Topic Review
Lignin-Based Sunscreens
In light of recent research, a vast majority of the commonly-used broad-range sunscreens fail to provide adequate protection against portions of sunlight that age and otherwise damage the skin, including visual light. In addition, many of their UV-active synthetic components that easily pass through effluent wastewater treatment plants have been linked to coral bleaching and other negative effects on marine ecosystems. These compounds may also penetrate the skin and are suspected of causing allergies and acting as hormone disruptors. Technical lignins are phenolic biopolymers obtained in large quantities as by-products of chemical pulping and biomass refinery processes that have been found to be of low toxicity to normal mammalian cells. Because of their polymeric nature, they should be much easier to remove from wastewater than the small synthetic UV-active compounds used in chemical sunscreens. Provided that they have the right chemical structure and are converted to nanoparticles, they display significant absorbance in the UV- and visual wavelength areas of sunlight. Most commercial sunscreens are whitish because of perceived consumer preference and for this reason, contain only compounds that have insignificant absorbance in the visual region of sunlight. Coupled with their ability to act as antioxidants and preservatives, lignin-based sunscreens offer themselves as a bio-based and safe multi-functional additive for high-SPF (Sun Protection Factor) sunscreens and cosmetics. This review addresses the state-of-the art of lignin-based sunscreens.
  • 1.1K
  • 19 Nov 2020
Topic Review
Gender, Inequality and Commercial Determinants
Scholarship on the commercial determinants of health (CDoH) has sought to understand the multiple ways corporate policies, practices and products affect population health. At the same time, gender is recognised as a key determinant of health and an important axis of health inequalities. To date, there has been limited attention paid to the ways in which the CDoH engage with and impact on gender inequalities and health.
  • 693
  • 18 Nov 2020
Topic Review
Pharmaceutical Service
Pharmaceutical services are activities of pharmacists in the healthcare system to obtain a measurable benefit, including providing access to high-quality medicinal products, subsequent rational management, as well as preventive medicine.
  • 705
  • 12 Nov 2020
Topic Review
Transarterial Chemoembolization
TACE is widely performed for inoperable HCCs; however, its therapeutic effects on HCC is strongly influenced by techniques. Therefore, it is important to properly use the TACE techniques according to the patient and tumor condition. Among them, cTACE is a skill to cure localized HCCs; however, it should be performed as selectively as possible because it also damages the normal liver.
  • 1.1K
  • 12 Nov 2020
Topic Review
Human Thermoregulation
The international community has recognized global warming as an impending catastrophe that poses significant threat to life on earth. In response, the signatories of the Paris Agreement (2015) have committed to limit the increase in global mean temperature to < 1.5 oC, from pre-industry period, which is defined as 1850 - 1890. Considering that the protection of human life is a central focus in the Paris Agreement, the naturally endowed properties of the human body to protect itself from environmental extremes should form the core of an integrated and multifaceted solution against global warming. Scholars believe that heat and thermoregulation play important roles in the evolution of life and continue to be a central mechanism that allow humans to explore, labor and live in extreme conditions. However, the international effort against global warming has focused primarily on protecting the environment and on the reduction of greenhouse gases by changing human behavior, industrial practices, and government policies, with limited consideration given to the nature and design of the human thermoregulatory system. Global warming is projected to challenge the limits of human thermoregulation, which can be enhanced by complementing innate human thermo-plasticity with the appropriate behavioral changes and technological innovations. Therefore, the fundamental concepts and physiology of human thermoregulation should form the underlying bases for human adaptation to global warming and for designing behavioral adaptations and technological innovations to enhance human capacity to function in a warmer environment. A potential behavioral adaptation to global warming is that sleep-wake cycle would gravitate towards a sub-nocturnal pattern, especially for outdoor activities, to avoid the heat of the day. Technologically, the current concept of cooling the space in the room, would likely steer towards targeted body surface cooling. Solar energy is likely to overtake fossil fuel-based energy as the main source of electrical supply globally and more manual labor tasks would need to be replaced by machines and robots to reduce metabolic heat production. There should be more integrated solutions between biologists, behavioral scientists, and technologists, so that man and machine can enhance each other to bring about better solutions against the threat of global warming. 
  • 1.0K
  • 09 Nov 2020
Topic Review
Decision Support for Patient-Centered Care
Care management strategies could be effectively used and augmented by shared decision support systems or artificial intelligence.  Evidence-based approaches to the determinants and consequences of chronic care management  are suggested. The proper utilization of care management strategies will not only enhance better patient care outcomes but also reduce the hospitalization or readmission.
  • 1.0K
  • 02 Nov 2020
Topic Review
Non-alcoholic Fraction of Beer
The present review focuses on the effects of non-alcoholic components of beer on abdominal fat, osteoporosis and body hydration in women, conditions selected for their relevance to health and aging. Although beer drinking is commonly believed to cause abdominal fat deposition, the available literature indicates this outcome is inconsistent in women. Additionally, the non-alcoholic beer fraction might improve bone health in postmenopausal women, and the effects of beer on body hydration, although still unconfirmed seem promising. Most of the health benefits of beer are due to its bioactive compounds, mainly polyphenols, which are the most studied. As alcohol-free beer also contains these compounds, it may well offer a healthy alternative to beer consumers.
  • 1.9K
  • 01 Nov 2020
Topic Review
Detection and Diagnosis of SARS-CoV-2/COVID-19
Latest weeks the humanity is faced with the spread of a new coronavirus, SARS-CoV-2 that causes a respiratory illness with high mortality rates, COVID-19. Since there is no approved treatment or vaccination against that specific coronavirus the reduce in virus spread is essential. That is based in the use of appropriate tools, enabling the accurate and early detection. Molecular biology and immunological techniques are widely used in order to predict the COVID-19 cases in a very short period of time. These are commonly based either in identification of the SARS-CoV-2’s genetic material or in detection of antibodies that have been produced by the immune system against the virus. Many of the above mentioned tests have been validated and approved by local authorities. However, there are much more companies that provide detection tests, without basic validation processes, contributing in non-precise data. The present review aim to analyze the most common platforms that are used in COVID-19 detection, analyzing their advantages and weaknesses. Therefore, each physician will be equipped with appropriate information required for each test.
  • 2.8K
  • 29 Oct 2020
Topic Review
Whey Proteins
Whey proteins have implications in different fields related to human life quality. The aim of this overview was to present the basic chemistry of β-lactoglobulin, α-lactalbumin, and lactotransferrin - main proteins of bovine whey. 
  • 1.8K
  • 27 Oct 2020
Topic Review
Nutrition-focused QIPs in Cancer Care
Malnutrition in patients with cancer is a ubiquitous but neglected problem that can reduce patient survival/quality of life and increase treatment interruptions, readmission rates, and healthcare costs. Malnutrition interventions, including nutrition support through dietary counseling, diet fortification, oral nutrition supplements (ONS), and enteral and parenteral nutrition can help improve health outcomes. However, nutritional care standards and interventions for cancer are ambiguous and inconsistently applied. The lack of systematic malnutrition screening and intervention in ambulatory cancer care has especially significant consequences and thus the nutrition support of patients with cancer represents an area for quality improvement. United States healthcare payment models such as the Oncology Care Model are linked to quality of care and health outcomes. Quality improvement programs (QIPs) can advance patient-centered care, perfect care processes, and help healthcare professionals meet their quality measure performance goals. Malnutrition QIPs like the Malnutrition Quality Improvement Initiative (MQii) have been shown to be effective in identifying and treating malnutrition. However, little is known about or has been reported on nutrition or malnutrition-focused QIPs in cancer care. This paper provides information to support translational research on quality improvement and outlines the gaps and potential opportunities for QIPs in the nutrition support of patients with cancer.
  • 965
  • 27 Oct 2020
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