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O-GlcNAc Regulates Primary Cilium Length during Neuronal Development
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  • View Times: 49
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  • Update Date: 02 Jun 2023
  • O-GlcNAc
  • primary cilia
  • neuronal development
  • cortical neurons
  • human induced-pluripotent stem cells
Video Introduction

This video is adapted from 10.3390/cells12111520

The primary cilium plays critical roles in the homeostasis and development of neurons. Recent studies demonstrate that cilium length is regulated by the metabolic state of cells, as dictated by processes such as glucose flux and O-GlcNAcylation (OGN). The study of cilium length regulation during neuron development, has been an area left largely unexplored. This project aims to elucidate the roles of O-GlcNAc in neuronal development through its regulation of the primary cilium.

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Tian, J.; Huang, C.; Eslami, F.; Mannino, M.P.; Mai, R.L.; Hart, G.W. O-GlcNAc Regulates Primary Cilium Length during Neuronal Development. Encyclopedia. Available online: https://encyclopedia.pub/video/video_detail/746 (accessed on 05 December 2025).
Tian J, Huang C, Eslami F, Mannino MP, Mai RL, Hart GW. O-GlcNAc Regulates Primary Cilium Length during Neuronal Development. Encyclopedia. Available at: https://encyclopedia.pub/video/video_detail/746. Accessed December 05, 2025.
Tian, Jie, Chia-Wei Huang, Farzad Eslami, Michael Philip Mannino, Rebecca Lee Mai, Gerald W. Hart. "O-GlcNAc Regulates Primary Cilium Length during Neuronal Development" Encyclopedia, https://encyclopedia.pub/video/video_detail/746 (accessed December 05, 2025).
Tian, J., Huang, C., Eslami, F., Mannino, M.P., Mai, R.L., & Hart, G.W. (2023, June 01). O-GlcNAc Regulates Primary Cilium Length during Neuronal Development. In Encyclopedia. https://encyclopedia.pub/video/video_detail/746
Tian, Jie, et al. "O-GlcNAc Regulates Primary Cilium Length during Neuronal Development." Encyclopedia. Web. 01 June, 2023.
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