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Biography
Gottfried Heinisch
On 19 September 2019, the Pharmaceutical Science community in Austria lost a distinguished luminary, O. Univ.-Prof.i.R. Dr. Dr.h.c. Mag. pharm. Gottfried Heinisch, at the age of eighty after a long, severe illness. Born in 1938 to a Lower-Austrian Pharmacist’s family, Gottfried Heinisch studied pharmaceutical sciences at the University of Vienna, initially with the perspective of becoming a P
  • 414
  • 13 Sep 2022
Topic Review
Gold/Silver Nanoparticles Antimicrobial Applications
Currently, metal nanoparticles have varied uses for different medical, pharmaceutical, and agricultural applications. Nanobiotechnology, combined with green chemistry, has great potential for the development of novel and necessary products that benefit human health, environment, and industries. Green chemistry has an important role due to its contribution to unconventional synthesis methods of gold and silver nanoparticles from plant extracts, which have exhibited antimicrobial potential, among other outstanding properties. Biodiversity-rich countries need to collect and convert knowledge from biological resources into processes, compounds, methods, and tools, which need to be achieved along with sustainable use and exploitation of biological diversity. Green synthesis of gold and silver nanoparticles from plant extracts can be applied as antimicrobial agents within the agricultural field for fighting against bacterial and fungal pathogens that can cause plant, waterborne, and foodborne diseases.
  • 980
  • 27 Oct 2020
Topic Review
Gold(I)-Catalyzed Approaches with Arylalkyne Activation
Gold catalysts possess the advantages of water and oxygen resistance, with the possibility of catalyzing many novel chemical transformations, especially in the syntheses of small-molecule skeletons, in addition to achieving the rapid construction of multiple chemical bonds and ring systems in one step.
  • 756
  • 14 Feb 2023
Topic Review
Gold-Nanoparticle Hybrid Nanostructures for Multimodal Cancer Therapy
With the urgent need for bio-nanomaterials to improve the currently available cancer treatments, gold nanoparticle (GNP) hybrid nanostructures are rapidly rising as promising multimodal candidates for cancer therapy. Gold nanoparticles (GNPs) have been hybridized with several nanocarriers, including liposomes and polymers, to achieve chemotherapy, photothermal therapy, radiotherapy, and imaging using a single composite. The GNP nanohybrids used for targeted chemotherapy can be designed to respond to external stimuli such as heat or internal stimuli such as intratumoral pH. 
  • 451
  • 28 Oct 2022
Topic Review
Gold Nanoparticles: The Guest
Gold nanoparticles (AuNP) have received a growing attention due to their fascinating physiochemical properties and promising range of biomedical applications including sensing, diagnosis and cancer photothermal ablation. AuNP enjoy brilliant optical properties and ability to convert light into local heat and function as a “nanoheaters” to fight cancer. However, AuNP are poor drug delivery systems as they do not have reservoirs or matrices to achieve an acceptable drug loading efficiency. On the other end, liposome-based nanocarriers do not exhibit such optical properties but are excellent platform for drug loading and they have been proven clinically with a true presence in the market since the FDA approved Doxil® in 1995. 
  • 208
  • 20 Jul 2023
Topic Review
Gold Nanoparticles Functionalized with Natural Compounds from Plants
Biosynthesis of gold nanoparticles (AuNPs) has been widely studied and described. In the age of bacterial drug resistance, an intensive search for new agents with antibacterial properties or a new form of antibiotics with effective action is necessary.
  • 677
  • 12 Dec 2022
Topic Review
Gold Nanoparticles for Multidrug-Resistant Bacteria
The field of medical nanotechnology has emerged as an innovative and a powerful tool for treating some of the most complicated health conditions. Different inorganic nanomaterials including gold, silver, and others have showed potential antibacterial efficacies. Interestingly, gold nanoparticles (AuNPs) have gained specific attention, due to their biocompatibility, ease of surface functionalization, and their optical properties.
  • 997
  • 22 Feb 2021
Topic Review
Gold Nanoparticles and Their Biomedical Applications
Gold nanoparticles (AuNPs) have the ability to absorb and scatter light, and can convert optical energy into heat using nonradiative electron relaxation dynamics and surface chemistry. Moreover, gold nanoparticles can be used as drug carriers, making them very attractive and versatile nanoparticles. The features of AuNPs that make them particularly attractive in biomedicine are their excellent stability and biocompatibility, ease to functionalize their surfaces, their low toxicity, and their drug transferability. Other features, such as shape and size adaptation, have certainly drawn attention for the use of gold nanoparticles in many fields.
  • 999
  • 19 May 2022
Topic Review
Gold Nanoparticle-Based Combined Cancer Therapy
The integrated development of innovative nanoparticle (NP) based approaches will be a key to address one of the main issues in both radiotherapy and chemotherapy: normal tissue toxicity. Among other inorganic NP systems, gold nanoparticle (GNP) based systems offer the means to further improve chemotherapy through controlled delivery of chemotherapeutics, while local radiotherapy dose can be enhanced by targeting the GNPs to the tumor.
  • 1.1K
  • 31 Aug 2020
Topic Review
Gold Nanoclusters in Tumor Theranostic and Combination Therapy
The rising incidence and severity of malignant tumors threaten human life and health, and the current lagged diagnosis and single treatment in clinical practice are inadequate for tumor management. Gold nanoclusters (AuNCs) are nanomaterials with small dimensions (≤3 nm) and few atoms exhibiting unique optoelectronic and physicochemical characteristics, such as fluorescence, photothermal effects, radiosensitization, and biocompatibility.
  • 387
  • 02 Dec 2022
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