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All Topic Review Biography
Topic Review
Digital Health Interventions by Clinical Pharmacists
Integrating digital interventions in healthcare has gained increasing popularity among clinical pharmacists (CPs) due to advances in technology. Although the impacts of telephone-based interventions on patients’ outcomes were decidedly mixed, web-based interventions and mobile apps exerted generally positive influences.
  • 497
  • 26 Jan 2022
Topic Review
Anti-CCR5 Therapy, Breast Cancer and Its Microenvironment
Breast cancer represents the most common malignancy among women in the world. The local microenvironment around the tumor plays a great role in cancer progression and invasion, representing a promising therapeutic target. CCL5 is a potent chemokine with a physiological role of immune cell attraction and has gained particular attention in R&D for breast cancer treatment. Its receptor, CCR5, is a well-known co-factor for HIV entry through the cell membrane and CCR5 blocking represents a mainstay of HIV treatment. Interestingly, CCL5 is currently described as key pro-oncogenic factor, especially in breast cancer. Several studies blocking the CCL5/CCR5 axis show cancer cells become less invasive and less malignant, with less oncogenic extracellular matrices.
  • 496
  • 28 Nov 2022
Topic Review
Parent–Child Interactions in Deafness Children
Despite early identification and advancements in cochlear implant and hearing aid technology, delays in language skills in deaf children continue to exist. Good-quality parent–child interaction (PCI) is a key predictor for the successful development of deaf children’s signed and/or spoken language. As good-quality PCI is widely acknowledged to be significant for child language development in deaf children, then we must have the necessary tools to assess it. This review answers three questions: Which parent behaviours are assessed in PCI? How are they assessed? And which parent interaction behaviours are positively correlated with deaf children's language skills?
  • 496
  • 03 Sep 2021
Topic Review
Participatory Action Research for Sexual and Reproductive Health
Youth-friendly sexual and reproductive health (SRH) interventions are essential for the health of adolescents (10–19 years). Co-designing is a participatory approach to research, allowing for collaboration with academic and non-academic stakeholders in intervention development. Participatory action research (PAR) involves stakeholders throughout the planning, action, observation, and reflection stages of research. Current knowledge indicates that co-producing SRH interventions with adolescents increases a feeling of ownership, setting the scene for intervention adoption in implementation settings. 
  • 495
  • 10 Mar 2022
Topic Review
Work-Related Impacts of Cancer Caregiving
Individuals with cancer commonly rely on their informal caregivers (e.g., spouse/partner, family member, close friend) to help them manage the demands of the disease and its treatment. Caregiving, including helping with patient care, performing household chores, and providing emotional and practical support, can be particularly demanding for employed caregivers, who must juggle their work responsibilities while providing care. The work-related impacts of informal cancer caregiving that have been investigated in the literature include: (1) labor market withdrawal to provide care, (2) work modifications, (3) absenteeism, and, (4) presenteeism.
  • 495
  • 08 Sep 2022
Topic Review
Evaluation of Urban Cooling Interventions
Heat islands and warming temperatures are a growing global public health concern. Cities worldwide are implementing heat adaptation and mitigation interventions to reduce the urban heat island effect and extreme heat exposures. As listed by the Environmental Protection Agency (USA EPA), these interventions may include: trees/vegetation, green and cool roofs, cool pavements, and broadly improved infrastructure that invests in ‘greener’ practices. Although cities are implementing cooling interventions, little is known about their efficacy. Four interventions often used in urban areas are taken into consideration here: cooling centers, misting stations, cool (or green) roofs, and cool pavements.
  • 495
  • 01 Aug 2022
Topic Review
Food Choice Editing in Favor of Sustainability
A vast literature has confirmed that, in several economies, sustainability is a prevailing key problem, particularly in the agri-food industry. Consumers frequently like to associate themselves with sustainable items reflecting higher concern for society, healthy food, or commodities exhibiting greater fairness towards food producers. Worldwide, there is an increased awareness of consumption patterns escalating the demand for the production of sustainable items. Researchers revealed that change interventions have slowly reduced the pace of growth in the food industry, partially because of consumer awareness at a gradual rate. Moreover, sustainable food products are viewed as ineffective in the short run while market share for sustainable items remains substantially low.
  • 494
  • 06 Sep 2022
Topic Review
Gene Therapy in Duchenne Muscular Dystrophy
Gene therapy allows for the modulation and correction of specific problem genes which are mutated in severe pathologies. The term “gene therapy” is loosely defined by many sources. The FDA defines it as “products whose effects are transferred through transcription/translation of genetic material via administration as nucleic acids, viruses, or genetically engineered microorganisms”. Duchenne muscular dystrophy (DMD) is a severe X-linked recessive muscle-wasting disease that results from mutations in the DMD gene on chromosome 21. Due to its poor survivorship, many interventions are being researched to improve outcomes for patients with this disease; gene therapy is an emerging field in this regard.
  • 494
  • 13 Mar 2024
Topic Review
Link between Food Environment and Colorectal Cancer
Food and diet are critical risk factors for colorectal cancer (CRC). Food environments (FEs) can contribute to disease risk, including CRC. CRC incidence was associated with the availability of specific foods such as red meat, meat, animal fats, energy from animal sources, and an unhealthy FE. Increased CRC mortality was linked with the availability of animal fat, red meat, alcoholic beverages, and calorie food availability, residence in food deserts, and lower FE index. There were a variety of associations between CRC and the FE. The availability of specific foods, unhealthy FE, and food desserts impact CRC incidence and mortality.
  • 494
  • 30 Sep 2022
Topic Review
Patient Active Approaches in Osteopathic Practice
Osteopathy is a whole-body patient-centered intervention mainly focused on sustaining a person’s health processes by means of touch-based approaches focused on the somatic dysfunctions (SD) present in different regions of the body. 
  • 493
  • 22 Mar 2022
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