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Topic Review
Neighbourhood Socioeconomic Processes and Dynamics and Healthy Ageing
Elderly citizens are concentrated in urban areas and are particularly affected by the immediate residential environment. Cities are unequal and segregated places, where there is an intensification of urban change processes such as gentrification and displacement. Since older adults spend most of their time in their nearby neighbourhood environment due to physical, emotional, and financial reasons, it is essential to understand how the neighbourhood environment affects this population's health. 
  • 456
  • 10 Jun 2022
Topic Review
Adult Inpatients’ Perceptions of Their Fall Risk
Patient falls continue to be a high priority for healthcare organisations due to the detrimental physical, psychological, social and financial consequences that can occur.  A large number of falls in hospitals are unwitnessed and mostly occur due to patient behaviours and not seeking assistance. Understanding these patient behaviours may help to direct fall prevention strategies, with evidence suggesting the need to integrate patients’ perspectives into fall management. The qualitative and quantitative findings are organised into five domains: Fall Risk Perception Measures, Patients’ Perceptions of Fall Risk, Patients’ Perceptions of Falling in Hospital, Patients’ Fear of Falling and Barriers to Fall Prevention in Hospital. 
  • 401
  • 09 Jun 2022
Topic Review
Post-COVID Syndrome and Long-Term Consequences
Post-COVID syndrome or long COVID is defined as the persistence of symptoms after confirmed SARS-CoV-2 infection, the pathogen responsible for coronavirus disease. The content herein presented reviews the reported long-term consequences and aftereffects of COVID-19 infection and the potential strategies to adopt for their management. Recent studies have shown that severe forms of COVID-19 can progress into acute respiratory distress syndrome (ARDS), a predisposing factor of pulmonary fibrosis that can irreversibly compromise respiratory function. Considering that the most serious complications are observed in the airways, the inhalation delivery of drugs directly to the lungs should be preferred, since it allows to lower the dose and systemic side effects. Although further studies are needed to optimize these techniques, recent studies have also shown the importance of in vitro models to recreate the SARS-CoV-2 infection and study its sequelae. The information reported suggests the necessity to develop new inhalation therapies in order to improve the quality of life of patients who suffer from this condition.
  • 827
  • 09 Jun 2022
Topic Review
Azadirachta indica (Neem) as a Potential Natural Active
Azadirachta indica (Neem) is a large tree that is native to India and is traditionally used due to its several properties, mainly to treat skin diseases, as well as its “herbicidal” activity. Its bark, leaves, seeds, fruits and flowers are widely used in medicinal treatment due to the presence of active secondary metabolites with biological effects, mainly limonoids and tetranortriterpenoids, such as azadirachtin. Thus, A. indica was studied in a variety of conditions, such as anticancer, antiseptic, anti-inflammatory and chemopreventive agents, as well as a biopesticide. 
  • 798
  • 09 Jun 2022
Topic Review
Mechanism of CRISPR/Cas Based Detection
In the pace of time, numerous platforms for rapid nucleic acid (NA) detection have been developed; however, they may not be able to satisfy the ASSURED (Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment-free and Deliverable to end-users) parameters set by the World Health of Organization at the same time. Recent studies have established that the CRISPR/Cas system possesses the potential to fulfil ASSURED criteria and demonstrated that it may be repurposed for the detection of contaminants, enzymes, proteins, analytes, and plant diseases, rather than being limited to clinical settings and nucleic acids. Several platforms have yet to be translated into clinical applications and must be brought into clinical settings from the laboratory. 
  • 2.8K
  • 08 Jun 2022
Topic Review
Measures against Toxic of Ochratoxin A
Ochratoxin A (OTA), which is a frequent contaminant in feeds/foods for animals and humans all over the world, is defined by IARC as a possible human carcinogen and belongs to group 2B mycotoxins, which is based on various experimental studies with rats or mice. Therefore, there are still some disputes among the research community in regard to the real potential of OTA to be carcinogenic for animals, poultry or humans because the mentioned above studies address mainly laboratory animals, such as mice or rats, whereas the data for humans, farm animals and poultry are still limited.
  • 395
  • 08 Jun 2022
Topic Review
Mobile Mammography Van in Missouri
Mobile mammography is a tool that has been used to reach underserved women in a diverse number of settings, including urban, rural, and mountain regions. The mobile mammography van, affiliated with Siteman Cancer Center Breast Health Center, acts as part of outreach efforts to increase breast screening rates in medically underserved communities including the St. Louis area (urban) as well as the rural Bootheel region of Missouri. The van reached a particularly vulnerable population that was mostly poor, uninsured, and with limited educational backgrounds regardless of their zip code of service. 
  • 488
  • 07 Jun 2022
Topic Review
Creating Interprofessional Readiness for Complex and Aging Adults
A successful interprofessional faculty development program was transformed into a more clinically focused professional development opportunity for both faculty and clinicians. Discipline-specific geriatric competencies and the Interprofessional Education Collaborative (IPEC) competencies were aligned to the 4Ms framework. The goal of the resulting program, Creating Interprofessional Readiness for Complex and Aging Adults (CIRCAA), was to advance an age-friendly practice using evidence-based strategies to support wellness and improve health outcomes while also addressing the social determinants of health (SDOH). 
  • 431
  • 07 Jun 2022
Topic Review
Thyme
A perennial wild shrub from the Lamiaceae family and native to the Mediterranean region, thyme is considered an important wild edible plant studied for centuries for its unique importance in the food, pharmaceutical, and cosmetic industry. Thyme is loaded with phytonutrients, minerals and vitamins. It is pungent in taste, yet rich in moisture, proteins, crude fiber, minerals and vitamins. Its chemical composition may vary with geographical location but is mainly composed of flavonoids and antioxidants.
  • 1.6K
  • 07 Jun 2022
Topic Review
Canada’s Colonial Genocide of Indigenous Peoples
Indigenous Peoples worldwide, including in Canada and the U.S. have, over generations, experienced assaults on their very survival, along with their culture, land, and ways of life. The Truth and Reconciliation Commission of Canada, established to bring to light the experiences of survivors of the Indian Residential Schools, referred to this program as constituting cultural genocide. While these events all inflicted severe and lasting harm to the survivors, resilience and the perseverance of many aspects of culture may be maintained through intergenerational processes.
  • 346
  • 07 Jun 2022
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