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Topic Review
Biography
Topic Review
COVID-19 Diseases in Lipid Metabolism Pregnancy Women
Coronavirus disease (COVID-19) is an infectious disease caused by SARS-CoV-2. Elderly people, people with immunodeficiency, autoimmune and malignant diseases, as well as people with chronic diseases have a higher risk of developing more severe forms of the disease. Pregnant women and children can becomesick, although more often they are only the carriers of the virus. Studies have indicated that infants can also be infected by SARS-CoV-2 and develop a severe form of the disease with a fatal outcome. Acute Respiratory Distress Syndrome (ARDS) ina pregnant woman can affect the supply of oxygen to the fetus and initiate the mechanism of metabolic disorders of the fetus and newborn caused by asphyxia. The initial metabolic response of the newborn to the lack of oxygen in the tissues is the activation of anaerobic glycolysis in the tissues and an increase in the concentration of lactate and ketones. Lipid peroxidation, especially in nerve cells, is catalyzed by iron released from hemoglobin, transferrin and ferritin, whose release is induced by tissue acidosis and free oxygen radicals. Ferroptosis-inducing factors can directly or indirectly affect glutathione peroxidase through various pathways, resulting in a decrease in the antioxidant capacity and accumulation of lipid reactive oxygen species (ROS) in the cells, ultimately leading to oxidative cell stress, and finally, death.
458
15 Dec 2022
Topic Review
Recessive Achromatopsia in Original Braunvieh Cattle
Sporadic occurrence of inherited eye disorders has been reported in cattle but so far pathogenic variants were found only for rare forms of cataract but not for retinopathies.
458
03 Dec 2021
Topic Review
Antibiotic-Resistant Staphylococcus spp.
The application of antibiotics to orange trees in open production environments to halt the spread of bacterial disease presents risks to the environment and creates health concerns for Thai farmers using those agents. ARB on crops such as oranges may enter the global food supply and adversely affect public health.
458
10 Jan 2022
Topic Review
Diet in Asthma
Asthma is a chronic respiratory disease that impacts millions of people worldwide. Several dietary factors have been recognized as potential contributors to the development and severity of asthma for its inflammatory and oxidative effects. Some food groups such as fruits and vegetables, whole grains, and healthy fats appear to exert positive effects on asthma disease. On the other hand, a high consumption of dietary salt, saturated fats, and trans-fat seems to have the opposite effect.
458
02 Jun 2023
Topic Review
Contraceptive Use in the United States
Contraceptive use is deemed one of the 10 greatest public health achievements of the 20th century because its benefits are universally acknowledged as a cornerstone for reducing global maternal morbidity and mortality. Current data indicates gaps in contraceptive use patterns in the US, particularly among low-income women and those from racial/ethnic and gender minority subgroups, necessitating further investigation using an ecological approach.
457
25 Nov 2021
Topic Review
VISTA, PDL-L1, and BRAF—Markers in Prognosis of Melanoma
Melanoma is currently known as one of the most aggressive malignant tumors. T cell Activation (VISTA) is a novel target that is considered to be highly important in determining the invasive potential and treatment response of a melanoma. Programmed death-ligand 1 (PD-L1) is a marker with whose importance has been revealed in multiple types of malignancies.
457
29 Mar 2022
Topic Review
Obstructive Sleep Apnea in Heart Failure
Obstructive sleep apnea (OSA) is characterized by repetitive upper airway closure due to soft tissue collapse and genioglossus muscle relaxation in the upper airway resulting in apneas (cessation of breathing for 10 s or longer) and hypopneas (reductions in breathing coupled with desaturation and/or arousal). OSA is highly prevalent among patients with asymptomatic left ventricular systolic and diastolic dysfunction and congestive heart failure, and if untreated may contribute to the clinical progression of heart failure (HF).
457
06 Jul 2022
Topic Review
Dietary Fibre and Colorectal Adenoma
Colorectal cancer is the third most common cancer among men (after lung and prostate cancer) and the second among women (after breast cancer) worldwide, with approximately 2 new million cases (among both men and women) in 2020. Colorectal cancer is one of the few cancers for which a population screening program is in place practically all over the world. Fibre might play a protective role through several mechanisms, including physical mechanisms, anti-inflammatory properties and prebiotic effects. Results from two extensive and recent meta-analyses confirm the protective role of fibre on colon and rectal cancer risk
456
27 Apr 2021
Topic Review
Linear Motor Driven Leg-Press Dynamometer
Regarding the acute responses after leg-press strength training with or without serial stretch-loading stimuli, visible changes were observed in the muscle force, rate of force development, and hormonal concentrations between pre- and postmenopausal women (only one study). Long-term studies revealed different training adaptations after performing leg-press strength training with unique serial stretch-loading stimuli. A positive trend for leg-press strength training with serial stretch-loading was recorded in the young population and athletes; however, more variable training effects favoring one or the other approach were achieved in the older population.
456
26 Apr 2022
Topic Review
Attitudes toward Female Genital Mutilation/Circumcision
Understanding the attitudes toward FGM/C held by people who have been involved in this practice can lead to more active interventions to prevent this harmful practice. Circumcised women can play a key role in encouraging the abandonment of FGM/C through educational and cultural campaigns.
456
23 Sep 2021
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