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All Topic Review Biography
Topic Review
Mirror Neuron System to Treat Gait
Gait is affected from the early stages of the disease and its worsening runs parallel to the progression of the pathology where three phases could be established. Treatment of gait are focused on medication, brain surgery, and physiotherapy. The more used medication is levodopa, and regarding brain surgery, deep brain stimulation (DBS) in the subthalamic nuclei is the most used option. Both treatments lead to an improvement in spatiotemporal parameters of gait and freezing of gait (FOG), obtaining good results from the beginning up to two years after the intervention, but becoming less evident with the progression of parkinson's disease.
  • 432
  • 12 Aug 2022
Topic Review
Geriatric Care Management System Powered by the IoT
The digitalisation of geriatric care refers to the use of emerging technologies to manage and provide person-centered care to the elderly by collecting patients’ data electronically and using them to streamline the care process, which improves the overall quality, accuracy, and efficiency of healthcare. In many countries, healthcare providers still rely on the manual measurement of bioparameters, inconsistent monitoring, and paper-based care plans to manage and deliver care to elderly patients. This can lead to a number of problems, including incomplete and inaccurate record-keeping, errors, and delays in identifying and resolving health problems. 
  • 432
  • 20 Jul 2023
Topic Review
Urine HPV Testing
Urine HPV detection has the potential to become a most promising tool that could expand the possibilities in changing genital and cervical cancer prevention strategies as well as in the surveillance and management of genital precancer.
  • 432
  • 21 Apr 2021
Topic Review
Unawareness of Chronic Kidney Disease in Germany
Chronic kidney disease (CKD) is associated with an increased risk for cardiovascular events, hospitalizations, end stage renal disease and mortality. Main risk factors for CKD are diabetes, hypertension, and older age. Although CKD prevalence is about 10%, awareness for CKD is generally low in patients and physicians, hindering early diagnosis and treatment. We analyzed baseline data of 3305 participants with CKD Stages 1–4 from German cohorts and registries collected in 2010. Prevalence of CKD unawareness and prevalence ratios (PR) (each with 95%-confidence intervals) were estimated in categories of age, sex, CKD stages, BMI, hypertension, diabetes and other relevant comorbidities. We used a log-binomial regression model to estimate the PR for CKD unawareness for females compared to males adjusting for CKD stage and CKD risk factors. CKD unawareness was high, reaching 71% (68–73%) in CKD 3a, 49% (45–54%) in CKD 3b and still 30% (24–36%) in CKD4. Prevalence of hypertension, diabetes or cardiovascular comorbidities was not associated with lower CKD unawareness. Independent of CKD stage and other risk factors unawareness was higher in female patients (PR = 1.06 (1.01; 1.10)). Even in patients with CKD related comorbidities, CKD unawareness was high. Female sex was strongly associated with CKD unawareness. Guideline oriented treatment of patients at higher risk for CKD could increase CKD awareness. Patient–physician communication about CKD might be amendable. 
  • 432
  • 18 Nov 2021
Topic Review
Mental Stress in Medical Students during the Pandemic
Because of the COVID-19 pandemic, students had to interrupt their regular studies, and universities changed their teaching formats. The lockdowns affected students in more ways than simply their teaching formats. Students require individual support to adjust to difficult situations, and particularly medical students in their preclinical phase compared to students in their clinical phases. These are challenges for the medical education system, which must find ways to be prepared for future times of crisis and insecurity.
  • 431
  • 23 Sep 2022
Topic Review
Rehabilitation of Gait and Balance in Cerebral Palsy
Cerebral palsy (CP) is a congenital and permanent neurological disorder due to non-progressive brain damage that affects gross motor functions, such as balance, trunk control and gait. CP gross motor impairments yield more challenging right foot placement during gait phases, as well as the correct direction of the whole-body center of mass with a stability reduction and an increase in falling and tripping. For these reasons, robotic devices, thanks to their biomechanical features, can adapt easily to CP children, allowing better motor recovery and enjoyment. In fact, physiotherapists should consider each pathological gait feature to provide the patient with the best possible rehabilitation strategy and reduce extra energy efforts and the risk of falling in children affected by CP.
  • 431
  • 10 May 2023
Topic Review
Crowd Management during COVID-19 with Artificial Intelligence
COVID-19 requires crowded events to enforce restrictions, aimed to contain the spread of the virus. However, we have seen numerous events not observing these restrictions, thus becoming super spreader events. In order to contain the spread of a human to human communicable disease, a number of restrictions, including wearing face masks, maintaining social distancing, and adhering to regular cleaning and sanitization, are critical. These restrictions are absolutely essential for crowded events. Some crowded events can take place spontaneously, such as a political rally or a protest march or a funeral procession. Controlling spontaneous crowded events, like a protest march, political rally, celebration after a sporting event, or concert, can be quite difficult, especially during a crisis like the COVID-19 pandemic.
  • 431
  • 14 Jan 2022
Topic Review
ERK5 Expression and Function in Cancer
Extracellular signal-regulated kinase 5 (ERK5) is a unique kinase among MAPKs family members, given its large structure characterized by the presence of a unique C-terminal domain. Despite increasing data demonstrating the relevance of the ERK5 pathway in the growth, survival, and differentiation of normal cells, ERK5 has recently attracted the attention of several research groups given its relevance in inflammatory disorders and cancer.
  • 431
  • 20 Jan 2022
Topic Review
Lower Cardiovascular Disease Risk in Midlife Black Women
Midlife Black women suffer disproportionately from cardiovascular disease (CVD) and stroke in comparison to White women of similar age and demographic. Risks factors  for CVD and stroke are largely considered to be modifiable yet, CVD prevention and awareness campaigns have been less effective among Black women. Decreased awareness of personal CVD risk is associated with delays in the presentation of women to the emergency room or health care providers for symptoms of myocardial infarction. The Midlife Black Women’s Stress and Wellness (B-SWELL) program was co-designed with the community to increase awareness about CVD risk factors, stress, and healthy lifestyle behaviors among midlife Black women.
  • 431
  • 14 Feb 2022
Topic Review
Neuropsychiatric Complications of SARS-CoV-2 Infection
Beginning with the various strategies of the SARS-CoV-2 virus to invade the bodies and manifest infection, and ending with the long COVID, people are witnessing the evolving course of the disease in addition to the pandemic. Given the partially controlled course of the COVID-19 pandemic, the greatest challenge lies in managing the short- and long-term complications of COVID-19.
  • 431
  • 20 Dec 2022
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