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Topic Review
Advances in Curcumin Formulations
Traditional clinical procedures for treating or removing tumors, such as chemotherapy, radiotherapy, and surgical dissection, are widely used. Although chemotherapy remains a very efficient strategy in the battle against cancer, it is typically associated with substantial drawbacks and side effects. Therefore, there remains the possibility that tumors that have been surgically removed may return and may also be resistant to radiation treatment. Marine and terrestrial natural products are far more favorable for improving treatment outcomes in disorders with complicated pathological behavior. Due to their biochemical structures, natural compounds can affect numerous cellular targets, such as genes and proteins. Herbal preparations and their related natural products offer a pivotal role in cancer chemotherapy and chemoprevention. As they are safe and able to minimize the side effects on healthy cells, selected medicinal plants have been developed to address a variety of malignancies. Curcumin is a polyphenol derivative found in the turmeric plant (Curcuma longa L.), and provides chemopreventive, antitumor, chemo-, and radio-sensitizing properties. 
  • 622
  • 08 Oct 2022
Topic Review
Advances in Translational Nanotechnology
       The burgeoning field of nanotechnology aims to create and deploy nanoscale structures, devices, and systems with novel, size-dependent properties and functions. The nanotechnology revolution has sparked radically new technologies and strategies across all scientific disciplines, with nanotechnology now applied to virtually every area of research and development in the US and globally. NanoFlorida was founded to create a forum for scientific exchange, promote networking among nanoscientists, encourage collaborative research efforts across institutions, forge strong industry-academia partnerships in nanoscience, and showcase the contributions of students and trainees in nanotechnology fields. The 2019 NanoFlorida International Conference expanded this vision to emphasize national and international participation, with a focus on advances made in translating nanotechnology. This review highlights notable research in the areas of engineering especially in optics, photonics and plasmonics and electronics; biomedical devices, nano-biotechnology, nanotherapeutics including both experimental nanotherapies and nanovaccines; nano-diagnostics and -theranostics; nano-enabled drug discovery platforms; tissue engineering, bioprinting, and environmental nanotechnology, as well as challenges and directions for future research.
  • 758
  • 30 Oct 2020
Topic Review
Advantages of 2D Materials and Cellulose in Biosensors
The use of 2D materials in biosensor applications provides several advantages, including excellent mechanical, optical, and electrical properties. These properties are essential for the development of wearable biosensors that enable real-time monitoring of human health information and accurate measurement of vital signs. Integrating 2D materials into wearable biosensors has expanded opportunities for early detection of life-threatening diseases and continuous health tracking. In addition to 2D materials, cellulose-based biosensors also offer significant benefits. They are cost-effective, highly sensitive, and compatible with portable sensing devices used in biomedical applications. One major advancement in this field is the functionalization of cellulose papers with antibodies, nucleic acids, and nanomaterials in PBBs (paper-based bioassays) and μPADs (microfluidic paper-slip devices). Hence, the application of 2D materials and cellulose in medical diagnostics and biosensors has shown great potential. These materials have unique properties that make them suitable for various applications, including disease detection, real-time monitoring, and point-of-care diagnostics.
  • 265
  • 04 Jan 2024
Topic Review
Aerogel
Aerogels are one of the most interesting materials of the 21st century owing to their high porosity, low density, and large available surface area. Historically, aerogels have been used for highly efficient insulation and niche applications, such as interstellar particle capture. Recently, aerogels have made their way into the composite universe.
  • 1.2K
  • 14 Feb 2022
Topic Review
AFM imaging of extracellular vesicles
Advanced and optimised microscopy methods, including atomic force microscopy (AFM), are required to visualise and characterise morphology of extracellular vesicles (EVs), a heterogenous groups of nanoparticles regarded as highly promising source of diagnostic, prognostic, and therapeutic tools. EVs are nanosized phospholipid membranous structures ubiquitously found in human biofluids, secreted from almost every cell, and thus reflect both physiological and pathophysiological changes of their parental cells. The lipid membrane of an EV contains proteins (e.g., tetraspanins, receptors and other molecules) and diverse luminal content with bioactive cargo that includes nucleic acids (DNA, mRNA, miRNA and lncRNA), proteins, organelles, or infectious particles.  AFM is a nanoscale tool for the determination of morphology, structure and composition, but also biomechanics and biophysical characteristics of nanometric structures. Briefly, AFM uses a micrometric cantilever with a nanometre-sized tip actuated by piezoelectric crystals. Upon receiving signals of a tip-sample interaction, a position-sensitive photodiode (PSPD) converts it to a voltage and sends it to a piezoelectric actuator (PA). The latter expands and contracts proportionally to the applied voltage to manipulate the sample and the probe position across three dimensions with high precision. The PA can be coupled to a cantilever or positioned under a sample holder. The whole system is controlled by suitable control electronics.
  • 1.2K
  • 11 Oct 2021
Topic Review
AI-Based Nano-Scale Material Property Prediction for Li-Ion Batteries
The status quo for techniques used in the discovery of new and novel materials to enhance battery technologies has progressed from expensive and time-consuming empirical trial and error methods to the more recent first principles approach of using quantum mechanics (QM), Monte Carlo simulations and molecular dynamics (MD). QM calculations evaluate electron–electron interactions bby solving the complex Schrödinger equation, thereby enabling accurate results for a wide variety of properties. The emergence of ML, deep learning (DL) and artificial intelligence (AI) has helped alleviate the bottlenecks posed by QM and MD simulations and has made it possible to expand the scope of the search for novel materials in the chemical compound space (CCS) .
  • 131
  • 23 Feb 2024
Topic Review
Albumin Nanostructures in Cancer
Albumin is a versatile protein being used widely for developing carriers for drugs and nucleic acids. It provides biocompatibility, tumor specificity, the possibility for surface modification, and reduces toxicity. 
  • 622
  • 23 Jul 2021
Topic Review
Amperometric Biosensors and Biofuel Cells
Amperometric biosensors and biofuel cells are mostly based on immobilized enzymes or living cells. Among the many oxidoreductases, glucose oxidase (GOx) is used mostly in biosensor design. The same GOx can be well applied for the development of biofuel cells and self-charging capacitors based on the operation of biofuel cells. 
  • 768
  • 24 Aug 2021
Topic Review
Analytical Techniques for Detection of Quantum Dots
Since the discovery of Quantum Dots (QDs) by Alexey I. Ekimov in 1981, the interest of researchers in that particular type of nanomaterials (NMs) with unique optical and electrical properties has been increasing year by year. Thus, since 2009, the number of scientific articles published on this topic has not been less than a thousand a year. The increasing use of QDs due to their biomedical, pharmaceutical, biological, photovoltaics or computing applications, as well as many other high-tech uses such as for displays and solid-state lighting (SSL), has given rise to a considerable number of studies about its potential toxicity. However, there are a really low number of reported studies on the detection and quantification of QDs, and these include ICP–MS and electrochemical analysis, which are the most common quantification techniques employed for this purpose. Keeping in mind both human health and environmental risks of QDs as well as the scarcity of analytical techniques and methodological approaches for their detection, the adaptation of existing techniques and methods used with other NMs appears necessary. 
  • 524
  • 27 Jul 2022
Topic Review
Anodic Films of Mg Alloys
This entry presents an overview of the recent developments in the synthesis of layered double hydroxide (LDH) on the anodized films of Mg alloys prepared by either conventional anodizing or plasma electrolytic oxidation (PEO) and the applications of the formed composite ceramics as smart chloride traps in corrosive environments.
  • 596
  • 02 Mar 2021
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