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Human Neural Stem Cells and Brain Tumor-Initiating Cells
- Subjects: Neurosciences
- |
- Contributors:
- Sergey Malchenko ,
- Jerusha Boyineni ,
- Jason Michael Wood ,
- Aditya Ravindra ,
- Ethan Boley ,
- Sarah E. Donohue ,
- Marcelo Bento Soares
- neural stem cells
- cancer stem cells
- astrocytes
- intercellular mitochondrial transfer
Video Introduction
This video is adapted from 10.3390/cells13030204
The communication between neural stem cells (NSCs) and surrounding astrocytes is essential for the homeostasis of the NSC niche. Intercellular mitochondrial transfer, a unique communication system that utilizes the formation of tunneling nanotubes for targeted mitochondrial transfer between donor and recipient cells, has recently been identified in a wide range of cell types. Intercellular mitochondrial transfer has also been observed between different types of cancer stem cells (CSCs) and their neighboring cells, including brain CSCs and astrocytes. CSC mitochondrial transfer significantly enhances overall tumor progression by reprogramming neighboring cells.
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Malchenko, S.; Boyineni, J.; Wood, J.M.; Ravindra, A.; Boley, E.; Donohue, S.E.; Soares, M.B. Human Neural Stem Cells and Brain Tumor-Initiating Cells. Encyclopedia. Available online: https://encyclopedia.pub/video/video_detail/1100 (accessed on 05 December 2025).
Malchenko S, Boyineni J, Wood JM, Ravindra A, Boley E, Donohue SE, et al. Human Neural Stem Cells and Brain Tumor-Initiating Cells. Encyclopedia. Available at: https://encyclopedia.pub/video/video_detail/1100. Accessed December 05, 2025.
Malchenko, Sergey, Jerusha Boyineni, Jason Michael Wood, Aditya Ravindra, Ethan Boley, Sarah E. Donohue, Marcelo Bento Soares. "Human Neural Stem Cells and Brain Tumor-Initiating Cells" Encyclopedia, https://encyclopedia.pub/video/video_detail/1100 (accessed December 05, 2025).
Malchenko, S., Boyineni, J., Wood, J.M., Ravindra, A., Boley, E., Donohue, S.E., & Soares, M.B. (2024, February 07). Human Neural Stem Cells and Brain Tumor-Initiating Cells. In Encyclopedia. https://encyclopedia.pub/video/video_detail/1100
Malchenko, Sergey, et al. "Human Neural Stem Cells and Brain Tumor-Initiating Cells." Encyclopedia. Web. 07 February, 2024.
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