  • 760
  • 23 Dec 2020
Topic Review
Craniometaphyseal Dysplasia
Craniometaphyseal dysplasia is a rare condition characterized by thickening (overgrowth) of bones in the skull (cranium) and abnormalities in a region at the end of long bones known as the metaphysis. The abnormal bone growth continues throughout life. Except in the most severe cases, the lifespan of people with craniometaphyseal dysplasia is normal.
  • 760
  • 24 Dec 2020
Topic Review
CARD11 Gene
caspase recruitment domain family member 11
  • 760
  • 24 Dec 2020
Topic Review
PEPD Gene
peptidase D
  • 760
  • 25 Dec 2020
Topic Review
ITM2B Gene
Integral membrane protein 2B
  • 759
  • 23 Dec 2020
Topic Review
Limb-Girdle Muscular Dystrophy
Limb-girdle muscular dystrophy is a term for a group of diseases that cause weakness and wasting of the muscles in the arms and legs. The muscles most affected are those closest to the body (proximal muscles), specifically the muscles of the shoulders, upper arms, pelvic area, and thighs.
  • 759
  • 24 Dec 2020
Topic Review
CACNB4 Gene
calcium voltage-gated channel auxiliary subunit beta 4
  • 759
  • 24 Dec 2020
Topic Review
SETBP1 Gene
SET binding protein 1
  • 759
  • 24 Dec 2020
Topic Review
MED12 Gene
mediator complex subunit 12
  • 758
  • 22 Dec 2020
Topic Review
Hereditary Multiple Osteochondromas
Hereditary multiple osteochondromas is a condition in which people develop multiple benign (noncancerous) bone tumors called osteochondromas.
  • 758
  • 23 Dec 2020
Topic Review
MBD5 Gene
Methyl-CpG binding domain protein 5
  • 758
  • 23 Dec 2020
Topic Review
WDR45 Gene
WD repeat domain 45.
  • 758
  • 24 Dec 2020
Topic Review
ANOS1 Gene
anosmin 1
  • 758
  • 24 Dec 2020
Topic Review
Permanent Neonatal Diabetes Mellitus
Permanent neonatal diabetes mellitus is a type of diabetes that first appears within the first 6 months of life and persists throughout the lifespan.
  • 758
  • 24 Dec 2020
Topic Review
Genetic Control of Avian Migration
Twice-a-year, large-scale movement of billions of birds across latitudinal gradients is one of the most fascinating behavioral phenomena seen among animals. These seasonal voyages in autumn southwards and in spring northwards occur within a discrete time window and, as part of an overall annual itinerary, involve close interaction of the endogenous rhythm at several levels with prevailing photoperiod and temperature. The overall success of seasonal migrations thus depends on their close coupling with the other annual sub-cycles, namely those of the breeding, post-breeding recovery, molt and non-migratory periods. There are striking alterations in the daily behavior and physiology with the onset and end of the migratory period, as shown by the phase inversions in behavioral (a diurnal passerine bird becomes nocturnal and flies at night) and neural activities. Interestingly, there are also differences in the behavior, physiology and regulatory strategies between autumn and spring (vernal) migrations. Concurrent molecular changes occur in regulatory (brain) and metabolic (liver, flight muscle) tissues, as shown in the expression of genes particularly associated with 24 h timekeeping, fat accumulation and the overall metabolism.
  • 758
  • 16 Jun 2023
Topic Review
Hypermanganesemia with Dystonia
Hypermanganesemia with dystonia is an inherited disorder in which excessive amounts of the element manganese accumulate in the body (hypermanganesemia).
  • 757
  • 23 Dec 2020
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