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Topic Review
Biography
Topic Review
Magnetic Fields and Cancer
Humans are exposed to a complex mix of man-made electric and magnetic fields (MFs) at many different frequencies, at home and at work. Epidemiological studies indicate that there is a positive relationship between residential/domestic and occupational exposure to extremely low frequency electromagnetic fields and some types of cancer.
500
10 Feb 2022
Topic Review
Pollen on Adverse Respiratory Outcomes
Respiratory diseases such as asthma, allergic rhinitis (AR) and chronic obstructive pulmonary disease (COPD) affect millions worldwide and pose a significant global public health burden. Over the years, changes in land use and climate have increased pollen quantity, allergenicity and duration of the pollen season, thus increasing its impact on respiratory disease.
500
28 Jun 2022
Topic Review
Circulating Tumor Cells in Colorectal Cancer
Circulating tumor cells (CTCs) are intact cells separated from the primary tumor or metastases and released into the peripheral circulation. They were observed and discovered for the first time in 1869 in the blood of a patient with breast cancer. CTCs mainly originate from solid tumors of epithelial origin (breast, prostate, colon, and lung). CTCs are nucleated and express epithelial cell adhesion molecules (EpCAM) and/or cytokeratins (CK) in the cytoplasm without coexpressing the common leukocyte antigen CD45. It is known today that there is significant heterogeneity in cell species and surface markers, which represents a challenge in isolating all clinically relevant subpopulations of CTCs.
500
22 Nov 2022
Topic Review
Digital Health Interventions by Clinical Pharmacists
Integrating digital interventions in healthcare has gained increasing popularity among clinical pharmacists (CPs) due to advances in technology. Although the impacts of telephone-based interventions on patients’ outcomes were decidedly mixed, web-based interventions and mobile apps exerted generally positive influences.
499
26 Jan 2022
Topic Review
Cognitive Decline following Head and Neck Cancer Radiotherapy
Radiotherapy for head and neck cancers exposes small parts of the brain to radiation, resulting in radiation-induced changes in cerebral tissue. Implementation of neurocognitive assessment with advanced MRI examination in monitoring brain microstructural and functional changes of head and neck cancer patients could detect cognitive changes early. With suitable intervention, further deleterious effects on the patient’s cognition can be prevented.
499
21 Dec 2021
Topic Review
Diagnosis and Prognosis of Food Selectivity in Autism
Autisms Spectrum Disorders (ASD) are characterized by core symptoms (social communication and restricted and repetitive behaviors) and related comorbidities, including sensory anomalies, feeding issues, and challenging behaviors. Children with ASD experience significantly more feeding problems than their peers. In fact, parents and clinicians have to manage daily the burden of various dysfunctional behaviors of children at mealtimes (food refusal, limited variety of food, single food intake, or liquid diet). These dysfunctional behaviors at mealtime depend on different factors that are either medical/sensorial or behavioral.
498
06 Apr 2023
Topic Review
Cultural Safety for LGBTQIA+ People
Although the concept of "cultural safety" as its origins in indigenous nursing care, there is support and rationale for applying this concept for LGBTQIA+ people as a population who experience health disparities due to barriers to access equitable care. Building on Mukerjee and colleagues' 5 "P" tenets (partnerships, personal activities of daily living, prevention of harm, patient centering, and purposeful self-reflection), reviewed studies on components of culturally safe care for LGBTQIA+ people revealed five themes: power-enhancing care; inclusive healthcare institutions; continuous education and research; promotion of visibility; and individualised care.
498
12 Aug 2022
Topic Review
Participatory Action Research for Sexual and Reproductive Health
Youth-friendly sexual and reproductive health (SRH) interventions are essential for the health of adolescents (10–19 years). Co-designing is a participatory approach to research, allowing for collaboration with academic and non-academic stakeholders in intervention development. Participatory action research (PAR) involves stakeholders throughout the planning, action, observation, and reflection stages of research. Current knowledge indicates that co-producing SRH interventions with adolescents increases a feeling of ownership, setting the scene for intervention adoption in implementation settings.
497
10 Mar 2022
Topic Review
Anti-CCR5 Therapy, Breast Cancer and Its Microenvironment
Breast cancer represents the most common malignancy among women in the world. The local microenvironment around the tumor plays a great role in cancer progression and invasion, representing a promising therapeutic target. CCL5 is a potent chemokine with a physiological role of immune cell attraction and has gained particular attention in R&D for breast cancer treatment. Its receptor, CCR5, is a well-known co-factor for HIV entry through the cell membrane and CCR5 blocking represents a mainstay of HIV treatment. Interestingly, CCL5 is currently described as key pro-oncogenic factor, especially in breast cancer. Several studies blocking the CCL5/CCR5 axis show cancer cells become less invasive and less malignant, with less oncogenic extracellular matrices.
497
28 Nov 2022
Topic Review
Parent–Child Interactions in Deafness Children
Despite early identification and advancements in cochlear implant and hearing aid technology, delays in language skills in deaf children continue to exist. Good-quality parent–child interaction (PCI) is a key predictor for the successful development of deaf children’s signed and/or spoken language. As good-quality PCI is widely acknowledged to be significant for child language development in deaf children, then we must have the necessary tools to assess it. This review answers three questions: Which parent behaviours are assessed in PCI? How are they assessed? And which parent interaction behaviours are positively correlated with deaf children's language skills?
497
03 Sep 2021
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