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Topic Review
Caregiving in Parkinson´s Disease and Deep Brain Stimulation
In Parkinson’s disease (PD) patients, the progressive nature of the disease and the variability of disabling motor and non-motor symptoms contribute to the growing caregiver burden (CB) of PD partners and conflicts in their relationships. In advanced stages of the disease, Deep Brain Stimulation (DBS) improves PD symptoms and patients quality of life but the effect of DBS on CB of PD partners seems to be heterogeneous. The CB in the context of DBS framing both pre-, peri- and postoperative aspects aims to be illuminated, and further recognition of caregiver burden in partners of PD patients with DBS will be stimulated.
  • 591
  • 18 Feb 2022
Topic Review
Self-Care Research
Background: Theories can provide a foundation to explain behavior, investigate relationships, and to predict the effect of interventions. The aim of the study was to clarify the use of theories in studies testing interventions to promote self-care. Method: A scoping review. PubMed, EMBASE, PsychINFO, and CINAHL were searched from January 2008 through January 2019. Nine common chronic conditions were included. We included studies testing a self-care intervention if they used a randomized controlled trial design. 
  • 591
  • 08 Jan 2021
Topic Review
Screening, Stratification and Scores
Technological innovations including risk-stratification algorithms and large databases of longitudinal population health data and genetic data are allowing us to develop a deeper understanding how individual behaviors, characteristics, and genetics are related to health risk. The clinical implementation of risk-stratified screening programmes that utilise risk scores to allocate patients into tiers of health risk is foreseeable in the future.
  • 590
  • 13 Aug 2021
Topic Review
The Bacterial Urban Resistome
Cities that are densely populated are reservoirs of antibiotic resistant genes (ARGs). The overall presence of all resistance genes in a specific environment is defined as a resistome. Spatial proximity of surfaces and different hygienic conditions leads to the transfer of antibiotic resistant bacteria (ARB) within urban environments. Built environments, public transportation, green spaces, and citizens’ behaviors all support persistence and transfer of antimicrobial resistances (AMR). 
  • 590
  • 14 Jun 2022
Topic Review
Use of Digital Mental Health Platforms and Interventions
The increasing use of digital mental health (DMH) platforms and digital mental health interventions (DMHIs) is hindered by uncertainty over effectiveness, quality and usability. There is a need to identify the types of available evidence in this domain. There was a small amount of significant evidence (1 in each 11), notably the (cost-)effectiveness of a DMHI with significant long-term impact on anxiety and depression in adults. Empirical research has demonstrated the feasibility of DMH platforms and DMHIs. 
  • 590
  • 06 Jan 2023
Topic Review
Health Effects of Red Wine Consumption
A strong controversy persists regarding the effect of red wine (RW) consumption and health. Guidelines for the prevention of cardiovascular diseases (CVD) and cancers discourage alcohol consumption in any form, but several studies have demonstrated that low RW intake may have positive effects on CVD risk. 
  • 589
  • 27 Apr 2023
Topic Review
Steroid Induced Hyperglycaemia in Hospital
Oral hypoglycaemic agents (OHAs) might be an adequate choice in inpatients with stable and non-critical disease and mild hyperglycaemic excursions. In those with significant hyperglycaemia and severe illness, insulin remains the treatment of choice in the hospital setting as also suggested by the current guidelines for inpatient diabetes management.
  • 589
  • 21 Jun 2021
Topic Review
Safety Culture
Safety culture is considered to be the result of personal and collective attitudes, beliefs, and behaviour patterns, and it determines the commitment, willingness, style, and ability of organizations to manage health and safety issues. 
  • 588
  • 20 Aug 2021
Topic Review
Omega-3 PUFA in Pediatric Cancer
Epidemiological literature suggests a protective effect of omega-3 (n-3) polyunsaturated fatty acids (PUFAs) against cancer. They are attributed to have significant anti-inflammatory properties, and are reported to directly inhibit carcinogenesis and tumor expansion, whilst also reducing the risk for secondary complications, thus representing a promising approach for adjunctive chemotherapy treatment. At the same time, the incidence of malnutrition amongst children with cancer is high and both under- and overnutrition are associated with detrimental consequences, including increased risks for morbidity and mortality, early relapse rates, and a higher prevalence of secondary complications during treatment. Taken together with the benefits of n-3 PUFA supplementation, an enhancement of the nutritional status is a potentially modifiable prognostic factor in pediatric oncology.
  • 587
  • 08 Jun 2021
Topic Review
Sleep Duration and Waking Activities
Optimal sleep duration is crucial as both short and long sleep duration are associated with physical and mental health problems. For example, sleep duration that is considered to be too short has been linked with an increased risk of obesity, hypertension, cardiovascular disease, and type II diabetes, whereas sleep duration that is too long has been associated with an increased risk of poor health-related quality of life, multiple sclerosis, cardiovascular disease, and stroke.
  • 587
  • 24 Jun 2021
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