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Topic Review
Diagnostically Challenging Subtypes of Invasive Lobular Carcinomas
Invasive lobular carcinoma is the most common special breast carcinoma subtype, with unique morphological (discohesive cells, single-cell files, targetoid pattern) and immunohistochemical (loss of E-cadherin and β-catenin staining) features. Moreover, ILC displays a poor response to neoadjuvant therapy, a different metastatic pattern compared to invasive breast carcinoma of no special type, as well as unique molecular characteristics. In addition to the classic variant of invasive lobular carcinoma, several other well-recognized variants exist, including classic, alveolar, tubulolobular, solid, pleomorphic, signet-ring, and mixed. 
  • 185
  • 10 Oct 2023
Topic Review
Augmented Reality in Neurosurgery
Augmented reality (AR) involves the overlay of computer-generated images onto the user’s real-world visual field to modify or enhance the user’s visual experience. With respect to neurosurgery, AR integrates preoperative and intraoperative imaging data to create an enriched surgical experience that has been shown to improve surgical planning, refine neuronavigation, and reduce operation time. In addition, AR has the potential to serve as a valuable training tool for neurosurgeons in a way that minimizes patient risk while facilitating comprehensive training opportunities.
  • 271
  • 09 Oct 2023
Topic Review
Qualitative Methods in Translational Health
Translational health research is an interdisciplinary field aimed at bridging the gap between basic science studies, preventative studies, and clinical practice to improve health-related outcomes. Qualitative research methods provide a unique perspective on the emotional, social, cultural, and contextual factors that influence health and healthcare and thus are recognized as valuable tools for translational health research. This approach can be embedded within a mixed method design which complements the quantitative findings.
  • 346
  • 09 Oct 2023
Topic Review
Investigating and Quantifying Food Insecurity in Nigeria
Given the recent increase in the number of Nigerians estimated to be at risk of food insecurity, it is crucial to explore the array of tools used to quantify food insecurity (FI). This exploration will help determine the prevalence and severity of FI in Nigeria. 
  • 696
  • 09 Oct 2023
Topic Review
Cervical Cancer Detection
Cervical cancer is a common and preventable disease that poses a significant threat to women’s health and well-being. It is the fourth most prevalent cancer among women worldwide, with approximately 604,000 new cases and 342,000 deaths in 2020, according to the World Health Organization. 
  • 142
  • 08 Oct 2023
Topic Review
Factors Associated with Dietary Patterns of Schoolchildren
The children’s dietary patterns were related to their behavior, nutritional status, and family environment habits. Food and nutrition education’s effective actions, as well as the regularization of the marketing of ultra-processed foods, must be stimulated and inserted in public policies as a way to promote and protect children’s health.
  • 174
  • 07 Oct 2023
Topic Review
Techno-Stress and Psychological Detachment in Workload and Well-Being
Psychological detachment is a protective factor to cope with excessive job demands. It refers to the ability to psychologically disengage from work when away from the workplace to recover depleted resources. A high workload can hinder psychological detachment, especially in high autonomy and flexibility conditions, forcing workers to remain mentally tied to work.
  • 352
  • 28 Sep 2023
Topic Review
Neurogenic Bone Loss after Spinal Cord Injury
Osteoporosis is a common skeletal disorder which can severely limit one’s ability to complete daily tasks due to the increased risk of bone fractures, reducing quality of life. Spinal cord injury (SCI) can also result in osteoporosis and sarcopenia.
  • 116
  • 28 Sep 2023
Topic Review
Physiotherapy in Human T-Lymphotropic Virus 1 Infection
The human T-lymphotropic virus 1 (HTLV-1) is a retrovirus in the Retroviridae family that affects human blood T lymphocytes and can cause neurological disorders. This infection is characterized by silent, long-term persistence in the host. Physical therapy has been prescribed for neurological complications associated with HTLV-1 because it improves functional status, reduces symptoms, and positively impacts patients’ quality of life
  • 254
  • 28 Sep 2023
Topic Review
Corporate Climate Change Impacts and Due Diligence
Climate change has been described as one of the greatest threats to people and the planet. Its impacts affect virtually the entire spectrum of internationally recognised human rights as well as the environment in and of itself. In relation to human rights, there is a growing consensus that companies should exercise human rights due diligence in order to identify and prevent their actual and potential adverse impacts.
  • 394
  • 27 Sep 2023
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