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Topic Review
Microbiota in Shaping Women’s Health
A properly colonized human microbiota contributes to the proper functioning of the body. The composition of the natural flora changes depending on age, health, living conditions, and the use of antimicrobial agents: antibiotics, disinfectants, and some cosmetics. The human body is diversely populated with microorganisms and undergoes constant changes under the influence of various factors, and its proper composition is extremely important for the proper functioning of the body.
  • 378
  • 09 Jan 2023
Topic Review
Remotely-Based Pulmonary Rehabilitation
Despite numerous benefits, traditional Pulmonary Rehabilitation (PR) as a resource remains underutilized in chronic lung disease. Less than 3% of eligible candidates for PR attend one or more sessions after hospitalization due to many barriers, including the ongoing COVID-19 pandemic. Emerging alternative models of PR delivery such as home-based PR, tele-rehabilitation, web-based PR, or hybrid models could help address these barriers. Numerous studies have tested the feasibility, safety, and efficacy of these methods, but there is wide variability across studies and methods. We conducted a literature review to help determine if these alternative delivery methods watered down the effectiveness of PR. 
  • 378
  • 13 Dec 2021
Topic Review
Generative AI and Large Language Models for Healthcare
Generative artificial intelligence (AI) and large language models (LLMs), exemplified by ChatGPT, are promising for revolutionizing data and information management in healthcare and medicine.
  • 378
  • 01 Nov 2023
Topic Review
Health Information Systems for Healthcare
Health information system deployment has been driven by the transformation and digitalization confronting healthcare. The need and potential of these systems within healthcare have been tremendously driven by the global instability that has affected several interrelated sectors. Accordingly, many research studies have reported on the inadequacies of these systems within the healthcare arena, which have distorted their potential and offerings to revolutionize healthcare.
  • 377
  • 11 Apr 2023
Topic Review
Mesenchymal Stem Cell-Derived Extracellular Vesicles
Mesenchymal stem cells (MSCs) have recently emerged as promising candidates for treating a variety of age-related conditions, including ageing frailty. MSCs can differentiate into different cell lineages and secrete extracellular vesicles (EVs), such as exosomes and microvesicles, that contain bioactive molecules, such as proteins, nucleic acids, and lipids. These EVs can deliver cargo to target cells and influence cellular processes, such as inflammation, apoptosis, and angiogenesis, promoting tissue repair and regeneration.
  • 379
  • 09 May 2023
Topic Review
Exercise's Effects on Nutritional Status in Cystic Fibrosis
Physical exercise is an important part of regular care for people with cystic fibrosis (CF). Exercise training can produce positive physiologic changes in children with CF without impairing their nutritional status. In fact, resistance exercise can help improve body mass. 
  • 377
  • 15 Apr 2022
Topic Review
Impact of ERK5 on the Hallmarks of Cancer
Extracellular signal-regulated kinase 5 (ERK5) belongs to the mitogen-activated protein kinase (MAPK) family that consists of highly conserved enzymes expressed in all eukaryotic cells and elicits several biological responses, including cell survival, proliferation, migration, and differentiation.
  • 377
  • 14 Jan 2022
Topic Review
Aging and Quality of Life
The aging of the world’s population and the health problems accompanying it are becoming increasingly severe. Healthcare policies in developed countries focus on how to prevent and treat diseases associated with aging and how to maintain quality of life. Typical age-related diseases include deafness, cataracts, osteoarthritis, chronic obstructive pulmonary disease, diabetes mellitus, and dementia. Although the mechanisms by which these diseases develop differ, they are all caused by the accumulation of molecular and cellular damage over time.
  • 377
  • 07 Aug 2023
Topic Review
Complex Interventions in Suicide Research
It has been argued that effective action towards addressing a complex concern such as suicide requires a combination of evidence-based strategies. While these complex public health approaches have recently gained importance, little is known about their characteristics and what contributes to their complexity. 
  • 377
  • 01 Aug 2022
Topic Review
Road Safety Near a Landfill Assessment in Europe
In Europe, many governments are struggling with the ambitious target of zero road deaths by 2050. On the other hand, they are facing remediation of illegal waste dumps, subject to European infringement procedures and involving a lot of workers and heavy materials transportation. In Italy, a specific department was started in 2017 to carry out the remediation of 200 illegal landfills of urban/industrial solid waste. According to the Italian legislative framework on construction site management, risk assessment should also include risks for the external context caused by the working site.
  • 376
  • 26 May 2023
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