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Topic Review
Salivary XIST expression and OSCC
Studies have shown that there is a disparity between males and females in south-east Asia with regard to oral cancer morbidity. XIST may play an important role in oral cancer morbidity when associated with sex. Lack of salivary lncRNA XIST expression was associated with an increased risk of oral squamous cell carcinoma (OSCC). 
  • 406
  • 29 Oct 2021
Topic Review
Honey and Atherosclerosis
Honey, a natural sweetener has been used universally as a complete food and in complementary medicine since early antiquity. Honey contains over 180 substances, including sugars mainly fructose and glucose, water and a plethora of minor constituents such as vitamins, minerals and phytochemicals.  Atherosclerosis is a chronic disease occurring in the inner lining of arterial walls due to the progressive plaque formation. Multiple risk factors are implicated in the pathogenesis of atherosclerosis, including oxidative stress, inflammatory responses, hypercholesterolemia, hypertension, diabetes and cigarette smoking.
  • 3.4K
  • 29 Oct 2021
Topic Review
Smoking a Dangerous Addiction
Despite growing knowledge of the adverse effects of cigarette smoking on general health, smoking is one of the most widely prevalent addictions around the world. Globally, about 1.1 billion smokers and over 8 million people die each year because of cigarette smoking. Smoking acts as a source for a variety of oral and systemic diseases. Various periodontal issues such as increased pocket depth, loss of alveolar bone, tooth mobility, oral lesions, ulcerations, halitosis, and stained teeth are more common among smokers. This systematic review was conducted according to the guidelines from PRISMA, and research articles were retrieved from the Web database sources on 31 May 2021. The quality of research articles was ensured by the type of evidence from combined schema incorporating as schema-13 evidence type description, Cochrane health promotion and public health field (CHPPHF), and the health gains notation framework-14 screening question for quality assessment of qualitative and quantitative studies. Smokers have been found to have bleeding on probing, periodontal pockets, and clinical attachment loss compared to nonsmokers. Oral and respiratory cancers are among the most lethal known diseases caused by cigarette smoking and other commonly occurring sequelae such as stained teeth, periodontal diseases, etc. 
  • 291
  • 29 Oct 2021
Topic Review
Apps for Coronary Heart Disease
Mobile health applications (MHA) are discussed to contribute in overcoming this gap in treatment by fostering CHD management. First, MHA may support daily monitoring of activities and symptoms. Second, adherence to treatment and lifestyle changes can be increased by self-tracking, feedback, and reminder functions of MHA.
  • 590
  • 28 Oct 2021
Topic Review
Influence of War and Conflict on Infectious Disease
Infectious diseases as the main reason or as a complication to surgical procedures were the main causes of deaths among soldiers during the Swedish–Russian war in the late 1780s. While the toll on civilians of infectious disease resulting from conflict is harder to measure, there is no doubt that it is far greater still. For these reasons, infectious diseases have been referred to as the “third army” during an armed conflict.
  • 890
  • 28 Oct 2021
Topic Review
Income Inequality and Race/Ethnicity Drive Obesity
Obesity is a major public health problem both globally and within the U.S. It varies by multiple factors, including but not limited to income and sex. After controlling for potential covariates, there is little evidence to determine the association between income and obesity and how obesity may be moderated by sex and family income. We examined the association between income and obesity in U.S. adults aged 20 years and older, and tested whether this relationship differs by race or ethnicity groups. For this analysis, we used data from the 1999–2016 National Health and Nutrition Examination Surveys (NHANES). Obesity was determined using Body Mass Index ≥ 30 kg/m2; the Gini coefficient (GC) was calculated to measure income inequality using the Poverty Income Ratio (PIR). We categorized the PIR into five quintiles to examine the relationship between income inequality and obesity. For the first set of analyses, we used a modified Poisson regression in a sample of 36,665 adults, with an almost equal number of men and women (women’s ratio was 50.6%), including 17,303 white non-Hispanics (WNH), 7475 black non-Hispanics (BNHs), and 6281 Mexican Americans. The models included age, racial/ethnic groups, marital status, education, health behaviors (smoking and drinking status and physical activities), health insurance coverage, self-reported health, and household structure (live alone and size of household). Adjusting for potential confounders, our findings showed that the association between PIR and obesity was positive and significant more frequently among WNH and BNH in middle and top PIR quintiles than among lower-PIR quintiles; this association was not significant in Mexican Americans (MAs). Results of GC in obese women showed that in comparison with WNHs (GC: 0.34, S.E.: 0.002), BNHs (GC: 0.38, S.E.: 0.004) and MAs (GC: 0.41, S.E.: 0.006) experienced higher income inequality, and that BNH obese men experienced the highest income inequality (GC: 0.45, S.E.: 0.011). The association between PIR and obesity was significant among WNHs and BNHs men in the 3rd, 4th and 5th PIR quintiles. The same association was not found for women. In treating obesity, policymakers should consider not only race/ethnicity and sex, but also strategies to reduce inequality in income. 
  • 474
  • 28 Oct 2021
Topic Review
Diet Quality Index and Obesity among Chinese Adults
Obesity, or excess adiposity, is a leading public health problem worldwide that results in significant medical burdens. Diet quality scores designed based on Western-style dietary patterns were demonstrated to be good indicators of obesity in developed but not developing countries. This entry shows that diet quality scores tailored to the Chinese diet demonstrate a strong relationship with both undernutrition and overnutrition, as well as being underweight and obese in Chinese adults. 
  • 375
  • 28 Oct 2021
Topic Review
Digital Health Intervention Engagement
There has been a proliferation of digital health interventions (DHIs) targeting dietary intake. Despite their potential, the effectiveness of DHIs are thought to be dependent, in part, on user engagement. However, the relationship between engagement and the effectiveness of dietary DHIs is not well understood.
  • 522
  • 27 Oct 2021
Topic Review
Safety Training
The purpose of safety training in acquiring knowledge about safety at work is to obtain information about the hazards present in the workplace and the necessary measures worn or kept by employees to protect him/her from one or more hazards associated with the presence of dangerous or harmful factors in the work environment (types of PPE). 
  • 736
  • 27 Oct 2021
Topic Review
Retinoic Acid and Retinaldehyde Dehydrogenase
Retinoic acid (RA) is an important biological metabolite synthesized from the retinol content (known as “vitamin A”) via a sequential cellular process in the retinoid signaling pathway (RSP). RSP-mediated RA biosynthesis is a vital physiological process in chordates, since RA interacts with the nuclear receptor superfamily, namely nuclear RA receptors (RARs) and retinoid X receptors (RXRs), bound to the RA response elements (RAREs) in the promoter region of RA target genes. Retinaldehyde dehydrogenases (RALDH) belongs to the oxidoreductase family and plays a critical role in RA synthesis from the retinaldehyde content; therefore, this enzyme is considered to be one of the key regulators of RA-related retinol metabolism and embryonic development.
  • 613
  • 27 Oct 2021
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