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Topic Review
Anticancer Strategies Targeting JWA
JWA is a microtubule-associated protein and an environmental response gene. JWA has been identified as a potential therapeutic target for several cancers. 
  • 406
  • 08 Oct 2022
Topic Review
Use of Patient-Reported Data within Acute Healthcare Context
 Patient-reported outcome measures (PROMs), patient-reported experience measures (PREMs) and patient satisfaction surveys provide important information on how care can be improved. The Hospital Consumer Assessment of Healthcare Providers and Systems tool (HCAHPS) was used most frequently for measuring patient satisfaction. Where reported, data were applied to improve patient-centred care and utilization of health resources. Gaps in the use of patient data within hospital services are noticeable. Engaging management and improving staff capability are needed to overcome barriers to implementation.
  • 318
  • 30 Sep 2022
Topic Review
Link between Food Environment and Colorectal Cancer
Food and diet are critical risk factors for colorectal cancer (CRC). Food environments (FEs) can contribute to disease risk, including CRC. CRC incidence was associated with the availability of specific foods such as red meat, meat, animal fats, energy from animal sources, and an unhealthy FE. Increased CRC mortality was linked with the availability of animal fat, red meat, alcoholic beverages, and calorie food availability, residence in food deserts, and lower FE index. There were a variety of associations between CRC and the FE. The availability of specific foods, unhealthy FE, and food desserts impact CRC incidence and mortality.
  • 495
  • 30 Sep 2022
Topic Review
Rapid Methods for Early Detection of SARS-CoV-2 Variants
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) straightaway showed its tendency to mutate and adapt to the host, culminating in the emergence of variants; so it immediately became of crucial importance to be able to detect them quickly but also to be able to monitor in depth the changes on the whole genome to early identify the new possibly emerging variants.
  • 323
  • 29 Sep 2022
Topic Review
Trauma-Related Internalizing and Externalizing Behaviors in Adolescence
The adolescent brain is an open window on the environment, which is vulnerable to perturbations and the traumatic experiences occurring before or during this period have an increased saliency in affecting cognitive, emotional, and social levels. During adolescence, trauma-related effects causing significant impairment or suffering could be manifest in internalizing and externalizing behaviors. 
  • 1.5K
  • 29 Sep 2022
Topic Review
No and Low Alcohol Products
Reducing the alcoholic strength in beverages as a strategy to reduce harmful alcohol use has been proposed by multilateral institutions such as the World Health Organization and governments worldwide. Different industrial and artisanal techniques are used to achieve low-alcohol content beverages. Therefore, regulations regarding the content of alcohol in beverages and strategies to monitor compliance are important, because they are the main reason for classification of the beverages and are central to their categorization and market labelling. Furthermore, analytical techniques with adequate sensitivity as low as 0.04% vol are necessary to determine the alcohol ranges necessary for classification. 
  • 359
  • 29 Sep 2022
Topic Review
The New Global Health Emergency: Monkeypox
Monkeypox, once a rare zoonotic disease, has been endemic to some African countries since its original identification among humans in 1970. Since then, cases in non-endemic regions have been linked to returning travelers or those who had contact with transported animals. The causative agent, Monkeypox virus, belongs to Orthopoxviruses, the same family as Variola—the causative organism for smallpox. Although most monkeypox outbreaks until recently were linked to zoonotic transmission, secondary human–human transmission in smallpox-unvaccinated individuals was observed in a small proportion of overall cases. Smallpox was declared to be eradicated in 1980, and since its eradication, Monkeypox virus has been the most significant poxvirus to cause human disease. The 2022 monkeypox outbreak marks a significant paradigm shift in the human and poxvirus association, with new modes of transmission and concerns of viral evolution and entrenchment as a sexually transmitted disease. Monkeypox clinically resembles smallpox but is far milder. At this time, there are no approved therapies for monkeypox, and antiviral agents effective against smallpox are being utilized. Additionally, preventive strategies being utilized include smallpox vaccinations such as JYNNEOS and ACAM2000.
  • 328
  • 28 Sep 2022
Topic Review
Recreational Nitrous Oxide Use
Nitrous oxide (N2O) is a dissociative anaesthetic that is sometimes used recreationally. The prevalence of N2O use is difficult to quantify but appears to be increasing. Research on N2O harms and application of harm reduction strategies are limited. The disparate body of research on recreational nitrous oxide use to inform harm reduction approaches tailored for young people was collated and synthesised. 
  • 379
  • 28 Sep 2022
Topic Review
Attachment and Health
Attachment and Health is psychological model which considers how attachment theory pertains to people’s preferences and expectations for the proximity of others when faced with stress, threat, danger or pain. In 1982 the American Psychiatrist, Lawrence Kolb, noticed that patients with chronic pain displayed behaviours with their healthcare providers akin to what children might display with an attachment figure, thus marking one of the first applications of attachment theory to physical health. Development of adult attachment theory and adult attachment measures in the 1990s provided researchers with the means to apply attachment theory to health in a more systematic way. Since that time it has been used to understand variation in stress response, health outcomes and health behaviour. Ultimately, the application of attachment theory to health care may enable health care practitioners to provide more personalized medicine by creating a deeper understanding of patient distress and allowing clinicians to better meet their needs and expectations.
  • 491
  • 27 Sep 2022
Topic Review
Risk Perception of Air Pollution
The adverse health effects of exposure to air pollutants, notably to particulate matter (PM), are well-known, as well as the association with measured or estimated concentration levels. The role of perception can be relevant in exploring effects and pollution control actions.
  • 436
  • 27 Sep 2022
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