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Tang, P. XPA Gene. Encyclopedia. Available online: https://encyclopedia.pub/entry/4631 (accessed on 28 September 2026).
Tang P. XPA Gene. Encyclopedia. Available at: https://encyclopedia.pub/entry/4631. Accessed September 28, 2026.
Tang, Peter. "XPA Gene" Encyclopedia, https://encyclopedia.pub/entry/4631 (accessed September 28, 2026).
Tang, P. (2020, December 24). XPA Gene. In Encyclopedia. https://encyclopedia.pub/entry/4631
Tang, Peter. "XPA Gene." Encyclopedia. Web. 24 December, 2020.
XPA Gene
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This entry is adapted from the peer-reviewed paper https://medlineplus.gov/genetics/gene/xpa

XPA, DNA damage recognition and repair factor: The XPA gene provides instructions for making a protein that is involved in repairing damaged DNA. DNA can be damaged by ultraviolet (UV) rays from the sun and by toxic chemicals, radiation, and unstable molecules called free radicals.

genes

References

  1. Camenisch U, Nägeli H. XPA gene, its product and biological roles. Adv Exp MedBiol. 2008;637:28-38. Review.
  2. Cleaver JE, States JC. The DNA damage-recognition problem in human and othereukaryotic cells: the XPA damage binding protein. Biochem J. 1997 Nov 15;328 ( Pt1):1-12. Review.
  3. Cleaver JE, Thompson LH, Richardson AS, States JC. A summary of mutations inthe UV-sensitive disorders: xeroderma pigmentosum, Cockayne syndrome, andtrichothiodystrophy. Hum Mutat. 1999;14(1):9-22. Review.
  4. Hirai Y, Kodama Y, Moriwaki S, Noda A, Cullings HM, Macphee DG, Kodama K,Mabuchi K, Kraemer KH, Land CE, Nakamura N. Heterozygous individuals bearing afounder mutation in the XPA DNA repair gene comprise nearly 1% of the Japanesepopulation. Mutat Res. 2006 Oct 10;601(1-2):171-8.
  5. Jones CJ, Wood RD. Preferential binding of the xeroderma pigmentosum group Acomplementing protein to damaged DNA. Biochemistry. 1993 Nov 16;32(45):12096-104.
  6. Satokata I, Iwai K, Matsuda T, Okada Y, Tanaka K. Genomic characterization of the human DNA excision repair-controlling gene XPAC. Gene. 1993 Dec22;136(1-2):345-8.
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Subjects: Genetics & Heredity
Contributor MDPI registered users' name will be linked to their SciProfiles pages. To register with us, please refer to https://encyclopedia.pub/register : Peter Tang
View Times: 813
Entry Collection: MedlinePlus
Revision: 1 time (View History)
Update Date: 24 Dec 2020
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