Topic Review
ZAP70-related Severe Combined Immunodeficiency
ZAP70-related severe combined immunodeficiency (SCID) is an inherited disorder that damages the immune system.
  • 378
  • 24 Dec 2020
Topic Review
ZAP70 Gene
Zeta chain of T cell receptor associated protein kinase 70
  • 273
  • 24 Dec 2020
Topic Review
YY1AP1 Gene
YY1 associated protein 1: the YY1AP1 gene provides instructions for making part of a group of associated proteins known as the INO80 chromatin remodeling complex. 
  • 363
  • 24 Dec 2020
Topic Review
YWHAE Gene
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon
  • 488
  • 24 Dec 2020
Topic Review
Yuan-Harel-Lupski Syndrome
Yuan-Harel-Lupski (YUHAL) syndrome is a rare neurological condition that has a combination of features of two other disorders, Potocki-Lupski syndrome and type 1A Charcot-Marie-Tooth disease.  
  • 726
  • 24 Dec 2020
Topic Review
Yao Syndrome
Yao syndrome (formerly called NOD2-associated autoinflammatory disease) is a disorder involving episodes of fever and abnormal inflammation affecting many parts of the body, particularly the skin, joints, and gastrointestinal system.
  • 955
  • 24 Dec 2020
Topic Review
Y Chromosome Infertility
Y chromosome infertility is a condition that affects the production of sperm and causes male infertility, which means it is difficult or impossible for affected men to father children.
  • 432
  • 24 Dec 2020
Topic Review
Y Chromosome Evolution and Functional Specialization
The Y chromosome is one of the sex chromosomes found in males of animals of different taxa, including insects and mammals. Among all chromosomes, the Y chromosome is characterized by a unique chromatin landscape undergoing dynamic evolutionary change. Being entirely heterochromatic, the Y chromosome as a rule preserves few functional genes, but is enriched in tandem repeats and transposons. Due to difficulties in the assembly of the highly repetitive Y chromosome sequence, deep analyses of Y chromosome evolution, structure, and functions are limited to a few species, one of them being Drosophila melanogaster. Here researchers survey comparative evolutionary history of the fly and human Y chromosomes, and functions of Y-linked piRNA clusters ensuring sex-specific piRNA silencing. 
  • 1.1K
  • 09 May 2022
Topic Review
XPC Gene
XPC complex subunit, DNA damage recognition and repair factor: the XPC gene provides instructions for making a protein that is involved in repairing damaged DNA. 
  • 429
  • 24 Dec 2020
Topic Review
XPA Gene
XPA, DNA damage recognition and repair factor: The XPA gene provides instructions for making a protein that is involved in repairing damaged DNA. DNA can be damaged by ultraviolet (UV) rays from the sun and by toxic chemicals, radiation, and unstable molecules called free radicals.
  • 400
  • 24 Dec 2020
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