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Xu, R. Permanent Neonatal Diabetes Mellitus. Encyclopedia. Available online: https://encyclopedia.pub/entry/5270 (accessed on 22 September 2026).
Xu R. Permanent Neonatal Diabetes Mellitus. Encyclopedia. Available at: https://encyclopedia.pub/entry/5270. Accessed September 22, 2026.
Xu, Rita. "Permanent Neonatal Diabetes Mellitus" Encyclopedia, https://encyclopedia.pub/entry/5270 (accessed September 22, 2026).
Xu, R. (2020, December 24). Permanent Neonatal Diabetes Mellitus. In Encyclopedia. https://encyclopedia.pub/entry/5270
Xu, Rita. "Permanent Neonatal Diabetes Mellitus." Encyclopedia. Web. 24 December, 2020.
Permanent Neonatal Diabetes Mellitus
Edit

Permanent neonatal diabetes mellitus is a type of diabetes that first appears within the first 6 months of life and persists throughout the lifespan.

genetic conditions

References

  1. Barbarini DS, Haslinger V, Schmidt K, Patch AM, Müller G, Simma B. Neonataldiabetes mellitus due to pancreas agenesis: a new case report and review of theliterature. Pediatr Diabetes. 2009 Nov;10(7):487-91. doi:10.1111/j.1399-5448.2009.00523.x.
  2. Edghill EL, Flanagan SE, Ellard S. Permanent neonatal diabetes due toactivating mutations in ABCC8 and KCNJ11. Rev Endocr Metab Disord. 2010Sep;11(3):193-8. doi: 10.1007/s11154-010-9149-x. Review.
  3. Edghill EL, Flanagan SE, Patch AM, Boustred C, Parrish A, Shields B, Shepherd MH, Hussain K, Kapoor RR, Malecki M, MacDonald MJ, Støy J, Steiner DF, Philipson LH, Bell GI; Neonatal Diabetes International Collaborative Group, Hattersley AT, Ellard S. Insulin mutation screening in 1,044 patients with diabetes: mutationsin the INS gene are a common cause of neonatal diabetes but a rare cause ofdiabetes diagnosed in childhood or adulthood. Diabetes. 2008 Apr;57(4):1034-42.
  4. Ellard S, Flanagan SE, Girard CA, Patch AM, Harries LW, Parrish A, Edghill EL,Mackay DJ, Proks P, Shimomura K, Haberland H, Carson DJ, Shield JP, HattersleyAT, Ashcroft FM. Permanent neonatal diabetes caused by dominant, recessive, orcompound heterozygous SUR1 mutations with opposite functional effects. Am J HumGenet. 2007 Aug;81(2):375-82.
  5. Flanagan SE, Clauin S, Bellanné-Chantelot C, de Lonlay P, Harries LW, GloynAL, Ellard S. Update of mutations in the genes encoding the pancreatic beta-cell K(ATP) channel subunits Kir6.2 (KCNJ11) and sulfonylurea receptor 1 (ABCC8) indiabetes mellitus and hyperinsulinism. Hum Mutat. 2009 Feb;30(2):170-80. doi:10.1002/humu.20838. Review.
  6. Flanagan SE, Edghill EL, Gloyn AL, Ellard S, Hattersley AT. Mutations inKCNJ11, which encodes Kir6.2, are a common cause of diabetes diagnosed in thefirst 6 months of life, with the phenotype determined by genotype. Diabetologia. 2006 Jun;49(6):1190-7.
  7. Malecki MT, Mlynarski W. Monogenic diabetes: implications for therapy of rare types of disease. Diabetes Obes Metab. 2008 Aug;10(8):607-16.Review.
  8. Osbak KK, Colclough K, Saint-Martin C, Beer NL, Bellanné-Chantelot C, EllardS, Gloyn AL. Update on mutations in glucokinase (GCK), which cause maturity-onsetdiabetes of the young, permanent neonatal diabetes, and hyperinsulinemichypoglycemia. Hum Mutat. 2009 Nov;30(11):1512-26. doi: 10.1002/humu.21110.Review.
  9. Polak M, Cavé H. Neonatal diabetes mellitus: a disease linked to multiplemechanisms. Orphanet J Rare Dis. 2007 Mar 9;2:12. Review.
  10. Rubio-Cabezas O, Klupa T, Malecki MT; CEED3 Consortium. Permanent neonataldiabetes mellitus--the importance of diabetes differential diagnosis in neonates and infants. Eur J Clin Invest. 2011 Mar;41(3):323-33. doi:10.1111/j.1365-2362.2010.02409.x.
  11. Støy J, Steiner DF, Park SY, Ye H, Philipson LH, Bell GI. Clinical andmolecular genetics of neonatal diabetes due to mutations in the insulin gene. RevEndocr Metab Disord. 2010 Sep;11(3):205-15. doi: 10.1007/s11154-010-9151-3.Review. Erratum in: Rev Endocr Metab Disord. 2012 Mar;13(1):79-81.
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