Topic Review
Techno-Stress and Psychological Detachment in Workload and Well-Being
Psychological detachment is a protective factor to cope with excessive job demands. It refers to the ability to psychologically disengage from work when away from the workplace to recover depleted resources. A high workload can hinder psychological detachment, especially in high autonomy and flexibility conditions, forcing workers to remain mentally tied to work.
  • 365
  • 28 Sep 2023
Topic Review
Convalescent Plasma Transfusion for COVID‐19
More than one year into the novel coronavirus disease 2019 (COVID-19) pandemic, healthcare systems across the world continue to be overwhelmed with soaring daily cases. The treatment spectrum primarily includes ventilation support augmented with repurposed drugs and/or convalescent plasma transfusion (CPT) from recovered COVID-19 patients. CPT is a promising COVID-19 therapeutic option that merits internationally coordinated RCTs to achieve a scientific risk-benefit consensus. 
  • 365
  • 24 May 2021
Topic Review
Impact of Premenstrual Syndrome on Quality of Life
Most women who menstruate experience various physical, psychological, and behavioral changes during the period between ovulation and menstruation. 
  • 364
  • 29 Jan 2024
Topic Review
Molecular Determinants of Cancer-Induced Bone Pain
Cancer-related pain is arguably the most common consequences of this disease, significantly reducing quality of life and affecting the ability to complete everyday tasks and live a normal life. Among these, cancer-induced bone pain (CIBP) is one of the most prevalent, presenting as movement-related, constant or most commonly, in combination. Bone metastases can then induce CIBP in several ways, many of which are still under investigation. Indeed, bone is a richly innervated tissue, and sensitive neurons can be found in both the periosteum and the bone marrow.
  • 364
  • 14 Feb 2022
Topic Review
No and Low Alcohol Products
Reducing the alcoholic strength in beverages as a strategy to reduce harmful alcohol use has been proposed by multilateral institutions such as the World Health Organization and governments worldwide. Different industrial and artisanal techniques are used to achieve low-alcohol content beverages. Therefore, regulations regarding the content of alcohol in beverages and strategies to monitor compliance are important, because they are the main reason for classification of the beverages and are central to their categorization and market labelling. Furthermore, analytical techniques with adequate sensitivity as low as 0.04% vol are necessary to determine the alcohol ranges necessary for classification. 
  • 363
  • 29 Sep 2022
Topic Review
Occupational Exposure to Halogenated Anaesthetic Gases in Hospitals
Objective During the induction of gaseous anaesthesia, waste anaesthetic gases (WAGs) can be released into workplace air. Occupational exposure to high levels of halogenated WAGs may lead to adverse health effects; hence, it is important to measure WAGs concentration levels to perform risk assessment and for health protection purposes.
  • 363
  • 13 Mar 2023
Topic Review
Salmonella and Salmonellosis in Public Health Implications
Salmonella is one of the most important zoonotic pathogen agents, causing an estimated 93.8 million cases of gastroenteritis worldwide annually, with 155,000 deaths. Efforts to reduce transmission of Salmonella by food and other routes must be implemented on a global scale. Salmonellosis control strategies are based on two fundamental aspects: (a) the reduction of prevalence levels in animals and (b) protection against infection in humans. 
  • 363
  • 23 Feb 2024
Topic Review
COVID-19 Pandemic on Employee Sleep Quality
COVID-19 was declared a pandemic on 11 March 2020, following a rapid, exponential increase in global cases. The COVID-19 pandemic was associated with depression, anxiety, sleep disturbances, distress, and suicidal ideations. This study explored the association of the COVID-19 pandemic and employee sleep quality at a healthcare technology and services organization.
  • 363
  • 07 Feb 2022
Topic Review
Immunosenescence in Cerebral Small Vessel Disease
Cerebral small vessel disease (CSVD) is one of the most important causes of vascular dementia. Immunosenescence and inflammatory response, with the involvement of the cerebrovascular system, constitute the basis of this disease. Immunosenescence identifies a condition of deterioration of the immune organs and consequent dysregulation of the immune response caused by cellular senescence, which exposes older adults to a greater vulnerability. A low-grade chronic inflammation status also accompanies it without overt infections, an “inflammaging” condition. The correlation between immunosenescence and inflammaging is fundamental in understanding the pathogenesis of age-related CSVD (ArCSVD). The production of inflammatory mediators caused by inflammaging promotes cellular senescence and the decrease of the adaptive immune response. Vice versa, the depletion of the adaptive immune mechanisms favours the stimulation of the innate immune system and the production of inflammatory mediators leading to inflammaging. Furthermore, endothelial dysfunction, chronic inflammation promoted by senescent innate immune cells, oxidative stress and impairment of microglia functions constitute, therefore, the framework within which small vessel disease develops: it is a concatenation of molecular events that promotes the decline of the central nervous system and cognitive functions slowly and progressively.
  • 363
  • 05 Sep 2022
Topic Review
Shortage of General Practitioners
The shortage of general practitioners (GPs) and the fact that country doctors’ practices are vanishing—a situation that is currently taking a turn for the worse in some regions of Germany—are issues that have been dealt with in the media as a topic of specific discussion for some time now.
  • 363
  • 25 Aug 2023
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